• Title/Summary/Keyword: Clinical profile

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Multi-Phasic Mental Health Characteristics according to Harm-Avoidance and Self-Directedness Profile of Cloninger's Biopsychosocial Model (클로닌저의 생리심리사회 모델에서 위험회피-자율성 프로파일에 따른 다면적 정신건강 특성)

  • Chae, Han;Lee, Soo Jin
    • Journal of Oriental Neuropsychiatry
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    • v.33 no.3
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    • pp.259-266
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    • 2022
  • Objectives: The combination of Harm-Avoidance (HA) and Self-Directedness (SD) of Temperament and Character Inventory (TCI) has been reported pivotal for mental health; however its clinical usefulness in integrative medicine has not sufficiently reported. The purpose of this study was to illustrate multi-phasic mental health of subjective satisfaction with life, emotional well-being, and psychopathology, following the HA-SD profile groups. Methods: A total of 527 Korean university students reported HA and SD scores as to render their HA-SD profile, and multi-phasic mental health characteristics using Satisfaction with Life Scale (SWLS), Positive Affect and Negative Affect Schedule (PANAS), and Beck Depression Inventory (BDI) with composite well-being scales of SC (Sum of Self-Directedness and Cooperativeness score) and HI (Happiness Index, subtraction of Negative Affect (NA) score from Positive Affect (PA) score) as standardized. Pearson's correlation was used to report correlation coefficient, and the ANCOVA with age and sex as covariates, to show significant differences in mental health and well-being between the HA-SD profile groups. Results: The HA-SD profile groups showed distinctive multi-phasic mental health characteristics; health related scores of SWLS, PA, SC and HI decreased following the order of hS (low HA and high SD), HS (high HA and high SD), hs (low HA and low SD) and Hs (high HA and low SD) profile groups; however the non-health related scores of NA and BDI showed contrasting order. Conclusions: The HA-SD profile was found to be clinically useful for examining multi-phasic mental health and well-being status, and the TCI may be an imperative personality inventory for integrative medicine.

PHR Profiling System Based on FHIR (FHIR 기반 개인건강기록 프로파일링 시스템 개발방법)

  • Kim, Young Sik;Kim, Il Kon
    • KIPS Transactions on Software and Data Engineering
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    • v.4 no.7
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    • pp.277-282
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    • 2015
  • HL7 released V3 CDA(Clinical Document Architecture) and V2.x message standards for medical information exchange. Currently, these standards are successfully adopted by a number of nations across the globe. However, substantial amount of time is required to develop and implement these standards. Moreover, developers need a lot of time to understand these standards. To solve these issues from 2011, the HL7 standard framework started to discuss Fast Healthcare Interoperability Resources(FHIR) as next generation standard of healthcare information exchange. People's interests toward personal health record and smartphone penetration rate are growing and increasing rapidly. Therefore, our research team believes it is necessary to develop a PHR profiling system which could be accessed by using a smartphone and we developed the system. Through a FHIR Profile editor tool developed in Furore, we found that improvements could be made in generating and changing the profile. In order to build the PHR Profiling system, an Open-API on FHIR is used for exchanging information between electronic medical record system and PHR Profiling system. In the PHR Profiling system, the transactions of information between two systems are provided by RESTful service. In this study, we verify the efficiency of development of the PHR Profiling system through FHIR.

Multicomponent analysis of metabolites of low volatility in biological fluids by field ionization mass spectrometry

  • Kim, Kyoung-Rae;Anbar, Michael
    • Archives of Pharmacal Research
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    • v.7 no.1
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    • pp.23-31
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    • 1984
  • An improved mass spectrometric method for multicomponent analysis of metabolites in urine, well-suited for clinical biochemistry, is described. The method involves solvent elution of the metabolites from an adsorbent and the concentration of the eluate on a microadsorption column. This is administered by a direct inlet probe into the ionizing source of field ionization mass spectrometry (FIMS), which yield a molecular weight profile of the metabolites. The procedure provides rapidly (within one hour) reproducible profiles from a small volume of urine. The optimization of the sampling technique and the reproducibility are discussed.

