• 한국보건간호학회지
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• 제12권2호
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• pp.89-106
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• 1998

The Health Promotion Model by Pender(l987) was used as the conceptual framework for analyzing the health promotion behaviors. The purposes of this study were to describe health promoting life style behaviors in 245 women between the ages of 35 and 59 living in Seoul and other cities and to find their predictive factors. Data were collected from 1st to 23th. June. 1998. The tool used for this study was structured questionnaire with consisted of 8 items on general characteristics. 5 items on health related characteristics. 43 items on health promoting life style. 28 items on menopausal symptoms. 5 items on family support. and 28 items on self-efficacy. The collected data were analyzed using the SAS. yielding descriptive statistics. ANOVA. Pearson's Correlation. stepwise multiple regression. The findings of this study are as follows. 1) The mean score of health promotion behavior(3.25) is not high. The mean scores of this self actualization (3.73). interpersonal support (3.68). and nutrition (3.57). regulation of stress (3.22) in domains are higher than health responsibility (2.90). exercise (2.63). 2) The results of the comparison between the health promotion behaviors and general variables showed a statistically significant difference in education (P=.0061), domestic economy status(P=.0001). perception of health status(P=.0001) but. age. state of menstruation. perception of weight is not significant difference. 3) The correlation between health promoting life style and self-efficacy(P=.0001). family support(P=.0001) is significant. But. there is no correlation between health promoting life style and age. number of family. perception of weight. 4) In the cognitive-perceptual factors. self-efficacy (P=.0001) is very significant predictor (accounted for $39.7\%$) and in the modifying factors. family support(P=.0001) is very significant (accounted for $9.0\%$). It is same to other research results.

• 동의생리병리학회지
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• 제25권1호
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• pp.37-47
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• 2011

This study was aimed to investigate the memory enhancing effect of Jeongjihwan against scopolamine-induced amnesia in C57BL/6 mice. To determine the effect of Jeongjihwan on the memory and cognitive function, we have injected scopolamine (1 mg/kg, i.p.) into C57BL/6 mice 30 min before beginning of behavior tests. We have conducted Y-maze, Morris water-maze, passive avoidance and fear conditioning tests to compare learning and memory functions. Scopolamine-induced behavior changes of memory impairment were significantly restored by oral administration of Jeongjihwan (100 or 200 mg/kg/day). To elucidate the molecular mechanism underlying the memory enhancing effect of Jeongjihwan, we have examined the antioxidant defense system and neurotrophic factors. Jeongjihwan treatment attenuated intracellular accumulation of reactive oxygen species and up-regulated mRNA and protein expression of antioxidant enzymes as assessed by RT-PCR and western blot analysis, respectively. Jeongjihwan also increased protein levels of brain-derived neurotrophic factor (BDNF) compared with those in the scopolamine-treated group. Furthermore, as an upstream regulator, the activation of cAMP response element-binding protein (CREB) via phosphorylation was assessed by Western blot analysis. Jeongjihwan elevated the phosphorylation of CREB (p-CREB), which seemed to be mediated partly by extracellular signal-regulated kinase1/2 (ERK1/2) and protein kinase B/Akt. These findings suggest that Jeongjihwan may have preventive and therapeutic potential in the management of amnesia.

• 대한불안의학회지
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• 제2권2호
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• pp.101-107
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• 2006

