• 한국임상약학회지
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• 제26권4호
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• pp.298-305
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• 2016

Background: This study is to investigate the prescription patterns and factors related to the number of medications treating chronic obstructive pulmonary disease (COPD) in patients under 65 years old according to GOLD guidelines. Methods: We retrospectively analyzed the medical records of patients aged 40-64 years with a diagnosis of COPD from January to March 2016. Patients were classified by combined assessment of COPD (grades A, B, C, D) using spirometry, exacerbation history, mMRC, and/or CAT results. We analyzed prescribed medications, treatment options and factors related to the numbers of COPD medications. Results: The total number of prescriptions were 251. About 35.5% of patients were classified as GOLD A, 34.2% as GOLD B, 17.1% as GOLD C and 13.2% as GOLD D. Inhaled bronchodilator was prescribed for 86.9% of patients and the most frequent COPD medication was long-acting muscarinic antagonist (LAMA) followed by inhaled corticosteroids/long acting beta agonist (ICS/LABA). The majority of low risk patients (GOLD A/B) were prescribed a monotherapy with LAMA or LABA. For high risk patients (GOLD C/D), combination treatment with ICS+LAMA+LABA was mostly prescribed. The 21.2% of patients in GOLD D received systemic corticosteroid. The average number of medications per prescription was 3.7, and this number increased with increasing COPD grade, COPD duration and lung function reduction ($FEV_1$, $FEV_1/FVC$). Conclusion: Generally high adherence to GOLD guideline recommendations was reported. Given the progressive nature of the disease, results suggest that closer attention to respiratory symptoms for early detection, diagnosis, and appropriate treatment of COPD is warranted.

• 대한의료기공학회지
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• 제11권1호
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• pp.284-325
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• 2009

This study aims to investigate the educational significance in modern education by analysis on the contents of taboo in the Korean traditional prenatal education. For this study, the concrete matters are prepared for investigation as follows: First, the contents of prenatal education are analyzed with special reference to the Chinese bibliography and the Korean bibliography related to its own traditional prenatal education. Second, the contents of taboo in prenatal education are broadly classified into Chun-ki(天忌), Chi-ki(地忌), and In-ki(人忌), and in turn, In-ki is classified into taboo related to clothing, taboo related to food, Taboo related to housing, and man's taboo, and all of them are interpreted. Third, the characteristics of taboo in the Korean traditional prenatal education and its principle are analyzed, and its significance is researched from the modern educational point of view. This study attempts to classify the contents of taboo into Chun-ki, Chi-ki, In-ki, and man's taboo based upon analysis of the documentary records related to the traditionary prenatal education in China and Korea for the successful investigation. The characteristic such as common discipline, the time limit and prevention are induced on the basis of this investigation, and its modern educational significance as follows: First, prenatal education must be conduced as a part of youth education and preparatory parents education for the married couple. Second, man or husband plays a very important role of practising taboo in prenatal education. Third, taboo in prenatal education is very suggestive in the aspect of human relationship and mental health of the pregnant woman. Fourth, it prevents her obesity and strain. Fifth, the scientific proof and education of taboo related to food must be needed.

• Asian-Australasian Journal of Animal Sciences
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• 제15권8호
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• pp.1178-1181
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• 2002

Records from a total of 202 crossbred pigs were classified by their ear type and coat color to examine the presence of interrelationships with growth performances. Crossbred pigs were F2 generations of full sib family out of ten Landrace sows bred by 5 Korean domestic boars. Heavily drooped ear type was predominant, 195 out of 202 pigs over the other two types (1 straight and 6 slightly drooped). Coat colors were classified as four categories, all white, all black, dominant white or dominant black. Ratio among coat color categories did not fall within Mendelian principle of independence regarding two loci involved. There was dependency between ear type and coat color. However, due to rarity of ear types other than heavy drooped, dependency comes from distribution of those rare ear types. Three least squares models to test the effect of ear type and coat colors on growth performances were analyzed. First model analyzed effects on birth weight, body weight at 3 and 6 weeks and ADG' before weaning and between 3 and 5 weeks of age. This model included sex in addition to ear type and coat color. Second model analyzed postweaning growth traits (initial weight, final weight and ADG between these periods) upon initiation of performance testing. This model included effects of sex, test group and start age (as a covariate) in addition. Third model was fit for fasted weight before slaughter and included the effects of sex, test group and age at slaughter (as a covariate). The effects of sex and ear type were not significant source of variation for all traits. Test group was a significant source of variation for all the postweaning traits. Effect of coat color was not significant until the initiation of performance testing and became significant then after. Least squares means of dominantly black pigs were significantly lower than the other three coat colored pigs in final weight around 195 days of age and in ADG from the start of performance test and final weight measure.

