• Journal of Animal Reproduction and Biotechnology
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• v.37 no.1
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• pp.13-16
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• 2022

The use of animals heavily impacts the mental health of researchers performing the animal experiments. The animal researchers need to take care of animals but also give pain and sacrifice them at the same time. This circumstance can cause a variety of mental stress to the researchers. The stress generated in the laboratory would not only negatively affect the management of animals and the research results, but also would harm the researchers' physical and mental health. Because the feeling of sympathy for animals is a natural feature of humanity, psychological stress following a laboratory animal's death after use is not surprising. It is necessary to revise the relevant laws based on understanding the difficulties of animal researchers in society and to develop related educational programs at the national level to help the psychology and emotions of researchers who conduct animal experiments.

• Journal of Oriental Neuropsychiatry
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• v.8 no.1
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• pp.111-125
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• 1997

This study was done in order to investigate Oriental Medicine's meaning on stress, the stress is due to animal experiments.Methods:This research was done by animal experiments's results based on 41 animal experiment treatises carried out by 24 prescriptions about stress control. Each experiments were compared with same conditions, minimizing the experiments differences. The results were analyzed by p-value and Increas e·Decrease percentage of experiments result's numerical value. Results:1. Inquire into frequency in use of each stress stimulus and measuring items, the restriction stimulus stress and measuring the content of catecholamines are numerous.2. Significance of stress stimuluses based on experments's results is good by restriction stimulus.3. Oriental Medicine's meaning for stress is pathological phenomenon of Seven Emotion(七情). Stagnant the Energy(氣鬱), the Fire(火), Dam(痰), Lack of the general Blood thing(血虛), and reaction of an individual body.4. Inguire into the effects of frequency in use of experiments's Herb drugs, Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛痰) are numerous.5. From a Sasang Medical point of view, experimental use of Herb Drugs are Soeum-in(少陰人) Herb Drugs are numerous.According to above results, it is considered that Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛淡), and Soeum-in(少陰人) Herb Drugs are used to prevent stress and related diseases.

• Archives of Pharmacal Research
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• v.27 no.11
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• pp.1168-1176
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• 2004

Exposure to stress is known to precipitate or exacerbate many reproductive dysfunctions such as dysmenorrhea and infertility. Abnormalities of the reproductive system, as shown by reduced ovulation, fertilization and early embryonic development, are frequently seen in dysmenorrhea and infertility. It has been generally accepted that Gamisoyosan (GSS) is a useful prescription for treating insomnia, dysmenorrhea and infertility induced by a stress. Also GSS has been used traditionally to improve systemic circulation and biological energy production. Based on these, this study investigates whether GSS improved ovarian dysfunction caused by stress in mice. Mice were subjected to stress by electric shock on the foot for 30 min daily for a week and treated with GSS at 500 / body weight per day for one week. Thereafter, changes body weight, adrenal weight, ovulation rate, in vitro and in vivo fertilization, embryonic development and estradiol concentrations were measured. GSS markedly increased the body weight of mice with stress, but not normal mice. The administration of GSS caused a reduction in adrenal weight in stressed mice. GSS also had significant positive effects on ovulation rate, estradiol production, in vivo and in vitro fertilization rates and embryonic development. These results indicate that GSS can improve the reproductive dysfunctions caused by stress, and these may production biological energy.

• Journal of Korean Academy of Nursing
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• v.46 no.4
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• pp.583-597
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• 2016

Purpose: The study was done to evaluate the effects a Stress Management Program (SMP) on stress, problem solving skills, and quality of life for hospitalized patients with Schizophrenia. Methods: A mixed method design was used: a combination of a repeated-measure design with a non-equivalent control group and qualitative data collection. The participants were 40 patients with schizophrenia admitted in three psychiatric hospitals. The experimental group (n=20) received the SMP twice a week for a total of 8 weeks. Results: Study results revealed that the SMP was effective for stress (F=321.02, p<.001), problem solving ability (F=246.28, p<.001), and quality of life (F=63.35, p<.001) for hospitalized persons with schizophrenia. Conclusion: The results suggest that a SMP can be an effective strategy to reduce patients' hospitalization stress, and improve problem solving skills and quality of life. Therefore, it is recommended that mental health nurses use this stress management program in clinical practice to assist adaptation to hospitalization for persons with schizophrenia.

• Asia-Pacific Journal of Business
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• v.10 no.2
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• pp.99-116
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• 2019

In this study, we examined the effects of self-efficacy and self-esteem on employment anxiety based on existing prior study and verified the moderating effect of academic stress between self-efficacy and employment anxiety, and moderating effect of academic stress between self-esteem and employment anxiety and the analysis result are as follows. The first result shows that self-efficacy and self-esteem negatively affect employment anxiety. Second, academic stress has not played a role of moderating in the relationship between self-efficacy and employment anxiety. As academic stress increases, employment anxiety increases. However, the regression analysis results confirmed that the academic stress can be an independent variable that explains employment anxiety. Finally, academic stress plays a role of moderating in the relationship between self-esteem and employment anxiety. This means that students with relatively high self-esteem are less likely to have employment anxiety than those who do not, and that increasing academic stress increases the employment anxiety of college students.

