• Korean Journal of Community Nutrition
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• v.15 no.4
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• pp.513-524
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• 2010

This study was designed to examine nutrition label use, self-efficacy, snacking and eating behaviors of middle school students, and to investigate if these characteristics were different by nutrition label use. A cross-sectional survey was conducted to 348 middle school students in Kyunggi, Korea. About a third of subjects read nutrition labels when they purchased snacks/packaged foods. Most nutrition label users were interested in reading information on calories, fat and trans-fat. Self-efficacy of eating/selecting snacks or general nutrition behavior was moderate (mean score: 44.4 out of 60), with significantly higher score in nutrition label users compared to nonusers (p < 0.001). Nutrition label users felt more confident in 9 items out of 15 items of self-efficacy, such as "taking fruits instead of cookies/candy for snack" (p < 0.001), "choosing milk instead of soft drink" (p < 0.01), "not having snacks after dinner" and "avoiding processed foods for snacks" (p < 0.05). Subjects had snacks 1.3 times a day, and nutrition label nonusers consumed snacks more frequently than the counterparts (p < 0.01). About 55% of nutrition label users and 64.7% of nonusers mainly purchased snacks for themselves (p < 0.05). Commonly purchased snacks by adolescents were ice cream, cookies/chips, breads and ramen. Major considerations in purchasing snacks were taste (46.9%) and price (34.6%). In selecting snacks, the influence of friends and parents was greater than the other sources. Based on eating frequency of snacks, nutrition label users were more likely to consume healthy snacks, such as fruit juices, vegetables, milk, yogurt, and potato/sweet potato than nonusers (p < 0.05). Eating behaviors measured by 15 items scored 33.6 out of 45. Nutrition label users showed better eating behaviors, such as "eating meals slowly", "eating foods cooked with plant oil", and "eating out less frequently" (p < 0.05). Study results showed that majority of adolescents did not read nutrition labels, selected snacks for themselves and had somewhat unhealthy foods for snacks. This study also showed the differences in self-efficacy, snacking and eating behaviors between nutrition label users and nonusers. In nutrition education, it is necessary to stress the importance and skills for reading nutrition labels. It is also needed to help adolescents to select healthy snacks and have desirable eating behaviors, as well as increasing self-efficacy.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.1
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• pp.29-39
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• 2006

Statements of problem: Zirconia core is used for posterior fixed partial dentures because it's good mechanical properties. Stress is concentrated on connectors in fixed partial dentures, so the proper design of connector areas is needed for adequate mechanical long-term properties of any prosthesis. The area of connector is critical, but tooth size and surrounding soft tissue limit the connector design. Purpose: The purpose of this study is to compare fracture strengths between different connector designs of zirconia core for posterior fixed partial dentures manufactured with CAD/CAM system and determining the optimal connector design satisfying strength and hygiene. Material and method: The following four groups of 40 posterior fixed partial denture specimens(each group 10) were fabricated as followed; group 1 vertical height of connector is 3mm (control group, all groups have the same condition); group 2, lingual vertical 1mm reinforcement on connector; group 3, lingual vertical 2mm reinforcing on connector and group 4, lingual vertical 3mm reinforcing on connector. Specimens were subjected to compressive loading on the central fossa of pontic by instron. SEM was used to identify the initial crack and characterize the fracture mode. Results: The results were as follows: 1. The mean fracture load of the non-lingual reinforcing group was 1212N and the lingual vertical 1mm reinforcing group was 1510N, the lingual vertical 2mm reinforcing group was 1882N, the lingual vertical 3mm reinforcing group was 1980N. 2. The reinforcing groups were statistically significant compared to non-reinforcing groups(P<0.001). 3. There were 2, 3mm reinforcing groups that were statistically significant compared to 1mm reinforcing groups(P<0.001), and the 3mm reinforcing group was not statistically significant compared to 2mm reinforcing groups(P>0.05) 4. Fractures were initiated in gingival embrasures of connectors and processed to the loading site. Conclusion: In this study, lingual reinforcement of connector for improved strength of zirconia based fixed partial denture is nessasary. And long-term study for clinical application is required

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.1
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• pp.436-444
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• 2013

