• 분석과학
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• 제8권4호
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• pp.511-517
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• 1995

A cationic water soluble porphyrin (5,10,15,20-tetrakis (l-methyl-pyridinium-4-yl)porphyrin, $H_2tmpyp^{4+}$) and its metalloporphyrins (MP) were easily extracted into acetonitrile separated by addition of sodium chloride ($4mol\;dm^{-3}$) in the presence of sodium perchlorate, where M denotes $Zn^{2+}$, $Cu^{2+}$, $Co^{3+}$, $Fe^{3+}$, and $Mn^{3+}$ and $P^{2-}$ is porphyrinate ion. The extracted ion-pair complexes were completely dissociated to $[MP(ClO_4)_3]^+$, and $[MP(ClO_4)_2]^{2+}$. The extraction and the dissociation constants were determined by taking into account of the partition constant of sodium perchlorate ($K_D=1.82{\pm}0.01$). The chemical properties of the separated acetonitrile phase as $E_{T(30)}$ and $D_{II,I}$ were determined and compared with other water miscible solvents (acetone, actonitrile, 1,4-dioxane, tetrahydrofuran, 1-propanol and 2-propanol). Furthermore, a sensitive and selective method was proposed for the determination of a subnanogram amount of copper(II) in natural water samples by using the present salting-out method and the porphyrins.

• 대한수의학회지
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• 제34권1호
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• pp.181-188
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• 1994

In 60 dairy cows with inactive ovaries, follicular cyst, luteal cyst, persistent corpus luteum and silent heat as diagnosed by rectal palpation, and those that had not resumed ovarian cycles until 60 days postpartum, progesterone concentrations for differential diagnosis of reproductive disorders were measured and were compared in matched plasma, skim milk and milk fat samples at 10 days interval. The incidence rate of reproductive disorders were as follows; inactive ovaries 20(33.3%), silent heat 11(18.3%), follicular cyst 7(11.7%), luteal cyst 7(11.7%), persistent corpus luteum 7(11.7%), pyometra 4(6.7%), vaginitis 2(3.3%), cystic corpus luteum 1(1.7%), and endometritis 1(1.7%), respectively. Cows having a progesterone concentration in plasma and skim milk < 1.0 ng/ml, and in milk fat < 80.0 ng/ml were considered to have inactive ovaries or follicular cyst. Those with concentrations in plasma and skim milk ${\geq}1.0ng/ml$, and in milk fat ${\geq}80.0ng/ml$ were regarded as the cases of luteal cyst or persistent corpus luteum. Progesterone concentrations in above cows did not differ significantly between the time of initial determination and the 10 days after initial determination. But progesterone concentrations in cows with silent heat did differ significantly between the time of initial determination and the 10 days after initial determination(P<0.05). The accuracy of rectal palpation for making a differential diagnosis of ovarian dysfunction, as defined on basis of progesterone concentrations, were as follows; follicular cyst 55.6%, luteal cyst 50.0%, inactive ovaries 90.5% and persistent corpus luteum 60.0%, respectively. It may be concluded that progesterone determinations at 10 days interval is practical as an aid to diagnosing ovarian dysfunction, particularly follicular cyst and luteal cyst.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.224.1-224.1
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• 2003

A sensitive and selective liquid chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) was developed for the determination of beraprost in human plasma. Plasma samples were transferred into 96-well OASIS HLB extraction plate using an automated sample handling system and the drugs were eluted with methanol. The eluents were then evaporated and reconstituted with water. All sample transfer and solid-phase extraction (SPE) was automated through the application of both the PerkinElmer MultiPROBE II HT and TOMTEC Quadra 96 workstation. (omitted)

• 한국해양학회지
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• 제4권1호
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• pp.9-16
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• 1969