• Archives of Plastic Surgery
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• 제42권5호
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• pp.608-613
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• 2015

Background The purpose of this study was to compare postoperative morbidities and functional outcomes of pectoralis major myocutaneous (PMMC) flap and cutaneous free flap reconstruction approaches in hypopharyngeal squamous cell carcinoma patients. Methods We retrospectively reviewed records from 99 patients who underwent hypopharyngeal reconstruction with a cutaneous free flap (n=85) or PMMC flap (n=14) between 1995 and 2013. Morbidity was classified into hospitalization, medical, or flap-related complications. Functional outcomes were classified into oral re-alimentation and decannulation time. Results The overall flap-related complication rate was higher in the PMMC flap group (n=8, 57.1%; P=0.019), but the medical morbidity rate was higher in the cutaneous free flap group (n=68, 80%; P=0.006). The rate of pneumonia was higher in the cutaneous free flap group (n=48, 56.5%; P=0.020). Pulmonary premorbidity was the variable most significantly associated with pneumonia (odds ratio=3.012, P=0.012). There was no statistically significant difference in oral re-alimentation and decannulation time between the two groups. Conclusions Although the functional superiority of free flaps has been reported in many studies, our results do not support this hypothesis. One limitation of our study is the relatively smaller flap size and fewer PMMC flap cases compared with the cutaneous free flap group. The low postoperative medical morbidity incidence rate in the PMMC flap group was clinically significant; however, the free flap group had more flap-related complications. Thus, PMMC flaps should be considered a viable option, especially for patients with pulmonary premorbidities.

• Journal of Trauma and Injury
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• 제22권1호
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• pp.29-36
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• 2009

Purpose: The purpose of this study was to analyze the characteristics and severity of wrist injuries in snowboarding. Methods: December 2005 to February 2008, Snowboarders who experienced wrist injures were included in this study. On the basis of the medical records and radiographic evaluation, the severity of distal radius fracture was classified according to the Arbeitsgemeinschaft fur Osteosynthesefragen/Association for the Study of Internal Fixation (AO/ASIF) classification. Results: Most of the injured snowboarders were a either of the beginner (35 cases, 46.1%) or the intermediate (27 cases, 35.5%) level. The most common cause of injury in snowboarding was a slip down (60 cases, 78.9%). Comminuted and articular fractures classified as AO types A3, B, and C, which required surgical reduction, made up 42.3% of the distal radial fractures in snowboarders. When we analyzed the differences in severity between the educated and the non-educated groups, an A2 type injury in the AO classification was the most common type of injury in the educated group (20 cases, 38.5%), it means less severe fractures ocurred in the educated group (p=0.045). The most frequent injury mechanism of fractures was slip down (48 cases, 63.2%), and a slip down backwards was the dominant type of slip down (36 cases, 75.0%) (p=0.031). Conclusion: Among the snowboarders in this study who suffered self-down injury to the wrist, more fractures were associated with a backwards slip down than with a forward slip down due to over extension. For educated snowboarders the severity of fracture was lower than it was for uneducated snowboarders.