This article presents the dynamic response of nano-scale plates using the nonlocal continuum theory and higher-order shear deformation theory. The nonlocal elasticity of Eringen has ability to capture the small scale effects and the higher-order shear deformation theory has ability to capture the quadratic variation of shear strain and consequently shear stress through the plate thickness. The solutions of transient dynamic analysis of nano-scale plate are presented using these theories to illustrate the effect of nonlocal theory on dynamic response of the nano-scale plates. The relations between nonlocal and local theories are discussed by numerical results. Also, the effects of nonlocal parameters, aspect ratio, side-to-thickness ratio, size of nano-scale plate and time step on dynamic response are investigated and discussed. The amplitude and cycle increase when nonlocal parameter increase. In order to validate the present solutions, the reference solutions are used and discussed. The theoretical development as well as numerical solutions presented herein should serve as reference for nonlocal theories as applied to the transient dynamic analysis of nano-scale structures.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.116-122
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• 2021

This study quantitatively evaluated the performance improvement of a circular reinforced concrete pier under dynamic load with strengthening using a steel plate. Various three-dimensional elements were applied using the finite element program ABAQUS. The analytical parameters included the ratios of the steel cover length to the pier's total height and the ratios of the steel cover thickness to the pier diameter for inelastic-nonlinear analysis. The lower part of the pier had fixed boundary conditions, and lateral repetitive loads were applied at the top of the pier. The pier was investigated to evaluate the dynamic performance based on the load-displacement curve, stress-strain curve, ductility, energy absorption capability, and energy ratio. The yield and ultimate loads of piers with steel covers increased by 3.76 times, and the energy absorption capability increased by 4 times due to the confinement effects caused by the steel plate. A plastic hinge part of the column with a steel plate improved the ductility, and the thicker the steel plate was, the greater the energy absorption capacity. This study shows that the reinforced pier should be improved in terms of the seismic performance.

• Ecology and Resilient Infrastructure
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• v.9 no.2
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• pp.107-112
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• 2022

This study was conducted to investigate the effects of mulching materials in extensive green roof system by comparing and analyzing the soil moisture content and growth response of Lychnis cognata according to the types of organic mulching materials. The experimental group consisted of a control group that did not use mulching material (Cont.) and a total of five treatment groups, including cocochip (C.O), woodchip (W.O), straw (S.T), and sawdust (S.A), depending on the mulching material. The soil moisture content according to the type of organic mulching material was high in the order of W.O > S.T > Cont. > C.O > S.A, and there was a significant difference especially in S.A. The plant height showed good growth in the order of S.T > Cont. > C.O > W.O > S.A, and there was no significant difference by mulching materials in other growth items except for plant height. Both the chlorophyll and plant water contents were superior to those of untreated group, so the treatment of organic mulching materials is considered to be effective in maintaining the chlorophyll and plant water contents of Lychnis cognata. In particular, the soil moisture content was affected by the characteristics of the mulching material itself. Based on these results, it is required to use a mulching material suitable for the characteristics of each plant in extensive green roof system and it is considered that this can be overcome through organic mulching when selecting a plant species that is weak to water stress.

• Biomolecules & Therapeutics
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• v.31 no.2
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• pp.227-239
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• 2023

Major depressive disorder is a leading cause of disability in more than 280 million people worldwide. Monoamine-based antidepressants are currently used to treat depression, but delays in treatment effects and lack of responses are major reasons for the need to develop faster and more efficient antidepressants. Studies show that ketamine (KET), a PCP analog, produces antidepressant effects within a few hours of administration that lasts up to a week. However, the use of KET has raised concerns about side effects, as well as the risk of abuse. 4 -F-PCP analog is a novel PCP analog that is also an NMDA receptor antagonist, structurally similar to KET, and might potentially elicit similar antidepressant effects, however, there has been no study on this subject yet. Herein, we investigate whether 4-F-PCP displays antidepressant effects and explored their potential therapeutic mechanisms. 4-F-PCP at 3 and 10 mg/kg doses showed antidepressant-like effects and repeated treatments maintained its effects. Furthermore, treatment with 4-F-PCP rescued the decreased expression of proteins most likely involved in depression and synaptic plasticity. Changes in the excitatory amino acid transporters (EAAT2, EAAT3, EAAT4) were also seen following drug treatment. Lastly, we assessed the possible side effects of 4-F-PCP after long-term treatment (up to 21 days). Results show that 4-F-PCP at 3 mg/kg dose did not alter the cognitive function of mice. Overall, current findings provide significant implications for future research not only with PCP analogs but also on the next generation of different types of antidepressants.