금번 국내최대의 포항종합제철공장의 건립에 즈으하여 국내최대의 새로운 항만이 영일만내에 건설되고 있다. 항만의 건설의 외곽시설인 방파제 방사제 및 항입구의 배치계획에 기초자료가 된느 여러 조사업무중의 하나로 당 해역의 표사의 이동에 대한 조사가 실시되었다. 항만건설해역은 형산강과 냉천 사이의 해역으로써 이들 하천으로 부터의 유사가 표사이동에 미치는 영양도 아울러 조사되었으며, 표사의 공급원, 표사의 이동방향을 알기 위하여 광범위한 해역에 걸쳐 조사가 진행되었다. 표사는 해안을 따라 어떤 폭을 갖은 해변에서 발생하는 저질의 이동현상을 말하며, 하천의 유사와 마찬가지로 유체에 의한 물질의 운반작용이지만 그 운반기구는 하천의 유사에 비하여 대단히 복잡하여서 그의 정확한 선택파악은 대단히 어려운 문제이다. 최근 이와 같은 조사에 방사성물질이 추적자로 사용되고 있으며, 종래 사용되던 간접적인 방법에 비하여 비교적 간단히 그리고 직접적으로 표사의 실태를 파악할 수 있으미 확인되고 있다. 금번 조사에서는 방사성 추적자로서 Co-60을 사용하였다.

• 대한화학회지
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• 제54권5호
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• pp.541-550
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• 2010

새로운 일곱 자리 질소-산소($N_4O_3$)계 리간드 N,N'-Bis(2-hydroxybenzyl)-1,3-bis[(2-aminoethyl)amino]-2-propanol(H-BAP 4HCl)를 합성하였다. H-BAP 4HCl의 페놀 수산기의 para위치에 브롬, 염소, 메톡 시기 및 메틸기를 가진 Br-BAP 4HCl, Cl-BAP 4HCl, $CH_3O$-BAP 4HCl 및 $CH_3$-BAP 4HCl 염산염을 합성 하였다. 각 리간드의 화학구조는 C, H, N 원소분석법, $^1H$-NMR 및 $^{13}C$-NMR 분광법, 적외선 분광법 및 질량분석법을 통하여 확인하였다. 합성된 $N_4O_3$계 리간드의 전위차 적정 법을 이용하여 계산된 양성자 단계 해리상수는 여섯 단계의 해리상수(${\logK_n}^H$)값을 나타내었고, 각 리간드의 양성자 총괄 해리상수($log{\beta}_p$) 값은 Br-BAP < Cl-BAP < H-BAP < $CH_3O$-BAP < $CH_3$-BAP의 순서로 para Hammett 치환기상수($\sigma_p$) 값의 순서와 역순으로 잘 일치하였다. 각 리간드들과 전이금속(II) 이온들의 착물 안정도상수($logK_{ML}$) 값의 크기순서는 Co(II) < Ni(II) < Cu(II) > Zn(II) > Cd(II) > Pb(II)로 나타났다. 이때 각 리간드들과 전이금속(II) 이온들의 착물 안정도상수 값은 리간드의 총괄 해리상수 값의 크기순서와 같은 경향을 나타내었다.

• International Journal of Naval Architecture and Ocean Engineering
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• 제8권4호
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• pp.301-311
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• 2016

This paper describes the whole procedures to determine ice-induced global loads on the ship using measured full-scale data in accordance with the method proposed by the Canadian Hydraulics Centre of the National Research Council of Canada. Ship motions of 6 degrees of freedom (dof) are found by processing the commercial sensor signals named Motion Pak II under the assumption of rigid body motion. Linear accelerations as well as angular rates were measured by Motion Pak II data. To eliminate the noise of the measured data and the staircase signals due to the resolution of the sensor, a band pass filter that passes frequencies between 0.001 and 0.6 Hz and cubic spline interpolation resampling had been applied. 6 dof motions were computed by the integrating and/or differentiating the filtered signals. Added mass and damping force of the ship had been computed by the 3-dimensional panel method under the assumption of zero frequency. Once the coefficients of hydrodynamic and hydrostatic data as well as all the 6 dof motion data had been obtained, global ice loads can be computed by solving the fully coupled 6 dof equations of motion. Full-scale data were acquired while the ARAON rammed old ice floes in the high Arctic. Estimated ice impact forces for two representative events showed 7e15 MN when ship operated in heavy ice conditions.