• Korean Journal of Clinical Laboratory Science
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• v.50 no.1
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• pp.63-70
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• 2018

The purpose of this study was to analyze the factors affecting suicidal ideation, and suggest the implications for suicide prevention policy among college students based on that analysis. Empirical model including the affecting factors, such as college life stress, stress coping type, self-esteem, and maladjustment perfectionism, was developed based on the previous studies. The data were collected from 350 college students at Busan Metropolitan City areas using a self-administered structured questionnaire. The major results of this study are as follows. First, suicidal ideation was significantly lower among students with higher campus life satisfaction. Second, significant positive affecting factors on suicidal ideation were maladjustment perfectionism, interpersonal stress, boys, emotion-oriented coping type, whereas, negative factors were self-esteem. Among the significant affecting factors, self-esteem had the greatest influence. These results suggest that measures improving college life satisfaction and education and training programs for improving human relation skills and stress-coping types, mitigating maladjustment perfectionism, and enhancing self-esteem should be explored and executed properly.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.395-402
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• 2018

This study was conducted to identify factors influencing subjective happiness among nursing students. Participants consisted of 147 nursing students who were in the third and fourth years at two universities located in the Chungbuk and Kyungbuk provinces. Data were collected using questionnaires that looked at college-based stress, clinical-based stress, self-esteem, and subjective happiness from September 26 to October 29, 2016. Collected data were analyzed using the SPSS 22.0 statistics program with descriptive statistics, an independent t-test, analysis of variance (ANOVA), Scheffe's test, and hierarchical regression. The mean score for subjective happiness was 19.91 (range: 4 to 28). The mean for college-based stress was 2.92, and clinical-based stress was 2.61 (range: 1 to 5). The mean for self-esteem was 29.74 (range: 10 to 40). The significant predictors of subjective happiness in nursing students were self-esteem (p<.001), economic status (p=.002), interpersonal relationships (p=.001), and satisfaction with their major (p=.003). The explanatory power of variance was 68%, with self-esteem serving as the major predictor variable for subjective happiness. Therefore, we need various strategies that can enhance self-esteem, satisfaction with the major, and interpersonal relationships in order to improve nursing students' subjective happiness.

• Journal of Technologic Dentistry
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• v.43 no.2
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• pp.42-47
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• 2021

Purpose: The purpose of this study was to evaluate the stability of abutment screws used with the zirconia fixture-based implant system and compare them with those used with the existing titanium fixture system via the finite element method. Methods: A single implant-supported restoration was designed for the finite element analysis. A universal analysis program was used to set 8 occlusal points along the direction to the long axis of the implant, and an occlusal load of 700 N was applied. Results: In all models (Zir and Ti-fixture model), the screw threads presented with the highest von Mises stress (VMS) values, whereas the head and end presented with the lowest VMS values. The VMS of the screw used in the zirconia-fixture model was 5.97% lower than that used in the titanium-fixture model (261.258 vs. 276.911 MPa, respectively) despite statistical significance. Furthermore, the zirconia fixture (352.912 MPa) had a higher stress value (8.42%) than the titanium fixture (332.331 MPa). In a completely tightened titanium fixture implant system, the stress was concentrated in the implant-abutment connection interface, the zirconia fixture presented with a stable stress distribution. Conclusion: Although the zirconia fixture demonstrated a high VMS value, owing to the stiffness and elasticity coefficients of the material, the stress generated in the abutment screws was similar in all models. In conclusion, the zirconia fixture-based implant system presented with a more stable stress distribution in the abutment screws than the titanium fixture-based implant system.

• Korean Journal of Adult Nursing
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• v.16 no.1
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• pp.90-101
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• 2004

Purpose: The purpose was to examine the effectiveness of a psychosocial stress management program on stress and coping in student nurses. Method: A nonequivalent control group pre-posttest design was used. A convenience sample of 24 students from the Department of Nursing, Wonju College of Medicine, Yonsei University were assigned to experimental (n=12) and control groups(n=12). Stress was measured using the Visual Analog Scale (10 points) and blood cortisol. Coping was measured using a scale modified by So (1995) based on the Ways of Coping Checklist developed by Folkman and Lazarus (1985). Depression was measured using the CES-D by Radloff (1977) and state anxiety, using the State Anxiety Inventory by Spielberger (1976). The psychosocial stress management program included education, relaxation (Korean Dan Jeon-typed Breathing and music), and social support. Result: Results showed for the two groups, 1) a significant difference in stress scores (U= 19.50, p=0.002), 2) no difference in cortisol levels (8am, 4pm), 3) a significant difference in problem-focused coping (U=25.50, =0.007), 4) no difference in emotion-focused coping, and 5) no difference in state anxiety and depression. Conclusion: By utilizing the program, students were able to learn how to control their stress and improve their coping. Therefore with a partial modification, psychosocial stress management can be useful for continual management of stress in student nurses.

• Natural Product Sciences
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• v.22 no.3
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• pp.201-208
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• 2016

Here in this study, we investigated the lifespan-extending effect and underlying mechanism of methanolic extract of Moringa olelifa leaves (MML) using Caenorhabditis elegans (C. elegans) model system. To define the longevity properties of MML we conducted lifespan assay and MML showed significant increase in lifespan under normal culture condition. In addition, MML elevated stress tolerance of C. elegans to endure against thermal, oxidative and osmotic stress conditions. Our data also revealed that increased activities of antioxidant enzymes and expressions of stress resistance proteins were attributed to MML-mediated enhanced stress resistance. We further investigated the involvement of MML on the aging-related factors such as growth, food intake, fertility, and motility. Interestingly, MML significantly reduced growth and egg-laying, suggesting these factors were closely linked with MML-mediated longevity. We also observed the movement of aged worms to estimate the effects of MML on the health span. Herein, MML efficiently elevated motility of aged worms, indicating MML may affect health span as well as lifespan. Our genetic analysis using knockout mutants showed that lifespan-extension activity of MML was interconnected with several genes such as skn-1, sir-2.1, daf-2, age-1 and daf-16. Based on these results, we could conclude that MML prolongs the lifespan of worms via activation of SKN-1 and SIR-2.1 and inhibition of insulin/IGF pathway, followed by DAF-16 activation.