• Proceedings of the KSR Conference
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• 2002.05a
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• pp.486-491
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• 2002

As the European Union has strengthened and computerized signalling systems have been widely used, the European common standards for the safety of railway signalling systems such as EN 50126, EN 50128, ENV 50129, EN 50159 began to be published from 1996 in CENELEC. At that time, a safety guideline, 'Safety Guidelines for Computerized Train Control and Protection Systems' was published in Japan. The Korean National Railroad also published a safety recommendation for the train control systems with taking into account the Korean railway conditions. Now the preparations for IEC/TC9 Standards are well underway and these standards correspond to CENELEC Standards referred above. These movements and activities are to cope with many technical and operational changes and to reflect the globalization trend of railway sectors along with the computerization of signalling devices. In this connection, this paper studies the globaliztion trend in the safety standards for railway signalling systems and discusses the counterplans for the trend.

• Archives of Pharmacal Research
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• v.19 no.3
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• pp.248-250
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• 1996

In conclusion, a series of N-Cbz-.alpha.-amono-glutarimides (1a-f), combining common structures such as N-CO-C-N and cyclic imide in a single molecule, were prepared from the (R)- or (S)-N-Cbz-glutamic acid and evaluated for their anticonvulsant activities in MES and PTZ tests in order to develope new and broad spectrum anticonvulsant. In this study, N-Cbz-.alpha.-aminoglutarimides (1) except ac and af, showed significant anticonvulsant activity in both MES and PTZ tests enough to be recommended as promising new anticonvulsant drug candidates. Now we are continuing to investigate further anticonvulsant test (quantification)for these compounds and synthesize their analogues in order to develop more active anticonvulsant and define the structure activity relationship more precisely.

• Journal of Microbiology and Biotechnology
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• v.7 no.6
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• pp.373-377
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• 1997

The gene for isopenicillin N synthase (cyclase; IPNS) was cloned from Lysobacter lactamgenus using DNA probe amplified with primers based on the consensus sequences of isopenicillin N synthase genes of other ${\beta}$-lactam-producing microorganisms. The genomic library of L. lactamgenus using pUC18 plasmid cloned at the SacI site were screened with the PCR-generated DNA probe and three positive clones were isolated. Enzyme activities in E. coli clones were confirmed by bioassay and HPLC assay. Throughout the functional mapping, it was observed that the gene for isopenicillin N synthase is located at the 1.3-kb XhoI-BamHI fragment of insert of positive clones. Nucleotide sequencing at both ends of the XhoI-BamHI fragment revealed that IPNS of L. lactamgenus has the common amino acid sequences at amino- and carboxy-termini.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.525-528
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• 2006

South Korea has about 80 permanent GPS stations, being used for a variety of applications such as DGPS, RTK, survey and geodesy. Some of them are installed in or near the coastal area for the purpose of maritime navigation. But, until recently, none of them are used for tide gauge benchmark monitoring. In order to monitor the absolute sea level changes, it is necessary to monitor the land uplift or subsidence occurring at tide gauge sites. It is a common practice to use GPS stations installed at tide gauges to determine absolute sea level. This collaborative efforts coordinated by IGS are called TIGA Pilot Project. Many countries including U.S., Canada, European Union nations, Australia and Japan are participating in TIGA, but South Korea is not a member yet. Recently, we established continuously operating GPS stations at tide gauges located in Incheon and Jeju to monitor the movement of tide gauges sites. This paper will introduce goals and progress of the efforts.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.837-839
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• 2003

Low spatial resolution remote sensing (RS) data (LSRD) are promising in agricultural monitoring activities due to their high temporal resolution, but under such a spatial resolution, mixing in a pixel is a common problem. In this study, a numerical experiment was conducted to explore a mixed pixel problem in agriculture using a combined RSsimulation model SWAP (Soil-Water-Atmosphere -Plant) and a Genetic Algorithm (GA) approach. Results of the experiments showed that it is highly possible to address the mixed pixel problem with LSRD.

