• Proceedings of the PSK Conference
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• 2003.10b
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• pp.188.3-189
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• 2003

Nonsteriodal antiinflammatory drugs(NSAIDs) are widely used to treat pain, fever, and inflammatory conditions including osteoarthritis. But chronic patients suffer from gastrointestinal disturbances such as discomfort, nausea, peptic ulcer and severe bleeding because NSAIDs inhibit not only COX-2 associated with anti-inflammatory activity, but also COX-l accompanied with side effects in the stomach and kidney. Therefore, in this study, we designed a new 2-thiohydantoin derivatives as selective COX-2 inhibitors is that the 5-membered heterocycle ring is substituted with two aryl groups. (omitted)

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.204.2-205
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• 2000

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.215.2-215.2
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• 2000

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.186.1-186.1
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• 2002

• Korean Journal of Clinical Pharmacy
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• v.33 no.3
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• pp.153-167
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• 2023

Objective: Bipolar disorder displays a spectrum of manifestations, including manic, hypomanic, depressive, mixed, psychotic, and atypical episodes, contributing to its chronic nature and association with heightened suicide risk. Creating effective pharmacotherapy guidelines is crucial for managing bipolar disorder and reducing its prevalence. Treatment algorithms grounded in science have improved symptom management, but variations in recommended medications arise from research differences, healthcare policies, and cultural nuances globally. Methods: This study compares Korea's bipolar disorder treatment algorithm with guidelines from the UK, Australia, and an international association. The aim is to uncover disparities in key recommended medications and their underlying factors. Differences in CYP450 genotypes affecting drug metabolism contribute to distinct recommended medications. Variances also stem from diverse guideline development approaches-expert consensus versus metaanalysis results-forming the primary differences between Korea and other countries. Results: Discrepancies remain in international guidelines relying on meta-analyses due to timing and utilized studies. Drug approval speeds further impact medication selection. However, limited high-quality research results are the main cause of guideline variations, hampering consistent treatment conclusions. Conclusion: Korea's unique Delphi-based treatment algorithm stands out. To improve evidence-based recommendations, large-scale studies assessing bipolar disorder treatments for the Korean population are necessary. This foundation will ensure future recommendations are rooted in scientific evidence.

• Obstetrics & gynecology science
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• v.61 no.6
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• pp.662-668
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• 2018

Objective This study was to identify the risk factors for cytological progression in women with atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL). Methods We analyzed data from women infected with the human papillomavirus (HPV) who participated in the Korean HPV cohort study. The cohort recruited women aged 20-60 years with abnormal cervical cytology (ASC-US or LSIL) from April 2010. All women were followed-up at every 6-month intervals with cervical cytology and HPV DNA testing. Results Of the 1,158 women included, 654 (56.5%) and 504 (43.5%) women showed ASC-US and LSIL, respectively. At the time of enrollment, 143 women tested positive for HPV 16 (85 single and 58 multiple infections). Cervical cytology performed in the HPV 16-positive women showed progression in 27%, no change in 23%, and regression in 50% of the women at the six-month follow-up. The progression rate associated with HPV 16 infection was higher than that with infection caused by other HPV types (relative risk [RR], 1.75; 95% confidence interval [CI], 1.08-2.84; P=0.028). The cytological progression rate in women with persistent HPV 16 infection was higher than that in women with incidental or cleared infections (P<0.001). Logistic regression analysis showed a significant relationship between cigarette smoking and cytological progression (RR, 4.15; 95% CI, 1.01-17.00). Conclusion The cytological progression rate in HPV 16-positive women with ASC-US or LSIL is higher than that in women infected with other HPV types. Additionally, cigarette smoking may play a role in cytological progression.

• The Korean Journal of Food And Nutrition
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• v.4 no.1
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• pp.35-44
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• 1991

This survey was carried out to Investigate the effect of the daily average nutrient intakes, self-consciousness of nutrition knowledge and health on the nutrition knowledge and food habits between college women and their own mothers, Questionnaires were completed by 214 college women who do major in nutrition and by 173 their mothers. The college women scored significantly higher than that of their mothers In the nutrition knowledge. And their mothers scored significantly higher than that of college women in the food habits. Most of the subjects belonged to 'Fair' food habit group, which was considered to be relatively good. The correlation of the scores between nutrition knowledge and food habits of the college women and their mothers was low. The daily average nutrient Intakes of all women were higher than the recommended dietary allowance except for that of Iron. There was a significant and negative correlation between the nutrition knowledge score and daily average nutrient intakes in college women. But there was not a significant correlation in the nutrient intakes in their mothers. And also there was a significant and positive correlation between food habits score in their mothers but there was not a significant correlation score in college women. The higher the women had a self-consciousness of health, the higher their mothers had a food habit score, but they had daily average nutrient intakes were lower than their daughter's(college women), And the women that had a self-consciousness of health were healthier, daily nutrient intakes in their own mothers were higher in the food habits scores than that of the college women. The main curriculum for a good food habits is that it is important that one has a responsible nutrition education. For the improvement of nutrition education program we should transmit the nutritional information through an effective mass media(i. e. Radio, TV, Newspaper).

• Journal of Fashion Business
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• v.3 no.4
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• pp.131-138
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• 1999

The purpose of this study is to measure Korean, Chinese and Chosunjok college women's body part sizes, and then, classify their body shapes according to the drop value(hip circumference-chest circumference) as well as their statures, and thereupon, comparatively analyze the statistical distribution of their major body part measurements and thereby, provide for some basic data useful to the development of quality fitting apparels exportable to China. The results of this study can be summarized as follows; Most of Korean and Chinese college women were found to belong to the body type of "N" body shape, while many of Chosunjok college women belonged to "H" body shape body type characterized by normal stature but small difference between hip and chest circumferences. The most prevailing body type of Korean and Chinese college women next to "N" type(65%, 51%) was "H" (23%, 35%), followed by "A" type(12%, 14%), while that of Chosunjok college women was "H" type (54%), followed by "N" (40%) and "A" type (6%). On the other hand, in terms of distribution of major body part sizes, there was found a wide difference between Chinese and Korean college women. Chosunjok college women had similar body part sizes to Korean college women's in such measurements as waist back length, shoulder-to-shoulder length, front interscye length, back interscye length, under-chest circumference and weight, while having simliar body part sizes to Chinese college women's in such measures as stature, arm length, waist front length, waist side-hip line length, crotch length, head circumference, neck-root circumference and waist circumference.

• Journal of the Korea Fashion and Costume Design Association
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• v.13 no.4
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• pp.69-77
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• 2011

The purpose of this study was to identify the analysis of men's wear color preference between Korean and Chinese college women. The experimental materials developed for this study were a set of stimulus and response scales. The 24 color pictures and 5-point scales were used for evaluation of preference. Data were obtained from 120 Korean college women living in Kyeongnam, Korea and 120 Chinese college women living in Shandog, China on October and November 2010. For data analysis, ANOVA and Duncan-test were used by using SPSS program. Results of this study were as follows. Korean and Chinese college women, shirts hue, tie hue, and shirts/tie tone showed an independent effect on men's wear color preference. Interaction effects of Korean and Chinese college women and shirts hue, Korean and Chinese college women and tie hue, suit hue and shirts hue, shirts hue and shirts/tie tone, and tie hue and shirts/tie tone were found. These results suggested that men's wear color preference can be affected by Korean and Chinese college women, suit hue, shirts hue, tie hue, and shirts/tie tone.

• 대한생식의학회:학술대회논문집
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• 2007.06a
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• pp.147-147
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• 2007