• Proceedings of the Microbiological Society of Korea Conference
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• 2007.05a
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• pp.120-122
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• 2007

All living organisms use numerous signal-transduction pathways to sense and respond to their environments and thereby survive and proliferate in a range of biological niches. Molecular dissection of these signalling networks has increased our understanding of these communication processes and provides a platform for therapeutic intervention when these pathways malfunction in disease states, including infection. Owing to the expanding availability of sequenced genomes, a wealth of genetic and molecular tools and the conservation of signalling networks, members of the fungal kingdom serve as excellent model systems for more complex, multicellular organisms. Here, we employed Cryptococcus neoformans as a model system to understand how fungal-signalling circuits operate at the molecular level to sense and respond to a plethora of environmental stresses, including osmoticshock, UV, high temperature, oxidative stress and toxic drugs/metabolites. The stress-activated p38/Hog1 MAPK pathway is structurally conserved in many organisms as diverse as yeast and mammals, but its regulation is uniquely specialized in a majority of clinical Cryptococcus neoformans serotype A and D strains to control differentiation and virulence factor regulation. C. neoformans Hog1 MAPK is controlled by Pbs2 MAPK kinase (MAPKK). The Pbs2-Hog1 MAPK cascade is controlled by the fungal "two-component" system that is composed of a response regulator, Ssk1, and multiple sensor kinases, including two-component.like (Tco) 1 and Tco2. Tco1 and Tco2 play shared and distinct roles in stress responses and drug sensitivity through the Hog1 MAPK system. Furthermore, each sensor kinase mediates unique cellular functions for virulence and morphological differentiation. We also identified and characterized the Ssk2 MAPKKK upstream of the MAPKK Pbs2 and the MAPK Hog1 in C. neoformans. The SSK2 gene was identified as a potential component responsible for differential Hog1 regulation between the serotype D sibling f1 strains B3501 and B3502 through comparative analysis of their meiotic map with the meiotic segregation of Hog1-dependent sensitivity to the fungicide fludioxonil. Ssk2 is the only polymorphic component in the Hog1 MAPK module, including two coding sequence changes between the SSK2 alleles in B3501 and B3502 strains. To further support this finding, the SSK2 allele exchange completely swapped Hog1-related phenotypes between B3501 and B3502 strains. In the serotype A strain H99, disruption of the SSK2 gene dramatically enhanced capsule biosynthesis and mating efficiency, similar to pbs2 and hog1 mutations. Furthermore, ssk2, pbs2, and hog1 mutants are all hypersensitive to a variety of stresses and completely resistant to fludioxonil. Taken together, these findings indicate that Ssk2 is the critical interface protein connecting the two-component system and the Pbs2-Hog1 pathway in C. neoformans.

• Korean Journal of Construction Engineering and Management
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• v.16 no.3
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• pp.11-23
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• 2015

Construction Management(CM) and Building Information Management(BIM) have a lot in common that they need to establish a cooperation system among different disciplines and promote smooth communication among project stakeholders throughout the project life-cycle. BIM can be an effective information management tool for CM's business and improve their service value. However, BIM uses by Construction Managers(CMr) are very limited. The objective of this study is to analyze the intention of CMrs to adopt BIM and establish effective BIM use strategy in the CMr's point of view. This study utilizes Technology Acceptance Model(TAM) as a research method, and the results show that 1) CMrs think it is more important whether BIM is required to be adopted in their business process at the social or industry level than that BIM can improve their personal competence, recognition, and impressions through their voluntary BIM adoption; 2) that CMrs think it is important to figure out business processes where BIM can be smoothly incorporated; and 3) that CMrs hesitate the use and trial of BIM in their realworld business although they agree that BIM needs to be eventually adopted in their business in the future. Based on these results, directions for establish a strategy for BIM adoption were proposed at the CMr's point of view

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.2
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• pp.299-306
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• 2016