• 한국노년학
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• v.25 no.2
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• pp.95-108
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• 2005

This study was done to explore the level of physiologic health status and health promotion lifestyle, and its contributing factors of Korean older adults. A total of 209 older adults participated in this study that ran from July 2 to July 6, 2004 in the waiting area of the subways of Seoul. The average age of the respondents was 67 years old with 39.2% considering themselves as healthy, 71.3% stating they regularly exercised and 71.8% knowing their own blood pressure. Among the participants 44% were classified as having high or low blood pressure and 44.5% showing abnormal blood sugar. The mean score of health promotion lifestyle was 2.75 and the order of its subcategories was interpersonal relationship, nutrition, stress management, spiritual growth, physical activities, and health responsibilities. This score was altered by exercise and knowing personal blood pressure. As a result of this study, it is important for older adults to know their own blood pressure and to exercise regularly to promote good health. In addition, health promotion programs should be developed and implemented based on the influencing factors.

• The Journal of Korean Academy of Prosthodontics
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• v.41 no.2
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• pp.182-206
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• 2003

Statement of problem : Successful osseointegration of endosseous threaded implants is dependent on many factors. These may include the surface characteristics and gross geometry of implants, the quality and quantity of bone where implants are placed, and the magnitude and direction of stress in functional occlusion. Therefore clinical quantitative measurement of primary stability at placement and functional state of implant may play a role in prediction of possible clinical symptoms and the renovation of implant geometry, types and surface characteristic according to each patients conditions. Ultimately, it may increase success rate of implants. Purpose : Many available non-invasive techniques used for the clinical measurement of implant stability and osseointegration include percussion, radiography, the $Periotest^{(R)}$, Dental Fine $Tester^{(R)}$ and so on. There is, however, relatively little research undertaken to standardize quantitative measurement of stability of implant and osseointegration due to the various clinical applications performed by each individual operator. Therefore, in order to develop non-invasive experimental method to measure stability of implant quantitatively, the resonance frequency analyzer to measure the natural frequency of specific substance was developed in the procedure of this study. Material & method : To test the stability of the resonance frequency analyzer developed in this study, following methods and materials were used : 1) In-vitro study: the implant was placed in both epoxy resin of which physical properties are similar to the bone stiffness of human and fresh cow rib bone specimen. Then the resonance frequency values of them were measured and analyzed. In an attempt to test the reliability of the data gathered with the resonance frequency analyzer, comparative analysis with the data from the Periotest was conducted. 2) In-vivo study: the implants were inserted into the tibiae of 10 New Zealand rabbits and the resonance frequency value of them with connected abutments at healing time are measured immediately after insertion and gauged every 4 weeks for 16 weeks. Results : Results from these studies were such as follows : The same length implants placed in Hot Melt showed the repetitive resonance frequency values. As the length of abutment increased, the resonance frequency value changed significantly (p<0.01). As the thickness of transducer increased in order of 0.5, 1.0 and 2.0 mm, the resonance frequency value significantly increased (p<0.05). The implants placed in PL-2 and epoxy resin with different exposure degree resulted in the increase of resonance frequency value as the exposure degree of implants and the length of abutment decreased. In comparative experiment based on physical properties, as the thickness of transducer increased, the resonance frequency value increased significantly(p<0.01). As the stiffness of substances where implants were placed increased, and the effective length of implants decreased, the resonance frequencies value increased significantly (p<0.05). In the experiment with cow rib bone specimen, the increase of the length of abutment resulted in significant difference between the results from resonance frequency analyzer and the $Periotest^{(R)}$. There was no difference with significant meaning in the comparison based on the direction of measurement between the resonance frequency value and the $Periotest^{(R)}$ value (p<0.05). In-vivo experiment resulted in repetitive patternes of resonance frequency. As the time elapsed, the resonance frequency value increased significantly with the exception of 4th and 8th week (p<0.05). Conclusion : The development of resonance frequency analyzer is an attempt to standardize the quantitative measurement of stability of implant and osseointegration and compensate for the reliability of data from other non-invasive measuring devices It is considered that further research is needed to improve the efficiency of clinical application of resonance frequency analyzer. In addition, further investigation is warranted on the standardized quantitative analysis of the stability of implant.