• 품질경영학회지
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• 제45권2호
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• pp.293-306
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• 2017

Purpose: In this study, an optimal design level of influencing factors on semiconductor polishing process was determined to minimize flexion of both sides on wafers. Methods: First, significant interactions are determined by the stepwise regression method. ANOVA analysis on SN ratio and mean of dependent variable are performed to draw mean adjustment factors. In addition, the optimal levels of mean adjustment factors are decided by comparing means of each level of mean adjustment factors. Results: As a result of ANOVA, a mean adjustment factor was determined as a width of formed flexion on the plate. The mean of the difference has the nearest to 0 in the case when the width of formed flexion has level 2 (4mm). Conclusion: Optimal design levels of semiconductor polishing process are determined as follows; (i) load applied to the wafer carrier has a level 1 (3psi), (ii) load applied to the wafer has a level 1(3psi), (iii) the amount of slurry supplied during polishing has a level 3 (300 co/min), (iv) the width of formed flexion on the plate has level 2 (4mm).

• Environmental Engineering Research
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• 제13권4호
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• pp.177-183
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• 2008

Ex-situ reductive dechlorination of carbon tetrachloride (CT) by iron sulfide in a batch reactor was characterized in this study. Reactor scaled-up by 3.5 L was used to investigate the effect of reductant concentration on removal efficiency and process optimization for ex-situ degradation. The experiment was conducted by using both liquid-phase and gas-phase volume at pH 8.5 in anaerobic condition. For 1 mM of initial CT concentration, the removal of the target compound was 98.9% at 6.0 g/L iron sulfide. Process optimization for ex-situ treatment was performed by checking the effect of transition metal and mixing time on synthesizing iron sulfide solution, and by determining of the regeneration time. The effect of Co(II) as transition metal was shown that the reaction rate was slightly improved but the improvement was not that outstanding. The result of determination on the regeneration time indicated that regenerating reductant capacity after $1^{st}$ treatment of target compound was needed. Due to the high removal rates of CT, ex-situ reductive dechlorination in batch reactor can be used for basic treatment for the chlorinated compounds.

• 대한화학회지
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• 제26권5호
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• pp.320-325
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• 1982

황을 분석하기 위하여 준비한 용액을 이용하여 황화광석중 철, 구리, 코발트를 X-선 형광법으로 정량하였다. 시료를 $Br_2$ 와 $HNO_3$의 혼합용액으로 녹인 다음 HF로 처리하여 주성분인 $SiO_2$를 제거한 다음 용액으로 만들었다. 분석결과는 철함량이 20 ~ 50%에서 ${\pm}$1.5%, 구리 함량이 10 ~ 15%에서 ${\pm}$1.0%, 코발트함량이 1 ~ 5% 범위에서 ${\pm}$0.4% 이내로 다른 습식분석법의 data와 일치하고 있으며 재현성에 있어서도 좋은 결과를 얻었다.

• 대한조선학회논문집
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• 제48권4호
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• pp.325-329
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• 2011

Floating, production, storage and offloading (FPSO) is a production facility that refines and saves the drilled crude oil from a drilling facility in the ocean. The flare system in the FPSO is a major part of the pressure relieving system for hydrocarbon processing plants. The flare system consists of a number of pipes and complicated connection systems. Decision of pipe support types is important since the load on the support and the stress in the pipe are influenced by the pipe support type. In this study, we optimally determined the pipe support types that minimized the support cost while satisfying the design constraints on maximum support load, maximum nozzle load and maximum pipe stress ratio. Performance indices included in the design constraints for a specified design were evaluated by pipe structural analysis using CAESAR II. Since pipe support types were all discrete design variables, an evolutionary algorithm (EA) was used as an optimizer. We successfully obtained the optimal solution that reduced the support cost by 27.2% compared to the initial support cost while all the design requirements were satisfied.