• Korean Journal of Clinical Laboratory Science
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• v.50 no.4
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• pp.391-398
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• 2018

Mesenchymal stem cells (MSCs) are an attractive resource for refractory patients because of their anti-inflammatory/immunomodulatory capability and multi-lineage differentiation potential. The transplantation of MSCs has led to positive results in preclinical and clinical application to various diseases, including autoimmune disease, cardiovascular disease, cancer, liver cirrhosis, and ischemic stroke. On the other hand, studies have shown that paracrine factors, not direct cell replacement for damaged cells or tissue, are the main contributors in MSC-based therapy. More recently, evidence has indicated that MSC-derived exosomes play crucial roles in regulating the paracrine factors that can mediate tissue regeneration via transferring nucleic acids, proteins, and lipids to the local microenvironment and cell-to-cell communication. The use of these exosomes is likely to be beneficial for the therapeutic application of MSCs because their use can avoid harmful effects, such as tumor formation involved in cell transplantation. Therefore, therapeutic applications using MSC-derived exosomes might be safe and efficient strategies for regenerative medicine and tissue engineering. This review summarizes the recent advances and provides a comprehensive understanding of the role of MSC-derived exosomes as a therapeutic agent.

• 재활복지
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• v.20 no.4
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• pp.135-156
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• 2016

The purpose of this study was to investigate item goodness-of-fit of Childhood Autism Rating Scale(CARS), Rasch rating scale model was applied to 15 items of the CARS in a sample of pervasive development disorder(n=238). An assumption to test Rasch Model, which is satisfaction of unidimensionality, is regarded through PCAR analysis, and jMetrik 4.03 program is used to test the goodness-of-fit of items. The results of this study were: First, 5-point rating scale was appropriate for the CARS rather than 7-point original rating scale. Second, the result of examining the CARS questions goodness-of-fit, there was a overfitting or misfitting items according to the classified groups. Only in particular Q11 item in diagnosis subject of integration population of autism has become inappropriate. Therefore, it is necessary to provide education for the CARS more systematically. Thirdly, the result of comparing the personal attributes score and difficulty of a CARS question, Q2, Q3, Q10, Q11 items are necessary to distinguish conceptually defined in more detail. Fourth, the results of investigating the difficulty of CARS question, it was found to exhibit a verbal communication is most serious problem for the population of autism.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.256-259
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• 2016

The growth of mobile devices in Internet of Things (IoT) leads to a number of intelligent buildings related IoT applications. For instance, home automation controlling system uses client system such web apps on smartphone or web service to access the home server by sending control commands. The home server receives the command, then controls for instance the light system. The gateway based RESTful technology responsible for handling clients' requests attests an internet latency in case a large number of clients' requests submit toward the gateway increases. In this paper, we propose the design tasks of the IoT gateway for handling concurrency events. In the procedure of designing tasks, concurrency is best understood by employing multiple levels of abstraction. The way that is eminently to accomplish concurrency is to build an object-oriented environment with support for messages passing between concurrent objects. We also investigate the performance of event-driven architecture for building IoT gateway using node.js on one side and communication protocol based message-oriented middleware known as XMPP to handle communications of intelligent building control devices connected to the gateway through a centralized hub. The Node.JS is 40% faster than the traditional web server side features thread-based approach. The use of Node.js server-side handles a large number of clients' requests, then therefore, reduces delay in performing predefined actions automatically in intelligent building IoT environment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.277-280
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• 2016

Currently, systems for finding missing children are composed of using communication between a QR code and RFID chip, as the use of a smartphone. However, the current systems for finding missing children have limitations in that children can only be found if there are people in the surrounding area; there is an economic burden on parents required to purchase a smartphone for their children; along with difficulties in finding the missing children without the assistance of those in the surrounding area in critical situations such as a kidnapping, due to the limited duration of the battery life. In order to solve such problems, approaches need to be made from two perspectives: having someone in the surrounding area; and absence of anyone in the surrounding area. This thesis is centered on the development of a IoT (Internet of Things) system for finding missing children that combines two methods, namely, the method of finding missing children without a guardian in the surrounding area -within the limited space in which AP is installed by using a beacon and open source hardware being highlighted as the IoT technology - and the method of finding missing children with the smartphone application in which each individual becomes the Access Point (AP). The Main purpose is to provide accurate information of missing children's location for the 2situations and it is found that the accuracy of smartphones APP is 97.7% and security device AP is 91.1%.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.867-870
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• 2014

Currently a number of universities and other educational institutions in the e-learning education system being implemented. Also that there is a demand. However, existing e-learning system has many problems. First, the theory of how the university -centered education and training institutions to adopt e-learning system has become the biggest obstacle. In addition, students can not engage the problem of a one-way lecture. In this paper, the theory -oriented and practice to overcome the one-way river systems programming language will develop e-learning content. Using socket communication and multi-threaded server-side Web browser on the client side through the compiler without installing a separate application installation and environmental learning environment can be unrestricted. Hands- content programming language allows the learner to direct the client-side source code in a web browser by entering the lecture is leading the way. For learners to enter the source code compiled to run on the server side, the compiler provides the learner results. Hands- because the future e-learning content development in e-learning systems will be a major contribution to.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.299-302
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• 2014

