Journal of the Korea Academia-Industrial cooperation Society
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v.22
no.3
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pp.460-469
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2021
Many people today suffer from stress originated from diseases, daily life, workplace, or environmental pollution. People want a comfortable and stable life along with physical and mental relaxation. As the number of people pursuing a comfortable life increases, terms of well-being and wellness have become more common, and wellness-related industries are also developing. Among the wellness and well-being industries, the wellness entertainment contents are one of the highest growing industries. This study aims to investigate how wellness contents contribute to improving the psychological well-being level of users through the mediating effect of telepresence in online. Specifically, this study suggests a hypothesized research model on the influence of online wellness entertainment content, which consists of sensory-, emotional-, and cognitive-attributes, on telepresence, followed by psychological well-being and word-of-mouth. With an empirical test using data on the experience of meditation app experience for 305 people, the result showed that the hypotheses in the research model were supported. The result of this study showed that wellness content induces users' telepresence and word-of-mouth, suggesting that wellness contents are needed to develop into a profit model rather than being limited to simple mental and physical stability.
Korean Journal of Construction Engineering and Management
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v.22
no.2
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pp.31-41
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2021
The purpose of this study is to analyze the properties of previous studies related to vocations in the construction field. The results of the analysis are as follows. First, The paper has not been published at the beginning of the establishment of the academic foundation for vocational studies, but there was a marked increase over the next 15 years. Second, research related to vocations in the construction field has been more active in engineering than in social science. Third, the primary data method was used much more than the secondary data method, and the quantitative research method through a questionnaire was the most common research method. Fourth, human objects showed the highest frequency as 78.9%, and among them, technicians was the most. Fifth, as the research topic, psychological and behavioral aspects such as job satisfaction, job stress, turnover intention, and organizational commitment were dealt with most, and structural and environmental aspects such as national job competency standards, job analysis, construction accidents, and career development. It was also found that the topic of the research was actively being dealt with.
Journal of the Korea Academia-Industrial cooperation Society
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v.21
no.12
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pp.639-650
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2020
The purpose of this study was to investigate perceptions of mental health literacy, mental health status, mental health welfare center and mental health business of local public officials. The participants were 762 public officials working in G city. Data were collected from October 1, to October 26, 2019 using structured questionnaires, and IBM SPSS 24.0 statistics program was used for the analysis. As a result, the mental health status of the subjects was the most severe stress 28.1%. The mental health literacy score of the subjects was 40.99 points and mental health status was 1.66 points. And 46.6% of the respondents had never heard of mental health welfare center. As for mental health business, 57.0% had never heard of mental health counseling, and the most common route for gaining information on mental health or mental illness was TV at 65.2%. In addition, 85.0% answered that an increase in the government budget for the management of mental health and illness was necessary. Therefore, it is necessary to strengthen the continuous education and promotion for mental health improvement and the development of customized mental health promotion programs suitable for the public officials level through of the community mental health welfare center.
Background: The incidence of ischemic cerebrovascular disease is increasing in recent years and has been one of the leading causes of neurological dysfunction and death. Ginsenoside Rg1 has been found to protect against neuronal damage in many neurodegenerative diseases. However, the effect and mechanism by which Rg1 protects against cerebral ischemia-reperfusion injury (CIRI) are not fully understood. Here, we report the neuroprotective effects of Rg1 treatment on CIRI and its possible mechanisms in mice. Methods: A bilateral common carotid artery ligation was used to establish a chronic CIRI model in mice. HT22 cells were treated with Rg1 after OGD/R to study its effect on [Ca2+]i. The open-field test and poleclimbing experiment were used to detect behavioral injury. The laser speckle blood flowmeter was used to measure brain blood flow. The Nissl and H&E staining were used to examine the neuronal damage. The Western blotting was used to examine MAP2, PSD95, Tau, p-Tau, NOX2, PLC, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging was used to test the level of [Ca2+]i. Results: Rg1 treatment significantly improved cerebral blood flow, locomotion, and limb coordination, reduced ROS production, increased MAP2 and PSD95 expression, and decreased p-Tau, NOX2, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging results showed that Rg1 could inhibit calcium overload and resist the imbalance of calcium homeostasis after OGD/R in HT22 cells. Conclusion: Rg1 plays a neuroprotective role in attenuating CIRI by inhibiting oxidative stress, calcium overload, and neuroinflammation.
