• Anxiety and mood
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• v.3 no.1
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• pp.8-14
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• 2007

Although treatments of anxiety symptom have been available for decades, the biological basis for anxiety disorders in humans is just beginning to emerge. Recently, there is a growing body of literature suggesting that group II metabotrpic glutamate (mGlu) receptors and group I mGlu receptors are important in the physiological and behavioral sequelae associated with stressful stimuli. Moreover, compounds selective for mGlu receptors, particularly mGlu2/3 and/or mGlu5, have proven as effective as classical anxiolytics in various animal models of anxiety without producing many of the unwanted side effects that are typical of current therapies. This article will focus on the emerging preclinical and clinical data that implicate modulation of the mGlu receptors as a potential anxiolytic strategy.

• Journal of the Korea Convergence Society
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• v.9 no.3
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• pp.79-90
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• 2018

The purpose of this study was to investigate the difference of individuals with social anxiety tendency and normal people according to existence of emotional context in attention processing for positive facial stimulation. To do this, we investigated attentional processing for positive face stimuli in a condition without/with emotional context. SADS and CES-D were administered to 800 undergraduate students in D city and the social anxiety group (SA, n=24) and the normal control group (NC, n=24) were selected. In order to measure the two factors of attention process (attention engagement and attention disengagement), first gaze direction and first gaze time were measured through eye-movement tracking. The results show that the SA group exhibited faster attention disengagement from positive face stimuli compared to the NC group in the condition without context. But, when the positive context presented with positive face stimuli, there is no difference between SA and NC. This result suggests that the positive background affects emotional processing of social anxiety disorder.

• Journal of Korean Critical Care Nursing
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• v.14 no.1
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• pp.1-13
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• 2021

Purpose : Based on Quint's theory and the relevant literature, this study constructed a structural equation model for explaining and predicting end-of-life care performance in clinical nurses. Methods : A self-administered questionnaire was used to collect data from 265 nurses between September 1 and September 30, 2016. The data were analyzed using SPSS ver. 21 and AMOS ver. 21. Results : The goodness of fit of the modified model was found to be relatively satisfactory (χ2=114.82, Nomed χ2(χ2/df)=2.44, SRMR=.06, GFI=.94, AGFI=.89, CFI=.95, TLI=.91, RMSEA=.07). End-of-life care performance was affected by the attitudes toward nursing care of the dying, working unit, and death anxiety. The attitudes toward such care had the highest effect on end-of-life care performance. Conclusion : The results suggest that end-of-life care performance is directly and indirectly affected by attitudes toward nursing care of the dying, participation in end-of-life care education, working unit, death perception, and death anxiety. To improve clinical nurses' end-of-life care performance, effective programs to promote death anxiety and attitudes toward nursing care of the dying need to be developed. In addition, hospital nursing organizations should attempt to produce concrete measures for death anxiety and terminal care attitudes in clinical nurses.

• Journal of Oriental Neuropsychiatry
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• v.34 no.4
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• pp.403-420
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• 2023

Objectives: This study investigated the effectiveness of herbal medicine for generalized anxiety disorder (GAD) based on recent clinical studies. Methods: Studies were searched through four databases. Clinical research studies on herbal medicine treatment for GAD patients were included. The studies were analyzed according to study design, diagnostic criteria, population, and intervention. A risk of bias assessment was performed to assess the quality of the included randomized controlled trials (RCT). If the intervention applied to the treatment and control groups was the same and two or more studies were reporting the same items as outcome indicators, a meta-analysis was performed. Results: A total of 19 studies, including 12 RCTs were selected. The most common pattern identification was 'Phlegm fire disturbing upward' (痰熱上擾), and the most used herb for therapeutic purposes was 'Rhizome of Poria cocos' (茯苓). Meta-analysis results of three studies showed that there were no significant differences in effectiveness between the herbal medicine intervention and the Western medicine intervention. Meta-analysis results of five studies showed that the Hamilton Anxiety Rating Scale was significantly reduced in the case of herbal medicine intervention compared to Western medicine intervention. Conclusions: The results of our study demonstrated that herbal medicine treatment for GAD is effective in alleviating anxiety symptoms and chief symptoms of GAD. However, this study has several limitations; there was a lack of placebo-controlled RCT and an absence of objective diagnostic criteria in case reports. Therefore, further well-designed clinical studies, conducted based on the results of this study, are recommended.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.6
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• pp.1533-1537
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• 2003

This double-blind randomized clinical trial was performed to evaluate the anti-anxiety, anti-stress effect of a modified formula WS-01 consisted with several herbs(Jujubae Fructus. Longanae Arillus. Poria Cocos) and germinated rice. The extract of the formula was administered (p.o) to 24 students and placebo was to 23 students for 4 weeks. STAI-KYZ(Hahn. Hakjisa), ABR2000(Meridian, Korea), CBC, LFT, U/A were checked before and after the administration period. There was no difference between the STAI score of WS-01 and that of placebo group in first test. But the STAI state anxiety score was 5.33±7.33 reduced in WS-01 group and it was 0.52±6.42 increased in placebo group in second test. this result was significant stastically. 10 students in WS-01 group showed improving result, but only 1 student in placebo group showed improving result of ABR2000 test. The result of ABR2000 was analyzed with curve 2, Regulation 2, and graph 1,2,3, because those reflect central nerve system and stressful condition of the body. There was no significant result in first and second CBC, LFT, Urine test. The results of this clinical study suggest that WS-01 has anti-anxiety, anti-stress effect, and it could be applied to various conditions or disorders related with anxiety and stress.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.4
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• pp.345-355
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• 2021

