• 한국전기화학회:학술대회논문집
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• 한국전기화학회 2003년도 추계총회 및 학술발표회
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• pp.23-23
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• 2003

• Bulletin of the Korean Chemical Society
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• 제34권11호
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• pp.3227-3232
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• 2013

A novel Cu-Co-O composite nanocatalyst was designed and prepared for the ozonation of phenol. A synergistic effect of copper and cobalt was observed over the Cu-Co-O composite nanocatalyst, which showed higher activity than either copper or cobalt oxide alone. In addition, the Cu-Co-O composite revealed good activity in a wide initial pH range (4.11-8.05) of water. The fine dispersion of cobalt on the surface of copper oxide boosted the interaction between catalyst and ozone, and the surface Lewis acid sites on the Cu-Co-O composite were determined as the active sites. The Raman spectroscopy also proved that the Cu-Co-O composite was quite sensitive to the ozone. The trivalent cobalt in the Cu-Co-O composite was proposed as the valid state.

• 한국수소및신에너지학회논문집
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• 제29권5호
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• pp.530-537
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• 2018

The effect of temperature and absorption capacity on heat of reaction, which is one of the characteristic studies of $CO_2$ absorption, were investigated in a differential reaction calorimeter (DRC) by using piperazine (PZ) and 2-methylpiperazine (2-MPZ). For all absorbents, $CO_2$ loading capacity decreased with increasing the temperature, while the heat of reaction increased, it figured out that these had a linear correlation between $CO_2$ loading capacity and/or heat of reaction and the temperature. The heat of reaction of all absorbents increased with increasing $CO_2$ loading capacity, especially 2-MPZ rapidly increased at $70^{\circ}C$. The reason for increase in the heat of reaction was occurred the regeneration of $CO_2$, which is a reverse-reaction, simultaneously with the absorption.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 D
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• pp.1639-1641
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• 1999

This paper deals with the seasonal variation of soil resistivity and the special characteristic for ground rods by lapse of time. The ground resistance was changed by humidity, temperature of earth and earth resistance. In this experiment, we studied the resistivity during the period from June 1995 to May 1996 by the soil and the corrosion of the ground rods. As a result, the soil resistivity during the period are appeared minimum in summer and maximum in winter. The loss in weight of Fe rod appeared higher than Cu, Al, Cu-Zn, and St. In the lapse of time, Fe rod was reduced 1.2 % later two years and 1.95 % later three years in weight. Cu rod was defected oxygens of 14.7 % later two years and 30.3 % later three years by EDX.

• 한국수정란이식학회지
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• 제29권1호
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• pp.1-5
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• 2014

Recent 2 decades, including in vitro maturation (IVM), assisted reproductive technologies (ARTs) achieved noteworthy development. However the efficiency of ARTs with in vitro matured oocytes is still lower than that with in vivo oocytes. To overcome those limitations, many researchers attempted to adapt co-culture system during IVM and consequently maturation efficiency has been increased. The beneficial effects of applying co-culture system is contemplated base on communication and interaction between various somatic cells and oocytes, achievement of paracrine factors, and spatial effects of extracellular matrix (ECM) from somatic cell surface. The understanding of co-culture system can provide some information to narrow the gap between in vitro and in vivo. Here we will review current studies about issues for understanding cu-culture system with various somatic cells to improve in vitro maturation microenvironment and provide bird view and strategies for further studies.

• Bulletin of the Korean Chemical Society
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• 제32권5호
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• pp.1650-1656
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• 2011

A series of potent tricyclic derivatives with a non-aromatic amide as potent PARP-1 inhibitors were successfully synthesized and their PARP-1 inhibitory activity was evaluated. Among the derivatives, 2-(1-propylpiperidin-4-yloxy)-7,8,9,10-tetrahydrophenanthridin-6(5H)-one 23c displayed potent activity in a PARP-1 enzymatic assay and cell-based assay ($IC_{50}$ = 0.142 ${\mu}M$, $ED_{50}$ = 0.90 ${\mu}M$) with good water solubility. Further, molecular modeling studies confirmed the obtained biological results.

