• 제목/요약/키워드: Clinical characteristic

검색결과 1,042건 처리시간 0.029초

A Classification of lschemic Heart Disease using Neural Network in Magnetocardiogram (심자도에서 신경회로망을 이용한 허혈성 심장질환 분류)

  • Eum, Sang-hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • 제20권11호
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    • pp.2137-2142
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    • 2016
  • The electrical current generated by heart creates not only electric potential but also a magnetic field. In this study, the signals obtained magnetocardiogram(MCG) using 61 channel superconducting quantum interference device(SQUID) system, and the clinical significance of various feature parameters has been developed MCG. Neural network algorithm was used to perform the classification of ischemic heart disease. The MCG signal was obtained to facilitate the extraction of parameters through a process of pre-processing. The data used to research the normal group 10 and ischemic heart disease group 10 with visible signs of stable angina patients. The available clinical indicators were extracted by characteristic point, characteristic interval parameter, and amplitude ratio parameter. The extracted parameters are determined to analysis the significance and clinical parameters were defined. It is possible to classify ischemic heart disease using the MCG feature parameters as a neural network input.

Evaluation of Clinical Usefulness of Gamma Glutamyl Transferase as a Surrogate Marker for Metabolic Syndrome in Non Obese Adult Men (비만하지 않은 성인 남성에서 대사증후군의 대리 표지자로서 감마 글루타밀 전이효소의 임상적 유용성 평가)

  • Shin, Kyung-A;Kim, Eun Jae
    • Journal of Convergence for Information Technology
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    • 제10권12호
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    • pp.146-155
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    • 2020
  • This study was to evaluate the usefulness of gamma glutamyl transferase (GGT) as a surrogate marker predicting metabolic syndrome. 7,155 non obese men over the age of 20 were studied as subjects. The criteria for diagnosing MetS were the National Cholesterol Education Program - Third Adult Treatment Panel (NCEP-ATP III). The risk of developing MetS according to GGT was conducted logistic regression analysis, and the ROC (receiver operating characteristic) curve was obtained to confirm GGT ability to predict the risk of MetS. Regardless of age and body mass index, MetS had a 7.09 times higher risk of onset in the fourth quartile than in the first quartile of GGT (p<0.001). The AUC (area under the curve) of GGT for the diagnosis of MetS was 0.715, and the cutoff value of GGT was 40.0 U/L, the sensitivity was 65.0%, and the specificity was 70.2%. Therefore, GGT is considered to be a useful diagnostic index for diagnosing MetS.

Clinical Utility of Haptoglobin in Combination with CEA, NSE and CYFRA21-1 for Diagnosis of Lung Cancer

  • Wang, Bing;He, Yu-Jie;Tian, Ying-Xing;Yang, Rui-Ning;Zhu, Yue-Rong;Qiu, Hong
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권22호
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    • pp.9611-9614
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    • 2014
  • Purpose: To investigate the clinical value in lung cancer of a combination of four serum tumor markers, haptoglobin (Hp), carcinoembryonic antigen (CEA), neuron specific enolase (NSE) as well as the cytokeratin 19 fragment (CYFRA21-1). Materials and Methods: Serum Hp (with immune-turbidimetric method), CEA, NSE, CYFRA21-1 (with chemiluminescence method) level were assessed in 193 patients with lung cancer, 87 patients with benign lung disease and 150 healthy controls. Differences of expression were compared among groups, and joint effects of these tumor markers for the diagnosis of lung cancer were analyzed. Results: Serum tumor marker levels in patients with lung cancer were obviously higher than those with benign lung disease and normal controls (p<0.01). The sensitivities of Hp, CEA, NSE and CYFRA21-1 were 43.5%, 40.9%, 23.3% and 41.5%, with specificities of 90.7%, 99.2%, 97.9% and 97.9%. Four tumor markers combined together could produce a positive detection rate of 85.0%, significantly higher than that of any single test. With squamous carcinomas, the positive detection rates with Hp and CYFRA21-1 were higher than that of other markers. In the adenocarcinoma case, the positive detection rate of CEA was higher than that of other markers. For small cell carcinomas, the positive detection rate of NSE was highest. The area under receiver operating characteristic curve ($AUC^{ROC}$) of Hp in squamous carcinoma (0.805) was higher than in adenocarcinoma (0.664) and small cell carcinoma (0.665). Conclusions: Hp can be used as a new serum tumor marker for lung cancer. Combination detection of Hp, CEA, NSE and CYFRA21-1 could significantly improve the sensitivity and specificity in diagnosis of lung cancer, and could be useful for pathological typing.

