• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.18 no.2
• /
• pp.102-107
• /
• 2007

Laryngopharyngeal reflux disease (LPRD) is the result of retrograde flow of gastric contents to the laryngopharynx. Laryngoscopic findings and special questionnaires are first step of diagnosis of LPRD. Empiric trials of Proton pump inhibitor' test (PPI test) is recommended as treatment and diagnosis. However confirmation of reflux is then recommended primarily in patients with persistent symptoms despite acid-suppressive therapy. The 24 hour ambulatory double pH monitoring has been a gold standard method in diagnosis of LPRD even though it has some limitation. The combined multichannel intraluminal impedance and pH monitoring is a new-rising test tool. It can detect acid/non-acid, liquid/gaseous reflux and clearance of refluxate. The water siphon test is also used for diagnosis of LPRD.

• Journal of Pharmaceutical Investigation
• /
• v.25 no.3
• /
• pp.193-204
• /
• 1995

In order to examine the effect of extrahepatic cholestasis induced by common bile duct ligation on the hepatic function, the pharmacokinetics of antipyrine and d-propranolol were investigated in rats. In addition, in an attempt to observe the degree of direct hepatic injury, light and electron microscopic observations and conventional pathologic test using serum were performed. Five days after common bile duct ligation, antipyrine(15 mg/kg) and d-propranolol(3 mg/kg) were intravenously administrated to the rats, respectively. The total clearances of antipyrine and d-propranolol were significantly(p<0.05) decreased. Because hepatic clearance of antipyrine poorly extracted by the liver and that of d-propranolol highly extracted by the liver are respectively dependent on the hepatic intrinsic clearance and the hepatic blood flow, it may be concluded that extrahepatic cholestasis following five days after common bile duct ligation decreased the hepatic intrinsic clearance and the hepatic blood flow. SGPT, SGOT, cholesterol, bilirubin(total bilirubin, direct bilirubin) and alkaline phosphatase were significantly increased(p<0.05). The proliferation of bile ducts was prominent, and degeneration and necrosis of hepatocytes were observed by light microscope. Also, ultrastructurally, bile canaliculi were containing the amorphous materials and losing microvilli, and SER and RER in hepatocytes were dilated and vacuolated.

• Journal of Korean Society of Transportation
• /
• v.30 no.2
• /
• pp.21-27
• /
• 2012

This study deals with the relationships between signal operation and traffic accident of signalized intersections. The objective of this study is to analyze the traffic accident reduction effects on the operation of all-red clearance interval (ARCI). This study gives particular attentions to evaluating the traffic accident reduction effects of ARCI at 37 signalized intersections in Cheongju using before-after evaluation with comparison group. The main results are as follows. First, the number of traffic accidents, fatalities and injuries has changed before operating ARCI and thereafter. Second, the result of before-and-after evaluation with comparison group showed that the number of accidents was reduced by 20.0% and that the number of fatalities and injuries was reduced by 28.0%. Finally, reduction effects from operating ARCI were evaluated to be 6.0~35.0% in the number of accidents and 18.0~37.0% in the number of fatalities and injuries.

• The Korean Journal of Nuclear Medicine
• /
• v.32 no.3
• /
• pp.266-275
• /
• 1998

Purpose: We measured pulmonary epithelial permeability by $^{99m}Tc-DTPA$ radioaerosol clearance in patients with diabetes and correlated with the presence of microangiopathy to understand the pathophysiology of pulmonary microangiopathy and evaluate $^{99m}Tc-DTPA$ radioaerosol clearance as a diagnostic test to assess pulmonary microangiopathy. Materials and Methods: We performed $^{99m}Tc-DTPA$ radioaerosol scan in 10 normal subjects, 10 asymptomatic smokers, 20 diabetic patients without history of smoking (10 with microangiopathy, 10 without microangiopathy). $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) was calculated, then compared with the result of chest radiography and pulmonary function test. Results: Chest radiography and pulmonary function test were normal in all subjects. There were no significant difference of clinical or laboratory characteristics between these groups except age. The diabetic patients with microangiopathy were significantly older (p<0.05). The $T_{1/2}$ of normal subjects and asymptomatic smokers were significantly different ($65.2{\pm}23.7min$ vs $39.6{\pm}9.8min$, p<0.05). For diabetic patients with microangiopathy, the $T_{1/2}$ was $90.5{\pm}46.5min$ and significantly delayed when compared with those of normals and asymptomatic smokers (p<0.05). However, the $T_{1/2}$ of diabetic patients without microangiopathy, $70.0{\pm}12.7min$, was not significantly different from those of normals or asymptomatic smokers (p>0.05). No significant correlation was found between the $T_{1/2}$ and spirometric parameters including DLco, FVC, $FEV_1,\;FEV_1/FVC$ (%) and $FEF_{25-75%}$ in all subjects, and between the $T_{1/2}$ and duration of diabetes ;in diabetic patients. Conclusion: Eventhough the influence of age can't be excluded, delayed $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) in diabetic patients with microangiopathy indicates decreased pulmonary capillary permeability as one of the pathophysiologic results of pulmonary microangiopaththy. Further studies are needed in larger number of age matched control and diabetic patients to evaluate the diagnostic efficacy.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 1991.04a
• /
• pp.225-236
• /
• 1991