Background: This study aimed to evaluate the efficacy of external vibrating devices and counterstimulation on a child's dental anxiety, apprehension, and pain perception during local anesthetic administration. Methods: This was a prospective, randomized, parallel-arm, single-blinded interventional, clinical trial. One hundred children aged 4-11 years, requiring pulp therapy or extraction under local anesthesia (LA), were recruited and allocated equally into two groups (1:1) based on the interventions used: Group BD (n = 50) received vibration using a Buzzy^® device {MMJ Labs, Atlanta, GE, USA} as a behavior guidance technique; Group CS (n = 50) received counterstimulation for the same technique. Anxiety levels [Venham's Clinical Anxiety Rating Scale (VCARS), Venham Picture Test (VPT), Pulse oximeter {Gibson, Fingertip Pulse Oximeter}, Beijing, China)] were assessed before, during, and after LA administration, while pain perception [Wong-Baker Faces Pain Rating Scale (WBFPS), Visual Analogue Scale (VAS)] was evaluated immediately after injection. Statistical analysis was performed using the Student's t-test to assess the mean difference between the two groups and the repeated measures ANOVA for testing the mean difference in the pulse rates. Statistical significance was set at P < 0.05. Results: Significant differences in mean pulse rate values were observed in both groups. In contrast, the children in the BD group had higher diminution (P < 0.05), whereas the mean VCARS and VPT scores were conspicuous (P < 0.05). Based on the mean WBFPS and VAS scores, delayed pain perception after LA injection was more prominent in the BD group than in the CS group. Conclusion: External vibration using a Buzzy^® device is comparatively better than counterstimulation in alleviating needle-associated anxiety in children requiring extraction and pulpectomy.

• Journal of Oriental Neuropsychiatry
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• v.33 no.1
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• pp.33-48
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• 2022

Objectives: Academic stress poses a significant risk for the mental health of medical students, and a feasible group intervention program for managing academic stress is required. The purpose of this study was to examine the clinical effectiveness of emotional freedom techniques (EFT) on the mental health of Korean medical students. Methods: The class of first-year medical school students (n=36) participated in an after-school EFT group intervention program comprising six sessions (15 minutes/session, three weeks) to analyze its clinical effectiveness as a single-group test-retest clinical study. The changes in the Perceived Stress Scale (PSS), Test Anxiety Inventory (TAI), Positive and Negative Affect Schedule (PANAS), and State-Trait Anxiety Inventory (STAI) scores were examined using a paired t-test and Cohen's D at post-EFT and two-week follow-up. Results: There were significant curtailments at post-EFT and follow-up measures in TAI-Total (t=2.704 and t=3.289), TAI-Worry (t=2.297 and t=2.454), TAI-Emotionality (t=2.763 and t=3.654), PSS-Negative Perspective (t=2.659 and t=3.877), and PANAS-Negative Affect (t=2.885 and t=3.259) subscales, however not in PSS-Positive Perspective (t=-1.279 and t=-1.101) and PANAS-Positive Affect (t=0.194 and t=-0.122) subscales. The trait anxiety (t=2.227) was significantly mitigated in the post-EFT measure and the state anxiety (t=2.30) in the follow-up measure. Conclusions: The EFT group intervention alleviated test stress, negative affect, and anxiety in the Korean medical students. This study contributes to an understanding of academic stress and EFT intervention in the competitive environment of medical education.

• Journal of Industrial Convergence
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• v.22 no.3
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• pp.79-89
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• 2024

This study is a one-group pre-post experimental design that investigates the effects of a practice-based learning program with multiple components on the clinical competence of nursing students, and clinical decision-making. From May 4 to 29, 2020, a total of 60 third-year nursing students with no clinical practice experience were divided into two teams and participated in multi-component practice-based education for two weeks each, and the data of the final 51 students were included in the analysis. Following the practicum, there was a significant increase in clinical competence (t=-4.74, p<.001) and self-confidence in clinical decision-making (t=-8.41, p<.001), and a decrease in anxiety related to clinical decision-making (t=2.54, p=.014). The findings suggest that a multi-component, practice-based learning approach for nursing students can enhance their clinical competence, reduce preclincal anxiety and increase confidence in clinical decision-making in patient care.

• Journal of Oriental Neuropsychiatry
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• v.18 no.3
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• pp.157-164
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• 2007

The SRP program(stress reduction program) is reported has a good effect to patient to escape from anxiety. To reduce several symptoms due to anxiety, we performed some SRP programs to our patient who had suffered anxiety disorder. The measurement tools of patient's improvement we used are Heart Rate Variability and State-Trait Anxiety Inventory. Through this programs, symptoms and feeling of anxiety were decreased than first time and Autonomic nerve system balance was much improved. this is caused by effort of self-control meditation, mindfullness, breathing instruction and muscle relaxation program.

• International Journal of Advanced Culture Technology
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• v.9 no.4
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• pp.254-259
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• 2021

Time management skills are essential for Occupation Therapy students' success, and development of clinical competence. The purpose of this study was to determine the relationship between time management skills and anxiety and academic motivation of nursing students. This study was carried out on 95 Occupation Therapy students. Data were collected using demographic Questionnaire, Time Management Questionnaire (TMQ), Spielberger State-Trait Anxiety Inventory (STAI) and Academic Motivation Scale (AMS), which was completed t by self-report. Data were analyzed using SPSS 20 software with descriptive and analytical statistics such as ANOVA, independent t-test, Regression and Pearson Correlation Coefficient. The results also showed a statistically significant negative correlation between the students' TMQ scores and the state anxiety (r= -0.282, p< 0.005) and trait anxiety scores (r= -0.325, p<0.005). Moreover, there was a statistically significant positive correlation between the students' TMQ scores and AMS scores (r= 0.279, p< 0.005). Regarding the findings, it seems that it is necessary to plan for improving time management skills in order to enhance academic motivation and reduce anxiety rates among Occupation Therapy students.