• 한국동물생명공학회지
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• 제37권1호
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• pp.13-16
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• 2022

The use of animals heavily impacts the mental health of researchers performing the animal experiments. The animal researchers need to take care of animals but also give pain and sacrifice them at the same time. This circumstance can cause a variety of mental stress to the researchers. The stress generated in the laboratory would not only negatively affect the management of animals and the research results, but also would harm the researchers' physical and mental health. Because the feeling of sympathy for animals is a natural feature of humanity, psychological stress following a laboratory animal's death after use is not surprising. It is necessary to revise the relevant laws based on understanding the difficulties of animal researchers in society and to develop related educational programs at the national level to help the psychology and emotions of researchers who conduct animal experiments.

• 동의신경정신과학회지
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• 제8권1호
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• pp.111-125
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• 1997

This study was done in order to investigate Oriental Medicine's meaning on stress, the stress is due to animal experiments.Methods:This research was done by animal experiments's results based on 41 animal experiment treatises carried out by 24 prescriptions about stress control. Each experiments were compared with same conditions, minimizing the experiments differences. The results were analyzed by p-value and Increas e·Decrease percentage of experiments result's numerical value. Results:1. Inquire into frequency in use of each stress stimulus and measuring items, the restriction stimulus stress and measuring the content of catecholamines are numerous.2. Significance of stress stimuluses based on experments's results is good by restriction stimulus.3. Oriental Medicine's meaning for stress is pathological phenomenon of Seven Emotion(七情). Stagnant the Energy(氣鬱), the Fire(火), Dam(痰), Lack of the general Blood thing(血虛), and reaction of an individual body.4. Inguire into the effects of frequency in use of experiments's Herb drugs, Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛痰) are numerous.5. From a Sasang Medical point of view, experimental use of Herb Drugs are Soeum-in(少陰人) Herb Drugs are numerous.According to above results, it is considered that Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛淡), and Soeum-in(少陰人) Herb Drugs are used to prevent stress and related diseases.

• Archives of Pharmacal Research
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• 제27권11호
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• pp.1168-1176
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• 2004

Exposure to stress is known to precipitate or exacerbate many reproductive dysfunctions such as dysmenorrhea and infertility. Abnormalities of the reproductive system, as shown by reduced ovulation, fertilization and early embryonic development, are frequently seen in dysmenorrhea and infertility. It has been generally accepted that Gamisoyosan (GSS) is a useful prescription for treating insomnia, dysmenorrhea and infertility induced by a stress. Also GSS has been used traditionally to improve systemic circulation and biological energy production. Based on these, this study investigates whether GSS improved ovarian dysfunction caused by stress in mice. Mice were subjected to stress by electric shock on the foot for 30 min daily for a week and treated with GSS at 500 / body weight per day for one week. Thereafter, changes body weight, adrenal weight, ovulation rate, in vitro and in vivo fertilization, embryonic development and estradiol concentrations were measured. GSS markedly increased the body weight of mice with stress, but not normal mice. The administration of GSS caused a reduction in adrenal weight in stressed mice. GSS also had significant positive effects on ovulation rate, estradiol production, in vivo and in vitro fertilization rates and embryonic development. These results indicate that GSS can improve the reproductive dysfunctions caused by stress, and these may production biological energy.

• 대한간호학회지
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• 제46권4호
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• pp.583-597
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• 2016

Purpose: The study was done to evaluate the effects a Stress Management Program (SMP) on stress, problem solving skills, and quality of life for hospitalized patients with Schizophrenia. Methods: A mixed method design was used: a combination of a repeated-measure design with a non-equivalent control group and qualitative data collection. The participants were 40 patients with schizophrenia admitted in three psychiatric hospitals. The experimental group (n=20) received the SMP twice a week for a total of 8 weeks. Results: Study results revealed that the SMP was effective for stress (F=321.02, p<.001), problem solving ability (F=246.28, p<.001), and quality of life (F=63.35, p<.001) for hospitalized persons with schizophrenia. Conclusion: The results suggest that a SMP can be an effective strategy to reduce patients' hospitalization stress, and improve problem solving skills and quality of life. Therefore, it is recommended that mental health nurses use this stress management program in clinical practice to assist adaptation to hospitalization for persons with schizophrenia.

