• Title/Summary/Keyword: Clinical Practice Stress

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Effects of Regional Hyperthermia with Moderate Temperature on Cancer Treatment (국부 중등도 온열요법의 암치료 효과)

  • Kang, Chi-Dug;Kim, Sun-Hee
    • Journal of Life Science
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    • v.26 no.9
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    • pp.1088-1096
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    • 2016
  • Despite that moderate hyperthermia can exert various antitumor activities such as direct cytotoxic effects on tumor cells, effects on tumor vasculatures and immunological effects, hyperthermia has been usually combined with radiotherapy or chemotherapy due to its limited efficacy in cancer treatment, showing some positive clinical benefits with generally well-tolerated side effects. Since heat shock responses itself can interfere with the anti-tumor effects of hyperthermia, not all of these studies might have demonstrated positive clinical outcomes in cancer patients. Therefore, the negative anti-tumor effect of hyperthermia should be reduced to enhance the effectiveness of hyperthermia. Although the responses to heat stress of tumor tissues containing vessels, immune cells, connective tissues as well as cancer cells, are very complicated, it is needed to study in the near future if some clinically available drugs, which can modulate heat stress responses, can improve the efficacy of hyperthermia in patients with cancer. In this review, the effect of clinical hyperthermia centered on non-invasive external hyperthermia using radiofrequency at moderate temperature will be discussed, since it is the state-of-the-art technology in the current clinical practice of hyperthermia, and a moderate operational temperature is used to increase the therapeutic effectiveness of conventional therapy without additional toxicity to normal tissues.

The effects of the DASH diet education program with omega-3 fatty acid supplementation on metabolic syndrome parameters in elderly women with abdominal obesity

  • Choi, Seung-Hye;Choi-Kwon, Smi
    • Nutrition Research and Practice
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    • v.9 no.2
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    • pp.150-157
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    • 2015
  • BACKGROUND/OBJECTIVES: The purpose of this study was to investigate the overall effects of a tailored Dietary Approaches to Stop Hypertension (DASH) nutritional intervention program which included omega-3 fatty acids supplementation, on dietary self-efficacy, dietary knowledge, and dietary behaviors in Korean elderly women with abdominal obesity. Furthermore, we investigated the effects of the program on metabolic syndrome parameters including the antioxidant capacities in these subjects. SUBJECTS/METHODS: A randomized, controlled trial was conducted for 8 weeks. The experimental group (n = 21) received a weekly tailored nutritional program for 8 weeks and the control group (n = 18) received only one educational session. The clinical survey was conducted before and after the intervention period. RESULTS: After the intervention, dietary self-efficacy (P = 0.023), frequency of fruit intake (P = 0.019), and dietary fiber intake (P = 0.044) were higher in the experimental group than in the control group. The oxidative stress (P < 0.001) was lower in the experimental group than in the control group. Moreover, low density lipoprotein (LDL) cholesterol (P = 0.023) had significantly decreased in the experimental group but not in the control group after the intervention. CONCLUSIONS: The intervention program including omega-3 fatty acid supplementation had a positive effect on dietary self-efficacy, dietary behaviors, and oxidative stress among aged women with abdominal obesity.

Influence of Religious Beliefs on the Health of Cancer Patients

  • Tsai, Tai-Jung;Chung, Ue-Lin;Chang, Chee-Jen;Wang, Hsiu-Ho
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2315-2320
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    • 2016
  • Background: This study investigated the influence of religious beliefs on the health of cancer patients and identified the factors contributing to the influence. Materials and Methods: A questionnaire survey was conducted using a convenient sampling method. A structured questionnaire was used to the samplings, and the data of 200 cancer patients were collected. Results: The effects of religion on the health of cancer patients achieved an average score of 3.58. The top five effects are presented as follows: (a) Religion provides me with mental support and strength, (b) religion enables me to gain confidence in health recovery, (c) religion motivates me to cope with disease-related stress positively and optimistically, (d) religion helps me reduce anxiety, and (e) religion gives me courage to face uncertainties regarding disease progression. Moreover, among the demographic variables, gender, type of religion, and experience of religious miracles contributed to the significantly different effects of religion on patients. Specifically, the effect of religion on the health of patients who were female and Christian and had miracle experiences was significantly (p< .01) higher than that on other patients. Conclusions: These results are helpful in understanding the influence of religious beliefs on the health of cancer patients and identified the factors contributing to the influence. The result can serve as a reference for nursing education and clinical nursing practice.

How can We Make Satisfiable Dental Restorations? (모두에게 만족을 주는 보철물은 어떻게 만들어지는가?)

