• Interdisciplinary Bio Central
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• v.1 no.2
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• pp.8.1-8.6
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• 2009

Introduction: It is a challenge to design a protein score function which stabilizes the native structures of many proteins simultaneously. The coarse-grained description of proteins to construct the pairwise-contact score function usually ignores the backbone directionality of protein structures. We propose a new two-body score function which stabilizes all native states of 1,006 proteins simultaneously. This two-body score function differs from the usual pairwise-contact functions in that it considers two adjacent amino acids at two ends of each peptide bond with the backbone directionality from the N-terminal to the C-terminal. The score is a corresponding propensity for a directional alignment of two adjacent amino acids with their local environments. Results and Discussion: We show that the construction of a directional adjacency-score function was achieved using 1,006 training proteins with the sequence homology less than 30%, which include all representatives of different protein classes. After parameterizing the local environments of amino acids into 9 categories depending on three secondary structures and three kinds of hydrophobicity of amino acids, the 32,400 adjacency-scores of amino acids could be determined by the perceptron learning and the protein threading. These could stabilize simultaneously all native folds of 1,006 training proteins. When these parameters are tested on the new distinct 382 proteins with the sequence homology less than 90%, 371 (97.1%) proteins could recognize their native folds. We also showed using these parameters that the retro sequence of the SH3 domain, the B domain of Staphylococcal protein A, and the B1 domain of Streptococcal protein G could not be stabilized to fold, which agrees with the experimental evidence.

• The Journal of the Petrological Society of Korea
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• v.6 no.1
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• pp.34-44
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• 1997

The Jurassic granites, commercially called Yangu stone in the Pocheon-Euijeongbu area, have generally compact and coarse-grained textures, which could be classified into two types; grey granite(Gg) and light pink granite(Gp). Specific gravity, absorption ratio and prosity of Gg and Gp in physical property are 2.64 and 2.61, 0.32 % and 0.44 %, 0.86% and 1.13 %, respectively. These higher values of two latters of Gp than those of Gg are due to the more abundant microcracks in Gp. Compressive strength og Gg than those of Gg are due to more abundant microcracks in Gp. Compressive strength og Gg and Gp are 1,726 kg/cm2 and 1,717 kg/cm, respectively and bestrength has a positive proportion with Qz+Af+Pl(quartz+alkali feldspar+plagioclase) modes without trending with Bt+Ac(biotite+accessories). Tensile strength has the positive proportions with Qz+Af+Pl and Bt+Ac. While Bt+Ac has a negative trend with abrasive hardness, Qz+A+Pl shows a positive one. These may suggest Qz+Af+Pl mainly affects on strenghts potentional dimension stone than Gp.

• Journal of the Korean earth science society
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• v.27 no.3
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• pp.328-340
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• 2006

In Janghwa-ri of Kanghwa Island morphological changes in four transects, 112 surface, and 2 core sediments were analyzed to understand the seasonal variation of the muddy tidal-flat environment. Sedimentary of facies can be classified into four facies; sand, muddy sand, sandy mud, and silt. During winter, the coarse-grained sediment facies expanded seaward. In the subsurface part of the core sediments, poorly sorted silty sediments dominate the area. According to the Pb-210 isotope analysis, accumulation rates of the tidal flat in Jangwha-ri appear to be $5{\sim}19mm/yr$. In the study area, the result is suggestive of a rapid change in depositional environments in recent years.

• Journal of the Korean earth science society
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• v.33 no.6
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• pp.497-509
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• 2012

The Gochanggun Kwangseungri macro-tide open-coast beach, located in the southwestern coast of Korea, was investigated in terms of the seasonal variations of surface sediment facies and sedimentary environment. Surface sediments of 45 sites in four seasons (May 2006 - February 2007) were sampled along three survey lines (15 sites in each survey line). The surface sediments of the Kwangseungri Beach are mainly composed of fine-grained sands, and its mean grain size is the coarsest in winter. Mud facies partly exists in summer, whereas it is nearly absent in winter. The spatial distribution of surface sediments shows a coast-parallel band of fine and medium sands during spring, fall, and winter. In the northern part, the study area is dominated by fine sands during summer, whereas by coarse sands during winter. These results can be interpreted that tide is more effective than wave on the surface sediment distribution of the Kwangseungri Beach during the summer season.

• Journal of Communications and Networks
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• v.10 no.4
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• pp.455-464
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• 2008

To provide network services consistently under various network failures, enterprise networks increasingly utilize path diversity through multi-homing. As a result, multi-homed non-transit autonomous systems become to surpass single-homed networks in number. In this paper, we address an inevitable problem that occurs when networks with multiple entry points deploy firewalls in their borders. The majority of today's firewalls use stateful inspection that exploits connection state for fine-grained control. However, stateful inspection has a topological restriction such that outgoing and incoming traffic of a connection should pass through a single firewall to execute desired packet filtering operation. Multi-homed networking environments suffer from this restriction and BGP policies provide only coarse control over communication paths. Due to these features and the characteristics of datagram routing, there exists a real possibility of asymmetric routing. This mismatch between the exit and entry firewalls for a connection causes connection establishment failures. In this paper, we formulate this phenomenon into a state-sharing problem among multiple fire walls under asymmetric routing condition. To solve this problem, we propose a stateful inspection protocol that requires very low processing and messaging overhead. Our protocol consists of the following two phases: 1) Generation of a TCP SYN cookie marked with the firewall identification number upon a SYN packet arrival, and 2) state sharing triggered by a SYN/ACK packet arrival in the absence of the trail of its initial SYN packet. We demonstrate that our protocol is scalable, robust, and simple enough to be deployed for high speed networks. It also transparently works under any client-server configurations. Last but not least, we present experimental results through a prototype implementation.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.6
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• pp.110-117
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• 2011