Thermoleastoplastic analysis of a typicaldevice consisting of tube and moving part having an initial clearance in between, which is subjected mechanical and thermalload, has been carried out toexamine the cause of malfunction mainly at hightemperature condition, and to improve the design. Permant deformation, extraction force, and stress distributions are discussed by using finite element method. The extraction energy can be remarkably reduced by changing the configuration of the cylinder from straight-type to ta[er-type and this effect has been proved by sustained cyclic test.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.28 no.12
• /
• pp.1864-1870
• /
• 2004

A spot welded structures have an influence on a diverse climatic situation, for instance temperature, humidity and precipitation. In addition factors of environmental pollution such as acid rain, that courses corrosion, have the tendency to increase. But spot welded structures strength is affected by humidity and environment temperature. Therefore, it is important to evaluate effect of temperature and water immersion on strength properties of spot welded part. In this study, the strength distribution of spot welded plates is evaluated the environmental temperature of zinc coated steel plates. Test is conducted with welded part immersed in distilled and synthetic sea water. Specimens are immersed into water for 10, 100, 500 and 1000 hours to evaluate the offsets of water immersion time on tensile-shear strength under the conditions of -40, 0, 20 and 5$0^{\circ}C$. From this result, spot welded specimens with 5 mm clearance have lower tensile-shear strength in the distilled water or synthetic sea water than without clearance. And they have lower tensile-shear strength under -4$0^{\circ}C$ and over 5$0^{\circ}C$.

• Journal of Advanced Marine Engineering and Technology
• /
• v.17 no.1
• /
• pp.66-72
• /
• 1993

The brazing of Al to Al using Al-Si alloy filler metal was performed under different bonding conditions such as ratio of lap length to plate thickness, surface roughness and joint clearance of the lap joint. The adopted thickness of the base metal in this experiments were two kinds of 4mm and 7mm which were most commonly used in various field. Influence of several bonding conditions of Al/Al joint was quantitavely evaluated by bonding strength test, and microstructural analysis at the interlayer were performed by optical microscope. From above experiments, the optimum bonding conditions of the brazing bonding of Al/Al using Al-Si alloy filler metal was determined. The major results obtained are as follows. 1) The fracture occurs at brazed joint in the conditions of that the ratio of lap length to plate thickness is less than 2 in case of 7mm plate thickness. 2) The ratio of lap length to plate thickness which the fracture occurs at base metal is decreased with the decreasing of the plate thickness. 3) The joint strength is not affected by the surface roughness and joint clearance of the brazed part. 4) The heat-treatment of the brazed joint contribute to eliminate the boundary between the base metal and filler metal. However, the joint strength is not affected by the heat-treatment.

• Transactions of Materials Processing
• /
• v.14 no.1 s.73
• /
• pp.37-42
• /
• 2005

In order to invstigate the influence of die design variables on the quality of the sheared surface in cutting of sandwich sheet metals, the cut-off operation is carried out, which is the typical shearing process in sheet metal forming technology. For experiments we made the cut-off die which can be easily adjusted for die design variables such as blankholding force, pad force and clearance. The sandwich sheet metals considered are clad304(STS304-Al1050-STS304) and anti-vibration sheet metal. The shearing process is visualized by the computer vision system installed in front of the cut-off die and the sheared surface is measured and quantitatively compared with the help of the optical microscope after cut-off operation. From test results it is shown that the shearing mechanisms are different according the material of which sandwitch sheet metal is composed. The influence of die design variable is explored and we found optimal conditions for both sandwich sheet metals. It is expected that this investigation can be utilized to get the better sheared surface.

• Proceedings of the KIEE Conference
• /
• 2005.07a
• /
• pp.521-523
• /
• 2005

A Jumper wire is currently used to connect each fixed power line on both sides of dead end tower for overhead transmission line, but in case of a jumper wire swing under circumstances of typhoon, etc. and the air clearance is deficient then a flashover fault may Happen. Now the angle tower has the jumper support string to prevent a swing of jumper wire and to secure the air clearance between jumper wire and tower main body, but the flashover fault by swing of jumper wire was happened yl times across all over the country, because of the typhoon 'Rusa' in year 2002 and 'Maemi' in year 2003. This paper presents the design and development of 'Counter Weight' which enables to keep the swing angle of jumper wire under 40 degree in design condition to prevent a flashover fault by swing of jumper wire by a high wind pressure load in case of typhoon and have completed a mechanical and electrical characteristic test.

• Journal of the Society of Naval Architects of Korea
• /
• v.41 no.6
• /
• pp.24-32
• /
• 2004

The effects of guide vanes and tip clearances on the characteristics nf axial flow fans are investigated both computationally and experimentally. Performance test of fans carried out in full scale shows considerable effects of tip clearance between rotor tip and duct on the characteristics of fans. The tested results are compared with the computation based on the finite volume method to solve the Navier-Stoke equations with $textsc{k}$-$\varepsilon$ turbulence model. The comparison shows good agreements between experimental and computational results. In addition, the effects of shape of guide vanes are numerically studied. The results show that increased volume of separated region around the guide vane reduces the recovery of tangential component of kinetic energy in the wake, resulting in loss of efficiency