• 아태비즈니스연구
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• 제10권2호
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• pp.99-116
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• 2019

In this study, we examined the effects of self-efficacy and self-esteem on employment anxiety based on existing prior study and verified the moderating effect of academic stress between self-efficacy and employment anxiety, and moderating effect of academic stress between self-esteem and employment anxiety and the analysis result are as follows. The first result shows that self-efficacy and self-esteem negatively affect employment anxiety. Second, academic stress has not played a role of moderating in the relationship between self-efficacy and employment anxiety. As academic stress increases, employment anxiety increases. However, the regression analysis results confirmed that the academic stress can be an independent variable that explains employment anxiety. Finally, academic stress plays a role of moderating in the relationship between self-esteem and employment anxiety. This means that students with relatively high self-esteem are less likely to have employment anxiety than those who do not, and that increasing academic stress increases the employment anxiety of college students.

• 대한임상검사과학회지
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• 제50권1호
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• pp.63-70
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• 2018

본 연구의 목적은 남녀 대학생을 대상으로 사회인구학적 특성과 대학생활 스트레스, 스트레스 대처방식, 자아존중감, 부적응적 완벽주의가 자살생각에 미치는 영향을 규명함으로써 대학생의 자살예방정책 마련을 위한 시사점을 제공하는데 있다. 부산경남지역 대학생 350명을 대상으로 자기기입식 설문조사방법으로 자료를 수집하여 실증 분석하였다. 본 연구의 주요 결과를 요약하면 다음과 같다. 첫째, 자살생각은 사회인구학적 특성 중 대학생활 만족도에서 통계적으로 유의한 차이를 보였다. 즉, 대학생활만족도가 낮은 그룹에서 자살생각이 강했다. 둘째, 제변수들의 상관관계를 분석한 결과, 자살생각은 자아존중감, 대학생활 만족도, 적극적 스트레스 대처방법인 문제중심 스트레스 대처방식 순으로 뚜렷한 역의 상관관계를 보이고 있고 반면에, 부적응적 완벽주의, 대학생활 스트레스, 소극적 스트레스 대처인 정서중심 스트레스 대처방식 순으로는 뚜렷한 정의 상관관계를 보였다. 즉 자아존중감이 높을수록, 대학생활 만족도가 높을수록, 문제중심 스트레스 대처방식을 사용할수록 자살생각이 낮아지고, 부적응적 완벽주의가 높을수록, 대학생활 스트레스가 높을수록, 정서중심 스트레스 대처방식을 사용할수록 자살생각이 높아지는 것으로 분석된다. 셋째, 연구 대상자의 자살생각에 영향을 미치는 요인을 규명하기 위한 회귀 분석의 결과, 부적응적 완벽주의, 대인관계 스트레스, 남학생, 정서중심 스트레스 대처방식 순으로 유의한 정의 영향을 미치는 것으로 나타났고, 자아존중감은 유의한 역의 영향을 미치는 것으로 나타났다. 특히 자아존중감의 영향이 가장 컸다. 즉, 부적응적 완벽주의가 높을수록, 대인관계 스트레스가 높을수록, 여학생보다 남학생에서, 정서중심 스트레스 대처방식을 사용할수록 자살생각이 높아지고, 자아존중감이 높을수록 자살생각은 낮아지는 것으로 분석된다. 이상의 결과를 종합하면, 대학생활만족도를 높이기 위한 노력이 대학생의 자살생각을 완화시키는 효과가 있으며, 대학생의 자살예방을 위해서는 대인관계 기술 향상과 스트레스 대처방식의 개선, 부적응적 완벽주의 성향의 완화, 그리고 자아존중감 강화를 위한 교육 및 훈련이 필요함을 시사한다. 특히 대학생의 자아존중감 향상을 위한 다각적인 방안의 모색이 중요하다고 판단된다.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.395-402
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• 2018

본 연구는 간호학생의 스트레스, 자아존중감, 주관적 행복감 정도를 알아보고 주관적 행복감에 영향을 미치는 요인을 파악하기 위하여 시도되었다. 연구대상은 충북지역과 경북지역에 소재하는 2개의 간호대학에서 임상실습을 경험한 3,4학년 간호학생 중 설문 조사에 동의한 147명이었다. 자료 수집은 구조화된 설문지를 이용하여 대상자의 스트레스, 자아존중감 및 주관적 행복감을 조사하였다. 자료수집기간은 2016년 9월 26일부터 동년 10월 29일까지였다. 자료 분석은 SPSS 22.0을 이용하여 기술통계, independent t test, ANOVA, scheffe's test와 위계적 회귀분석을 실시하였다. 연구 결과 대상자의 주관적 행복감의 평균은 19.91점(28점 만점), 대학 차원 스트레스 평균 2.91점(5점 만점), 임상 차원 스트레스 평균 2.61점(5점 만점), 자아존중감 평균 29.74점(40점 만점)이었다. 위계적 회귀분석 결과 대상자의 주관적 행복감에 영향을 미치는 요인은 자아존중감(p<.001), 경제상태(p=.002), 대인관계(p=.001), 전공만족도(p=.003) 순이었으며, 주관적 행복감에 대한 이들 변인들의 설명력은 68%로, 주관적 행복감에 가장 큰 영향을 미친 변수는 자아존중감으로 나타났다. 이에 간호학생의 주관적 행복감을 증진시키기 위하여 자아존중감과 전공만족도를 높이고 대인관계를 증진시키는 다양한 전략들이 요구된다.