• Journal of Community Nutrition
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• 제6권1호
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• pp.35-41
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• 2004

Cardiovascular disease has the highest mortality rate in South Korea. Previous studies have reported that serum cholesterol level relates to intake of dietary fat and cholesterol. Therefore, in this study we developed a semiquantitative food frequency questionnaire (FFQ) for Koreans with a high-risk of hypercholesterolemia and to validate the FFQ. Semiquantitative FFQ, which includes 160 food items, reflects intakes of energy, fat, saturated fatty acid (SFA), monounsaturated fatty acid (MUPA), polyunsaturated fatty acid (PUPA) and cholesterol. We chose food items from the previous study of our research group (Suh 1999) which reported a nutritional status of Korean adults with normocholesterolemia, borderline and hypercholesterolemia. To validate the FFQ, we compared the results of the FFQ with those of a 3-day food record using a paired t-test. In addition, we calculated Pearson's and Spearmen's correlation coefficients. Intakes assessed by the FFQ and a 3-day food record were classified into quartile and the degree of agreement was obtained. Fifty-five participants responded for the validation study by completing both the FFQ and a 3-day food record. Pearson's correlation coefficients between estimated intakes by respective methods for energy, fat, SF A, MUPA, PUPA and cholesterol were 0.32,0.41,0.37,0.41,0.37 and 0.21, respectively. Spearman's correlation coefficients of energy, fat, SF A, MUPA, PUPA, cholesterol were 0.31, 0.44, 0.39, 0.46, 0.46, and 0.37, respectively. Nutrient densities in 1000kcal were compared. Pearson's correlation coefficient of cholesterol density increased and other values were similar with original values. The average degree of agreement was 67％ that intakes of energy, fat, SF A, MUPA, PUPA and cholesterol assessed by the FFQ and 3-day food records were classified within the same and the adjacent quartile. On the average, 8％ were misclassified into the extreme opposite quartile. The average of weighted kappa was 0.46. In conclusion, the FFQ developed in this study is considered to be a reliable tool to assess nutrient intakes for Koreans with a risk of hypercholesterolemia because the FFQ reflects the intakes of energy, fat, SFA, MUFA, PUPA, and cholesterol.

• 한국학교보건학회지
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• 제9권2호
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• pp.185-195
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• 1996

This study attempts to discover ways to prevent and cope with stress m primary school students, Specific, ally, we wish to investigate the sources of stress and to identify the variance and frequency of coping methods which have been used by the subjects. After examining the school children's list of items about stress and coping strategies by on open structure method, subjects ranked the seventy of stressor's and frequency of a coping strategies by closed structure method. A survey was done of 720 students who were from the 4th to 6th grade in 4 primary schools in the Chonbuk area from April 1st to May 30th, 1995. The major results obtained from this study were the following. 1. The sources of stress bad were classified in 57 items Among the 57 items, 'were school records' 'illness of parents' 'death of family members' 'meetings with trouble makers' ranked high ranking in the stress ratings. 2. Severity of stress. the mean total stress scores were 186.4 with 285 as the highest score. 3. The kinds of coping with stress using were classified in 35 items, Among the 35 items, 'wandering and walking alone' 'mood getting out of the in any way' 'trying to forget the stressor' 'were among the highest scored. 4. Frequency of coping with stress: mean total stress coping scores were 67.9 with 140 as the highest score. 5. Difference m stress and coping strategies between sex, age, living district and religion groups were examined. 1) Significant variables influencing stress scoring were sex (t=-2,29, p<.001) and grade (F=6.33, p<.001). 2) Significant variables influencing stress coping practice were residence (t=1.94, p<.05), sex (t=-3.17, p<.002) and religion (F=5,95, p<.0001).

• Advances in pediatric surgery
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• 제14권2호
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• pp.164-172
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• 2008

