• Parasites, Hosts and Diseases
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• 제45권4호
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• pp.301-306
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• 2007

We attempted to identify parasite DNA in the biliary stones of humans via PCR and DNA sequencing. Genomic DNA was isolated from each of 15 common bile duct (CBD) stones and 5 gallbladder (GB) stones. The patients who had the CBD stones suffered from cholangitis, and the patients with GB stones showed acute cholecystitis, respectively. The 28S and 18S rDNA genes were amplified successfully from 3 and/or 1 common bile duct stone samples, and then cloned and sequenced. The 28S and 18S rDNA sequences were highly conserved among isolates. Identity of the obtained 28S D1 rDNA with that of Clonorchis sinensis was higher than 97.6%, and identity of the 18S rDNA with that of other Ascarididae was 97.9%. Almost no intra-specific variations were detected in the 28S and 18S rDNA with the exception of a few nucleotide variations, i.e., substitution and deletion. These findings suggest that C. sinensis and Ascaris lumbricoides may be related with the biliary stoneformation and development.

• 대한한방내과학회지
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• 제44권4호
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• pp.803-813
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• 2023

Objective: This case report outlines an investigation into the efficacy of Korean medicine treatment in a patient who presented with acute cholangitis accompanying common bile duct stones. The patient underwent percutaneous transhepatic gallbladder drainage and subsequently experienced resolution of the common bile duct stones. Methods: The patient was treated with Shihosogan-tang, general acupuncture, ear acupuncture, moxibustion, and cupping therapy. Changes in symptoms were evaluated using a self-reported numerical rating scale (NRS) score and a visual analog scale (VAS) score each morning. Laboratory tests were conducted to examine serum amylase, serum lipase, and liver function. Results: After 29 days, the NRS scores for indigestion and fatigue and the VAS score for abdominal pain all decreased. Additionally, the laboratory test results showed improvement. Discussion: The results suggest that Korean medicine could be effective in treating symptoms of acute cholangitis. However, further research is necessary.

• Advances in pediatric surgery
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• 제13권1호
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• pp.37-44
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• 2007

A vitelline duct (VD) anomaly is a relatively common congenital abnormality of the umbilical area. The anomalies include patent vitelline duct (PVD), cyst, fistula or sinus. The incidence is approximately 2% of the populations, but development of symptoms is rare. Recently, we experienced two cases; PVD accompanied by a small omphalocele and intestinal volvulus due to mesenteric band between Meckel's diverticulum and the mesentery. Thereafter,we evaluated the data of vitelline duct anomalies for 27 years. From 1980 to 2006, 18 cases of VD anomalies were reviewed based on the hospital records retrospectively. There were 15 boys and 3 girls and age ranged from 2 days to 15 years. Among the 18 cases, 15 cases were symptomatic and consisted of Meckel's diverticulum (10 cases), PVD (4 cases) and umbilical polyp (1 case). Three asymptomatic cases of Meckel's diverticulum were found incidentally were and were observed without resection. Ten cases of Meckel's diverticulum were presented with intestinal bleedings (4 cases), intestinal obstructions (5 cases) and perforation (1 case). Wedge resections and segmental resections of ileum were performed in 8 patients and 2 patients, respectively. Postoperative complications were adhesive ileus (1 case) and wound seroma (1 case). Small omphaloceles were accompanied in two of 4 PVD patients. There was 1 small omphalocele case which was accompanied by a prolapse of ileum. In summary, VD anomalies were more common in male and more than half of them were found in patients less than 1 year of age. PVD was diagnosed most frequently in neonates. Meckel's diverticulum presented with intestinal obstruction more frequently than bleeding.

• 대한소화기학회지
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• 제72권6호
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• pp.318-321
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• 2018

