• Journal of Korean Neurosurgical Society
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• v.63 no.2
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• pp.261-267
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• 2020

Objective : We investigated the effect of hypnotics on sleep quality, cognitive function, and depressive mood in patients with insomnia following brain tumor resection. Methods : From patients who underwent brain tumor resection, we recruited 10 patients with insomnia who received hypnotics for more than 1 week during a 3-week follow-up period (insomnia group). We also recruited 12 control patients with brain tumors but without insomnia (control group). We evaluated sleep quality at baseline and 3 weeks later using the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), the Stanford Sleepiness Scale (SSS), and the Epworth Sleepiness Scale (ESS) and investigated cognitive function and depression using the Computerized Neuropsychological Test and the Beck Depression Inventory (BDI). Results : At baseline, SSS, ISI, PSQI, and BDI scores were significantly higher and visual continuous performance test (VCPT) and auditory continuous performance test (ACPT) scores were significantly lower in the insomnia than in the control group. Three weeks later, the patients who had received hypnotics had significantly higher ISI, PSQI, ESS, VCPT, ACPT, visual span forward and backward, and visual recognition test scores, and significantly lower BDI scores. Conclusion : Quality of sleep in patients with insomnia following brain tumor resection was initially poor but improved significantly after taking hypnotic medication. Further, the hypnotic medications appeared to contribute to the amelioration of cognitive impairments and depressive moods in patients who previously underwent brain tumor resection. We thus recommend the use of hypnotics for patients with brain tumors with insomnia.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.4
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• pp.105-117
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• 2020

Objectives The objective of this study is to assess the effectiveness of electroacupuncture for patients with hip arthroplasty. Methods According to participants, intervention, comparison, outcome, study design, we searched for clinical studies that conducted electroacupuncture for patients with hip arthroplasty. Results Finally 11 randomized controlled trials were chosen for systemic review and meta-analysis. The frequently used evaluation tools were Incidence of postoperative cognitive dysfunction (POCD), heart rate, blood pressure. Almost studies showed electroacupuncture has effects for patients with hip arthroplasty. Through meta analysis, Electoacupuncture showed statistically significant effect of reducing the anesthetic dosage and incidence of postoperative psychonosema and adverse reactions in intra-operation period, reducing the incidence of POCD in peri-operation period, incidence of deep venous thrombosis in post-operation period. Conclusion 11 studies reported that electroacupuncture has significant effects on hip arthroplasty. But, many studies were assessed in a probable high risk of bias. And all studies published in one overseas country. So, it requires attention to comprehend this study. To make up for this limitaion, more well designed clinical research are needed.

• BMB Reports
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• v.55 no.10
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• pp.512-517
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• 2022

Traumatic brain injury (TBI) is brain damage which is caused by the impact of external mechanical forces. TBI can lead to the temporary or permanent impairment of physical and cognitive abilities, resulting in abnormal behavior. We recently observed that a single session of early exercise in animals with TBI improved their behavioral performance in the absence of other cognitive abnormalities. In the present study, we investigated the therapeutic effects of continuous exercise during the early stages of TBI in rats. We found that continuous low-intensity exercise in early-stage improves the locomotion recovery in the TBI of animal models; however, it does not significantly enhance short-term memory capabilities. Moreover, continuous early exercise not only reduces the protein expression of cerebral damage-related markers, such as Glial Fibrillary Acid Protein (GFAP), Neuron-Specific Enolase (NSE), S100β, Protein Gene Products 9.5 (PGP9.5), and Heat Shock Protein 70 (HSP70), but it also decreases the expression of apoptosis-related protein BAX and cleaved caspase 3. Furthermore, exercise training in animals with TBI decreases the microglia activation and the expression of inflammatory cytokines in the serum, such as CCL20, IL-13, IL-1α, and IL-1β. These findings thus demonstrate that early exercise therapy for TBI may be an effective strategy in improving physiological function, and that serum protein levels are useful biomarkers for the predicition of the effectiveness of early exercise therapy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.176-187
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• 2019

This study was conducted to investigate the levels of self-esteem, rehabilitation motivation and quality of life and to identify the influencing factors of quality of life in stroke patients who were receiving rehabilitation therapy. Data were collected from February 22 to March 20, 2016 using self-administered questionares and the data from 216 participants were analyzed using SPSS WIN 21.0 program(SPSS Inc., Chicago, IL, USA). The results of this study were as follows: the mean self-esteem was 3.09/5, rehabilitation motivation was 3.60/5, and quality of life was 2.95/5. Sex, age, education, caregiver, occupation, duration after attack, the degree of disability(dependence), and cognitive function were significantly associated with quality of life. There was positive correlation between quality of life and self-esteem(r=.45, p<.001) and there was positive correlation between quality of life and rehabilitation motivation(r=.27, p<.001). Variables such as self-esteem, duration after attack, the degree of disability(dependence), and cognitive function explained 43.6%(F=14.87 p=<.001) of the variance in quality of life in model 3. Consequently, it is needed to develop and apply nursing intervention and programs for improving self-esteem during rehabilitation in order to improve quality of life of stroke patients.

