• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.15-21
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• 2010

Previously standardization study for identifying 5 types of pattern identification of stroke patients has been performed and the Korean standard of pattern identification (II) was developed. In the present study we investigated the interactions between total indices designated by the Korean standard of pattern identification(KSPI II) and indices for PI of Cold-Heat and Deficiency-Excess. Indicators for Cold-Heat and Deficiency-Excess are isolated from 58 indices through the survey of oriental medicine doctors and their relationship with KSPI-II indices was analyzed by corresponding analysis method using data of 1581 stroke patients. Means and standard deviations indicated that 2 Cold indices, 14 Heat indices, 12 Deficiency indices, and 5 Excess indices were included for Cold-Heat and Deficiency-Excess pattern identification. The results of corresponding analysis shows the relationship of 57 indices and 4 types of pattern identification (excluding 1 index and 1 pattern among 58 indices and 5 patterns) using the cross-tabulation which was obtained from the clinical data. Most of Cold and Heat index were divided to dimension 1(inertia 51.9%) obtained from the result of corresponding analysis. Deficiency and Excess index were partially associated with dimension 2(inertia 31.7%). These data suggest that pattern identification of Cold-Heat plays an role in the standardization of pattern identification in stroke, although further studies are required by various trials such as analysis of surveys and clinical data.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.4
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• pp.27-37
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• 2012

Purpose: Dysmenorrhea is mostly depending on the causative factor, which usually falls under the categories of Cold and Heat pattern in traditional Oriental medical theories and diagnosis. Thus, we investigated menstruation symptom and sign related to dysmenorrhea and verified the validity of Cold and Heat pattern identification. Methods: We investigated menstruation symptom and sign related to dysmenorrhea in total 14 gynecology-medical books including ${\ll}$Exemplar Of Korean Medicine (Dongui Bogam)${\gg}$ and whole body symptom and sign identifying Cold and Heat pattern at the same time. A survey based on this investigation was carried out targeting women of childbearing age. Results: According to 14 gynecology-medical books, polymenorrhea is relevant to Heat pattern, oligomenorrhea to Cold pattern and darkness of menstrual blood is relevant to Heat pattern. Among the total of 343 womens, 196 subjects suffered from dysmenorrhea. The number of dysmenorrhea with polymenorrhea(Heat pattern) was 6 person, with oligomenorrhea(Cold pattern) was 27 person. And the number of dysmenorrhea with darkness of menstrual blood(Heat pattern) was 39 person. As the result of checking correlations of menstrual symptom scores and whole body symptom scores, there was no significance of Cold and Heat pattern between menstrual symptoms and whole body symptoms. Conclusions: The results suggest that the period of menstrual cycle and the color of menstrual blood provides some informations of Cold and Heat pattern identification. But considering with other whole body symptom and sign is needed for more precise result.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.5
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• pp.341-346
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• 2018

The aims of this study were to evaluate the reliability and validity of the cold and heat pattern identification questionnaire (CHPIQ). From July 2015 to December 2015, 120 participants, university faculties, filled out CHPIQ by the way of self-reporting. Then two Korean medical doctors independently diagnosed them whether they belonged to cold pattern (CP) or not, and heat pattern (HP) or not. We evaluated the internal consistency using Cronbach's alpha coefficient, and the validity using the sensitivity and specificity through receiver operating characteristic-curve. The internal consistency (Cronbach's alpha coefficient) showed 0.754 (CP) and 0.753 (HP). The area under the curve was recorded with 0.884 (CP) and 0.786 (HP). The agreements between CHPIQ and experts were 82.8% (CP) and 72.9% (HP). The sensitivities showed 0.707 (CP) and 0.719 (HP), and the specificities were 0.935 (CP) and 0.736 (HP). This study suggests that CHPIQ is a reliable and valid instrument for estimating cold-heat pattern identification.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.29-40
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• 2019

