• Korean Journal of Pharmacognosy
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• v.44 no.1
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• pp.41-46
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• 2013

Alzheimer's disease (AD), most common form of dementia is characterized that memory deficit and loss of cognitive function. The Codonopsis lanceolata (C.lanceolata) was treated by high hydrostatic pressure process and fermentation. This study was evaluated cognitive enhancing effect C.lanceolata extract by high hydrostatic pressure process and fermentation and compared with common C.lanceolata extract using Morris water maze and passive avoidance test. And their neuroprotective effect on glutamate induced oxidative stress in HT22 cell was investigated by MTT assay. High hydrostatic pressure process and fermented C.lanceolata extract (HFCE) and common C.lanceolata extract (CCE) (100 and 300 mg/kg) were administered to mice. Results showed HFCE enhanced cognitive function than CCE as shown by decrease in escape latency time. HFCE increased the latency time of the passive avoidance test compared to CCE. Furthermore, HFCE showed significant neuroprotective effect against glutamate cytotoxicity in HT22 cells. These results indicate that high hydrostatic pressure process and fermented more improve spatial cognitive ability of C. laanceolata.

• YAKHAK HOEJI
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• v.58 no.5
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• pp.287-293
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• 2014

Alzheimer's disease (AD), most common form of dementia is characterized that memory deficit and loss of cognitive function. This study was evaluated cognitive enhancing effect of water and ethanol extracts of Codonopsis lanceolata and compared using Morris water maze and passive avoidance test. The water and 70% ethanol extracts (100, 300 and 500 mg/kg) were administered to mice. The neuroprotective effect on glutamate-induced cell death in HT22 cells was additionally investigated using MTT assay. Results showed 70% ethanol extract of Codonopsis lanceolata enhanced cognitive function than water extract, as shown by decrease in escape latency time in Morris water maze test. In passive avoidance test, 70% ethanol extract also increased the latency time compared to the water extract. Furthermore, 70% ethanol extract significantly protected neuronal cell against glutamate cytotoxicity and showed higher than neuroprotective effect of water extract. These results indicate that 70% ethanol extract more improve spatial cognitive ability and protected neuronal cells than water extract.

• Journal of Convergence for Information Technology
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• v.10 no.9
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• pp.154-163
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• 2020

This study aimed to examine the speed of cognitive response of users by color application for the information searching or the searching how to use the target object. Also, the purpose of this study is to explore how color application has an impact on cognitive response, and to find the mediating effect of user's emotional response. A total of 227 persons were collected and analyzed by PASW 18.0 for data analysis. In conclusion, it was confirmed that color application had a direct effect on cognitive response, suggesting that emotional response may have a slight effect. Among four sub-factors of color applications, the most contribution factor of cognitive response was the clatiry and the lowest factor was the attention.

• Food Science of Animal Resources
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• v.43 no.4
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• pp.612-624
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• 2023

The gut-brain axis encompasses a bidirectional communication pathway between the gastrointestinal microbiota and the central nervous system. There is some evidence to suggest that probiotics may have a positive effect on cognitive function, but more research is needed before any definitive conclusions can be drawn. Inflammation-induced by lipopolysaccharide (LPS) may affect cognitive function. To confirm the effect of probiotics on oxidative stress induced by LPS, the relative expression of antioxidant factors was confirmed, and it was revealed that the administration of probiotics had a positive effect on the expression of antioxidant-related factors. After oral administration of probiotics to mice, an intentional inflammatory response was induced through LPS i.p., and the effect on cognition was confirmed by the Morris water maze test, nitric oxide (NO) assay, and interleukin (IL)-1β enzyme-linked immunosorbent assay performed. Experimental results, levels of NO and IL-1β in the blood of LPS i.p. mice were significantly decreased, and cognitive evaluation using the Morris water maze test showed significant values in the latency and target quadrant percentages in the group that received probiotics. This proves that intake of these probiotics improves cognitive impairment and memory loss through anti-inflammatory and antioxidant mechanisms.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.1-9
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• 2024

The purpose of this study was to identify the degree of academic stress, subjective happiness, and cognitive flexibility of nursing students, and to identify the mediating effect of cognitive flexibility between learning stress and subjective happiness. The subject of the study was 186 nursing students from a university in J City. The data collection period was from October 4 to October 23, 2023, and the data were analyzed using SPSS 23.0. The results of the study showed a significant correlation between academic stress, cognitive flexibility, and subjective happiness among nursing students, and it was found that cognitive flexibility partially mediated the relationship between academic stress and subjective happiness. Therefore, in order to improve the subjective well-being of nursing students, it is necessary to develop and apply programs that can reduce academic stress and increase cognitive flexibility.

