• Rubber Technology
• /
• v.13 no.1
• /
• pp.1-9
• /
• 2012

Click chemistry had enjoyed a wealthy decade after it was introduced by K.B.Sharpless and his co-worker on 2001. Since there is no optimized method for synthesis of click polymer, therefore, this paper introduced three click reaction methods such as catalyst, non-catalyst and azide-end capping for fluorene-based functional click polymers. The obtained polymers have reasonable molecular weight with narrow PDI. The polymers are thermally stable and almost emitted blue light emission. The synthesized fluorene-based functional click polymers were characterized to compare the effect of click reaction methods on polymer electro-optical properties as well as device performance on quasi-solid-state dye sensitized solar cells (DSSCs) applications. The DSSCs with configuration of $SnO_2:F/TiO_2/N719$ dye/quasi-solid-state electrolyte/Pt devices were fabricated using these click polymers as a solid-state electrolyte components. Among the devices, the catalyzed click polymer composed device exhibited a high power conversion efficiency of 4.62% under AM 1.5G illumination ($100mW/cm^2$).These click polymers are promising materials in device application and $Cu^I$-catalyst 1, 3-dipolar cycloaddition click reaction is an efficient synthetic methodology.

• Bulletin of the Korean Chemical Society
• /
• v.35 no.12
• /
• pp.3645-3646
• /
• 2014

• The Journal of Korean Physical Therapy
• /
• v.24 no.2
• /
• pp.57-65
• /
• 2012

Purpose: This study was to investigate the effect of biomechanical intervention, based on the custom seating system on the activities of a mouse click for children with cerebral palsy. Methods: Thirteen children with cerebral palsy participated in this study. We compared reaction time and frequency for proper mouse click in the subject's typical position, in addition to an intervention position. The intervention position conformed to the principle and practice of research on promoting the upper-extremity movement and postural control. The intervention position was achieved through an external postural support, which was based on the custom seating system. Results: Reaction time and frequency for proper mouse click were moderately improved in the intervention position, compared with that of the typical position. There was a statistically significant difference between the typical position and that of the intervention position (p<0.05). Conclusion: Results provide evidence of the positive effects of functional seating on the activities of a mouse click for children with cerebral palsy.

• Biomaterials and Biomechanics in Bioengineering
• /
• v.3 no.1
• /
• pp.59-69
• /
• 2016

A surface resisting protein adsorption and cell adhesion is highly desirable for many biomedical applications such as diagnostic devices, biosensors and blood-contacting devices. In this study, a surface conjugated with sulfobetaine molecules was fabricated via the click reaction for the anti-fouling purpose. An alkyne-containing substrate (Alkyne-PPX) was generated by chemical vapor deposition of 4-ethynyl-[2,2]paracyclophane. Azide-ended mono-sulfobetaine molecules were synthesized and then conjugated on Alkyne-PPX via the click reaction. The protein adsorption from 10% serum was reduced by 57%, while the attachment of L929 cells was reduced by 83% onto the sulfobetaine-PPX surface compared to the protein adsorption and cell adhesion on Alkyne-PPX. In conclusion, we demonstrate that conjugation of mono-sulfobetaine molecules via the click chemistry is an effective way for reduction of non-specific protein adsorption and cell attachment.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.11
• /
• pp.3933-3940
• /
• 2011

General, fast, and efficient stitching methods for the synthesis of dendrimers with linear PEG units at a core, as dendritic-linear-dendritic materials, were developed. The synthetic strategy involved the click reaction between an alkyne and an azide. The linear core building blocks, three dialkyne-PEG units, were chosen to serve as the alkyne functionalities for dendrimer growth via click reactions with the azide-dendrons. These three building blocks were employed together with the azide-functionalized Fr$\acute{e}$chet-type dendrons in a convergent strategy to synthesize the Fr$\acute{e}$chet-type dendrimers with different linear core units. Their structure of dendrimers was confirmed by $^1H$ and $^{13}C$ NMR spectroscopy, IR spectroscopy, mass spectrometry, and GPC analysis.

• Polymer(Korea)
• /
• v.39 no.1
• /
• pp.165-168
• /
• 2015

Thermoresponsive polymers were successfully synthesized by a combination of atom transfer radical polymerization (ATRP) and Cu(I)-catalyzed 1,3-dipolar cycloaddition of azide and alkynes (click chemistry). Poly(2-hydroxyethyl methacrylate) (PHEMA) was synthesized by ATRP, followed by introduction of alkyne groups using pentynoic acid, leading to HEMA-alkyne. Homopolymers having secondary amine groups, tertiary amines with hydroxyethyl and hydroxypropyl groups were synthesized by adding 2-azido-N-ethyl-ethanamine, 2-[(2-azidoethyl)amino]ethanol, and 2-[(2-azidoethyl)amino]propanol, respectively, to the PHEMA-alkyne backbone using click chemistry. Molecular weight (MW), molecular weight distribution (MWD), and click reaction efficiency were determined by gel permeation chromatography (GPC) and $^1H$ NMR spectroscopy. The transmission spectra of the 1.0 wt% aqueous solutions of the resulting polymers at 650 nm were measured as a function of temperature. Results showed that the lower critical solution temperature (LCST) could be easily controlled by the length of the hydroxyalkyl groups.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.2
• /
• pp.547-552
• /
• 2011

Azido contained polymers were treated with various substituted N-propargyl tetrazoles in $CH_2Cl_2/H_2O$ at room temperature by Cu-catalyzed [2+3] cycloaddition to afford high yields of the corresponding polymers, possessing both triazole and tetrazole moiety.

• Bulletin of the Korean Chemical Society
• /
• v.35 no.12
• /
• pp.3675-3678
• /
• 2014

• Bulletin of the Korean Chemical Society
• /
• v.32 no.9
• /
• pp.3306-3310
• /
• 2011

A series of novel linear aromatic ether ketone polymers containing triazole units were synthesized by click chemistry and their structures and properties were characterized by FT-IR, $^1H$ NMR, GPC, TGA, DSC and WAXD. The results showed that these polymers exhibited relatively small molecular weights distributions, good thermal stability and solvent-repelling which could have potential applications as engineering thermoplastic.

• Macromolecular Research
• /
• v.15 no.6
• /
• pp.541-546
• /
• 2007

The combination of atom transfer radical polymerization (ATRP) and click chemistry was employed for the efficient preparation of well-defined block copolymers. Bromo terminated poly(methyl acrylate) (pMA-Br) was prepared by an ATRP initiator, ethyl-2-bromoisobutyrate (EBiB). Subsequently, the bromine chain end of pMA-Br was converted to an azide group by simple nucleophilic substitution reaction. ${\alpha}-Alkyn-{\omega}-bromo-functionalized$ polystyrene was also synthesized by ATRP using the alkyn-functionalized initiator, propargyl-2-bromoisobutyrate (PgBiB). In both cases, the conversion was limited to a low level to ensure a high degree of chain end functionality. Then the coupling reaction between the azide end group in $pMA-N_3$ and alkyn-functionalized PgBiB-pSt was performed by Cu(I)catalysis. This coupling reaction was monitored by gel permeation chromatography (GPC). The synthesized block copolymer was characterized by FT-IR, $^1H-NMR$ spectroscopy and $^1H-^1H$ COSY correlation spectroscopy.