Primary neuroendocrine tumors originating from the extrahepatic bile duct are rare. Among these tumors, large cell neuroendocrine carcinomas (NECs) are extremely rare. A 59-year-old man was admitted to Sanggye Paik Hospital with jaundice that started 10 days previously. He had a history of laparoscopic cholecystectomy, which he had undergone 12 years previously due to chronic calculous cholecystitis. Laboratory data showed abnormally elevated levels of total bilirubin 15.3 mg/dL (normal 0.2-1.2 mg/dL), AST 200 IU (normal 0-40 IU), ALT 390 IU (normal 0-40 IU), and gamma-glutamyl transferase 1,288 U/L (normal 0-60 U/L). Serum CEA was normal, but CA 19-9 was elevated 5,863 U/mL (normal 0-37 U/mL). Abdominal CT revealed a 4.5 cm sized mass involving the common bile duct and liver hilum and dilatation of both intrahepatic ducts. Percutaneous transhepatic drainage in the left hepatic duct was performed for preoperative biliary drainage. The patient underwent radical common bile duct and Roux-en-Y hepaticojejunostomy for histopathological diagnosis and surgical excision. On histopathological examination, the tumor exhibited large cell NEC (mitotic index >20/10 high-power field, Ki-67 index >20%, CD56 [+], synaptophysin [+], chromogranin [+]). Adjuvant concurrent chemotherapy and radiotherapy were started because the tumor had invaded the proximal resection margin. No recurrence was detected at 10 months by follow-up CT.

• KIEAE Journal
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• 제9권4호
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• pp.17-22
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• 2009

It is common to design the duct branches where to supply the required air flow for individual room in residential apartment house. However it is difficult to adjust the air volume adequately in small air duct branches in residential ventilation system. The purpose of this study is to figure out the performance of Multidrop chamber coupling system for the residential ventilation system. The experiments were designed to simulate apartment of $84m^2$ and established multidrop chamber duct and general duct on the ceiling of the apartment. Distribution performance of air supply rate were evaluated in this experiments. As a result, distribution performance of air supply rate in the general duct is different from designed air supply rate by about 35% ~ 50% and about 10% in the multidrop chamber system. In additional the sound insulation performance of the multidrop chamber system decreased about 20% compared with general duct system. Therefore, the multidrop chamber system is considered to satisfy proper air supply rate of each room and to improve the sound insulation performance in apartment Houses.

• Advances in pediatric surgery
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• 제7권2호
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• pp.137-141
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• 2001

Thyroglossal duct cyst is ectodermal remnant, which may develop along the line of descent of the thyroid gland from the foramen cecum of the tongue to the pyramidal lobe of the thyroid gland. Meticulous dissection of the cyst and duct, along with the body of the hyoid bone is necessary to avoid recurrence. Eighty-one patients with thyroglossal duct cyst treated at Hanyang University Hospital between January 1980 and December 2000 were reviewed to determine the incidence and to analyze the result of management. The male-to-female ratio was 1.4:1(47:34) with a male preponderance. They are most commonly present at 3-8years(54.2 %) of age, but rarely present at infancy. The most common symptom was a painless midline neck mass(76.5 %, 62cases). Eighty-one patients underwent modified Sistrunk operation without evidence of recurrence. Eight-nine percent(72 cases) of these lesions were located between thyroid substance and hyoid bone, and 11 %(9 cases) were above the hyoid bone. There were 22 infected cysts(27.2 %). The Sistrunk operation is a gold standard for treating the thyroglossal duct cysts. For best results in thyroglossal duct cyst surgery, one should make every effort to remove the cyst intact in continuity with the body of the hyoid bone. In our institute, Sistrunk operation modified by the authors showed a good result.

• 대한두경부종양학회지
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• 제34권2호
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• pp.47-51
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• 2018

Thyroglossal duct cyst is most common type of congenital cervical tumor. The suprahyoid thyroglossal duct cyst is a subtype of thyroglossal duct cyst and has different clinical characteristics. This subtype shows recurrent submental swelling and no tumor movement during swallowing or tongue protrusion. Because of these clinical differences, it is important to consider the possibility of thyroglossal duct cyst of in diagnosis and surgery of submental tumor. Recently, we have experienced two cases of suprahyoid type thyroglossal duct cyst with submental swelling and treated successfully by Sistrunk's operation.