An Empirical Study on Stress Experienced by Physical therapist Students during Clinical Training (임상실습시 물리치료과 학생이 경험하는 스트레스에 관한 연구)

  • Park, Seoung-Ha;Jeong, Han-Shin
    • Journal of Korean Physical Therapy Science
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    • 제10권1호
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    • pp.58-64
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    • 2003
  • The study was done in order to better understand the stress which physical therapist experience during clinical training. Clinical training was not confined to understanding training facts and concepts of physical therapist. The data were collected from November 1 to December 15, 2002 and 129 valid questionnaires were obtained and analyzed. They were analyzed by the percent, frequency, t-test, one-way ANOVA and Pearson Correlation Coefficient. The results of the study were as follows: 1. There were in satisfaction degree of major 42.6% of the subjects was revealed as "satisfied" and in satisfaction degree of clinical training 24.0% of the subjects was revealed as "satisfied". 2. There were much stress in relation of physical therapist was revealed as the most severe stress at a mean 15.98 and environment was revealed as severe stress at a mean 12.94. in role was revealed as the lessor stress at a mean 4.12. 3. The state anxiety degree which physical therapist students experience during clinical training was revealed as "moderate" anxiety. 4. There were significant difference between relation of physical therapist and satisfaction degree of clinical training (p<0.05), between ideal and values of physical therapist and health condition(p<0.05), between relation of tint and satisfaction degree of major(p<0.05), between education the characteristic which it will pull out and satisfaction degree of major(p<0.05), satisfaction degree of clinical training(p<0.05).

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Dynamic Chest X-Ray Using a Flat-Panel Detector System: Technique and Applications

  • Akinori Hata;Yoshitake Yamada;Rie Tanaka;Mizuki Nishino;Tomoyuki Hida;Takuya Hino;Masako Ueyama;Masahiro Yanagawa;Takeshi Kamitani;Atsuko Kurosaki;Shigeru Sanada;Masahiro Jinzaki;Kousei Ishigami;Noriyuki Tomiyama;Hiroshi Honda;Shoji Kudoh;Hiroto Hatabu
    • Korean Journal of Radiology
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    • 제22권4호
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    • pp.634-651
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    • 2021
  • Dynamic X-ray (DXR) is a functional imaging technique that uses sequential images obtained by a flat-panel detector (FPD). This article aims to describe the mechanism of DXR and the analysis methods used as well as review the clinical evidence for its use. DXR analyzes dynamic changes on the basis of X-ray translucency and can be used for analysis of diaphragmatic kinetics, ventilation, and lung perfusion. It offers many advantages such as a high temporal resolution and flexibility in body positioning. Many clinical studies have reported the feasibility of DXR and its characteristic findings in pulmonary diseases. DXR may serve as an alternative to pulmonary function tests in patients requiring contact inhibition, including patients with suspected or confirmed coronavirus disease 2019 or other infectious diseases. Thus, DXR has a great potential to play an important role in the clinical setting. Further investigations are needed to utilize DXR more effectively and to establish it as a valuable diagnostic tool.

Comparison of Clinical Characteristics between Occupational and Sporadic Young-Onset Cholangiocarcinoma

  • Kaneko, Rena;Kubo, Shoji;Sato, Yuzuru
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권16호
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    • pp.7195-7200
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    • 2015
  • Background: Since seventeen employees of an offset printing company in Osaka, Japan developed cholangiocarcinoma it has become recognized as an occupational cancer. This study investigated the differences of clinical features between occupational cholangiocarcinoma and sporadic young-onset cholangiocarcinoma. Materials and Methods: Thirty-four young adults (<50 years old) with sporadic cholangiocarcinoma were extracted from the Rosai Hospital Group database (sporadic group) and their clinical features were compared with those of 17 patients with occupational cholangiocarcinoma (occupational group). Results: The 34 patients in the sporadic group were treated for cholangiocarcinoma at 16 different Rosai hospitals. There were significant differences of age (p<0.01), gender (p<0.01), abnormal laboratory tests (p<0.01), and tumor location (p<0.01) between the two groups. The percentage of patients with abnormal laboratory tests was significantly higher in the occupational group than in the sporadic group (p<0.001). Regional dilation of bile ducts, which is a characteristic of occupational cholangiocarcinoma, was not observed in the sporadic group. Conclusions: No cluster of cholangiocarcinoma cases was identified in the Rosai Hospital database. There were differences of clinical features between occupational and sporadic cholangiocarcinoma, which might be helpful for diagnosing occupational cholangiocarcinoma in the future.

Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence

  • Jalali, Elnaz;Ferneini, Elie M.;Rengasamy, Kandasamy;Tadinada, Aditya
    • Imaging Science in Dentistry
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    • 제47권2호
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    • pp.135-140
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    • 2017
  • Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC.