• Molecular & Cellular Toxicology
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• 제2권3호
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• pp.170-175
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• 2006

The extensive isolation of genes responsive to stressful conditions from a soft coral Scleronephthya gracillimum was described. Soft coral colonies were exposed to thermal and chemical stressors to induce the expression of stress related genes. Differentially expressed genes by natural or anthropogenic stressors were identified by construction of standard and stress exposed-paired subtractive cDNA library. Thirty-two and thirty-seven kinds of candidate genes were identified from thermal or benzo[a]pyrene stress exposed group, respectively, which are associated with cell cycle, cell signaling, transcription, translation, protein metabolism, and other cellular functions. The expected function of each gene was described. The isolated and identified differentially expressed genes have a great potential to identify environmental stressors in global environmental changes and could act as molecular biomarkers for biological responses against environmental changes. Finally, it may open a new paradigm on soft coral health assessment.

• Journal of Pharmaceutical Investigation
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• 제40권6호
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• pp.379-386
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• 2010

Mono PEGylated rhG-CSF (PEG-G-CSF) prepared by utilizing unique PEG was purified and characterized by cation-exchange chromatography. A unique, trimer-structured PEG was chosen for PEGylation of rhG-CSF among various PEG moieties. The in-vitro bioactivity, stability, and pharmacokinetics of mono-PEG-G-CSF were examined and compared to those of native rhG-CSF. Mono PEG-G-CSF exhibited reduced in-vitro bioactivity to native rhG-CSF but showed an excellent in-vivo bioactivity and stability. Furthermore, it showed markedly reduced clearance in rats, thereby increasing the biological half-life by about 4.5-fold compared to that of native rhG-CSF. The results suggest that this unique, trimer-structured 23 kDa PEG can provide advantages to improve the bioactivity of therapeutic proteins in clinical use.

• Molecules and Cells
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• 제46권8호
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• pp.461-469
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• 2023

The tail of the striatum (TS) is located at the caudal end in the striatum. Recent studies have advanced our knowledge of the anatomy and function of the TS but also raised questions about the differences between rodent and primate TS. In this review, we compare the anatomy and function of the TS in rodent and primate brains. The primate TS is expanded more caudally during brain development in comparison with the rodent TS. Additionally, five sensory inputs from the cortex and thalamus converge in the rodent TS, but this convergence is not observed in the primate TS. The primate TS, including the caudate tail and putamen tail, primarily receives inputs from the visual areas, implying a specialized function in processing visual inputs for action generation. This anatomical difference leads to further discussion of cellular circuit models to comprehend how the primate brain processes a wider range of complex visual stimuli to produce habitual behavior as compared with the rodent brain. Examining these differences and considering possible neural models may provide better understanding of the anatomy and function of the primate TS.

• Korean Chemical Engineering Research
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• 제49권2호
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• pp.244-249
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• 2011

연소 후 $CO_{2}$ 포집기술이 적용된 500 MWe 석탄화력발전소의 경제성평가를 수행하고 $CO_{2}$ 저감비용(Cost of $CO_{2}$ avoided)을 산출하였다. 본 연구에서 고려된 $CO_{2}$ 포집기술은 이미 상업적으로 적용이 가능하고, 기존의 화력발전에 적용이 용이한 화학 흡수법을 기초로 하였으며 투자비용 산출을 위해 IEA Greenhouse Gas R&D Programme에서 제시하는 데이터를 활용하였다. 또한 $CO_{2}$ 포집공정 중 가장 많은 발전효율 저하를 가져오는 재열기(리보일러)에 투입되는 열에너지(재생에너지)를 대상으로 민감도분석을 수행하고 각각의 경우에서의 $CO_{2}$ 저감비용을 산출하였다. 분석결과 $CO_{2}$ 포집공정에 적용될 흡수제로 MEA(모노에탄올아민)가 사용되고 재생탑에서 필요한 재생에너지가 3.31 GJ/ton$CO_{2}$ 인 경우 발전효율은 $CO_{2}$ 포집설비 설치 전의 41.0에서 31.6%로 9.4% 감소하고 이때의 $CO_{2}$ 저감비용은 43.3 $/ton$CO_{2}$ 로 산출되었다. 그러나, 흡수제 재생에너지를 변수로 한 민감도분석에서 재생에너지가 2.0 GJ/ton$CO_{2}$로 낮아질 경우 $CO_{2}$ 저감비용은 36.7 $/ton$CO_{2}$까지 낮아질 것으로 분석되었다.