Seashore landfill projects use undersea pump dredging method for construction of airport and factory site. Coarse grain soil from the dredging is considered for use at inland. West sea shore bottom consists of primarily coarser grained silt-sand and this component contains far more percentage than is the case with East sea and South sea area. This soil shows very different characteristic at consolidation and compaction behavior. This research targets to utilize this type of dredging soil. Test specimen is from West sea (Saemangum) dredged soil landfill site. Model analysis is done for getting prediction of original soil relative density and N-value from dynamic compaction energy variance. Dynamic compaction energy is calculated for efficient foundation design.

• The KIPS Transactions:PartD
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• v.11D no.2
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• pp.407-414
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• 2004

The US DoD architecture framework defines architecture Products according to three viewpoints : operational view, system view, and technical view. But, its coarse-grained development process causes leakage of the details In transforming among different views. It also uses different methods for architecture products development, so that the levels of those products are not consistent. So. we propose MND AF(Ministry of National Defense Architecture Framework) for military environment to solve those problems. We propose additional architecture products to achieve consistency, including “architecture disciplines definition description,”“organization-to-activity relationships matrix,” “system definition description,” and “technical reference model,” etc. We also propose the architecture development process in more detail through seven steps. In addition, we propose the applicability of those products to the life cycle processes of the acquisition management. MND AF can provide consistency and traceability of architecture products, provide the basis for sl·stem integration and interoperability. Also, architecture developers can construct architecture in a more effective and efficient way through MND AF.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.2
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• pp.314-321
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• 1987

Post weld heat treatment (PWHT) of weldment of the low alloy Cr-Mo steel, in general, is carried out not only to remove residual stress and hydrogen existing in weldment but to improve fracture toughness of weld heat affected zone (HAZ). There occur some problems such as toughness decrement and stress relief cracking (SRC) in the coarse grained region of weld HAZ when PWHT is practiced. Especially, embrittlement of structure directly relates to the mode of fracture and is appeared as the difference of fracture surface such as grain boundary failure. Therefore, in this paper, the effect of heating rate on PWHT embrittlement under the various kinds of stresses simulated residual stress in weld HAZ was evaluated by COD fracture toughness test and observation of fracture surface. Fracture toughness of weld HAZ decreased with increment of heating rate under no stress, but it was improved to increment of heating rate under the stress. Grain boundary failure didn't almost appear at the heating rate of 600.deg.C/hr but it appeared from being the applied stress of 294 MPa at 220.deg.C/hr and 196 MPa at 60.deg.C/hr.

• Journal of The Geomorphological Association of Korea
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• v.20 no.4
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• pp.37-50
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• 2013

This study analyzes results of published studies of weathering pits in Korea focusing on tafoni and gnamma and it suggests new types of weathering pits and next subjects through the analysis. 34 papers, published between 1978 and February 2012, have been analyzed and the following are details of the analysis. In terms of the study results, weathering pits are commonly developed on coarse-grained rocks such as granite, but also found on various rocks. Multiple reasons including mechanical, chemical and salt weathering create weathering pits and they are closely related to the geological structure. Weathering pits are classified as tafoni and gnamma but the forms have not been verified. In the future, quantitative analysis must be conducted find the factors influencing creation, forms and development of weathering pits.

• The Journal of Engineering Geology
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• v.31 no.3
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• pp.257-267
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• 2021

Constraints on the structure and composition of the active layer are important for understanding permafrost evolution. Soil convection owing to repeated moisture-induced freeze-thaw cycles within the active layer promotes the formation of self-organized patterned ground. Here we present the results of ground penetrating radar (GPR) surveys across a selected sorted circle near King Sejong Station, Antarctica, to better delineate the active layer and its relation to the observed patterned ground structure. We acquire GPR data in both bistatic mode (common mid-points) for precise velocity constraints and monostatic mode (common-offset) for subsurface imaging. Reflections are derived from the active layer-permafrost boundary, organic layer-weathered soil boundary within the active layer, and frozen rock-fracture-filled ice boundary within the permafrost. The base of the imaged sorted circle possesses a convex-down shape in the central silty zone, which is typical for the pattern associated with convection-like soil motion within the active layer. The boundary between the central fine-silty domain and coarse-grained stone border is effectively identified in a radar amplitude contour at the assumed active layer depth, and is further examined in the frequency spectra of the near- and far-offset traces. The far-offset traces and the traces from the lower frequency components dominant on the far-offset traces would be associated with rapid absorption of higher frequency radiowave due to the voids in gravel-rich zone. The presented correlation strategies for analyzing very shallow, thin-layered GPR reflection data can potentially be applied to the various types of patterned ground, particularly for acquiring time-lapse imaging, when electric resistivity tomography is incorporated into the analysis.