Cytology of the Uterine Cervico-vaginal Smear of Clear Cell Adenocarcinoma in Uterine Cervix - Report of a Case - (자궁경부 투명세포 샘암종의 자궁경부질 세포학적 소견 - 1예 보고 -)

  • Maeng, Lee-So;Kim, Kyouug-Mee;Kang, Chang-Suk;Lee, An-Hi
    • The Korean Journal of Cytopathology
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    • 제15권2호
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    • pp.116-119
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    • 2004
  • Primary clear cell adenocarcinoma of uterine cervix is rare and cytomorphology in the vaginal smear have not been previously described in Korean literatures. The cytologic characteristics of clear cell adenocarcinoma of the uterine cervix include : malignant cells with abundant, finely vacuolated cytoplasm ; hobnail appearance, and distinctive basement membrane-like hyaline materials within cellular aggregates. A 36-year-old woman presented with vaginal bleeding. Cytologic examination of vaginal smear and histopathologic examination of a radical hysterectomy specimen allowed the diagnosis of hemorrhagic tumor in the uterine cervix as a clear cell adenocarcinoma. Cytologic findings were very characteristic. The tumor cells had abundant, pale, finely vacuolated cytoplasm with indistinct cytoplasmic membrane. The nuclei were round to oval with finely dispersed chromatin. Extracellular basement membrane-like hyaline substance, which stained a light green color in Papanicolaou's preparation, was frequently observed within the cancer cell clusters.

The Influence of Job Characteristics and Professionalism on Empowerment Perceived by Nurses (임상 간호사의 직무특성과 전문직업성이 임파워먼트에 미치는 영향)

  • Lee, So-Young
    • Journal of Korean Academy of Nursing Administration
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    • 제12권4호
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    • pp.587-596
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    • 2006
  • Purpose: This study aimed to understand the empowerment in clinical nurses and to analyze the influences of job characteristics and professionalism on empowerment. Method: Subjects were 386 nurses in 8 general hospitals at G city and Seoul. Data were collected with self-administered questionnaires and analyzed using SAS 8.1 by applying ttest, ANOVA, Pearson correlation coefficient, and Stepwise multiple regression. Results: Empowerment was $3.58{\pm}0.63$ and among the subscale scores meaningfulness $(3.83{\pm}0.74)$ was the highest and Impact $(3.23{\pm}0.86)$ was the lowest. The level of empowerment was different significantly by age, marital state, education, clinical careers, position, job satisfaction(p<.00). Job characteristic score was $3.60{\pm}0.45$ and Professionalism score was $3.65{\pm}0.52$. Empowerment was positively correlated with job characteristics and professionalism(r= .63, .81, p<.01). Major factors that affect to empowerment in clinical nurses was professionalism, which had an explanation of 66.9%. Conclusions: The more clinical nurses took the professionalism, the higher nurses perceived empowerment. Therefore, empowerment and professionalism in nurses should be generally screened and other factors should be looked into. And if the specified nursing intervention program which increase their empowerment would be developed, it may contribute to qualify the nursing services.

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Comparative Analyses of the Clinical Characteristic and Medical Cost against Surgical Procedures for Intertrochanteric Fracture in the Elderly Patients (노인의 대퇴전자간 골절의 수술적 방법에 따른 임상적 특성 및 의료비용 비교)

  • Choi, Mi-Na
    • Journal of Korean Academy of Nursing Administration
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    • 제13권2호
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    • pp.199-207
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    • 2007
  • Purpose: Clinical characteristics and medical cost were analyzed according to the surgical procedures for intertrochanteric fracture in aged patients to assess the appropriateness of treatment expense and to find possibility of reducing the medical cost. Method: Variable for the statistical analysis were; the clinical characteristics, medical cost according to the surgical procedures, the treatment success rate, the total medical expense, and the average expense per case. SAS Package Version 8.02. was used to analyze the relevant data. Results: Operative procedures differ significantly according to the gender and by the location of institution. Only significant clinical variables according to the operative procedure were duration of general anesthesia and amount of blood transfusion. Average cost per treatment was the highest in the bipolar hemiarthroplasty followed by the gamma nail and hip compressing screw. Average cost for bipolar hemiarthroplasty was significantly higher than other surgical procedures. Conclusions: The difference in hospital costs for treatment of intertrochanteric fracture originates from the utilized surgical procedures, mostly by the materials used. The method of surgical treatment should be carefully determined by the purpose of the surgery, in order to improve the quality of medical care and also to reduce the hospital cost.

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