Object : Since autonomic nerve system dysfunction was known as the mechanism of panic disorder, many researchers used heart rate variability (HRV) as means of measuring autonomic nerve function of patients with panic disorder. We aimed to examine the effect of paroxetine medication for 3 months on symptom improvement and change of heart rate variability of the patients with panic disorder. Methods : The subjects were patients with panic disorder who visited the psychiatric outpatient clinic of Samsung Medical Center in Seoul. We included panic disorder patients who were aged from 20 to 50 and in normal BMI range (from 18 to 30) to minimize the effect of age and weight on HRV data. We excluded the patients with EKG abnormalities, hypertension or other major psychiatric disorders. They took 20-40 mg paroxetine medication a day for 3 months. Alprazolam was used only during the first month to control the acute panic symptoms and was tapered off after that. We measured the acute panic inventory (API), Hamilton rating scale for anxiety and depression (HAM-A & HAM-D), Spielberger state-trait anxiety inventory (STAIS, STAIT), and Beck depression inventory (BDI) in order to assess clinical improvement of the patients. And we measured time and frequency domain HRV in the resting, standing and cognitive stress states to assess the change of HRV. All measurements were done before and after paroxetine treatment. Result : After paroxetine medication, patients showed significant improvement in all psychiatric scales. In time domain of HRV, standard deviations of all R-R intervals (SDNN) were significantly increased in all states. In frequency domain of HRV, the ratio of high frequency to total power (HF/TP) in the standing state was significantly increased. Conclusion : After 3 months paroxetine medication, panic disorder patients showed significant clinical improvement and change in HRV data such as SDNN in all states and HF/TP ratio in the standing state. This result suggests that paroxetine medication is effective for the improvement of autonomic nerve system dysfunction in panic disorder patients.

• 한국지능시스템학회논문지
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• 제20권2호
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• pp.304-310
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• 2010

현대를 살아가는 현대인들이 경험하는 만성통증 및 디스크는 성인의 80% 이상이 경험하는 흔한 질병이다. 이러한 질환들 중 교통사고, 추락 등 물리적인 충격에 의한 발생율은 10%정도이며 대부분이 습관적으로 부적합한 자세를 취하게 되어 특정 부위에 지속적인 스트레스가 쌓여 발생하게 된다. 이처럼 부적합한 자세가 오랫동안 이어져 질환의 원인이 되는 것을 알면서도 고쳐지지 않는 이유는 지속적인 반복을 통한 습관화로 인하여 부적합한 자세를 바로 인지하지 못함으로써 바르게 교정하지 못하고 지속되어지기 때문이다. 따라서 본 시스템은 자세를 측정할 수 있는 센서들을 사용자에게 부착 후 사용자의 자세에 따른 데이터를 수집하여 정확한 자세를 측정하고 자세추정알고리즘을 이용하여 해당 자세의 적합여부를 추정한다. 사용자가 부적합한 자세를 지속적으로 취할 경우 이를 인지할 수 있도록 한다. 그리고 적합한 자세로 변경하도록 유도하여 부적합한 자세의 습관화를 방지하는데 목적을 두고 있다. 또한 부적합한 자세의 원인을 분석 후 제거하여 적합한 자세를 취하는데 보조자의 기능을 수행 한다. 정확한 측정을 통한 반복적인 인지 학습을 통해 올바른 자세를 습관화 한다면 성장기 어린이와 만성 질환자에게 많은 도움을 줄 것으로 생각 된다.

• 대한간호학회지
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• 제46권2호
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• pp.260-270
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• 2016

Purpose: This study was conducted to develop a program to help emergency nurses overcome compassion fatigue, and to analyze the effects of the program. Methods: A nonequivalent control group pretest-posttest design was used. There were 14 participants in the experimental group and 18 subjects in the control group. The program was comprised of five, weekly 80-minute sessions including understanding and assessment of compassion fatigue, enhancing positive affect, balancing work-life, planning self care, training in relaxation techniques and cognitive restructuring, and getting social support. Research variables were ego-resiliency, compassion satisfaction and compassion fatigue of the ProQOL 5, and salivary cortisol. Data were analyzed using Chi-square test, independent t-test, and paired t-test. Results: The first hypothesis, "There will be a difference in scores for ego resiliency between the experimental group and the control group". was not supported. The second hypothesis, "There will be a difference in scores for compassion satisfaction between the experimental group and the control group" was supported (t=2.15, p=.046). The third hypothesis, "There will be a difference in scores for compassion fatigue between the experimental group and the control group" was not supported. Conclusion: The first program for emergency nurses to overcome compassion fatigue in Korea was effective in increasing emergency nurses' compassion satisfaction and decreasing salivary cortisol level in the experimental group. Therefore, this program for overcoming compassion fatigue is useful to increase emergency nurses' compassion satisfaction. However replication studies of short-term intensive program reflecting emergency nurses' opinion are needed.