  • Ahn, Seung-Geun
    • Journal of Dental Rehabilitation and Applied Science
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    • v.21 no.2
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    • pp.183-189
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    • 2005
  • There is no single or simple answer for effective communication between laboratory technician and clinical dentist. Love-hate could be used to describe the relationship between dentists and their labs. Great lab work can make a dentists life much easier and can result in getting many referrals. However, if the lab work is not up to par and/or late, it can add stress and agony to a dentists practice. Also the opposition is right. If the preparations are calibrated, the impressions clear, and the bite registrations accurate, most labs can do their work reasonably well. Unfortunately, many cases received by labs are barely adequate, especially when it comes to reading margins, which are frequently created by the imagination of the person trimming the dies. In other words, both dentists and lab technicians need to be able to understand how each party operates so that solutions to problems can be found. Effective communication with the laboratory is critical if any degree of success is desired.

Change of Paradigms in Caries-Associated Bacteria in the Caries Process: Ecological Perspectives (치아우식증 유발 균주에 대한 패러다임의 변화: 생태학적 관점)

  • Kim, Hee-Eun
    • Journal of dental hygiene science
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    • v.14 no.2
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    • pp.87-93
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    • 2014
  • Dental plaque resides passively at a site and makes an active contribution to the maintenance of health. The bacterial composition of plaque remains relatively stable despite regular exposure to minor environmental stress. This stability, homeostasis is due to a dynamic balance of microbial interactions. However, the homeostasis can break down, leading to shifts in the balance of the microflora. This change can be a sign of initial dental caries. It is proposed that disease can be prevented or treated not only by targeting the putative pathogens but also by interfering with the processes that drive the breakdown in homeostasis. It is essential to understand the plaque as a mixed species biofilm. In this essay I reviewed an extension of the caries ecological hypothesis to explain the relation between dynamic changes in the phenotypic/genotypic properties of plaque bacteria and the demineralization and remineralization balance of the dental caries process. We will have the strategies to impact significantly on clinical practice as understanding dental biofilm.

Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage

  • Jung, Joohee;Choi, Jae Sue;Jeong, Choon-Sik
    • Toxicological Research
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    • v.30 no.1
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    • pp.45-48
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    • 2014
  • Helicobacter pylori (H. pylori) is the most important factor of gastric disease in clinical practice. Moreover, smoking, stress and a poor diet may be additive factors for gastric damage. With these factors, increasing infection of H. pylori triggers gastritis, gastric ulcers and gastric cancer. To develop a new protective agent, we are concerned with plant-derived extract. The extract of Coptis chinensis (C. chinensis) and its constituents were investigated to assess their protective activities against gastric damage. The C. chinensis extract showed a scavenging effect against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radicals, inhibition of H. pylori colonization and antiulcerogenic activities in rat. In particular, palmatine derived from C. chinensis was found to be the novel protective agent. It is better than the C. chinensis extract, berberine, a well-known constituent of C. chinensis. We suggest that palmatine from the root cortex of C. chinensis may be a good candidate for the development of new pharmaceuticals to prevent gastric disease.

The Convergence Study of Stress Coping and Satisfaction with Clinical Practice to the Grade of Nursing Student's (간호대학생의 학년별 임상실습 스트레스 대처와 실습 만족도에 관한 융합 연구)

  • Park, In-Sook
    • Proceedings of the Korea Contents Association Conference
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    • 2019.05a
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    • pp.419-420
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    • 2019
  • 본 연구는 학년별 임상실습 스트레스 대처와 실습 만족도를 규명하는 조사연구이다. 연구대상자는 K도 J시에 소재한 임상실습 경험이 있는 간호대학생 3학년은 141명, 4학년 142명 총 283명이다. 자료 분석은 SPSS 18.0 WIN 프로그램을 사용하였고, 대상자의 스트레스 대처 중 소극적인 대처 유형은 총 96점에서 3학년 63.75(${\pm}6.57$)점으로 4학년 62.21(${\pm}6.45$)점 보다 높게 나타났으며, 학년간 차이는 통계적으로 유의미하게 나타났다(t= 1.75, p=.045). 대상자의 실습 만족도는 학년간 차이는 실습시간에 대한 만족도가 통계적으로 유의미하게 나타났다(t=2.87, p=.003). 대상자의 스트레스 대처와 실습만족도와의 관계에서는 적극적 대처 유형과 실습내용 만족도(r=.151, p<.05), 소극적 대처 유형과 실습시간 만족도(r=.138, p<.035)는 양의 상관관계를 나타났다. 종합해보면 추후 실습 스트레스에 대한 대처방법으로 임상 실습 전 긍정적이고 목표지향적인 형태를 유지할 수 있는 자극적이고 효율적인 교과과정과 비교과과정에서의 융합 연구가 필요하다고 사료된다.

