• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5155-5160
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• 2014

Aim: To investigate the efficacy and safety of lobaplatin-transcatheter arterial chemoembolization (TACE) combined with radioactive $^{125}I$ seed implantation in treatment of primary hepatocellular carcinoma (HCC). Methods: 75 patients with primary HCC were enrolled in the study, among them 43 receiving lobaplatin-TACE (TACE group) and 32 lobaplatin-TACE combined with $^{125}I$ seed implantation (TACE+$^{125}I$ group). After treatment, the local remission rates and postoperative complications of two groups were compared using the Pearson Chi-square test. Overall survival in the two groups was calculated using Kaplan-Meier survival curves and the differences were tested using Log-rank test. Results: There were 7 cases of complete response (CR), 13 of partial response (PR), 6 of stable disease (SD) and 17 of progressive disease (PD) in the TACE group, with 13 cases of CR, 9 of PR, 5 of SD and 5 of PD in the TACE+$^{125}I$ group. The disease control rates of TACE and TACE+$^{125}I$ group were 60.5% (26/43) and 84.4% (27/32), respectively, with a significant difference between them (P < 0.05). The survival rates at 6, 12 and 18 months in the TACE group were 100.0%, 81.8% and 50.0%, respectively, and those in TACE+$^{125}I$ group were 100.0%, 93.8% and 65.6%. The mean survival times in the TACE and TACE+$^{125}I$ groups were 19.5 and 22.9 months, respectively. There was a significant difference in the overall survival rate between two groups (P < 0.05). No serious complications were encountered in either group. Conclusion: Lobaplatin-TACE combined with $^{125}I$ seed implantation is favorable and safe for treatment of primary HCC.

• 대한예방한의학회지
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• 제12권1호
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• pp.49-60
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• 2008

This study investigated the Oriental medicine knowledge and educational requirement of medical staff working in Oriental-Western collaborative medicine hospitals(except for Oriental and Western medicine doctors) based on the recognition that not only mutual understanding and cooperation between Oriental and Western medicine doctors but also the knowledge of Oriental medicine of medical support staff such as nurses, medical technologists, pharmacists and administrative staff are very important to promote Oriental-Western collaborative medical treatment. The study results are summarized as follows : First, it was found that the ratio of nurses who took Oriental medicine education was much higher than those of other groups. They took Oriental medicine education in the types of school curriculum (27.0%) and special lectures in workplace(20.4%). Second, many of the people who took Oriental medicine education were found to be not satisfied with the education in general - 32.7% of them answered the education content was "so so" and 48.4% of them answered "unsatisfactory." Third, the general necessity of Oriental medicine education was found to be an average of 3.60 out of 5, and the number was higher "after employment"(average=3.85) than "before employment"(average=3.04). Fourth, the study found that Oriental-Western collaborative medicine hospital staff are well aware of the necessity of the knowledge of Oriental medicine in the cases of communications between different occupational types, consultations with patients or their guardians, treatment and nursing and the establishment of the practice of specialized Oriental medicine institutes. Fifth, the levels of Oriental medicine knowledge showed a difference in average value according to the role range(p<0.000), and it was found that there is an interaction effect between occupation type and role range(p<0.015).

• Journal of Acupuncture Research
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• 제23권2호
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• pp.197-205
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• 2006

Objectives : To examine the effects of the collaborative Oriental and Western medicine, we treated a gouty arthritis patient with acute inflammation and liver injury with a combination of Oriental and Western treatments. Methods : Acupuncture, Bangphungtongsung-San(Fangfengtongsheng-san)', 'Kangwhaljetong-Um(Qianghuochutong-yin)', and 'Sosiho-Tang(Xiaochaihu-tang) were offered to an acute gouty arthritis patient with NSAIDs, Corticosteroids and allopurinol. Laboratory data were observed for the duration of hospital days. Results : In spite of Oriental treatments, NSAIDs administration caused liver injury, but continuous Oriental treatments with small amount of Corticosteroids and allopurinol brought recovery of liver function and gouty arthritis. Confusion : Collaborative treatments of Oriental and Western medicine are better than independent Western treatment for gouty arthritis with acute inflammation and liver injury. Further studies will be required to ascertain the collaborative treatment with Oriental and Western medicine for gouty arthritis and other diseases.

