• The Journal of Korean Medicine
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• v.45 no.2
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• pp.41-54
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• 2024

Objectives: Cannabis root is a medicinal plant that has been used in traditional medicine around the world. However, in previous studies using simple extracts, the biological activity was not relatively prominent compared to other herbal medicines. The aim of the present study is to confirm the enhancement of anti-inflammatory activity and bioactive compound of Cannabis root extract prepared by combined processing process. Methods: A series of processes including repeated steam and dry, fermentation, hydrothermal extraction and ethanol extraction was applied to Cannabis root. The antioxidant content of cannabis root extracts obtained through a combined processing process was investigated by analyzing the total phenolic, tannin, and flavonoid contents. Anti-inflammatory effects were tested in LPS-treated RAW264.7 cells. The anti-inflammatory mechanism was examined by western blot. Finally, the component profile of Cannabis root extract was analyzed using High Performance Liquid Chromatography (HPLC) and Thin layer chromatography (TLC). Results: The cannabis root extract prepared by complex processing process had higher antioxidant and anti-inflammatory effects than simple extract. Total phenolic and tannin contents were significantly increased, and DPPH free radical inhibition activity was strengthened by combined processing process. Increased NO production and iNOS expression in LPS-treated RAW264.7 cells were decreased in a concentration-dependent manner upon extract treatment by complex processing process. Additionally, the Stigmasterol content of Cannabis root extract was increased through a complex processing process. Conclusions: Further research is needed on the mechanisms and substances that exhibit the anti-inflammatory effects of Cannabis roots extract prepared by complex processing process.

• Transactions of Materials Processing
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• v.18 no.7
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• pp.538-543
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• 2009

The cowl cross bar of an automobile is a frame component that is installed inside the cockpit module to provide a guide surface, to which functional components for electricity and air condition are attached. In the recent years, the geometries of cowl cross bars are getting more complex in order to meet the demands of a wide variety of embedded functional components and the reduced weight of frame parts with enhanced mechanical and noise/vibration characteristics. There for, welding processes between tubes with different diameters are widely conducted while the welded parts are experiencing various problems such as undermined appearance, low production efficiency and poor mechanical characteristics. Therefore, this paper seeks to develop an one-piece forming process which eliminate welding process for the cowl cross bar by applying the tube drawing process. However, it was predicted that a conventional tube drawing can not be applied directly to the current part since the area reduction ratio of the drawing process reaches 51.7% which exceeds the general limiting value. Therefore, in this study, a combined drawing process which adds a compressive force to a tensile force of the conventional drawing process was proposed and 2-stage drawing process was designed by using CAE analyses. In addition, drawing tryouts were carried out by using the manufactured combined drawing machine in order to verify the designed process.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.5
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• pp.623-629
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• 2004

In this paper, a Efficient method for the mixed image separation is presented using independent component analysis and the new fast expectation-maximization(EM) algorithm. In general, the independent component analysis (ICA) is one of the widely used statistical signal processing scheme in various applications. However, it has been known that ICA does not establish good performance in source separation by itself. So, Innovation process which is one of the methods that were employed in image separation using ICA, which produces improved the mixed image separation. Unfortunately, the innovation process needs long processing time compared with ICA or EM. Thus, in order to overcome this limitation, we proposed new method which combined ICA with the New fast EM algorithm instead of using the innovation process. Proposed method improves the performance and reduces the total processing time for the Image separation. We compared our proposed method with ICA combined with innovation process. The experimental results show the effectiveness of the proposed method by applying it to image separation problems.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2000.04a
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• pp.507-512
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• 2000

Due to increasing demand toward improving product quality, various methodologies have been introduced. A brush type grinding tool is one of the most frequently used one to facilitate required process. In order to produce consistent burr shape, various machining conditions have been combined applied to disk grinding process. It has been observed that the burr dimension(shape and width) depends on the inclination angle between grinding disk and workpiece. Drastic increase of tool Wear has been also observed along the inclination angle variation. Various burr shapes have been captured and analyzed using image processing technique.