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A Clinical Study on the Factors Related with the Sequelae of Facial Palsy

  • Kim, Seung-Hyeon;Bae, Jae-Ik;Kim, Jang-Hyun
    • The Journal of Korean Medicine
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    • v.27 no.4
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    • pp.215-224
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    • 2006
  • Objectives : In order to apply useful data to clinical practice, we undertook this study and tried to find factors related with sequelae of facial palsy in relation with patients' age and gender distribution, past history with the disease, condition before onset, duration of recovery time, existence of remaining sequelae, types of the sequelae, and duration for sequelae to disappear. Methods : We evaluated patients' condition (fatigue, stress, chills, cold and so on), past history (diabetes mellitus, hypertension, stroke, herpes zoster, cancer and so on), duration of recovery time, types of the sequelae, age and sequelae distribution as to when the treatments were started as we examined 473 patients who were diagnosed with facial palsy, and visited the Out-patient Department of Acupuncture and Moxibustion of Bundang Oriental Medicine Hospital of Dongguk University through 2003 and 2004. Results : The sequelae of facial palsy were not significantly relevant to the signs found before facial palsy occurred(fatigue, stress, chills, and cold), or to patients' past history (hypertension, diabetes mellitus, facial palsy, herpes zoster). The duration of recovery time was within 30 days for 45.3% of the patients examined in this study, and within 90 days for 72.6%. Evaluating the existence of sequelae in relation to age, we found more in the group comprised of patients aged 50 and over than under 50. We found more sequelae in the group which is consisted of patients who had not been treated until 6 days after than within 5 days from the onset. Conclusion: Attention to sequelae will be needed for patients aged 50 and over and who were not treated until 6 days after the onset, as they had more sequelae.

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Early dropout predictive factors in obesity treatment

  • Michelini, Ilaria;Falchi, Anna Giulia;Muggia, Chiara;Grecchi, Ilaria;Montagna, Elisabetta;De Silvestri, Annalisa;Tinelli, Carmine
    • Nutrition Research and Practice
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    • v.8 no.1
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    • pp.94-102
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    • 2014
  • Diet attrition and failure of long term treatment are very frequent in obese patients. This study aimed to identify pre-treatment variables determining dropout and to customise the characteristics of those most likely to abandon the program before treatment, thus making it possible to modify the therapy to increase compliance. A total of 146 outpatients were consecutively enrolled; 73 patients followed a prescriptive diet while 73 followed a novel brief group Cognitive Behavioural Treatment (CBT) in addition to prescriptive diet. The two interventions lasted for six months. Anthropometric, demographic, psychological parameters and feeding behaviour were assessed, the last two with the Italian instrument VCAO Ansisa; than, a semi-structured interview was performed on motivation to lose weight. To identify the baseline dropout risk factors among these parameters, univariate and multivariate logistic models were used. Comparison of the results in the two different treatments showed a higher attrition rate in CBT group, despite no statistically significant difference between the two treatment arms (P = 0.127). Dropout patients did not differ significantly from those who did not dropout with regards to sex, age, Body Mass Index (BMI), history of cycling, education, work and marriage. Regardless of weight loss, the most important factor that determines the dropout appears to be a high level of stress revealed by General Health Questionnaire-28 items (GHQ-28) score within VCAO test. The identification of hindering factors during the assessment is fundamental to reduce the dropout risk. For subjects at risk, it would be useful to dedicate a stress management program before beginning a dietary restriction.

A comparative study on eating habits and mental health of Korean middle school students according to their bedtime across regions: using data from the 2020-2022 Korea Youth Risk Behavior Survey

  • Sarim Kim;Jiyoung Jeong;Juyeon Kang;Jihye Kim;Yoon Jung Yang
    • Nutrition Research and Practice
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    • v.18 no.2
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    • pp.269-281
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    • 2024
  • BACKGROUND/OBJECTIVES: The objective of this study was to compare dietary habits and mental health among middle school students in urban and rural areas based on bedtime, and to provide evidence supporting appropriate bedtime for Korean middle school students in relation to their healthy dietary habits and mental well-being. SUBJECTS/METHODS: The study population consisted of 25,681 second-year middle school students who participated in the Korea Youth Risk Behavior Survey in 2020-2022. Participants were asked about their bedtime and wake-up time during the past 7 days and were classified into five categories. The study compared the general characteristics, academic factors, dietary habits, and mental health of urban and rural students based on their bedtime. RESULTS: Bedtime was found to be later in the following order: urban female students, rural female students, urban male students, and rural male students. As bedtime got later, the rates of smoking and alcohol consumption increased. Students who went to bed before 11 p.m. had lower academic performance, while rural male students who went to bed after 2 a.m. had lower academic performance. Later bedtime was associated with increased smartphone usage, skipping breakfast, consuming fast food, and drinking carbonated beverages. Later bedtime was also associated with higher perceived stress levels, particularly among students who went to bed after 2 a.m., higher rates of suicidal ideation, experiencing sadness and despair, as well as the prevalence of clinically significant anxiety disorders. CONCLUSION: These results suggest that middle school students who go to bed too late have higher rates of smoking and alcohol drinking, as well as unhealthy eating habits, stress, suicidal ideation, sadness, and anxiety. Therefore, it is necessary to provide educational and social institutional support to promote adequate sleep for the health of adolescents.