• Title/Summary/Keyword: Commentary

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What is a Cancer Cell? Why does it Metastasize?

  • Hegde, Mahabaleshwar Vishnu;Mali, Aniket Vijay;Chandorkar, Shubha Sandeep
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3987-3989
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    • 2013
  • This is a commentary on what a cancer cell is and why cancer cells metastasize. Normal cell get transformed to a cancer cell, with excessive production of free radicals that mutate the DNA of a normal cell. The immortality and malignant stage of transformed cell is maintained by higher GSH levels. With the faster rate of proliferation, when the cancer cell finds the place of origin is not conducive to its further growth, cancer cell chooses to take the metastatic course. We argue that if we can stop the exit of cancer cell from place of origin, cancer spread can be stopped or even cured.

Developing connection design rules in China

  • Shi, Yongjiu
    • Steel and Composite Structures
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    • v.5 no.2_3
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    • pp.141-158
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    • 2005
  • The new version of Code for Design of Steel Structures (GB50017-2003) and other design standards in China were released over the last two years. Comparing with the previous version (GBJ17-88), many clauses covering the connection design have been revised. A number of additional provisions are supplemented to specify the design requirements for beam-column moment connections, as well as gusset plates for truss joints. In this paper, a summary on the design rules on connections specified in the current Chinese code is presented, and relevant commentary and background information is provided whenever appropriate. The design criteria governing weld and bolt resistance is examined and reviewed. Moreover, several issues such as detailing requirements for stiffeners and end-plate connections are discussed.

Nature에 게재된 최근 식품관련 문헌 분석

  • Jang, Dae-Ja;Yang, Hye-Jeong
    • Bulletin of Food Technology
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    • v.16 no.2
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    • pp.78-179
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    • 2003
  • Nature 본지는 1896년에 창간된 이래 130년 이상 과학출판에 있어 지대한 영향력을 끼쳐온 과학잡지로 최근 Nature 본지 이외에도 자매지인 Nature Biotechnology(1983년 창간), Nature Cell Biology(1999), Nature Genetics(1992), Nature Meterials(2002), Nature Immunology(1999), Nature Medicine(1995), Nature Neuroscience(1998), Nature Structural Biology(1994)의 8개의 Nature Reserch Journal이 있으며 6개의 Nature Reviews(Nature Reviews Cancer, Nature Reviews Drug Discovery, Nature Reviews Genetics, Nature Reviews Immunology, Nature Reviews Molecular Cell Biology, Nature Reviews Neuroscience)가 있다. Nature 본지는 Editorials, News, News Feature, Correspondence, Commentary, Books and Arts, Concepts, News and Views, Brief Communications, Review Article, Articles, Letter to Nature, Naturejob 등으로 구성된 주간지로 과학전반에 걸친 중요한 성과를 즉각적으로 출판할 기회 뿐 아니라 과학에 관한 뉴스나 이슈 등에 대한 토론의 장을 제공하기도 한다. Nature 본지의 2002년 ISI impact factor는 30.432로 SCI에 등재된 저널중에서 매우 높은 수위를 차지하고 있다. 따라서 Nature 본지에 게재된 식품 및 유관 분야에 대한 조사 분석 결과를 게재하오니 향후 투고 방향 설정에 참고하시기 바랍니다. 식품기술에서는 계속적으로 update할 예정입니다.

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The Image of Nursing projected in Newspapers (신문에 나타난 간호의 이미지에 관한 연구)

  • 정면숙;강영실
    • Journal of Korean Academy of Nursing
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    • v.23 no.1
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    • pp.16-28
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    • 1993
  • The purpose of this study was to identify the im-. age of nursing, that is, to see how nursing is viewed in newspapers. Articles about nursing from two Korean daily newspapers from Jan. 1, 1987 to Dec.31, 1991 were examined for subject, type, attitude and author-ship. The inter-rater reliability was 0.89(by The Holsti method). The major findings were as follows : 1. The total number of articles were 110. 2. As for the subjests matter, articles related to professional nursing activities appeared most frequently(29.6%) , there about labor issues and activity to promote nurses's job climate 19.4%, and about official activities of nursing 11.2%. 3. Commentary articles appeared most frequently(41.2%) , Other article forms were straight news(27. 1%), contribution(17.6%) and inter-views (10.6%). 4. Feature stories acounted for 62.4% and news articles for 37.6%. Most of the articles were of national interests(96.5%), the rest(3.5%) of news from abroad. 5. Articles favorable toward nursing accounted for 54.1%, neutral 28.2%, negative 17.6%. 6. Many articles were written by the reporters (66.3%).