In this paper, a method of shape prediction of an endoscope handling robot that can imitate a surgeon's behavior using a sensor network is suggested. Unit sensors, which are composed of a 3-axis magnetometer and 3-axis accelerometer pair comprise the network through CAN bus communication. Each unit of the sensor is used to detect the angle of the points in the longitudinal direction of the robot, which is made from a flexible tube. The signals received from the sensor network were filtered using a low pass Butterworth filter. Here, a Butterworth filter was designed for noise removal. Finally, the Euler angles were extracted from the signals, in which the noise was filtered by the low path Butterworth filter. Using this Euler angle, the position of each sensor on the sensor network is estimated. The robot body was assumed to consist of links and joints. The position of each sensor can be assumed to be attached to the center of each link. The position of each link was determined using the Euler angle and kinematics equation. The interpolation was carried out between the positions of the sensors to be able to connect each point smoothly and obtain the final posture of the endoscope in operation. The experimental results showed that the shape of the colonoscope can be visualized using the Euler angles evaluated from the sensor network suggested and the shape of serial link estimated from the kinematics chain model.

• Journal of Distribution Science
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• v.13 no.5
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• pp.91-102
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• 2015

Purpose - This study aims to build a systematic frame for effective marketing performances by prioritizing product type and pertinent channel that are appropriate for digital channel characteristics. FCB grid model was used to define a product type, and Internet communication satisfaction index was considered as a marketing performance measuring tool for digital channel. Research design, data, and methodology - As systematic understanding for Digital marketing is still unfamiliar to even professional marketer, the hypothesis was established based on preliminary research by conducting a qualitative survey of marketing experts who already experienced digital marketing in the fields as well as existing related study literature. Through a preliminary research, the degree for understanding for digital marketing, current digital marketing (including product/channel mix) execution status, and difficulties for marketers who had experienced digital marketing were figured out. Based on preliminary research, the main part of survey was designed to examine which type of product would be effective for digital marketing and which digital channel would be effective to achieve marketing performance in line with marketing objectives. To collect data, the questionnaire survey was conducted for professional marketers who had experienced digital marketing in 10 different fields including FMCG, cosmetics, distribution industry for one month (July, 10, 2014~Aug, 10, 2014). A total of 90 questionnaire were distributed and 66 questionnaires were used for the analysis, excluding the unanswered and insincere questionnaires. The data were analysed using SPSS ver.18.0. Results - The analysis for product type which is pertinent to digital marketing and prioritization for digital channel per digital marketing performance type could be summarized as followings. First, high involvement buying decision type of product and rational purchasing decision type of product in FCB grid are more effective for digital marketing in terms of marketing performance. Therefore, marketers in field would prioritize considering product type before executing digital marketing. Second, factor for sales increase, potential consumer creation and brand awareness was represented respectively 31.25%, 21.9%, and 20.8% as a result of factor analysis in terms of digital marketing channel performance. Third, effective major digital channel per digital marketing performance factor was differently identified as each digital channel has its own peculiarity. For instance, search engine is more effective for increasing sales while social media such as facebook and Kakaotalk is more effective for encouraging consumer participation. Conclusions - As a result of this study, product type and peculiarity which were pertinently fit to digital marketing were identified by using FCB grid model, and also suggested framework for decision making of digital channel selection in line with marketing objectives for effective marketing performance. It also provided insight to professional marketer which type of product could be effective for digital marketing execution as well as which factors should be measured for digital marketing performance.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.6
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• pp.553-558
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• 2011

This paper describes the development and test result of S-band Transmitter flight model(FM) of STSAT-3 by satellite research center(SaTReC), KAIST. The communication sub-system of STSAT-3 is consist of two different frequency band channels, S-band for Telemetry & Command and X-band for mission data. S-band Transmitter(STX) functionally made of modulator, frequency synthesizer, power amp and DC/DC converter. The transmission data is modulated by FSK(Frequency Shift Keying) and the interface between spacecraft sub-module and STX is RS-422 standard method. The FM STX is based on modular design. The RF output power of STX is 1.5W(31.7dBm) and BER of STX is under $1{\times}10^{-5}$ which meets the specification respectively. The FM STX is delivered Spacecraft Assembly, Integration and Test(AIT) level through the completion of functional Test and environmental(vibration, thermal vacuum) Test successfully.

