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http://dx.doi.org/10.5012/bkcs.2011.32.11.3933

Convergent Synthesis and Characterization of Dumbbell Type Dendritic Materials by Click Chemistry  

Sung, Sae-Reum (Department of Chemistry, Dong-A University)
Han, Seung-Choul (Department of Medical Bioscience, Dong-A University)
Jin, Sung-Ho (Department of Chemistry Education, Pusan National University,)
Lee, Jae-Wook (Department of Chemistry, Dong-A University)
Publication Information
Bulletin of the Korean Chemical Society / v.32, no.11, 2011 , pp. 3933-3940 More about this Journal
Abstract
General, fast, and efficient stitching methods for the synthesis of dendrimers with linear PEG units at a core, as dendritic-linear-dendritic materials, were developed. The synthetic strategy involved the click reaction between an alkyne and an azide. The linear core building blocks, three dialkyne-PEG units, were chosen to serve as the alkyne functionalities for dendrimer growth via click reactions with the azide-dendrons. These three building blocks were employed together with the azide-functionalized Fr$\acute{e}$chet-type dendrons in a convergent strategy to synthesize the Fr$\acute{e}$chet-type dendrimers with different linear core units. Their structure of dendrimers was confirmed by $^1H$ and $^{13}C$ NMR spectroscopy, IR spectroscopy, mass spectrometry, and GPC analysis.
Keywords
Alkyne; Azide; Click reaction; Dendritic-linear-dendritic materials; Dendrimer;
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Times Cited By KSCI : 9  (Citation Analysis)
Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 8
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