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Necessity of Establishment of Standards and Commentary for Laboratory Soil Tests by KGS (실내 토질시험에 대한 학회기준 제정 및 해설서 발간의 필요성)

  • Shin, Dong-Hoon;Kim, Ki-Young;Im, Eun-Sang;Park, Han-Gyu
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.656-662
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    • 2008
  • 1990년대 중반 이후 다양하고 많은 지반조사 및 실내시험 기술이 도입되어 사용되고 있고, 이제는 상당한 경험과 데이터가 축적되고 있음에도 불구하고 우리나라 또는 우리 지반공학회와 같은 학회 차원의 조사 및 시험 기준 정립이 미흡한 실정이다. 이에 본 논문에서는 국가 차원에서 이미 제정되어 있는 지반공학 관련 조사 및 시험 기준을 선진외국의 기준 현황과 비교검토하여 우리의 현주소를 살펴보았다. 또한, 최근 건설제도의 변화와 사회 전반의 기술발전에 따라 지난 10여년간 다양하고 활발하게 시도되고 있는 실내 토질시험 실시현황 등을 살펴보고 이들에 대한 기준의 추가 제정과 해설집 발간의 필요성을 제기하였다.

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Association Between Green Tea Consumption and Lung Cancer Risk

  • Lee, Andy H.;Liang, Wenbin;Hirayama, Fumi;Binns, Colin W.
    • Journal of Preventive Medicine and Public Health
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    • v.43 no.4
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    • pp.366-367
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    • 2010
  • Green tea is a popular beverage and its health benefits are well known. However, inconsistent results have been reported in observational studies concerning the association between green tea consumption and the lung cancer risk. In this commentary, several methodological issues underlying the measurement of tea exposure are highlighted. The recommendations should be useful for designing and planning prospective cohort studies to ascertain the protective effect of green tea against lung cancer.

Drugs from Marine Sources: Modulation of TRAIL Induced Apoptosis in Cancer Cells

  • Farooqi, Ammad Ahmad;Attar, Rukset;Gasparri, Maria Luisa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.9045-9047
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    • 2014
  • There have been overwhelming advances in molecular oncology and data obtained through high-throughput technologies have started to shed light on wide ranging molecular mechanisms that underpin cancer progression. Increasingly it is being realized that marine micro-organisms and the biodiversity of plankton are rich sources of various anticancer compounds. Marine derived compounds play major roles in inducing apoptosis in cancer cells. More importantly, various agents have been noted to enhance TRAIL induced apoptosis in cancer cells by functionalizing intrinsic and extrinsic pathways. In this commentary, a list of marine derived compounds reported to induce apoptosis is discussed.

Impact of Enhanced Recovery Program on Colorectal Cancer Surgery

  • Lohsiriwat, Varut
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3825-3828
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    • 2014
  • Surgical outcomes of colorectal cancer treatment depend not only on good surgery and tumor biology but also on an optimal perioperative care. The enhanced recovery program (ERP) - a multidisciplinary and multimodal approach, or so called 'fast-track surgery' - has been designed to minimize perioperative and intraoperative stress responses, and to support the recovery of organ function aiming to help patients getting better sooner after surgery. Compared with conventional postoperative care, the enhanced recovery program results in quicker patient recovery, shorter length of hospital stay, faster recovery of gastrointestinal function, and a lower incidence of postoperative complications. Although not firmly established as yet, the enhanced recovery program after surgery could be of oncological benefit in colorectal cancer patients because it can enhance recovery, maintain integrity of the postoperative immune system, increase feasibility of postoperative chemotherapy, and shorten the time interval from surgery to chemotherapy. This commentary summarizes short-term outcomes and potential long-term benefits of enhanced recovery programs in the treatment of colorectal cancer.

Importance of Meta-Analysis and Practical Obstacles in Oncological and Epidemiological Studies: Statistics Very Close but Also Far!

  • Tanriverdi, Ozgur;Yeniceri, Nese
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1303-1306
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    • 2015
  • Studies of epidemiological and prognostic factors are very important for oncology practice. There is a rapidly increasing amount of research and resultant knowledge in the scientific literature. This means that health professionals have major challenges in accessing relevant information and they increasingly require best available evidence to make their clinical decisions. Meta-analyses of prognostic and other epidemiological factors are very practical statistical approaches to define clinically important parameters. However, they also feature many obstacles in terms of data collection, standardization of results from multiple centers, bias, and commentary for intepretation. In this paper, the obstacles of meta-analysis are briefly reviewed, and potential problems with this statistical method are discussed.

Understanding of the Sameum-Samyang in "Dong-uisusebowon(東醫壽世保元)" ("동의수세보원(東醫壽世保元)"의 삼음삼양(三陰三陽) 인식(認識))

  • Jang, Woo-Chang
    • Journal of Korean Medical classics
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    • v.23 no.1
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    • pp.303-316
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    • 2010
  • Ijema's four constitution theory is the result of creative succession which is originated from the "Hwangjenaegyeong(黃帝內經)", and shaped up as "Sanghanron(傷寒論)", the key of Ijema's theory would be the re-explnation of the Sameum-Samyang pattern identification. therefore, we should recognize that the four constitution theory is related to the Sameum-Samyang identification of "Sanghanron(傷寒論)". And is even on the mutual supporting relation. from this point of view, the "Dong-uisusebowon(東醫壽世保元)" could be valuated as a commentary of "Sanghanron(傷寒論)" which shows us that how to review the Sameum-Samyang identification as the point of characteristic of four constitution theory.