• Title/Summary/Keyword: Clinical consequences

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Protein Inhibition Precipitation of Calcium Phosphate in Human Saliva (인간 타액내 항 린산칼슘 침전 단백질)

  • Song Han
    • Journal of Oral Medicine and Pain
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    • v.20 no.1
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    • pp.7-18
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    • 1995
  • The Purpose of this article is to describe the biochemical properties and biological functions of several salivary proteins that possess the unusual properties of inhibiting spontaneous and secondary precipitation of calcium phosphate. This function is very important since human salivary secretion is supersaturated with respect to calcium phosphate. Biological function of statherin, proline rich protein (PRP) and histidine rich protein (HRP) is to inhibit precipitation of calcium phosphate in salivary glands, in the oral fluids, and onto tooth surfaces. The resulting supersaturated state of the salivary secretions contributes a protective and reparative environment which is important for the integrity of the tooth. Beneficial consequences of salivary supersaturation with respect to calcium phosphate are selectively expressed in the oral cavity- that is, protection is provided for the dental enamel-while undesirable consequences, for example, precipitation of calcium phosphates in the salivary glands and onto the teeth do not occur. Purification and structural characteristics of these proteins as well as clinical significance of functions of each protein will be discussed.

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Safe clinical photography: best practice guidelines for risk management and mitigation

  • Chandawarkar, Rajiv;Nadkarni, Prakash
    • Archives of Plastic Surgery
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    • v.48 no.3
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    • pp.295-304
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    • 2021
  • Clinical photography is an essential component of patient care in plastic surgery. The use of unsecured smartphone cameras, digital cameras, social media, instant messaging, and commercially available cloud-based storage devices threatens patients' data safety. This paper Identifies potential risks of clinical photography and heightens awareness of safe clinical photography. Specifically, we evaluated existing risk-mitigation strategies globally, comparing them to industry standards in similar settings, and formulated a framework for developing a risk-mitigation plan for avoiding data breaches by identifying the safest methods of picture taking, transfer to storage, retrieval, and use, both within and outside the organization. Since threats evolve constantly, the framework must evolve too. Based on a literature search of both PubMed and the web (via Google) with key phrases and child terms (for PubMed), the risks and consequences of data breaches in individual processes in clinical photography are identified. Current clinical-photography practices are described. Lastly, we evaluate current risk mitigation strategies for clinical photography by examining guidelines from professional organizations, governmental agencies, and non-healthcare industries. Combining lessons learned from the steps above into a comprehensive framework that could contribute to national/international guidelines on safe clinical photography, we provide recommendations for best practice guidelines. It is imperative that best practice guidelines for the simple, safe, and secure capture, transfer, storage, and retrieval of clinical photographs be co-developed through cooperative efforts between providers, hospital administrators, clinical informaticians, IT governance structures, and national professional organizations. This would significantly safeguard patient data security and provide the privacy that patients deserve and expect.

A study on the Development of Traditional Korean Medicine Clinical Practice Guideline for Atopic Dermatitis (아토피피부염의 한의학 진료 지침 개발을 위한 사전 연구)

  • Yun, Young-Hee;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.25 no.2
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    • pp.38-48
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    • 2012
  • Background : The atopic dermatitis patient and their families are looking for safer herb-medicine treatments that possess therapeutic effects, but without the recurrence of symptoms and long-term harmful consequences that can result from other treatment. However, for many reasons, including methodological difficulties and lack of high quality study like randomized clinical study and systematic review, there are no consistent clinical guide line for atopic dermatitis in Traditional Korean Medicine. Objectives : Evidence-based clinical practice guidelines support clinical decision-making by making recommendations to guide clinical practice. The purpose of this study was to develop Traditional Korean Medicine clinical practice guideline for atopic dermatitis Result : The future guide should be based on scientific evidence and include the followings: (1) diagnosis of atopic dermatitis (2) the pattern identification of atopic dermatitis (3) classification of Sasang Constitution (4) efficacy assessment (5) treatment guideline (6) education for patients and care givers Conclusion : The development of Traditional Korean Medicine clinical practice guideline for atopic dermatitis is needed.

Study on a Clinical Collaborative Communication System in Healthcare Organizations -Focused on Patient Education (보건의료 조직의 협업적 의료 커뮤니케이션 시스템에 대한 연구 - 환자교육을 중심으로)

  • Park, Hwagyoo
    • The Journal of Korean Association of Computer Education
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    • v.16 no.2
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    • pp.79-90
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    • 2013
  • Communication errors have severe consequences clinical quality and disputes in medical organizations. Thus, clinical communication has become a major practice recently, since clinical and managerial effectiveness can also be enhanced by improving the quality of the physician, medical staff, and laboratories interactions. Both medium and large-sized hospitals are increasingly adopting the philosophy to shorten clinical service time while enhancing higher medical service quality and lower healthcare service costs. From this motivation, this paper studies on the clinical collaborative communication concept and investigates approaches to the philosophy for implementation. The system has been theorized to improve communication and enhancing medical outcome qualities. In addition, to validate the system, the author analyzes the efficiency and effectiveness in S hospital, using statistical survey works.