• Journal of Korean Academy of Medicine & Therapy Science
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• v.10 no.2
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• pp.59-71
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• 2018

Objective: The purpose of this study is to compare the effects of the CO-OP program using cognitive strategy on the satisfaction and high-level cognitive function of chronic stroke patients with cognitive impairment with the existing task-oriented approach training method. Method: The group randomly selects the experimental group and control group from 30 patients who suffer cognitive damage due to brain damage, and then randomly presents the Cognitive Orientation to daily Occupative Performance (CO-OP) Results: The results of the study showed a significant increase in patient performance and satisfaction, task performance, and high-level cognitive functions in comparison to those before training (p<).05) There was no significant difference in CNT testing in controls; Although there were no significant differences in overall CNT testing between the two groups, the COPM, AMPS tests showed a significant increase in the experimental group compared to the comparators (p <.05). Conclusion: The Cognitive Orientation to Daily Occupative Performance (CO-OP) Intervention Act, which uses meta-in strategies, was previously used. We were able to confirm that it could be a more effective intervention in task performance and high-level cognitive function than in the Meaningful Task-Specific Training Program (MTST).

• Journal of Industrial Convergence
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• v.19 no.5
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• pp.91-102
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• 2021

The purpose of this study was to systematically review about randomized controlled trials the characteristics and effect of cognitive function intervention for patient with dementia. We searched studies published from January 2010 to June 2021 in 5 databases. A total 1,104 studies were found and included 27 studies in final analysis. Methodological quality was assessment with the Cochrane's RoB(risk of bias) tool. Mini-Mental State Examination(MMSE) was the most used as the assessment tool for identifying the cognitive function. Cognitive function intervention were exercise, art, cognitive stimulation, reminiscence, music, multimodal cognitive rehabilitation, virtual reality, horticultural, computerized cognitive training, intentional snoezelen, beauty, cooking, korean traditional familiarity program. Most of the intervention except exercise 2, virtual reality 1, beauty 1 were effective in improving cognitive function. This study provided a clinical evidence for planning and implementing intervention for cognitive function intervention. In the future, various intervention studies suitable for the characteristics of dementia should be conducted by improving the quality of research methods.

• PNF and Movement
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• v.10 no.1
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• pp.25-33
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• 2012

Purpose : The purpose of this study was to compare the effect of treadmill training and cognitive task with in the course of treadmill training at the same time with chronic stroke patients. Methods : Fourteen chronic stroke patients participated. Participants were randomly assigned to the control and experimental group(7 experimental, 7 control). All of participants were in-patients at local hospital and had been receiving a traditional rehabilitation program, five days a week. The both groups have undergone 4weeks. The experimental group trained in treadmill and cognitive task at the same time, but control group trained only treadmill. 10m walking test, Timed Up & Go (TUG) test and 6 Minutes walking(6M walking) test to measure the walking speed, dynamic balance and waling endurance ability were carried out before and after the training. Results : The result of the study were as follow:10m walking test were significantly increased both groups(p<.01), but not significant between groups(p>.05). TUG test were significantly increased both groups(p<.001) and between groups(p<.01). 6M walking test were significantly increased both groups(p<.001), but not significant between groups(p>.05). Conclusion : Ahead of return to the community to patients with stroke, cognitive task with in the course of treadmill training at the same time was effective in improving the dynamic balance ability.

• PNF and Movement
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• v.21 no.1
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• pp.11-18
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• 2023

Purpose: This study aims to compare the effects of obstacle walking training combined with cognitive tasks on balance, gait, and activities of daily living in patients with stroke. Methods: A single-subject design was used, where one stroke patient participated. Obstacle walking training combined with cognitive tasks was performed for 1 hour per day for a total of 10 times during the intervention phase. The subjects were measured five times in the baseline phase, 10 times in the intervention phase, and five times in the follow-up phase. The outcome measurements included the Berg balance scale (BBS), the 10-meter walk test (10 MWT), and the Korean modified Barthel index (K-MBI). Results: In this study, the results showed that the 10 MWT scores during the intervention period improved and that this improvement remained, even during the post-period. In addition, BBS and K-MBI values for stroke patients increased significantly after training. Conclusion: The results of this study revealed that obstacle walking training combined with cognitive task training may be helpful to improve balance, gait, and activities of daily living in stroke patients. Therefore, obstacle walking training combined with cognitive tasks is recommended for stroke patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4798-4804
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• 2015

The aim of this study is evaluate the effect of a cognitive occupational therapy program on cognitive function, depression and hands function for patients with dementia living in a local community. A cognitive rehabilitation program of 10 weeks focusing on the occupational therapy is conducted from September to December 2012 on 21 patents (experimental group: 12, control group: 9) with dementia who are admitted to nursing homes in a metropolitan region. In the experimental group, the cognitive function, depression level, hand strength, and hand coordination ability is significantly improved after the application of the cognitive program (p<.05). In conclusion, the cognitive occupational therapy program may be a useful intervention for dementia. Because the therapeutic goal for dementia treatment is mainly concentrated on the amelioration of dementia symptoms, thus it is necessary to develop a various cognition training program that can be maintained the patient's residual functional capacity and returned to the social community through the early detection and the early intervention.

• Journal of the Korea Convergence Society
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• v.11 no.2
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• pp.37-43
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• 2020

The aim of this study was to examine the relationships between upper limb muscle strength and cognitive function in older Korean adults. A total of 130 Community-dwelling older adults, who were able to independently conduct activities of daily living, participated in the study. We assessed upper limb muscle strength using a handgrip strength and arm curl test, and their cognitive function using a Montreal cognitive assessment (MoCA) and general practitioner assessment of cognition (GPCOG) tests. Out of 130 participants, 26 (20%) had normal cognitive functions, while 104 older adults (80%) had mild cognitive impairments (MCI). Handgrip strength was significantly different between older adults with and without MCI (p<.05) and was related to MoCA and GPCOG (p<.05). In the result, there is a correlation between physical ability and cognitive function of the older adults. Therefore, it is necessary to develop exercise program to improve mental health.