Due to the convergence between digital devices and the development of wireless communication technology, bit-signal sensor miniaturization, building an Electronic Medical Record (EMR) which is a digital version of a paper chart that contains all of a patient's medical history and the information of Electronic Health Record (EHR), Ubiquitous healthcare (u-Healthcare) that can monitor their health status and provide personal healthcare service anytime and anywhere. Also, the appearance of cloud computing technology is one of the factors that accelerate the development of u-healthcare service. However, if the individual information to be used maliciously during the u-healthcare service utilization, leads to serious problems directly related to the individual's life because if it goes beyond the level of simple health screening and treatment, it may not provide accurate and reliable healthcare services. For this reason, we analyzed a variety of security issues related to u-healthcare service in cloud computing environment and described about directions of secure health information sharing system construction. In addition, we suggest the future developmental direction for th activation of u-healthcare industry.

• Journal of Digital Convergence
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• v.17 no.9
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• pp.249-259
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• 2019

The purpose of this study is to analyze the effects of college adjustment, character, communicative competence, and interpersonal competence on field practice adaptation of college student. Subjects were 231 nursing students and medical students in J city and C city, G-do. Using SPSS/WIN 20.0, multiple regression analysis using Baron & Kenny's three-step procedure and Sobel test were used to verify the significance of the mediator effect. The variables directly affecting field practice adaptation were college adjustment (${\beta}=.22$, p=.003) and interpersonal competence (${\beta}=.38$, p<.001). Character and Communicative competence did not have a direct affect on field practice adaptation (${\beta}=.02$, p=.740), (${\beta}=.04$, p=.590) but indirect effect through interpersonal competence was significant(${\beta}=.15$, p=.004), (${\beta}=.19$, p=.011). As character and communicative competence are the variables affecting field practice adaptation through interpersonal competence, training programs to improve character, communicative competence, and interpersonal competence in college are needed.

• Journal of the Korean Data Analysis Society
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• v.20 no.6
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• pp.3117-3126
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• 2018

The operating system update is a basic step to maintain a safe internet use environment. This study analyzed whether the implementation of the operating system update was related to gender and age group during the violation accident prevention act in relation to information protection on the internet, and tried to verify the validity of these factors by analyzing the influence of gender and age group. In this study, logistic regression analysis was conducted based on the information security survey data surveyed by the Korea Internet & Security Agency in 2016. As a result, gender and age were surveyed as factors related to the implementation of operating system updates. As a result of analyzing the impact on the implementation of operating system updates by gender, it is estimated that the odds are 0.419 times higher for women than for men. According to the analysis of the operating system update by age group based on the 50s, which is a vulnerable group of information, the result is that the odds are 13.266 times higher in the 20s than the 50s.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.45-54
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• 2022

This study examines the actual operation and performance of the public participation platform by analyzing various public participation processes from 2018 to 2021, when 'Gwanghwamun 1st Street', a representative public participation platform operated by the Ministry of Public Administration and Security, was launched. Through this, the influencing factors that were able to successfully induce the process of policyization through public participation were derived as follows. First, online participation channels were diversified to encourage public participation. Second, it is also important that the public opinion contest and compensation for public review were implemented to encourage and expand public participation. Third, the participation of experts was encouraged to refine and refine the people's ideas. Through these research results, it is judged that the Korean government will be able to contribute to inducing the policyization process through continuous public participation. In deriving success factors for policyization through public participation in the future, how influencing factors such as the public participation process, communication through online channels, and collaboration with experts affect the public participation process using quantitative analysis techniques A study to prove it will have to be conducted subsequently.

• Journal of Naturopathy
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• v.9 no.2
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• pp.62-70
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• 2020

Purpose: According to the Body-EU education program, this study investigates changes after conducting education with ten subjects with autism symptoms (disability level 2~3) 63 times (126 hours) for nearly two years. Methods: Body-EU habit practice, note writings discussion, singing, Bible study, question and communication, class arrangement, etc., a total of 63 times were educated for 2 hours each week. Results: Subjects felt comfortable breathing and improved energy. Other subject's habit of an out-toed gait step and bending back alleviated. One subject made it easier to speak, so if talking with no strength. When breathing, the stuffy nose improved, the eyes became calm, and the hands and feet were warm. Subject felt like my head was cleaned. Heart tightness disappeared. Subject felt at ease as gaining confidence. The subject gained confidence in seeing whoever the other person was. The subject's pronunciation became more sophisticated, with more confidence, and his mouth cramping alleviated. Subjects with right eye movements showed a relatively high concentration in education time. Conclusions: Subjects are educated and trained in making general habits of their body from morning to going to bed. This study was a research program for ordinary people, but it confirmed with autism. Whether it was genetic autism or acquired autism, they could be somewhat relieved.