• 의학교육논단
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• 제12권1호
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• pp.9-22
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• 2010

It is the most important thing at present for physicians to posses the qualification of medical professionalism. A lot of medical schools have made all-out efforts to develop leaders of medicine, who will be able to meet the needs of medical professionalism in this complex medical environment. The purpose of this study is to review the cognitive base of medical professionalism leading the curriculum development of medical professionalism. The discussion of medical professionalism started in the 20th century. During the 1960s, there were attempts to reshape the concepts and attributes of medical professionalism. The government began to intervene in the autonomy of physician and the self regulation policy of medical society in 1970s. Physician may be asked to play as a healer and professional (what?) during their medical practice. The fundamental role of healer such as care, compassion, honesty, integrity, confidentiality, ethical behaviors, and respect with patients were nothing fresh to tell even though the age was changed. The attributes of professional which are physician's autonomy, self regulation, teamwork, and responsibility to society has been changed dramatically over the past five decades. In general, medical educators agreed that professionalism is demonstrated through a foundation of clinical competence, communication skills, and ethical and legal understanding, upon which is built application of the principles of professionalism: excellence, accountability, altruism, and humanism. If physicians fail to show professionalism in society, they will confront the crisis which can be under the government control. The only way to keep their autonomy is to practice medical professionalism. So far today, medical schools have laid more stress on competence than value standards in educational systems and it was restricted for medical students to learn the value standards for medical practice. To understand and practice the medical professionalism, it is the most realistic way to solve the complicated medical problems.

• 대한지역사회영양학회지
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• 제25권4호
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• pp.303-316
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• 2020

Objectives: The nutritional status of cancer patients undergoing chemotherapy is closely related to the compliance of nutrition education. However, as chemotherapy is conducted repeatedly, compliance with nutrition management is lowered, leading to malnutrition. Malnutrition is related directly to the quality of life after surgery in cancer patients. Therefore, this study examined the factors related to compliance with nutrition management during chemotherapy. Methods: In this study, five subjects with colorectal cancer undergoing adjuvant chemotherapy were interviewed in-depth using the Giorgi study method. The contents of the nutrition education visits and in-depth interviews were transcribed in the language of the subject after recording, and the appropriateness of the data was improved by reflecting the subject's actions and facial expressions. Results: After conducting the in-depth interviews for each subject, the experience of the subject's diet and adjuvant chemotherapy was drawn into two domains, six elements, and 26 sub-elements. In the cognitive domain, the patients experienced physical and psychological changes, and the need for nutrition management was recognized by analyzing the dietary causes of the diseases. In the domain of practice, a knowing-doing gap was formed, unlike the patient's will. Factors that inhibited compliance with nutritional management included digestive problems, sensory changes, loss of appetite, and social interaction stress. Conclusions: Dietary management is very important for patients receiving periodic anticancer therapy, and step-by-step training and personal monitoring based on the chemotherapy order is necessary to maintain the patient's will and social and environmental support.