• Journal of Internet Computing and Services
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• v.19 no.1
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• pp.37-47
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• 2018

The number of capabilities of Internet of Things (IoT) devices will exponentially grow over the next years. These devices may generate a vast amount of time-constrained data. In the context of IoT, data management should act as a layer between the objects and devices generating the data and the applications accessing the data for analysis purposes and services. In addition, most of IoT services will be content-centric rather than host centric to increase the data availability and the efficiency of data delivery. IoT will enable all the communication devices to be interconnected and make the data generated by or associated with devices or objects globally accessible. Also, fog computing keeps data and computation close to end users at the edge of network, and thus provides a new breed of applications and services to end users with low latency, high bandwidth, and geographically distributed. In this paper, we propose Edge-Fog cloud-based Hierarchical Data Delivery ($EFcHD^2$) method that effectively and reliably delivers IoT data to associated with IoT applications with ensuring time sensitivity. The proposed $EFcHD^2$ method stands on basis of fully decentralized hybrid of Edge and Fog compute cloud model, Edge-Fog cloud, and uses information-centric networking and bloom filters. In addition, it stores the replica of IoT data or the pre-processed feature data by edge node in the appropriate locations of Edge-Fog cloud considering the characteristic of IoT data: locality, size, time sensitivity and popularity. Then, the performance of $EFcHD^2$ method is evaluated through an analytical model, and is compared to fog server-based and Content-Centric Networking (CCN)-based data delivery methods.

• Journal of Internet Computing and Services
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• v.19 no.1
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• pp.49-66
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• 2018

This research explores a value chain structure of VR-AR media including user's perception, uses, and evaluation. The purpose of this research focused on factor analysis and the relationship among user's VR-AR adoption motivations and utilities. This research explores correlation between personal value and using motivation. This study was to identify the value structure of respondent on VR-AR usages based on means-end chain theory. The research used structured APT laddering questions and 251 data was analysed. Through such analysis, category difference by stage and relationship difference were identified and hierarchical value map was compared. There are four different value ladders: first is attributes, functional consequences, psychological consequences, and final value. This study is based on the analysis of the value chain structure factors that affect VR and AR use behavior (attributes, functional benefits, psychological benefits, use value), 'Hierarchical Value Map' between users' The purpose of the model is to construct a model. For this, 'means-end chain theory' was applied to measure the causal relationship between personal value and VR related use behavior. In order to solve this research problem, 135 people were analyzed through the structured questionnaire using the AR and VR content fitness measure and the second APT laddering, and the use of VR-AR : 1) Functional benefits; 2) Psychological benefits; 3) Means to reach value, 4) Objective value chain structure was identified. The results show that VR users tried to smooth the social life through the new virtual reality audiovisual element, the newness of experience, fun, and pleasure through the departure of reality, vividness of experience, and leading fashion. The AR fitness was a game and a new program, and the value of interacting with other people and the value of 'periwinkle' played an important role through the vividness and peripheral interaction of AR, It was an important choice. The important basic values of users' VR and AR selection were correlated with psychological attributes of interaction with others, achievement, happiness and favorable values.

• Korea Journal of Hospital Management
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• v.22 no.2
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• pp.28-43
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• 2017