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Durability of the Low Profile Ionescu-Shiley Valve in Aortic Position (이오네스큐 단고형 대동맥판의 내구성)

  • 김종환
    • Journal of Chest Surgery
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    • v.25 no.10
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    • pp.1041-1047
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    • 1992
  • The consecutive 35 patients underwent isolated aortic valve replacement with the low-profile model of the Ionescu-Shiley pericardial xenograft valve from 1984 to 1991. Operative mortality was 2.9%, and early survivors were followed up for a total 136.1 patient-years[Mean$\pm$SD, 4.00$\pm$2.14 years]. The linearized late mortality was 2.204% /pt-yr. Three patients required rereplacement of the valve with overall valve failure rate of 2.204% /pt-yr: two for endocarditis and one for paravalvular leak. There was no case of primary tissue failure. The linearized annual rates of complication were: thromboembolism 0.735% /pt-yr, bleeding 0.735%pt-yr, and endocarditis 2.204% /pt-yr. The actuarial survival at 8 years of follow-up was 90.4$\pm$5.3%, and the probabilities of freedom from thromboembolism and from rereplacement were 95.6$\pm$4.4% and 88.2$\pm$6.7% at 8 years respectively. Although the low profile Ionescu-Shiley pericardial valve provided favorable clinical performance comparable with the standard model up to 8 years, it needs prolonged follow-up to assess the pattern of its durability.

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Effects of phylloquinone supplementation on lipid profile in women with rheumatoid arthritis: a double blind placebo controlled study

  • Kolahi, Sousan;Gargari, Bahram Pourghassem;Abbasi, Mehran Mesgari;Jafarabadi, Mohammad Asghari;Shishavan, Neda Ghamarzad
    • Nutrition Research and Practice
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    • v.9 no.2
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    • pp.186-191
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    • 2015
  • BACKGROUND/OBJECTIVES: Rheumatoid arthritis (RA) is associated with an excess mortality from cardiovascular disease which is likely attributed to an atherogenic lipid profile. Among nutritional factors vitamin K has been recently focused as a pivotal nutrient in improvement of lipid related markers. Thus, this study was designed to determine the effects of vitamin K on lipid profile in this disease. SUBJECTS/METHODS: Fifty eight patients with definitive RA were participated in the present double blind placebo controlled study. They were randomly allocated into two groups to receive vitamin $K_1$ as phylloquinone [10 mg/day] (n = 30) or placebo pills (n = 28), for eight weeks. In order to control the effects of probable confounders dietary intakes, anthropometric measurements including weight and height, clinical status using disease activity score-28 (DAS-28), physical activity and anxiety status were evaluated at baseline. Moreover, serum levels of lipid related markers including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) were measured at baseline and at the end of intervention. RESULTS: There were no significant differences between the two groups regarding any of the baseline characteristics. After adjusting for some relevant confounders, in comparison between two groups, we observed no significant changes in lipid related markers at the end of intervention. Also, there was no significant difference between before and after intervention values within groups (P > 0.05). CONCLUSIONS: Function of vitamin $K_1$ in lipid profile modification remains still controversial. This study showed that vitamin $K_1$ has no effect on lipid profile in women with rheumatoid arthritis. Further studies with a longer follow-up are required to determine the effects of vitamin K on atherogenic lipid profile.

Clinical Study on Personality Characteristics of the Alcoholic Patients -with MMPI & Sasang Constitution(四象體質)- (알콜리즘 환자(患者)의 인격특성(人格特性)에 관(關)한 임상적(臨床的) 고찰(考察) -MMPI와 사상체질(四象體質)을 중심(中心)으로-)

  • Kim Jong-U;Kim Ji-Hyeok;Hwang Ui-Wan
    • Journal of Oriental Neuropsychiatry
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    • v.3 no.2
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    • pp.65-85
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    • 1992
  • To study the personality characteristics of alcoholic patients, they were screned with the MAST(Michigan Alcoholism Screening Test) and administered with the MMPI (Minnesota Multiphasic Personality Inventory) in the Dept. of Neuropsychiatry, Oriental Medical Hospital in Kyung Hee Univ. form March 1991 to June 1991. Patients admitted for alcoholism were examined and analyzed using the above tests and then studied by Sasang Constitutional approach. Results were as follows; 1. In the MAST score, the cases of obvious alcohol dependence was 53.3% and overall mean score was 28.1 point. 2. In the MMPI scale, the mean of the T-scores for 2(D)-4(Pd) profile was high, but it was not statistically significant. 3. The results obtained by multivariate cluster analysis of MMPI T-scores can be divided into 3 subgroups; 1) 9% showed the psychiatric tendency of F-6(Pa)-9(Ma)profile, 2) 44.2% showed no significant profile, 3)46.5% showed the neurotic tendency of 1(Hs)-2(D)-3(Hy)-4(Pd) profile. 4. Since 44.2% showed no significant profile on the MMPI, much more alcoholic patients were caused not by personality factors but by social tolerance, and also by increasing apportunities of drinking in Korean society. 5. When analyzed with Sasang Constituional approach, 1) for the Soyangin (少陽人): 6(Pa) scale was particularly high, 1(Hs) and 3(Hy) scales were low compared to others, 2) for the Taiumin(太陰人): 1(Hs)-2(D)-3(Hy)-4(Pd) neurotic profile was high, the K-scale and 4(Pd)scale were high compared to the Soyangin, 3) for the Soumin(少陰人): 1(Hs)-2(D)-3(Hy)-4(Pd) neurotic profile and 7(Pt) scale were also high.