• 한국전자통신학회논문지
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• 제14권2호
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• pp.397-404
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• 2019

본 연구는 아파트 경비원들을 중심으로 실시되고 있는 ICT직무교육과정을 개발하고 실제로 적용한 결과를 분석하였다. 아파트 민간경비종사자의 대다수가 노인인 점을 고려하여 노인의 컴퓨터에 대한 태도, 노인의 신체적 인지적 특성을 분석하여 노인교육을 위한 ICT직무 코스웨어를 설계하고 교육콘텐츠를 개발하였다. 교육프로그램을 실험집단에 적용하여 사전 사후 검사결과를 통해 만족도와 교육적 효과를 분석하였다. 분석결과 교육프로그램의 만족도는 전체적으로 평균 4.00점대 이상의 높은 만족도를 보였으며, 노인정보화 교육프로그램 정성적 평가 검사 도구를 활용해 교육프로그램 투입 전 후로 실험집단의 인터넷 자기 효능감, 인터넷 활용능력 향상, 인터넷 이용용도 인지, 개인정보화 의지, 생활교정, 세대 간 갈등해소, 자신감, 인터넷 스트레스 등이 통계적으로 유의미하게 상승했음을 확인하였다. 이러한 결과를 종합해 보면 본 연구에서 개발한 "민간경비 ICT직무교육" 교육프로그램이 노인정보화에 효과적이며 다른 노인교육 프로그램에 적용 및 촉진에 기여할 수 있을 것이다.

• Clinical Psychopharmacology and Neuroscience
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• 제16권4호
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• pp.422-433
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• 2018

Objective: Neuropsychiatric manifestations like depression and cognitive dysfunction commonly occur in inflammatory bowel disease (IBD). In the context of the brain-gut axis model, colitis can lead to alteration of brain function in a bottom-up manner. Here, the changes in the response of the hypothalamic-pituitary-adrenal axis and inflammation-related markers in the brain in colitis were studied. Methods: Dextran sodium sulfate (DSS) was used to generate a mouse model of colitis. Mice were treated with DSS for 3 or 7 days and sacrificed. We analyzed the gene expression of brain-derived neurotrophic factor (BDNF), cyclooxygenase 2 (COX-2), and glial fibrillary acidic protein (GFAP), and the expression of GFAP, in the hippocampus, hypothalamus, and amygdala. Additionally, the levels of C-reactive protein (CRP) and serum cortisol/corticosterone were measured. Results: Alteration of inflammatory-related markers varied depending on the brain region and exposure time. In the hippocampus, COX-2 mRNA, GFAP mRNA, and GFAP expression were upregulated during exposure to DSS. However, in the hypothalamus, COX-2 mRNA was upregulated only 3 days after treatment. In the amygdala, BDNF and COX-2 mRNAs were downregulated. CRP and corticosterone expression increased with DSS treatment at day 7. Conclusion: IBD could lead to neuroinflammation in a bottom-up manner, and this effect varied according to brain region. Stress-related hormones and serum inflammatory markers, such as CRP, were upregulated from the third day of DSS treatment. Therefore, early and active intervention is required to prevent psychological and behavioral changes caused by IBD, and region-specific studies can help understand the precise mechanisms by which IBD affects the brain.

• Nuclear Engineering and Technology
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• 제53권2호
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• pp.657-665
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• 2021

Nondestructive evaluation methods play an important role in ensuring component integrity and safety in many industries. Operator fatigue can play a critical role in the reliability of such methods. This is important for inspecting high value assets or assets with a high consequence of failure, such as aerospace and nuclear components. Recent advances in convolution neural networks can support and automate these inspection efforts. This paper proposes using residual neural networks (ResNets) for real-time detection of corrosion, including iron oxide discoloration, pitting and stress corrosion cracking, in dry storage stainless steel canisters housing used nuclear fuel. The proposed approach crops nuclear canister images into smaller tiles, trains a ResNet on these tiles, and classifies images as corroded or intact using the per-image count of tiles predicted as corroded by the ResNet. The results demonstrate that such a deep learning approach allows to detect the locus of corrosion via smaller tiles, and at the same time to infer with high accuracy whether an image comes from a corroded canister. Thereby, the proposed approach holds promise to automate and speed up nuclear fuel canister inspections, to minimize inspection costs, and to partially replace human-conducted onsite inspections, thus reducing radiation doses to personnel.