• Nuclear Engineering and Technology
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• v.48 no.2
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• pp.470-481
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• 2016

Field-programmable gate arrays (FPGAs) have received much attention from the nuclear industry as an alternative platform to programmable logic controllers for digital instrumentation and control. The software aspect of FPGA development consists of several steps of synthesis and refinement, and also requires verification activities, such as simulations that are performed individually at each step. This study proposed an integrated software-testing framework for simulating all artifacts of the FPGA software development simultaneously and evaluating whether all artifacts work correctly using common oracle programs. This method also generates a massive number of meaningful simulation scenarios that reflect reactor shutdown logics. The experiment, which was performed on two FPGA software implementations, showed that it can dramatically save both time and costs.

• Proceedings of the Membrane Society of Korea Conference
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• 1998.10a
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• pp.150-152
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• 1998

Now the lack of water is serious problem all over the world because of the growth of population and expansion of industrial activities. So wastewater recycle and reuse is essential in many countries. One of the most popular wastewater treatment processes is conventional activated sludge system. In spite of significant degree of treatment rate the biological process has some operational difficulties and capital disadvantages. In conventional activated sludge process, sludge settling condition is getting worse in case of sludge bulking, it is common that overall process fails due to wash-out of biomass causing low concentration of MLSS in the aeration tank. Because of the absence of claifier the membrane bioreactor(MBR) process is less affected by such problems.

• Proceedings of the Technology Innovation Conference
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• 2002.02a
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• pp.183-203
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• 2002

The governments investment in R&D has rapidly increased so that a comprehensive and coherent approach to resource allocation has necessitated. Therefore the need for priorities in science and technology has been increased according to growing resources to science and technology. This study presents the methodology, process and results of priority-setting of national strategic technologies(IT, BT, NT, ST, ET, CT) through which 77 national key technologies are selected based on the criteria. Specifically it is intended to identify strategically necessary areas of focus for R&D, help leverage limited resources most effectively, and help coordinate government R&D activities by supplying ministries with a common set of priorities.

• Preventive Nutrition and Food Science
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• v.2 no.2
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• pp.155-161
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• 1997

The mutagenic and antimutagenic activities of juices from 20 common edible wild herbs found in Korea were investigated using the spore-rec assay and Ames test. The juices of Hemerocallis fulva and Capsella bursapastoris exhibited a little induction or inhibition of mutagenesis in the presence of selected metal ions, but juices of most edible wild herbs did not affect on the mutagenesis in the spore-rec assay. In the other hand, all of the juices strongly inhibited the mutagenesis induced by benzo[a]pyrene, 2-amino-fluorene, and 3-amino-1,4-dimethyl-5H-pyridol tested on Salmonella typhimurium TA98 or TA100 in the presence of S-9 mix. The antimutagenic effects increased as the concentration of the mutagens increase. The results suggest that concentration of samples or types of various mutagen interact to affect the antimutagenic potential of the juices in the TA98 and TA100 strain.

• Safety and Health at Work
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• v.1 no.1
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• pp.11-18
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• 2010

In the UK, a person or organisation that creates risk is required to manage and control that risk so that it is reduced 'So Far As Is Reasonably Practicable (SFAIRP).' How the risk is managed is to be determined by those who create the risk. They have a duty to demonstrate that they have taken action to ensure all risk is reduced SFAIRP and must have documentary evidence, for example a risk assessment or safety case, to prove that they manage the risks their activities create. The UK Health and Safety Executive (HSE) does not tell organisations how to manage the risks they create but does inspect the quality of risk identification and management. This paper gives a brief overview of where responsibility for occupational health and safety lies in the UK, and how risk should be managed through risk assessment. The focus of the paper is three recent major UK incidents, all involving fatalities, and all of which were wholly avoidable if risks had been properly assessed and managed. The paper concludes with an analysis of the common failings of risk assessments and key actions for improvement.