The survival rate for rhabdomyosarcoma (RMS) has significantly improved after the introduction of combined multimodality treatment. We report the 20-year treatment outcome of pediatric rhabdomyosarcoma in a single institution. The medical records of 16 patients treated for rhabdomyosarcoma between December 1986 and August 2007 at the Department of Pediatric Surgery, Seoul National University Children's Hospital, were retrospectively reviewed. Mean age at diagnosis was 7.1 years (range: 1.3 -14.2 years). Retroperitoneum was the most common primary site (n=7, 43.8 %), and embryonal type was predominant (n=11, 6 %). Before the treatment, most patients were in advanced TNM stage (stage III 50 %, IV; 25 %). The patient distribution according to the Intergroup Rhabdomyosarcoma Study Clinical Grouping System (IRS-CGS) was as follows; Group I 31.3 %, Group II 12.5 %, Group III 31.3 % and Group IV 25 %. Patients were classified into three groups according to the extent of resection of the primary tumor; complete resection (CR, n=5; 31.3 %), gross total resection (GTR, n=7; 43.8 %) and incomplete resection (IR, n=4; 25 %). Recurrence was observed in 9 patients (56.3 %) while there was no recurrence in CR patients. All patients with recurrence were identified as moderate or high-risk according to the IRS-V Risk Group. Pre-treatment TNM stage of RMS in our institution was advanced with aggressive clinical feature, however postsurgical conditions according to IRS-CGS were similar to the previous reports by IRS. This suggests that down-staging of IRS-CGS was achieved with multimodality treatment with CR or GTR. It also suggests that complete resection is the most important prognostic factor in the treatment of RMS in children. Patients classified as moderate or high-risk need close follow-up due to high recurrence rate. In case of localized recurrence, better outcome may be achieved with multimodality treatment including limited surgery.

• 한방안이비인후피부과학회지
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• 제17권3호
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• pp.1-7
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• 2004

Objectives: In order to establish a base for proper treatment and management of patients with dermal problems through correct diagnosis, I considered the naming rule for dermatology in Oriental Medicine, referring to the dermatology literature compared to western medicine. In addition, this paper examines the characteristic classification of dermatology. Methods: I examined the naming rule of dermatology in Oriental Medicine and then compared the disease names in Oriental and Western medicine and the characteristic classification of dermatology referred to the records. Results: The dermal diseases have been named according to their colors and morphologies, causes, progress of symptoms, recurrent sites, the character of distribution, recurrent seasons, ages, the character of patients' jobs and locations. Sometimes some have been named by referring to their main morphologies, sites, causes, colors and seasons synthetically. However it was found some names for dermal diseases, even though the same diseases, had been named differently according to for example: historical times, condition of locations and the quality of doctors whose process of naming developed and changed over time. The relationship between Oriental and Western medicine of each name for dermal diseases is basically divided into 5 types: same names - same diseases; same names but different diseases; same diseases but different names; one disease with multiple names; and one name with multiple diseases. Considering the methods of classification, these were generally achieved according to their places of origin. It is a method unique to Oriental medicine that we classified some dermal diseases into 疥, 癬, 瘡, 風, 丹, 疱, 疹, 癰, 痘, 疽 and so on and it is very easy to diagnose which part they belong to. This was classified by putting first the causes of diseases; for instance: viruses, bacteria, fungi. Sometimes, however there was a problem, connected to the classification of morphology. Conclusions: I suggest that we need to unify and refine dermatological terms in Oriental Medicine in order to establish a base for proper treatment and management of patients with dermal problems through correct diagnoses.

• 대한본초학회지
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• 제36권5호
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• pp.29-36
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• 2021

Objectives : The purpose of this study was to fix the synonyms, origin, formation mechanism, description, and efficacy of Hwangnapchim in Elucidation of Materia Medica. Methods : Through searching histories and herbal classics, We categorized the contents, and compared with Aquilariae Lignum Resinatum. Results : The synonyms of Hwangnapchim were classified by 3 categories : Napchimhyang-type, Ganamhyang-type and Ginamhyang-type. In early period, it was called by Napchimhyang-type, named after its description that was similar to beeswax. Afterward it was called by Ganamhyang-type or Ginamhyang-type, because of the name "Kynam" that was called by in its producing region. And there were records of producing region of Vietnam, Cambodia, and being from abroad, while those of Vietnam were most frequent. According to custom duties of Ming Dynasty, Hwangnapchim was 17.5 times as expensive as Agarwood. Hwangnapchim shared main producing region, original plant, and process of formation with Agarwood. Therefore, its original plant was Aquilaria crassna, but added honey during formation process. Hwangnapchim was classified 5 types according to its description, the highest quality was Yu-gyeol, resembled beeswax, and easily recovered if get a scar. Hwangnapchim had a fragrance at room temperature, a spicy flavor, and the efficacy of blocking urine and feces. Conclusions : These results showed that Vietnam was major producing area of Hwangnapchim, and that it shared same origin with Agarwood, but it had different description, efficacy, and higher prices because of being added honey during formation.