• 대한치과기공학회지
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• 제43권2호
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• pp.42-47
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• 2021

Purpose: The purpose of this study was to evaluate the stability of abutment screws used with the zirconia fixture-based implant system and compare them with those used with the existing titanium fixture system via the finite element method. Methods: A single implant-supported restoration was designed for the finite element analysis. A universal analysis program was used to set 8 occlusal points along the direction to the long axis of the implant, and an occlusal load of 700 N was applied. Results: In all models (Zir and Ti-fixture model), the screw threads presented with the highest von Mises stress (VMS) values, whereas the head and end presented with the lowest VMS values. The VMS of the screw used in the zirconia-fixture model was 5.97% lower than that used in the titanium-fixture model (261.258 vs. 276.911 MPa, respectively) despite statistical significance. Furthermore, the zirconia fixture (352.912 MPa) had a higher stress value (8.42%) than the titanium fixture (332.331 MPa). In a completely tightened titanium fixture implant system, the stress was concentrated in the implant-abutment connection interface, the zirconia fixture presented with a stable stress distribution. Conclusion: Although the zirconia fixture demonstrated a high VMS value, owing to the stiffness and elasticity coefficients of the material, the stress generated in the abutment screws was similar in all models. In conclusion, the zirconia fixture-based implant system presented with a more stable stress distribution in the abutment screws than the titanium fixture-based implant system.

• 성인간호학회지
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• 제16권1호
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• pp.90-101
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• 2004

Purpose: The purpose was to examine the effectiveness of a psychosocial stress management program on stress and coping in student nurses. Method: A nonequivalent control group pre-posttest design was used. A convenience sample of 24 students from the Department of Nursing, Wonju College of Medicine, Yonsei University were assigned to experimental (n=12) and control groups(n=12). Stress was measured using the Visual Analog Scale (10 points) and blood cortisol. Coping was measured using a scale modified by So (1995) based on the Ways of Coping Checklist developed by Folkman and Lazarus (1985). Depression was measured using the CES-D by Radloff (1977) and state anxiety, using the State Anxiety Inventory by Spielberger (1976). The psychosocial stress management program included education, relaxation (Korean Dan Jeon-typed Breathing and music), and social support. Result: Results showed for the two groups, 1) a significant difference in stress scores (U= 19.50, p=0.002), 2) no difference in cortisol levels (8am, 4pm), 3) a significant difference in problem-focused coping (U=25.50, =0.007), 4) no difference in emotion-focused coping, and 5) no difference in state anxiety and depression. Conclusion: By utilizing the program, students were able to learn how to control their stress and improve their coping. Therefore with a partial modification, psychosocial stress management can be useful for continual management of stress in student nurses.

• Natural Product Sciences
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• 제22권3호
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• pp.201-208
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• 2016

Here in this study, we investigated the lifespan-extending effect and underlying mechanism of methanolic extract of Moringa olelifa leaves (MML) using Caenorhabditis elegans (C. elegans) model system. To define the longevity properties of MML we conducted lifespan assay and MML showed significant increase in lifespan under normal culture condition. In addition, MML elevated stress tolerance of C. elegans to endure against thermal, oxidative and osmotic stress conditions. Our data also revealed that increased activities of antioxidant enzymes and expressions of stress resistance proteins were attributed to MML-mediated enhanced stress resistance. We further investigated the involvement of MML on the aging-related factors such as growth, food intake, fertility, and motility. Interestingly, MML significantly reduced growth and egg-laying, suggesting these factors were closely linked with MML-mediated longevity. We also observed the movement of aged worms to estimate the effects of MML on the health span. Herein, MML efficiently elevated motility of aged worms, indicating MML may affect health span as well as lifespan. Our genetic analysis using knockout mutants showed that lifespan-extension activity of MML was interconnected with several genes such as skn-1, sir-2.1, daf-2, age-1 and daf-16. Based on these results, we could conclude that MML prolongs the lifespan of worms via activation of SKN-1 and SIR-2.1 and inhibition of insulin/IGF pathway, followed by DAF-16 activation.