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Journey of the Human Papillomavirus (HPV) in a Developing Country over 5 Years (2010 - 2015)

  • Danial, M;Sivasangari, S;Arulappen, AL;Ong, LM
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1363-1368
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    • 2016
  • Human papillomavirus (HPV) is a prevalent sexually transmitted infection with serious medical, sexual, and relationship consequences. HPV vaccine protection is available globally but unfortunately vaccine uptake is inconsistent everywhere. From this study, it was observed that the awareness of cervical cancer, HPV virus and HPV vaccination in Malaysia is high, at 83.1%, 73.9% and 73.3% of respondents, respectively. However, a considerably low percentage had undergone HPV vaccination (8.6%) compared to those who had experienced a Pap smear (32.9%). Awareness between cervical cancer and HPV virus and vaccination was low. Health care providers and the governing bodies have to play a vital role in disseminating holistic information on the vaccine and the importance of getting vaccinated to the public more vigorously in Malaysia.

Effect of HWANGRYUNHAEDOKTANG herd-acupuncture on functional headache (황연해독탕약침(黃連解毒湯藥針)의 기능성두통(機能性頭痛) 치료(治療) 효과(效果)에 대한 임상적(臨床的) 고찰(考察))

  • Choi, Eun-Gyu;Gu, Byung-Su
    • Journal of Oriental Neuropsychiatry
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    • v.11 no.1
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    • pp.75-81
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    • 2000
  • A clinical analysis was carried out for 37 patients who was treated for functional headache with HWANGRYUNHAEDOKTANG(黃連解毒湯) herb-acupuncture in Seoul Red-Cross Oriental Hospital. The results were as follows; 1. The effect of HWANGRYUNHAEDOKTANG(黃連解毒湯) herb-acupuncture for functional headache was turned out to be better effective the young and middle age than the old. 2. Man was better effective than woman 3. There were effective at tention headache and migraine. 4. There were effective within 6 monthes from onset. 5. There were availability in according with increasing treatment. Through the clinical consequences of therapy mentioned above, we came to confirm regular therapeutic effects for functional headache and hereafter, it is considered that a clinical comparative study on oriental cure and herb-acupuncture therapy for headache has to be more progressed than now.

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Drug allergy in children: what should we know?

  • Park, Ji Soo;Suh, Dong In
    • Clinical and Experimental Pediatrics
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    • v.63 no.6
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    • pp.203-210
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    • 2020
  • The drug allergy "label" may have a lifetime of consequences for a child. Many children with alleged drug allergies are proven to be tolerant to the culprit medication when challenged. The field of drug hypersensitivity is a recently evolving field of research, but studies on its epidemiology and diagnostic tools are lacking in children. Clinical history is significant in the diagnosis and classification of drug hypersensitivity in children. Diagnostic tools have been evaluated in a limited number of children; therefore, the guidelines are mainly in line with those for adults. Here, we review the clinical characteristics, main drugs, risk factors, and diagnosis of drug hypersensitivity to aid in its accurate diagnosis in children.

Clinical Application of SPECT and PET in CerebroVascular Disease (뇌혈관질환에서 SPECT와 PET의 임상적 응용)

  • Ra, Young-Shin
    • The Korean Journal of Nuclear Medicine
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    • v.37 no.1
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    • pp.1-12
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    • 2003
  • Single photon emission computed tomography(SPECT) and positron emission tomography(PET) are modern imaging techniques that allow for both qualitative and quantitative assessment of hemodynamic changes in cerebrovascular diseases. SPECT has been becoming an indispensable method to investigate regional cerebral blood flow because equipment and isotope are easily available in most general hospitals. Acetazolamide stress SPECT has also been proved to be useful to evaluate the cerebrovascular reserve of occlusive cerebrovascular diseases and to select surgical candidate. PET has gained wide spread clinical use in the evaluation of the hemodynamic and metabolic consequences of extracranial or intracranial arterial obstructive disease despite its complexity and limited availability. PET has been established as an invaluable tool in the pathophysilogy investigation of acute ischemic stroke. The potentials, limitations, and clinical applications of SPECT and PET in various cerebrovascular diseases will be discussed in this article with reviews of literatures.

Foreign Body Aspiration in Dental Cliniccase -Case Series- (치과에서의 이물흡인 -증례분석-)

  • Park, Won-Seo;Kim, Seong-Tae;Park, Mu-Seok;Seo, Ji-Seon;Kim, Gi-Deok
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.11 no.1
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    • pp.38-44
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    • 2011
  • Despite all preventive efforts, aspiration of foreign body during clinical dental procedures occurs occasionally. Careful clinical physical examination, proper assessment of radiography and prompt emergency treatment can prevent any potentially serious consequences. In this report, we will report serial cases of foreign body in different situation from mild cases to severe cases and suggest some clinical guidelines to dental health care providers.

Mechanism, clinical consequences, and management of dyslipidemia in children with nephrotic syndrome

  • Baek, Hee Sun
    • Childhood Kidney Diseases
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    • v.26 no.1
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    • pp.25-30
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    • 2022
  • Dyslipidemia in nephrotic syndrome (NS) is often characterized by marked increases in the levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, and other lipoproteins, such as very low-density lipoprotein, intermediate-density lipoprotein, and lipoprotein(a). It has been suggested that impaired catabolism of lipoproteins and cholesterol is mainly due to decreased lipoprotein lipase and hepatic lipase activity, and increased biosynthesis of lipoproteins in the liver. The management strategies for dyslipidemia in patients with NS consist of lifestyle modification, lipid-lowering agents represented by statins, second-line agents such as fibrates and bile acid sequestrants, and lipid apheresis. Compared with dyslipidemia in adult NS patients, whose risks of atherosclerotic disease and progressive renal injury are considered high, clinical data on dyslipidemia in pediatric NS patients are limited. Therefore, it is necessary to pay more attention to the evaluation and management of dyslipidemia in pediatric patients with NS in clinical practice.