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Management of Acute Otitis Media and Acute Sinusitis: Clinical Guidelines (급성 중이염 및 급성 부비동염의 치료: 가이드라인을 중심으로)

  • Jo, Dae Sun
    • Pediatric Infection and Vaccine
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    • v.15 no.2
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    • pp.100-107
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    • 2008
  • Acute otitis media and acute sinusitis are some of the most common antibiotic-prescribed diseases in childhood. Usually, with an accurate diagnosis, a 10-14 day course of antibiotics is recommended to cover common causative agents, including pneumococci. Establishment of management guidelines for these infectious diseases based on further study of the epidemiologic profile, antibiotic resistance, and clinical circumstances in Korea is needed.

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The Results of the First Ray Forefoot Osteotomy Using Low Profile Wedge Plate without a Bone Grafting for Pes Planus Correction (제 1열 전족부 절골술을 통한 평발 교정에 있어 골이식 없이 사용한 소형 쐐기형 금속판의 치료 결과)

  • Choi, Jun Young;Shin, Myung Jin;Suh, Jin Soo
    • Journal of Korean Foot and Ankle Society
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    • v.21 no.1
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    • pp.7-11
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    • 2017
  • Purpose: We retrospectively analyzed the radiographic and clinical results after the first ray of forefoot osteotomy using low profile wedge plate without additional cancellous bone grafting for pes planus correction. Materials and Methods: Twenty-four patients were enrolled in this study. Medial cuneiform opening wedge osteotomy was performed in 12 patients (Cotton osteotomy, group C) and first metatarsal base osteotomy was performed in 12 patients (group MT). Results: On average, the wedge size was 5.61 mm (5~6 mm). The mean time to radiographic union was 3.18 and 3.27 months in groups C and MT, respectively. Postoperative talonavicular coverage angle, talo-first metatarsal angle (anteroposterior), talo-first metatarsal angle (lateral), talo-calcaneal angle (lateral), medial cuneiform height, and American orthopaedic foot, as well as ankle society midfoot scale were significantly improved in both groups. Nonunion, delayed union or fixation failure was not presented in our series. Conclusion: We have shown that low profile wedge plate was effective in the case of first ray forefoot osteotomy for pes planus correction without any additional cancellous bone grafting.

Study on Sasang Typology Based on the Type-Specific Characteristics with Type-Specific Pathophysiological Symptom and Temperament (소증과 성정을 이용한 사상체질 특성 연구)

  • Lee, Soo Jin;Chae, Han
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.3
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    • pp.359-364
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    • 2014
  • The purpose of this study was to validate the Sasang Digestive function Inventory (SDFI) and Sasang Personality Questionnaire (SPQ) which measures the pathophysiolgoical symptoms and temperament of each Sasang types. The SDFI, SPQ along with Questionnaire for Sasang Constitution Classification II (QSCCII) were measured with 191 College students. The correlation coefficient was measured with Pearson correlation between SDFI and SPQ. The SDFI and SPQ subscale score of each Sasang constitution groups based on QSCCII were compared using analysis of variance and profile analysis. The SDFI and SPQ total score of So-Eum Sasang type were significantly (p<0.001) different compared to those of Tae-Eum and So-Yang type, respectively. The SDFI and SPQ profile of each Sasang type group was significantly (p<0.001) different each other in profile analysis. There were no significant correlation (r=.126, p>0.05) between SDFI and SPQ total score, however the SDFI-Digestion scale showed significant correlation with SPQ subscales. We found that the SDFI and SPQ can measure the Sasang type-specific pathophysiological symptoms and temperaments, and it would be useful for the clinical application and interdisciplinary research when combined together.

A Case Study of Dysgeusia in a Patient with an Acute Thalamic Infarction Treated with Korean Medicine (급성 시상 경색으로 인한 미각 장애 치험 1례)

  • Lee, Mi-rim;Park, Min-jeong;Kim, Gyeong-muk;Cho, Ki-ho;Moon, Sang-kwan;Kwon, Seung-won;Jung, Woo-sang
    • The Journal of Internal Korean Medicine
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    • v.38 no.2
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    • pp.226-234
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    • 2017
  • The case of a 73-year-old Korean female with dysgeusia due to an acute left thalamic infarction is presented. The patient was treated with the herbal medicine Yanggyuksanhwa-tang, in addition to acupuncture and electronic acupuncture treatment. The filter-paper test and Oral Health Impact Profile-14, (OHIP-14) test were administered to evaluate dysgeusia. Post-treatment, the patient's dysgeusia improved. Korean medicine may be an effective treatment for dysgeusia caused by a thalamic infarction.