• Laser Solutions
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• v.5 no.3
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• pp.15-20
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• 2002

The principal obstacle to selection of a laser processing method in production is its relatively high equipment cost and the natural unwillingness of production supervision to try something new until it is thoroughly proven. The major objective of this work is focused on the combined features of gas tungsten arc and a low-power cold laser beam. In this work, the laser beam from a 7 watts carbon monoxide laser was combined with electrical discharges from a short-pulsed capacitive discharge GTA welding power supply. When the low power CO laser beam passes through a special composition shielding gas, the CO molecules in the gas absorbs the radiation, and ionizes through a process blown as non-equilibrium, vibration-vibration pumping. The resulting laser-induced plasma(LIP) was positioned between various configurations of electrodes. The high-voltage impulse applied to the electrodes forced rapid electrical breakdown between the electrodes. Electrical discharges between tungsten electrodes and aluminum sheet specimens followed the ionized path provided by LIP. The result was well-focused melted spots.

• Transactions of Materials Processing
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• v.14 no.5 s.77
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• pp.439-443
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• 2005

Deep drawing and cold forging processes are combined to achieve near net shape forming of automotive part which has not only drum shape but also thickness variation. It is important to find out proper intermediate shape where two totally different forming methods should be joined seamlessly. In the course of development of the combined process, finite element analysis can be utilized effectively to decide optimal position for transferring from the sheet metal work to the bulk forming. Because machining process is eliminated, significant improvement in integrity, reliability, and durability of the part is expected. The developed process combination could be applied in real manufacturing process successfully.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.3
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• pp.394-400
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• 2012

Due to the increasing demand for carious methodologies, the quality improvement of products were introduced. A brush, the most frequently used type of grinding process, is one of the deburring. In order to produce consistent burr shape, various machining conditions have been combined and applied to disk grinding process. By tool dynamometer, acoustic emission sensor and acceleration sensor depend on changes in processing conditions(depth of engagement, cutting speed, workpiece position, workpiece orientation, cutting time) signals were obtained for brush deburring grinding system. Root mean square obtained by processing the signal processing conditions by analyzing the characteristics of deburring is to derive the optimum conditions.

• Transactions of Materials Processing
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• v.6 no.5
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• pp.446-455
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• 1997

A Combined extrusion operation consists of forward and backward extrusion forming and it is possible to make the process be simple by employing it. But the metal flow pattern induced by the operation is hard to analyze accurately because the flows are non-steady, which have at least two directions dependent upon each other. So engineers in the industrial factories had conducted the two extrusion operations separately. A new process was designed by the industrial expert for forming of an alu-minum preform using the combined extrusion operation. In this study, experiments and finite element analysis was carried out to determine the process parameters. Through the preliminary experiment, it was shown that warm forming condition was more desirable than cold or hot ones. And optimal shape of initial billet could be also determined. From the compatibility test, bonde-lube was chosen as the optimal lubricant and 20$0^{\circ}C$ as the material temperature by the inspection of micro-structure. The operation was simulated by the rigid-plastic finite element method to examine the metal flow. Disap-pearing of dead metal zone was observed as the punch fell down and desirable shape was obtained from the one operation. As a result of this study, 7 operations could be reduced and 225% of material saved.

• Transactions of Materials Processing
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• v.17 no.2
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• pp.102-106
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• 2008

Cryogenic rolling combined with warm rolling has been found more effective than a single cryogenic rolling process in improving the strength of a 5052 Al alloy. In this study, cryo-rolled 5052 Al alloys were warm-rolled at $175^{\circ}C$. A notable increase of tensile strength was achieved by the precipitation during warm rolling process. Mechanical behavior of this alloy was investigated using hardness and tensile tests. It was found that the cryogenic rolling process combined with warm rolling process was very effective in improving tensile strength.

• Transactions of Materials Processing
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• v.11 no.1
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• pp.45-53
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• 2002

The forming process of metal matrix composites by die casting and squeeze casting process are limited in size and dimension In term of final parts. The melt strirring method have the problems that the homogeneous distribution of the reinforcements is difficult due to the low weldability and the density difference between the molten metal and the reinforcement. The thixoforming process for metal matrix composites has numerous advantages compacted to die casting, squeeze casting and compocasting. However, for the thixofoming process, the billet with the desired volume fraction must be heated to obtain a uniform temperature distribution over the entire cross-sectional areas. To obtain the reheating conditions of composites, the particulate reinforced metal matrix composites for thixoforming were fabricated by combined stirring process which is simultaneously performed with electro-magnetic stirring and mechanical stirring process. The matrix alloy and reinforcement are used to aluminum alloy(A357) and SiCp with diameter 14, $25{\mu}m$, respectively. The microstructure characteristics were investigated by changing the volume fraction and reinforcement size. The heating conditions to obtain the uniform temperature distribution in cross section area of fabricated metal matrix composites billet are proposed with heating time, the heating temperature and the holding time.