• Journal of Acupuncture Research
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• 제37권3호
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• pp.161-166
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• 2020

Background: The purpose of this study was to investigate the characteristics and direction of treatment for peripheral facial palsy (PFP) based on medical collaboration between Western and Korean medicine departments. Methods: There were 195 outpatients with PFP identified retrospectively by examining electronic medical records. These patients were treated with Korean and Western medicine from January 1^st, 2018 to December 31^st, 2018 at the Kyung Hee University hospital. Records were analyzed according to the patients' demographic characteristics and clinical features of the collaborative combined treatment. Results: According to the collaborative treatment pathway, the number of patients consulted from Western medicine departments was more than consulted from Korean department for the first time. The time taken by the Western medicine departments to consult with the patients at the Korean center for the first time was 14.9 days from the onset of symptoms. Acupuncture was the most frequently used Korean medicine treatment. The total treatment period for Korean medicine sessions and intervals were 91.9 days, 23 times and 3.6 days, respectively. When the Korean medicine center consulted with Western medicine departments, the time taken until the first consultation was 8.5 days from the onset of symptoms. Medication was the most used treatment, prescribed after 3.1 days. The most frequently used clinical test was an electromyogram, and this was performed after 20.5 days. The total treatment period, sessions and intervals were 21.2 days, 2.8 times and 5 days, respectively. Conclusion: The clinical status of collaborative treatment for PFP was determined including the timing and interval of consultation according to treatments.

• 의료법학
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• 제24권3호
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• pp.27-55
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• 2023

우리나라에서 통상 사용하는 협진의 의미는 동일한 의료기관 내에서 서로 다른 진료과목의 의사가 환자를 함께 치료하는 경우로 이해된다. 그렇기 때문에 협진은 다양한 의료관여자들이 각자의 전문성에 의거하여 역할을 분담하여 환자를 치료하는 의료팀의 양상을 띠게 된다. 또한 의료팀 내 다른 진료과목의 의사는 동등한 지위에서 각각 전문성에 의거하여 수평적 분업을 하게 되므로 협진은 분업의 원칙에 따라 법적 책임이 분배된다. 대법원도 "여러 명의 의사가 분업이나 협업을 통하여 의료행위를 담당하는 경우 먼저 환자를 담당했던 의사는 이후 환자를 담당할 의사에게 환자의 상태를 정확하게 알려 적절한 조치를 할 수 있도록 해야 한다."고 하여 의료팀을 이루어 환자를 함께 치료하는 경우를 인정하고, 의사의 협진의무에 대하여 판단하고 있다. 다수의 진료과목이 있는 의료기관 내에서 서로 다른 진료과목의 의사가 분업이나 협업을 통하여 의료행위를 담당하게 되는 협진의 경우, 환자를 담당했던 의사는 환자의 상태에 따라 협진 여부를 결정하여야 하며, 이후 환자를 담당할 진료과목의 의사에게 환자의 상태를 정확하게 알려 적절한 조치를 취하게 하여야 한다. 협진을 하게 된 후임 의사 또한 환자에 대한 치료 종료 시까지 협진을 요청했던 전임 의사에 대하여 환자의 상태와 관련된 치료사항을 적극적으로 고지하고 서로 소견을 교환하여야 할 것이다. 다만 협진의 필요성에 대한 결정은 당시 환자의 상태에 따라 판단이 이루어져야 하는 것으로, 모든 경우에 협진의무가 강제되는 것이라고 단언할 수는 없다. 그리고 협진의 필요성에 대한 결정에 있어서 과실이 존재하는지 여부는 의사의 주의의무 판단에 대한 법리가 적용될 것이다.

• 한국초등과학교육학회지:초등과학교육
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• 제36권3호
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• pp.181-192
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• 2017

In this study, the effects of the small group collaborative learning on students' achievement, the retention of the achievement, communication anxiety, and science learning motivation were investigated. The aptitude-treatment interaction between the level of students' self-directed learning ability and the intervention was also examined. Two classes (38 students) from an elementary school were respectively assigned to a control group and a treatment group. A self-directed learning ability test, a communication anxiety test, and a science learning motivation test were administered as pretests. The intervention lasted for 8 class periods. After instruction, an achievement test, the communication anxiety test, and the science learning motivation test were administered. An achievement retention test were also administered after four weeks. The results indicated that there were significant treatmentaptitude interaction effects in the achievement test scores and the achievement retention test scores. In the communication anxiety and the science learning motivation, however, any significant difference was not found between the scores of the treatment group and the control group. Educational implications are discussed.

• 동의생리병리학회지
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• 제32권2호
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• pp.134-140
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• 2018

This study aims to evaluate healthcare providers' satisfaction and demands pertaining to the collaborative first-stage pilot project between Korean medicine and Western medicine. This survey was conducted via electronic mail among 33 healthcare providers participating in the pilot project. Likert type 5-point scale or Likert type 7-point scale was used to evaluate each item. The response of '${\geq}4$' on the 5-point scale, and '${\geq}5$' on the 7-point scale were analyzed as positive answers. A total of 27 healthcare providers (81.8%) responded, of which 9 were western medical doctors (33.3%) and 18 were Korean medical doctors (66.7%). In respect to satisfaction of the pilot project, 88.9% gave positive responses on improved patients' convenience, 59.3% on treatment efficiency and 55.6% on diagnosis efficiency. In terms of self-evaluation on the pilot project, 70.4% gave positive answers on changes in quality of collaborative treatment, 74.1% on cooperation of results, 63.0% on cooperation of structure and 51.9% on cooperation of process. In terms of demand for collaborative treatment or the pilot project, 'standardized manual' and 'simplification of administrative procedures' showed highest demand, resulting up to 88.9%, followed by 85.2% demanding more public relations and 63.9% demanding enlargement of participating hospitals. This survey revealed that healthcare providers are generally satisfied with patients' convenience and treatment effects. Further studies are needed to develop a standardized manual, simplified administrative procedures, and expanded pilot project contents.

