• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2733-2737
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• 2014

Objective: Molecular pathology tests are often carried for clinicopathological diagnosis and pathologists have established large collections of formalin-fixed, paraffin-embedded tissue (FFPE) banks. However, extraction of DNA from FFPE is a laborious and challenging for researchers in clinical laboratories. The aim of this study was to compare two widely used DNA extraction methods: using a QIAamp DNA FFPE kit from Qiagen and a Cobas Sample Preparation Kit from Roche, and evaluated the effect of the DNA quality on molecular diagnostics. Methods: DNA from FFPE non-small cell lung carcinoma tissues including biopsy and surgical specimens was extracted with both QIAamp DNA FFPE and Cobas Sample Preparation Kits and EGFR mutations of non-small cell lung carcinomas were detected by real-time quantitative PCR using the extracted DNA. Results and Conclusion: Our results showed that DNA extracted by QIAamp and Cobas methods were both suitable to detect downstream EGFR mutation in surgical specimens. Howover, Cobas method could yield more DNA from biopsy specimens, and gain much better EGFR mutation results.

• Imaging Science in Dentistry
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• 제44권1호
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• pp.85-88
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• 2014

Osteosarcoma is a classical malignant bone-forming neoplasm which usually presents with an aggressive clinical course. The current case is presented with the radiographic feature of widening of the periodontal ligament space of the involved teeth, which is considered to be the earliest radiographic manifestation of osteosarcoma involving the jaw bone. The main aim of this case report was to focus on the importance of early diagnosis of this tumor based on clinical and radiographic examinations, and confirmation by histopathology. Considering the rarity of the disease type and particularly taking into account the fast progression and aggressiveness of this neoplasm, it is clear that the presentation of a clinical case represents a major contribution to better understanding of osteosarcomas involving the jaw bone.

• 대한임상검사과학회지
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• 제46권2호
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• pp.54-58
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• 2014

This study aims to understand some related types (to DiSC behavioral ones) through an analysis about DiSC behavioral types of freshmen at the clinical pathology department in the University. In order to do that, a total of 34 male and female students were surveyed. General characteristics and DiSC behavioral types for the targeted students were analyzed for frequency and percentage. For the frequency, the Chi-square test was performed and the level of significance was set to p<0.05. For the elements to select the university at general characteristics from the result of this study, 21 students were found to have selected the university voluntarily (61.8%). For the information about the clinical pathology department, 14 students were found to be informed through media (41.2%) and 7 students were informed through their parents (20.6%). For the DiSC behavioral types of the students majoring in clinical pathology, 18 students were found to be I type (53.0%), 8 students were C type (23.5%), 5 students were S type (14.7%) and 3 students were D type (8.8%). The relevance between general characteristics and DiSC behavioral type were found to be insignificant. As this study is aimed, there is no significant relevance between general characteristics and DiSC behavioral types, but through an understanding of characteristics of the students majoring in the clinical pathology, helping freshmen who are taking their first steps to adapt themselves to a new environment by diagnosing and understanding their behavioral types, understanding behavioral styles of those four types and guiding them in a positive direction, the method should be considered to raise their satisfaction about the major.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2001년도 추계학술대회 및 정기총회
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• pp.29-29
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• 2001

Well bordered solid enlarged 16.7x9.7x8 cm in the size neoplasma was found in a 7-year-old lioness without any clinical signs of diseases in Chonju city zoo and surgically removed. Simple lobes were separated by pale gray yellowish fibrous tissue. The tumor parenchyma was yellowish with numerous cysts, necrotic foci and hemorrhages. Histologically neoplasma was composed of cell nests different in the size and shape with high mitotic activity. Slow invasive spreading on the border was observed. Formation of the narrow ductular lumina bordered the flattened cells leading to keratinization was seen in some places. It was noted by supplemental clinical investigations, that the tumor did not metastasized to other organs. This tumor is considered to be a sample of a malignant tumor without metastatic spreading and was note described in literature yet.

• 대한임상검사과학회지
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• 제37권1호
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• pp.16-21
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• 2005

To find out the effectiveness of clinical examination for detection of dermatophagoides farinae allergen asthma disease, 50 patients (control group) and 50 healthy persons matched by sex and age to the control group, were tested for allergen asthma. The results of the study follow. The ESR there was significantly different from the comparisons of the patients' normal reference values, 95.3 % in ESR, patient groups allergen asthma and heamatology values with control group. The ESR level of allergen asthma patients, $62.23{\pm}35.09$ mm/hr, was higher than that of the controls, $9.47{\pm}5.36$ mm/hr (p<0.001). The eosinophil count level of the patients, $370.65{\pm}365.45mm^3$, was higher than that of the controls with $171.99{\pm}131.80mm^3$ (p<0.001). The IgE level of the patients, $1137.79{\pm}784.69IU/ml$, was higher than that of the controls with $71.29{\pm}14.28 IU/ml$ (p<0.001).

• 아동학회지
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• 제29권3호
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• pp.1-21
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• 2008

This research explored links between mother/child personality characteristics based on their diagnostic and clinical pathology. The 232 participants, selected from mother-child pairs receiving psychological care in a hospital setting, were tested and interviewed by clinical practitioners. Correlations were found between mothers' Psychopathic Deviate, Paranoia, Psychasthenia, and Schizophrenia and sons' Psychasthenia, aggression, alienation, depression, and anger. Mothers classified with Hysteria were likely to have aggressive children. Mothers with low self-esteem, repression, frustration, and strong levels of extroversion had daughters with anger/rage issues. Sons of mothers diagnosed with Hypochondriasis, Depression, Hysteria, Psychopathic Deviate, Paranoia, and Psychasthenia had high rates of Oppositional Defiant Disorder and ADHD. Children of mothers diagnosed with depression had high rates of ADHD. Specifically, mothers with Hypochondriasis, Hysteria, and Psychopathic Deviate had daughters with high rates of ADHD.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.20-25
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• 2003

Classification of pig diseases in clinical cases ㆍ Digestive system ㆍ Respiratory system ㆍ Reproductive system ㆍ Nervous system ㆍ Others. (omitted)

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.35-38
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• 2003

The parathyroid gland is probably the simplest endocrine organ in the body. The only cells of clinical significance are the parathyroid or chief cells. The primary signal that these cells listen to is calcium. Primary hyperparathyroidism is due to a parathyroid adenoma. The most common cause of hypercalcemia in veterinary medicine is hypercalcemia of malignancy associated with variety of neoplasms. Secondary hyperparathyroidism is due to a disease process, most commonly associated with renal and nutritional hyperparathyroidism. Primary and secondary hyperparathyroidism are markedly different in their clinical, laboratory, and pathogenic mechanism.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2008년도 추계학술대회
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• pp.149-149
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• 2008

• 대한세포병리학회지
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• 제15권1호
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• pp.56-59
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• 2004

Development of an invasive squamous cell carcinoma within a branchial cleft cyst (branchiogenic carcinoma) is very rare and this case is the first description of cytologic findings in Korea. A 62-year-old man presented with a 5-month history of an enlarged right neck mass. Fine needle aspiration cytology of the mass showed low cellularity and the background containing proteinaceous debris, inflammatory cells, and histiocytes suggested a cystic nature. Abundant lymphocytes, a few anucleated squames, and rare atypical squamous cells with pyknotic nuclei and abnormal keratinization were also noted. After excision of the mass, histologic findings were consistent with a branchiogenic carcinoma. We recommend to raise the possibility of carcinoma (primary or metastatic) when we observe a few dyskeratotic cells in a cystic mass within the neck area, especially in an old male.