• 한국지리정보학회지
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• 제14권4호
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• pp.1-12
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• 2011

도시 팽창과 신도시 개발로 도로, 전기, 상하수도 등의 7대 지하시설물의 안전에 대한 관심이 대두되고 있다. 특히 상하수도, 가스관 등을 수용하고 있는 공동구 설치 및 관리 방법이 대안으로 제시되고 있으나, 기존 공동구 시설은 국가 보안지역으로 묶여 관련 관리 기술에 대한 연구가 많이 이루어지지 못하였다. 특히 기존 인력에 의존하여 운영하는 현 방식은 실시간으로 긴박하게 발생하는 사건 사고에 적절히 대처하기 어려울 뿐만 아니라, 공동구내부에 화재 발생이나 가스유출 사고 발생 시 접근조차 불가능하며 사고에 대한 상황파악이나 대처가 어렵다. 그러므로 본 연구에서는 한국건설기술연구원내 설치되어 있는 실증실험장(TestLab)내에 설치되어 있는 공동구에서 무인 모니터링 장치를 설치하는 방법과 상수도관을 중심으로 시설물 관리 방법과 전체 모니터링을 위한 CCTV 영상 자료 처리 방법을 제안하고자 한다. 본 기술의 적용은 공동구내부에 실시간 모니터링이 가능하며, 사건 사고 발생 시 신속한 접근 및 대처가 가능하다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권2호
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• pp.81-93
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• 2006

Obstructive sialadenitis is one of common disease in salivary gland, and most common histologic features are loss of acinar cell and ductal dilatation associated with fibrosis, and infiltration of inflammatory cells. Although many experimental studies has been accomplished for the salivary acinar cell change in obstructive salivary gland disease, studies for myoepithelial cell were deficient. This study is designed for salivary gland tissue change, especially myoepithelial cell when nonspecific chronic sialadenitis or salivary duct injury by duct obstruction or cut can be occurred that is common encounted clinically. After ligation and cutting of submandibular gland of rabbit, groups of aminmal were sacrificed at 1, 2, 4 weeks postoperatively, submandibular gland were removed. The histopathologic evaluation was done with light microscopy. And, with immunohistochemical staining with ${\alpha}$-smooth muscle actin, characteristics of myoepithelial cell were examined. With transmission electron microscopy, ultrastructure of myoepithelial cell were examined for distribution and ultrastructure of myoepithelial cell. The results were obtained as follows: 1. In the histopathologic evaluation, ligation and cutting group of 1 week, linkage of myoepithelial cell associated with acinar atrophy and degeneration were disappeared in both group. 2. More prominent squamous metaplasia was seen in acinar cells of ligation group of 2 weeks experimental rabbit than cutting group. 3. Acinar cells are nearly disappeared in both ligation and cutting group of 4 weeks, and myoepithelial cell also disappeared associated with acinar cell atrophy, and duct-like structure composed by squamous cells by squamous metaplasia in acinar cells were distributed. 4. In immunohistochemical study, both ligation and cutting group ${\alpha}$-SMA distribution were diminished at 1 week experimental rabbits, but myoepithelial cell was more diminished in ligation group than cutting group, which were distributed around cells of squamous metaplasia. 5. Nuclear condensation, chromosome margination, and cytoplasmic vaculoation were appeared in myoepithelial cell of both cutting and ligation group after 1 week with transmission electron microscopy. But degenerative substance were seen in cytoplasm of myoepithelial cell of ligation group of 4 weeks. From the results obtained in this study, atrophy and degeneration of myoepithelial cell was more prominent in duct ligation group than duct cutting group, and myoepithelial cells were seen around cells squamous metaplasia of acinar cell.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2003년도 추계 학술대회논문집
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• pp.200-205
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• 2003

The Canard rotor/wing (CRW) aircraft concepts offer great potential for application by allowing the use of a common propulsion system for high-speed cruise and low-speed powered lift. Using the rotor for lift in both flight modes increases its utility. In the hovering mode, the exhausted gas from an gas turbine engine is accelerated through the duct system and it provides the tipjet power for rotor system enough to lift the aircraft. In the cruise mode, the rotor is fixed and the exhausted gas is extracted through the main nozzle, such that the aircraft is able to flight with high speed. The duct system was designed using 1-D fanno line flow theory and empirical data. However, the empirical data of the pressure loss coefficient for various bending and dividing ducts were not enough to design our duct system adaptively. Therefore, using 3-D CFD analysis we obtained the pressure loss coefficient for our duct models and chose the appropriate bending or diving duct type. In this paper, we used the CFD-ACE+ software package for the CFD analysis and the modeling of duct system. Through the 3-D CFD analysis, we investigated also the pressure loss and the velocity distributions of the designed whole duct system as well as the blade duct. Comparing the 3-D CFD result with 1-D analysis result, we lessened the uncertainty of the designed duct system and speculated the problem that was not concerned in design state.