• 정보관리학회지
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• 제37권2호
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• pp.71-93
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• 2020

오늘날 다양한 질병의 출현과 빠르게 변화하는 의료환경에 보다 효과적으로 대처하기 위해 대학병원 내에서 여러 진료과들이 협업진료를 수행하고 있다. 이러한 협업진료는 매우 중요하며 의료 현장에서 이미 보편화되어 있다. 그럼에도 불구하고, 이에 대한 연구, 특히 진료과들이 어떻게 협업을 하고 있는지에 대한 연구는 전무하다. 따라서 본 연구는 대학병원 내의 진료과 간의 협업진료 관계를 탐색하여 진료협업 네트워크 특성들이 연도별 및 계절별로 어떻게 달라지는지를 고찰하는 것에 목적이 있다. 본 연구는 국내 A대학교 대학병원에서 이루어진 29개 진료과 사이의 협업 진료를 연도별 및 계절별로 나누어 29개 진료과 협업 네트워크를 분석하였다. 협업진료의 요청 및 피요청에 따라 방향네트워크를 구성하였으며, 매개중심성, 아이겐벡터중심성, 근접중심성 분석, 에고 네트워크 분석 및 팩션분석과 더불어 추후 인터뷰도 실시하였다. 본 연구는 최초의 진료과 간의 협업 네트워크 분석을 수행하였으며, 의료기관 내에서의 동선을 고려한 진료과의 위치 및 공간 구성에 새로운 통찰력을 제시할 것으로 기대된다.

• Journal of Ginseng Research
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• 제48권3호
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• pp.310-322
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• 2024

Background: Osteosarcopenia is a common condition characterized by the loss of both bone and muscle mass, which can lead to an increased risk of fractures and disability in older adults. The study aimed to elucidate the response of various mouse strains to treatment with Rg3, one of the leading ginsenosides, on musculoskeletal traits and immune function, and their correlation. Methods: Six Collaborative Cross (CC) founder strains induced muscle atrophy and bone loss with dexamethasone (15 mg/kg) treatment for 1 month, and half of the mice for each strain were orally administered Rg3 (20 mg/kg). Different responses were observed depending on genetic background and Rg3 treatment. Results: Rg3 significantly increased grip strength, running performance, and expression of muscle and bone health-related genes in a two-way analysis of variance considering the genetic backgrounds and Rg3 treatment. Significant improvements in grip strength, running performance, bone area, and muscle mass, and the increased gene expression were observed in specific strains of PWK/PhJ. For traits related to muscle, bone, and immune functions, significant correlations between traits were confirmed following Rg3 administration compared with control mice. The phenotyping analysis was compiled into a public web resource called Rg3-OsteoSarco. Conclusion: This highlights the complex interplay between genetic determinants, pathogenesis of muscle atrophy and bone loss, and phytochemical bioactivity and the need to move away from single inbred mouse models to improve their translatability to genetically diverse humans. Rg3-OsteoSarco highlights the use of CC founder strains as a valuable tool in the field of personalized nutrition.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4641-4646
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• 2013

Objective: To explore clinical experience and propose new ideas for treating children diagnosed with orbital rhabdomyosarcoma (RMS). Methods: We retrospectively analyzed the clinical data for30 patients (16 males and 14 females, with a median age of 6.2 years) with primary orbital RMS who were enrolled in the Department of Eye Oncology and Pediatrics of our hospital from November 2004 to December 2012. International Rhabdomyosarcoma Organization Staging Standards indicated that among the 30 patients, 4 cases were in phase II, 20 were in phase III, and 6 were in phase IV. All patients underwent a multidisciplinary collaborative model of comprehensive treatment (surgery, chemotherapy, external radiotherapy, $^{125}I$ radioactive particle implantation, and autologous peripheral blood stem-cell transplantation). Results: Follow-up was conducted until March 2013, with a median follow-up time of 47.2 months (5 to 95 months), and 7 deaths occurred. The 2-year estimated survival rate reached 86.1%, the ${\geq}3$-year estimated survival rate was 77%, and the 5-year estimated survival rate was 70.6%. Conclusions: The multidisciplinary collaborative model can be a safe and effective approach to the comprehensive treatment of children with orbital RMS. It has clinical significance in improving the tumor remission rate.