• 제목/요약/키워드: Clinical safety

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Safe clinical photography: best practice guidelines for risk management and mitigation

  • Chandawarkar, Rajiv;Nadkarni, Prakash
    • Archives of Plastic Surgery
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    • 제48권3호
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    • pp.295-304
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    • 2021
  • Clinical photography is an essential component of patient care in plastic surgery. The use of unsecured smartphone cameras, digital cameras, social media, instant messaging, and commercially available cloud-based storage devices threatens patients' data safety. This paper Identifies potential risks of clinical photography and heightens awareness of safe clinical photography. Specifically, we evaluated existing risk-mitigation strategies globally, comparing them to industry standards in similar settings, and formulated a framework for developing a risk-mitigation plan for avoiding data breaches by identifying the safest methods of picture taking, transfer to storage, retrieval, and use, both within and outside the organization. Since threats evolve constantly, the framework must evolve too. Based on a literature search of both PubMed and the web (via Google) with key phrases and child terms (for PubMed), the risks and consequences of data breaches in individual processes in clinical photography are identified. Current clinical-photography practices are described. Lastly, we evaluate current risk mitigation strategies for clinical photography by examining guidelines from professional organizations, governmental agencies, and non-healthcare industries. Combining lessons learned from the steps above into a comprehensive framework that could contribute to national/international guidelines on safe clinical photography, we provide recommendations for best practice guidelines. It is imperative that best practice guidelines for the simple, safe, and secure capture, transfer, storage, and retrieval of clinical photographs be co-developed through cooperative efforts between providers, hospital administrators, clinical informaticians, IT governance structures, and national professional organizations. This would significantly safeguard patient data security and provide the privacy that patients deserve and expect.

Pemetrexed is Mildly Active with Good Tolerability in Treating Patients with Gastric Cancer

  • Lan, Hai;Lin, Cong-Yao;Li, Yan
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권17호
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    • pp.7137-7139
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    • 2014
  • Background: This systemic analysis was conducted to evaluate the efficacy and safety of pemetrexed based chemotherapy in treating patients with metastatic gastric cancer (MGC) as a salvage chemotherapy. Methods: Clinical studies evaluating the efficacy and safety of pemetrexed based regimens on response and safety for patients with gastric cancer were identified by using a predefined search strategy. Pooled response rates (RRs) of treatment were calculated. Results: In pemetrexed based regimens, 4 clinical studies including 171 patients with advanced gastric cancer were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 25.1% (43/171) in pemetrexed based regimens. Major adverse effects were neutropenia, anorexia, fatigue, and anemia. No treatment related death occurred in pemetrexed based treatment. Conclusion: This systemic analysis suggests that pemetrexed based regimens are associated with mild activity with good tolerability in treating patients with MGC.

Current Clinical Evidence for Korean Red Ginseng in Management of Diabetes and Vascular Disease: A Toronto's Ginseng Clinical Testing Program

  • Vuksan, Vladimir;Sievenpipper, John;Jovanovski, Elena;Jenkins, Alexandra L.
    • Journal of Ginseng Research
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    • 제34권4호
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    • pp.264-273
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    • 2010
  • While ginseng is reported to have a wide array of applications, there is growing evidence for its indications in diabetes and vascular disease. A clear connection, however, has not been established between ginseng's composition, dose and its targeted efficacy in humans. We therefore developed and initiated the Korean Red Ginseng Clinical Testing Program for diabetes and vascular function which is an efficacy and safety-based clinical screening model for ginseng. The most efficacious sources, ginsenoside profiles, doses, and modes of administration were examined in sequential, acute, followed by long term, randomized-controlled trials to investigate the efficacy and safety profiles. This review discusses the current state of the clinical research of Korean red ginseng program conducted in Toronto, paving the way for the use of clinically selected ginseng and its ginsenoside fractions in the management of diabetes and vascular diseases.

Safety, High Quality, Confidence of Kaneka CoQ10

  • Fujii, Kenji
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2006년도 Proceedings of The Convention
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    • pp.139-145
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    • 2006
  • Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200 mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, 45, 282 - 288).

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Safety, High Quality, Confidence of Kaneka CoQ10

  • Fujii, Kenji
    • 한국약용작물학회:학술대회논문집
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    • 한국약용작물학회 2006년도 Proceedings of The Convention of The Korean Society of Applied Pharmacology
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    • pp.139-145
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    • 2006
  • Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, $\underline{45}$, 282 - 288).

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간호사의 근로환경 개선을 위한 환자안전문화의 체계적 문헌 분석 (A Systematic Review of Clinical Nurses' Patient Safety Culture for Improving Nursing Work Environment)

  • 김종경
    • 한국직업건강간호학회지
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    • 제23권2호
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    • pp.67-79
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    • 2014
  • Purpose: The purpose of this study was to review the articles and theses on the patient safety culture of clinical nurses for identifying overall research trends regarding patient safety culture among hospital nurses, and to suggest strategies for improving nursing work environment related to patient safety culture. Methods: The subjects for this study were 17 articles selected according to inclusion criteria from five databases in Korea. Results: Seven articles were collected from nursing journals and ten from master's theses. The studies on the 17 articles were conducted at 66 hospitals from seven regions of Korea. The tools for patient safety culture were selected among the three tools from AHRQ and two Korean translation tools. The mean score of patient safety culture was 3.43. Conclusion: The findings from the article review indicate that, in order to improve nursing work environment for patient safety culture, the hospital and nursing manager should emphasize the education for patient safety, communication and open-minded reporting, and cooperation among the departments of hospital.

혈액투석실 간호사의 전문직관, 조직의사소통이 환자안전문화에 미치는 영향 (Influence of Professionalism and Organizational Communication on Patient Safety Culture of Nurses in Hemodialysis Units)

  • 정수진;정정희
    • 임상간호연구
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    • 제25권1호
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    • pp.98-105
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    • 2019
  • Purpose: The study was conducted to investigate correlation between professionalism, organizational communication the and patient safety culture of nurses in hemodialysis units and verify factors that affect patient safety culture. Methods: Data were collected from 109 nurses working in hemodialysis units located in Seoul and Gyeonggi-do. collected data were analyzed using descriptive statistics including t-test, one-way ANOVA, Pearson correlation coefficient and stepwise multiple regression with the SPSS 21.0 program. Results: The Professionalism of participants was significantly correlated with patient safety culture while the Organizational communication was also correlated with patient safety culture. Factors influencing participants' patient safety culture included professionalism, organizational communication, employment history in current hospital, and the number of patients per nurse. These factors explained 57.8% of patient safety culture. Conclusion: The research findings suggest that in order to increase the awareness of patient safety culture of nurses in hemodialysis units, strategic efforts are needed to enhance professionalism and organizational communication satisfaction of nurses in hemodialysis units.