The purpose of this study was to investigate the influence of professional self-concept and interpersonal relations on nursing competence of clinical nurses. This study was conducted as a descriptive cross sectional survey with 182 nurses who work at a tertiary hospital which has over 1,000 beds, located in Gyeounggi - do. The data was collected from October 11th, 2016 to October 28th, 2016. The main findings of this study were as follows. The mean score for professional self-concept was $2.65{\pm}0.29$ points in the range of 1 point to 4 points. And interpersonal relations was an average of $3.55{\pm}0.35$ points in the range of 1 point to 5 points. Nursing competence was an average of $2.65{\pm}0.39$ points in the range of 1 point to 4 points. Professional self-concept and interpersonal relations were positively correlated with nursing competence. Nursing competence was differed from clinical career(F=10.518, p<.001), working unit(F=4.139, p=.018), educational background(F=6.542, p=.002), and satisfaction on nursing(F=6.326, p<.001). The regression model with clinical career, working unit, educational background, satisfaction on nursing, 3 sub domain of professional self-concept(professional practice, satisfaction, communication), and interpersonal relation was statistically significant (F=31.94, p<.001). And this model could explain 51.5% of nursing competency(Adj R2=.515). Especially, professional practice(${\beta}=.532$, p<.001) of professional self-concept, interpersonal relations(${\beta}=.223$, p<.001), clinical career(${\beta}=.169$, p<.001), working unit: ICU (${\beta}=.169$, p<.05) were identified the factors influencing on nursing competence. Therefore, improving clinical nurses' nursing competence can be achieved with broad approach that includes improvements in professional self-concept and interpersonal relations. And also, working unit, and clinical career should be considered to develop the actual program for nursing competence, too.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.2C
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• pp.206-216
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• 2012

Today's war fields can be characterized by net-centric wars where a variety of independent weapon systems are operated in connection with each other via networks. As such, weapon systems become dramatically advanced in terms of complexity, functionality, precision and so on. It is then obvious that the defense R&D of those requires systematic and efficient development tools enabling the effective management of the complexity, budget/cost, development time, and risk all together. One viable approach is known to be the development methods based on systems engineering, which is already proved to successful in U.S. In this paper, a systems engineering approach is studied to be used in the conceptual design of advanced weapon systems. The approach is utilizing some graphical models in the design phase. As a target system, an unmanned aerial vehicle system is considered and the standard SysML is also used as a modeling language to create models. The generated models have several known merits such as ease of understanding and communication. The interrelationships between the models and the design artifacts are identified, which should be useful in the generation of some design documents that are required in the defense R&D. The result reported here could be utilized in the further study that can eventually lead to a full-scale model-based systems engineering method.

• Journal of Distribution Science
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• v.15 no.6
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• pp.65-76
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• 2017

Purpose - The quality of customer service has been importantly considered as a way of retaining current customers. Recent development of service industry which based on Information & Communication Technology allows firms to utilize different employees for their businesses. Although it is regarded as important to consider emotional labor of employees working for customers in ICT service industry, little was known the role of emotional dissonance. Thus, current paper focused on emotional labor and tried to identify the factors which influence on employees' intrinsic motivation for married women working in call centers. This study highlighted the influence of the emotional dissonance on the employees' intrinsic motivation, and the moderating influences of work-family conflict on the relationship between emotional dissonance and intrinsic motivation. Research design, data, and methodology - The research samples were gathered from seven call centers of Korean financial institutions located in South Korea. The model of emotional dissonance was developed, which emphasizes the influence of emotional dissonance as a predictor on intrinsic motivation, and then the other model was also introduced to explain how employees' intrinsic motivation were aggravated by work-family conflict. To examine these research models, samples were collected from 468 married women working in call centers of Korean financial institutions located in Seoul. A total of 468 samples were used in the analysis after deleting data of missing value. SPSS 22.0 were utilized for data analysis. Results - The results of current study showed that emotional dissonance is negatively related to intrinsic motivation, and there are significant differences in work-family conflict. Those results generally support the proposed hypotheses. Conclusions - These results suggest that the relationship of intrinsic motivation of married women working in call center for customers' service were influenced by emotional dissonance, which outcomes were interacted not by face-to-face contact with their customers, but by emotional contacts. Managerially, these findings suggest the one who emphasize the quality of customer's service of call center need to introduce the programs for minimizing both of emotional dissonance and work-family conflict. These findings also suggest that the service quality via intrinsic motivation of married women working in call center is hard to be accomplished without considering the factors of emotional dissonance and work-family conflict.