Objectives : Hwanglyeonhaedok-tang(黃連解毒湯) is a representative herbal formula with "clear heat(淸熱)" effects. The aim of this study was to evaluate the effects of Hwanglyeonhaedok-tang-based intranasal herbal ointment Biyeom-go based on the cold and heat pattern identification questionnaire(CHPIQ). Methods : We performed a subgroup analysis of the previously published prospective observational study. A total of 58 patients with rhinitis were administered Biyeom-go for 4 weeks, and its effects on the Total Nasal Symptom Score(TNSS), Mini Rhinoconjunctivitis Quality of Life Questionnaire(Mini-RQLQ) score, and nasal endoscopy index score were analyzed based on CHPIQ. Results : Among the 58 patients, the heat and non-heat patterns were shown by 39 and 19 patients, respectively, while the cold and non-cold patterns were shown by 46 and 12 patients, respectively. The change in TNSS from baseline negatively correlated with the heat pattern score(p=0.011). Improvement in TNSS was greater in the heat pattern group than in the non-heat pattern group, with a borderline significant difference(p=0.07). Mini-RQLQ and nasal endoscopy index scores tended to be lower in the heat pattern group than in the non-heat pattern group, but without a statistically significant difference. Conclusion : The findings indicate that CHPIQ is a useful tool for the diagnostic and prognostic evaluation of patients with rhinitis. This study provides fundamental evidence of the close association between the cold-heat pattern in patients with rhinitis and the treatment effects of Biyeom-go.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.2
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• pp.17-26
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• 2016

Objectives : We presented the results of reliability study in advance, and analyzed agreement between Korean medicine doctors(KMDs)' diagnosis and cold-heat pattern identification questionnaire(CHPI)'s diagnosis. Methods : This survey was conducted from May 16 to 17, 2015. The subjects were 93 adults living in rural society. Diagnosis of CHPI was performed by 2 KMDs who have clinical experience more than 5 years. The KMDs' diagnosis was set as a reference index, and then we compare 23 items(cold pattern 11 items and heat pattern 12 items) of CHPI questionnaire and 15 items(cold pattern 8 items and heat pattern 7 items) that were brief form of it. We had cut-off value by standard of KMDs' diagnosis using receiver operating characteristic-curve(ROC-curve), with which we calculated agreement including kappa value. Correlation analysis between CHPI evaluation score by KMDs and by the questionnaire was fulfilled as well. Results : Agreement about 11 and 8 cold pattern items showed 87.1% together, and the value of kappa each recorded 0.742 and 0.741. Agreement about 12 and 7 heat pattern items suggested 81.7% and 78.5%, and the value of kappa showed 0.634 and 0.570. Correlation coefficients were 0.803 of 11 items and 0.761 of 8 items about cold pattern. In addition, correlation coefficients were 0.789 of 12 items and 0.767 of 7 items about heat pattern. The significant probability (p-value) was under 0.001. Conclusions : We have developed CHPI questionnaire involving reliability and agreement based on usual symptoms, and hope additional complements so that Korean medicine diagnostics and Korean preventive medicine would be improved.

• The Journal of Korean Medicine
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• v.42 no.4
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• pp.185-196
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• 2021

Objectives: Many symptoms of cold and heat patterns are related to the thermoregulation of the body. Thus, we aimed to study the association of cold and heat patterns with anthropometry/body composition. Methods: The cold and heat patterns of 2000 individuals aged 30-55 years were evaluated using a self-administered questionnaire. Results: Among the anthropometric and body composition variables, body mass index (-0.37, 0.39) and fat mass index (-0.35, 0.38) had the highest correlation coefficients with the cold and heat pattern scores after adjustment for age and sex in the cold-heat group, while the correlation coefficients were relatively lower in the non-cold-heat group. In the cold-heat group, the most parsimonious model for the cold pattern with the variables selected by the best subset method and Lasso included sex, body mass index, waist-hip ratio, and extracellular water/total body water (adjusted R² = 0.324), and the model for heat pattern additionally included age (adjusted R² = 0.292). Conclusions: The variables related to obesity and water balance were the most useful for predicting cold and heat patterns. Further studies are required to improve the performance of prediction models.