• Osong Public Health and Research Perspectives
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• v.8 no.5
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• pp.308-317
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• 2017

Objectives: We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ${\geq}75$ years) adults. Methods: In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State Examination for Dementia Screening, whereas leisure activities were recorded via self-reporting of the extent and type of leisure activity the subjects involved in over the past year. Multivariate logistic regression was used to assess the effect of leisure activities on cognitive impairment, while controlling for potential covariates. Results: The subjects were more likely to participate in cognitive activities than in non-exercise physical activities. After controlling for selected covariates, involvement in cognitive activities was found to be a significant predictor of cognitive impairment in both the groups, whereas involvement in non-exercise physical activities was not a predictor of cognitive impairment in individuals aged ${\geq}75$ years. Moreover, depressive symptoms, rural residence, and hearing difficulties were common predictors of cognitive impairment among elderly-Korean-individuals. Conclusion: Leisure activity involvement may help delay cognitive impairment, which is often concomitant with aging. Hence, an early intervention service may significantly benefit both young-old and old-old individuals.

• Korean Journal of Child Studies
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• v.38 no.1
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• pp.217-231
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• 2017

Objective: The purpose of this study was to examine the influence of affective and cognitive empathy, and peer competence on behavioral problems among young children. Methods: The participants were 224 4- to 5-year-olds attending daycare centers in Gyeonggi-do. Children's empathy, peer competence, and behavioral problems were reported by their teachers. The collected data were analyzed using simple regression and three-step hierarchical multiple regression analyses. Results: The results showed that children who exhibited low affective empathy scored higher on peer acceptance and behavioral problems than children who had high affective empathy. This pattern of results was similarly found with cognitive empathy. Additionally, the effect of children's affective empathy on behavioral problems was fully mediated by peer competence, whereas the effect of children's cognitive empathy on behavioral problems was partially mediated by peer competence. Conclusion: These results suggest the need for peer-competence training based on affective empathy and training for both peer competence and cognitive empathy in reducing behavioral problems among young children.

• The Journal of Fisheries Business Administration
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• v.40 no.3
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• pp.51-68
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• 2009

The purpose of this study is to investigate the effect of Brand Personality to Marine Tourism Destination Images and Intention to Recommend. For this purpose, factor analysis was applied to 42 of J.Aaker's Brand Personality Scale and 5 personality dimensions were extracted. This analysis was also applied for cognitive and affective images and two of cognitive images and three of affective images were extracted. Multiple regression was done to estimate the relative effects of Brand Personality to both cognitive and affective images and intention to recommend. The results indicated brand personality influenced on both cognitive and affective images and intention to recommend directly and also found affective images was influenced by cognitive images. The results also suggested useful insight for future study. The Brand Personality Scale which developed for the product by Aaker might not be suitable for measuring the marine tourism destination brand personality and necessary to develop the new scale suitable for marine tourism destination personality, and be needed to study together with other moderating variance such as satisfaction and congruency with image to verifying the exact effect between different variables.

• Korean Journal of Applied Biomechanics
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• v.30 no.3
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• pp.265-273
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• 2020

Objective: The aim of this study was to investigate the effect of participation in contact sports on neurocognitive scores, dual-task walking velocity, and cognitive costs in retired athletes. Method: Forty-four retired athletes (mean age = 26.4±5.5 yrs) and thirty-eight controls (mean age = 26.1±4.9 yrs) participated in this study. Neurocognitive score was collected using computerized neurocognitive testing using RehaCom. Gait velocity was collected one single task, four dual-tasks, and two multi-tasks using Optogait. Mann-Whitney U test was performed to compared differences in cognitive scores among groups. A mixed-design two-way ANOVA and Bonferroni posthoc test were used to assess the effect of group and walking tasks for each condition. Results: The auditory divided attention of neurocognitive score of retired athletes was higher than the control group (p < 0.05). No statistical differences were observed in the other neurocognitive scores between groups. The changes in walking velocity and cognitive costs according to the dual-task walking tests differed between the two groups (p < 0.05). Conclusion: Although participation in contact sports did not affect the neurocognitive results of retired athletes, it could be confirmed that the reduction in walking velocity and an increase in cognitive costs during dual-task walking. Rather than observing only neurocognitive scores as a single evaluation item for cognitive evaluation of retired athletes in relation to daily life, the application of the dual-task gait test may provide useful information.

• Journal of International Academy of Physical Therapy Research
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• v.5 no.2
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• pp.714-717
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• 2014

The goal of this study was to assess the effect of a group exercise program on cognitive function of elderly people. Subjects were chosen to be elders with dementia having minor to moderate degrees of cognitive function. Study was started out by randomly dividing the 16 subjects into two groups, each with 8 people; the group exercise group and the control group. The group exercise group performed 8 weeks of group exercise program and general physiotherapy while the control group only performed general physiotherapy. Cognitive function was measured by Korean version mini-mental state examination. The study group's attention and calculation statistically significantly improved but the control group saw no statistically significant change. The group exercise program affected improvement in cognitive function of elderly people with dementia and in particular, was effective for enhancing their attention and calculation.