• Journal of Oral Medicine and Pain
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• v.30 no.4
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• pp.391-400
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• 2005

Special Practitioner exists based on the need for special fields that are required to manage difficult patients with specialized skills distinguished from General practitioner. The purpose of dental specialist system is to manage patients who are not treatable by general practitioner by training doctors specializing in one specific field, thereby, enhancing health of the public. Oral Medicine deals with orofacial pain, oral soft tissue disease, forensic dentistry, oral diagnosis. In these days, living environments of city life bring about increase in stress which ultimately lead to increase in prevalence of temporomandibular disorder, oral soft tissue disease, neuropathies such as trigeminal neuralgia, and hence, the number of patients seeking help of those symptoms tend to increase. The purpose of this study was to analyze the rate of referrals and the routes of patients seeking help by investigating 3,707 patients who visited Department of Oral Medicine, College of Dentistry, Yonsei University, from August, 2004 to April, 2005. The results were as follows: 1. The types of disease referred to the Department of Oral Medicine were orofacial pain, oral soft tissue disease, forensic dentistry, oral diagnosis. 2. The rate of referrals was 58.51% which implies that more than half of the patients visiting the Department of Oral Medicine were referred. 3. The types of institution which made referrals were analyzed, and as a result, dental clinics made most of the referrals with the rate of 83.23%, while that from medical or oriental medical institutions was 16.78%. 4. Among the patients who visited the Department of Oral Medicine on their own, 30.52% gained the information about the Department of Oral Medicine from internet and mass media, and from neighbors. From the above results, most of the patients visiting the Department of Oral Medicine were found to be referred not only from the field of dentistry but also from the field of medicine. These suggest that Oral Medicine manages patients who are not treatable by general dental practitioners, and medical specialists tend to cooperate with the Department of Oral Medicine to manage diseases associated with Oral Medicine. Therefore, the role of Oral Medicine can be considered to be important as a special field, and the results of this study should be considered when working out a policy of Dental specialist system on demand and supply of residents in the future.

• Journal of Life Science
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• v.29 no.2
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• pp.173-180
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• 2019

Amyloid ${\beta}$-protein ($A{\beta}$) is the principal component of senile plaques characteristic of Alzheimer's disease (AD) and elicits a toxic effect on neurons in vitro and in vivo. Many environmental factors, including antioxidants and proteoglycans, modify $A{\beta}$ toxicity. It is worthwhile to isolate novel natural compounds that could prove therapeutic for patients with AD without causing detrimental side effects. In this study, we investigated the in vitro neuroprotective effects of the ethyl acetate fraction of methanol extract of Ophiophogon japonicas (OJEA fraction). We used an MTT reduction assay to detect protective effects of the OJEA fraction on $A{\beta}_{25-35}$-induced cytotoxicity to PC12 cells. We also used a cell-based ${\beta}$-secretase assay system to investigate the inhibitory effect of the OJEA fraction on ${\beta}$-secretase activity. In addition, we performed an in vitro lipid peroxidation assay to evaluate the protective effect of the OJEA fraction against oxidative stress induced by $A{\beta}_{25-35}$ in PC12 cells. The OJEA fraction had strong protective effects against $A{\beta}_{25-35}$-induced cytotoxicity to PC12 cells and was strongly inhibitory to ${\beta}$-secretase activity, which resulted in the attenuation of $A{\beta}$ generation. In addition, the OJEA fraction significantly decreased malondialdehyde (MDA) content, which is induced by the exposure of PC12 cells to $A{\beta}_{25-35}$. Our results suggested that the OJEA fraction contained active compounds exhibiting a neuroprotective effect on $A{\beta}$ toxicity.