• The Journal of Internal Korean Medicine
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• v.43 no.6
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• pp.1063-1074
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• 2022

Objectives: The aim of this study was to investigate the differences in the prevalence of metabolic syndrome (MetS) according to the Sasang constitution (SC) and cold and heat pattern identification (CHPI). Methods: SC, CHPI, MetS, and component data were obtained from 2,561 participants in 26 Korean medical clinics from 2007 to 2013. SC, diagnosed by Korean medicine doctors, was confirmed by positive responses to herbal medicines administered according to that constitution. The CHPI was verified by a questionnaire about thermal sensitivity and drinking habits. The diagnosis criteria for MetS were: 1) waist circumference (WC) ≥90 cm (male) and ≥80 cm (female); 2) triglycerides ≥150 mg/dL; 3) high density lipoprotein cholesterol (HDL) <40 mg/dL (male) and <50 mg/dL (female); 4) blood pressure ≧130/85 mmHg; and 5) fasting blood glucose ≥100 mg/dL. Odds ratios (ORs) and differences in MetS and its components were compared using logistic regression and ANCOVA. Results: The MetS prevalence rates were 54.1%, 22.0%, and 33.3% for Taeeumin (TE), Soeumin (SE), and Soyangin (SY), respectively, and 30.5% and 44.5% for the cold and heat patterns, respectively. ANCOVA for MetS components showed significantly higher WC in TE than in SE or SY, and all components except HDL were higher in the heat pattern group than in the cold pattern group. Logistic regression for MetS prevalence showed a significant association between TE and the heat pattern group (OR=1.653) but not for non-TE and the cold pattern group. Conclusions: Considering SC and CHPI together may be more effective in managing MetS than considering SC alone.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.55-60
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• 2017

Objectives : This study was conducted to analysis correlation of pattern identification and body mass index (BMI) in obese adolescents. Methods : A total of 228 middle school students, 226 students were agreed and included study and two were excluded because of disagreement. It was conducted cold-heat pattern questionnaire, phlegm pattern questionnaire and after height and weight were measured. Firstly, out of 24 who did not respond to all of questionnaires. Secondary, out of 159 who are normal range on international obesity standard(BMI < $30kg/m^2$) Results : The average height and weight of 43 subjects was $159.65{\pm}9.45cm$, $70.10{\pm}8.47kg$ respectively. The average score of pattern identification was cold pattern score(CPS) was $2.70{\pm}1.61$, heat pattern score(HPS) was $3.30{\pm}1.99$, phlegm pattern score(PPS) was $3.95{\pm}5.02$. There was no significant correlation with BMI and CPS, HPS, PPS. Conclusions : In this study, there was no significant correlation of pattern identification and BMI in obese adolescents.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1226-1233
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• 2009

Common cold occurs frequently and occupies an important position in medical treatment however obvious treatment is not suggested. There has been no agreement of pattern identification for common cold in oriental medicine. The purpose of this study is to develop a standard instrument of pattern identification for common cold which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 9 oriental respiratory internal medicine professors of 11 oriental medical colleges nationwide. The experts attended 3 consultation meetings and discussed developing the instrument, and we also took professional advices by e-mail. The results were as follows; First, we divided the pattern identification of common cold into nine pattern: Wind-cold type, Wind-heat type, Contain summerheat type, Contain dampness type, Qi deficiency type, Blood deficiency type, Yang deficiency type, Yin deficiency type, Influenza. Second, we got the mean weights to each symptom of nine pattern identification which had been scored on a 5-point scale - ranging from 0 to 4 by the 9 experts. Third, we made out the Korean instrument of the pattern identification for common cold. It was composed self reporting questionnaire and researcher reporting questionnaire. Though this study is not proved about validity, reliability, the instrument of pattern identification for common cold is meaningful and expected to be applied to the subsequent research. And also, we hope to improve the instrument and make up for this study through various research and discussion.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.3
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• pp.367-375
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• 2012

The goal of current study is to make a standard pattern identification for post stroke depression using a delphi method. Finally, ten experts of oriental medicine, especially of stroke or depression, participated in Dephi examination. At the first meeting, experts conducted free discussion and determined to use the previous published questionnaires of Deficiency-Excess identification and Cold-Heat identification. From the second round, experts participated in evaluating and correcting the questionnaire by email. New seven questions were added to the questionnaire of Deficiency-Excess identification through the second round. Finally, the standard pattern identification of Cold-Heat or Deficiency-Excess is composed 20 questions and 11 questions, respectively. These pattern identifications for post stroke depression will contribute to research and treatment of oriental medicine.