Background: As trade increases, the influx of various alien species and their spread to new regions are prevalent and no longer a special problem. Anthropogenic activities and climate changes have made the distribution of alien species out of their native range common. As a result, alien species can be easily found anywhere, and they have nothing but only a few differences in intensity. The prevalent distribution of alien species adversely affects the ecosystem, and a strategic management plan must be established to control them effectively. To this end, hot spots and cold spots were analyzed according to the degree of distribution of invasive alien plants, and major environmental factors related to hot spots were found. We analyzed the 10,287 distribution points of 126 species of alien plants collected through the national survey of alien species by the hierarchical model of species communities (HMSC) framework. Results: The explanatory and fourfold cross-validation predictive power of the model were 0.91 and 0.75 as AUC values, respectively. The hot spots of invasive plants were found in the Seoul metropolitan area, Daegu metropolitan city, Chungcheongbuk-do Province, southwest shore, and Jeju island. Generally, the hot spots were found where the higher maximum temperature of summer, precipitation of winter, and road density are observed, but temperature seasonality, annual temperature range, precipitation of the summer, and distance to river and sea were negatively related to the hot spots. According to the model, the functional traits accounted for 55% of the variance explained by the environmental factors. The species with higher specific leaf areas were more found where temperature seasonality was low. Taller species preferred the bigger annual temperature range. The heavier seed mass was only preferred when the max temperature of summer exceeded 29 ℃. Conclusions: In this study, hot spots were places where 2.1 times more alien plants were distributed on average than non-hot spots (33.5 vs 15.7 species). The hot spots of invasive plants were expected to appear in less stressful climate conditions, such as low fluctuation of temperature and precipitation. Also, the disturbance by anthropogenic factors or water flow had positive influences on the hot spots. These results were consistent with the previous reports about the ruderal or competitive strategies of invasive plants instead of the stress-tolerant strategy. The functional traits are closely related to the ecological strategies of plants by shaping the response of species to various environmental filters, and our result confirmed this. Therefore, in order to effectively control alien plants, it is judged that the occurrence of disturbed sites in which alien plants can grow in large quantities is minimized, and the river management of waterfronts is required.
Journal of the Korea Society of Computer and Information
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v.27
no.12
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pp.259-266
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2022
In this paper, we propose a study is to prepare basic data for integrated health promotion education by preventing dry mouth and dry eyes through lifestyle management. From October 7 to 17, 2022, a total of 516 respondents who voluntarily agreed and responded through a self-written structured questionnaire were statistically analyzed for university students in their 20s across the country. As for the factor of feeling dry mouth among the living habits of the study subjects, the more smoking per day, the higher(8.41±2.041) and very high(7.75±2.927) felt dry mouth(p=.015), and the time spent using smart phones. The shorter this was, the lower(1.16±0.784) and very low(1.83±1.672) felt dry mouth(p=.022). The main factors contributing to dry mouth and dry eyes were dry eyes (odds ratio 3.651, p=.000), and high smoking(odds ratio 0.916, p=.038), and the more you use your smart phone (odds ratio 0.256, p=.004), the more you feel dry mouth. When feeling dry eyes, they felt dry mouth more(odds ratio 4.002, p=.000), and the more they exercised, the more dry eyes they felt(odds ratio 1.600, p=.009). As a result, since dry mouth and dry eyes appear as common inconveniences, it was found that lifestyle management is necessary to maintain and promote a healthy life. Therefore, it is proposed to build an integrated health platform that can improve the quality of life and implement personalized health management programs.
Yoon Gyung Kwon;Ji Young Yoon;Hanon Lee;Dong Hyo Kim;Jun Hyo Lee;Diane M Thiboutot;Dae Hun Suh;Byoung Jun Park
Journal of Life Science
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v.33
no.4
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pp.343-348
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2023
Acne is one of the most common skin diseases, mainly occurring in adolescence. The pathophysiology of acne involves not only hormonal, genetic and environmental factors, but also other factors including hyperseborrhea, inflammation, over-keratinization of follicular keratinocytes and overgrowth of Cutibacterium acnes (C. acnes). Cannabidiol (CBD) is known to relieve pain, stress and inflammation. Moreover, cannabis extracts containing CBD have been reported to be effective in treating acne. However, the therapeutic effect of CBD on acne remains unclear. Therefore, this study aimed to investigate the effect and mechanism of CBD on lipogenesis in SEB-1 sebocytes. We treated sebocytes with CBD and found that it not only inhibited lipid synthesis, but also inhibited cell proliferation by inducing apoptosis. We then demonstrated that sterol response element-binding protein-1 (SREBP-1) mediates the inhibitory effect of CBD on lipogenesis. Furthermore, Akt and adenosine monophosphate-activated protein kinase (AMPK), upstream regulators of SREBP-1, were regulated by CBD treatment. Taken together, our studies demonstrate that CBD inhibits adipogenesis by regulating the Akt/AMPK-SREBP-1 signaling pathway, providing potential for use as a therapeutic agent for acne. Further research is needed to confirm the effect of CBD on inflammation caused by hyperkeratosis, which will increase the possibility of using CBD for acne treatment.
KSCE Journal of Civil and Environmental Engineering Research
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v.28
no.4A
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pp.475-485
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2008
This paper intends to enhance the reliability and performance of domestic elastomeric bearings through the proposal of directions for the improvement of their stiffness regard to the Korean industrial standard KS F 4420 relative to the evaluation of design/fabrication/quality. Therefore, comparative analysis of the compressive elastic modulus, stiffness measurement method and performance evaluation method of KS F 4420 with those of Eurocode, Japanese bearing manual, and ISO code was performed, and measurement tests on the compressive stiffness and shear stiffness of common elastomeric bearings produced in Korea were conducted. The experimental results reveal that differences of about 20% and 13% occurred respectively for the compressive stiffness and shear stiffness according to the definition adopted for the stiffness. The measured values for the stiffness of the domestic elastomeric bearings were also verified to exhibit large deviation from the formula proposed by KS F 4420. Elastomeric bearings that does not have appropriate compressive stiffness required at the design can result in uneven deflection at supports of bridges and excessive stress in girders. Accordingly, the establishment of compressive elastic modulus formula and performance evaluation criteria fitted to the domestic circumstances through the execution of performance evaluation of bearings presenting diversified shapes and shape factors appears to be necessary for the domestic bearings to meet the performance required in design.
Adult child caregivers and spousal caregivers might deal with differential challenges. Studies about caregivers' psychological outcomes, however, tended to investigate associations between caregiving and its outcomes by pooling adult child caregivers and spousal caregivers together. By using a U. S. sample of family caregivers who assisted a relative with dementia, this study examined whether the relationship of caregivers to care receivers (daughter caregivers or spousal caregivers) made a difference in levels of depressive symptoms. The result showed that wife caregivers were more likely to be depressed than daughter caregivers. For daughter caregivers, role overload, role captivity, and behavior problems significantly influenced on depression. Besides these variables, the level of education was a significant predictor for wife caregivers. Role captivity and behavior problems significantly impacted on depression for husband caregivers. Thus, role captivity and behavioral problems were common predictors for all the caregivers. Specifically, higher levels of role captivity and behavioral problems were likely to make caregivers more depressed. The implication of these results were discussed.
Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS monitoring have been used mainly to detect reduced perfusion of the brain during orthostatic stress for three common forms of orthostatic intolerance (OI); orthostatic hypotension, neurally mediated syncope, and postural orthostatic tachycardia syndrome. Autonomic function testing is an important diagnostic test to assess their autonomic nervous systems for patients with symptom of OI. However, these techniques cannot measure dynamic changes in cerebral blood flow. There are many experimentations about study of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurologic diseases (stroke, epilepsy and migraine) are ongoing. NIRS have been experimentally used in all stages of stroke and may complement the established diagnostic and monitoring tools. NIRS also provide pathophysiological approach during rehabilitation and secondary prevention of stroke. The hemodynamic response to seizure has long been a topic for discussion in association with the neuronal damage resulting from convulsion. One critical issue when unpredictable events are to be detected is how continuous NIRS data are analyzed. Besides, NIRS studies targeting pathophysiological aspects of migraine may contribute to a deeper understanding of mechanisms relating to aura of migraine. NIRS monitoring may play an important role to trend regional hemodynamic distribution of flow in real time and also highlights the pathophysiology and management of not only patients with OI symptoms but also those with various neurologic diseases.
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