• Animal Bioscience
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• 제35권6호
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• pp.791-803
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• 2022

Genome/gene-editing (GE) techniques, characterized by a low technological barrier, high efficiency, and broad application among organisms, are now being employed not only in medical science but also in agriculture/veterinary science. Different engineered CRISPR/Cas9s have been identified to expand the application of this technology. In pig production, GE is a precise new breeding technology (NBT), and promising outcomes in improving economic traits, such as growth, lean or healthy meat production, animal welfare, and disease resistance, have already been documented and reviewed. These promising achievements in porcine gene editing, including the Myostatin gene knockout (KO) in indigenous breeds to improve lean meat production, the uncoupling protein 1 (UCP1) gene knock-in to enhance piglet thermogenesis and survival under cold stress, the generation of GGTA1 and CMP-N-glycolylneuraminic acid hydroxylase (CMAH) gene double KO (dKO) pigs to produce healthy red meat, and the KO or deletion of exon 7 of the CD163 gene to confer resistance to porcine reproductive and respiratory syndrome virus infection, are described in the present article. Other related approaches for such purposes are also discussed. The current trend of global regulations or legislation for GE organisms is that they are exempted from classification as genetically modified organisms (GMOs) if no exogenes are integrated into the genome, according to product-based and not process-based methods. Moreover, an updated case study in the EU showed that current GMO legislation is not fit for purpose in term of NBTs, which contribute to the objectives of the EU's Green Deal and biodiversity strategies and even meet the United Nations' sustainable development goals for a more resilient and sustainable agri-food system. The GE pigs generated via NBT will be exempted from classification as GMOs, and their global valorization and commercialization can be foreseen.

• International Journal of Computer Science & Network Security
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• 제22권5호
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• pp.175-181
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• 2022

COVID-19 is an acute respiratory syndrome that affects the host's breathing and respiratory system. The novel disease's first case was reported in 2019 and has created a state of emergency in the whole world and declared a global pandemic within months after the first case. The disease created elements of socioeconomic crisis globally. The emergency has made it imperative for professionals to take the necessary measures to make early diagnoses of the disease. The conventional diagnosis for COVID-19 is through Polymerase Chain Reaction (PCR) testing. However, in a lot of rural societies, these tests are not available or take a lot of time to provide results. Hence, we propose a COVID-19 classification system by means of machine learning and transfer learning models. The proposed approach identifies individuals with COVID-19 and distinguishes them from those who are healthy with the help of Deep Visual Embeddings (DVE). Five state-of-the-art models: VGG-19, ResNet50, Inceptionv3, MobileNetv3, and EfficientNetB7, were used in this study along with five different pooling schemes to perform deep feature extraction. In addition, the features are normalized using standard scaling, and 4-fold cross-validation is used to validate the performance over multiple versions of the validation data. The best results of 88.86% UAR, 88.27% Specificity, 89.44% Sensitivity, 88.62% Accuracy, 89.06% Precision, and 87.52% F1-score were obtained using ResNet-50 with Average Pooling and Logistic regression with class weight as the classifier.

• Asian-Australasian Journal of Animal Sciences
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• 제33권7호
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• pp.1202-1208
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• 2020

Objective: The aim of this study was to identify a distribution pattern of meat quality grade (MQG) as a function of carcass yield index (CYI) and the gender of Hanwoo (bull, cow, and steer) to determine the optimum point between both yield and quality. We also attempted to identify how pre- and post-deboning variables affect the gender-specific beef quality of Hanwoo. Methods: A total of 31 deboning variables, consisting of 7 pre-deboning and 24 post-deboning variables from bulls (n = 139), cows (n = 69), and steers (n = 153), were obtained from the National Institute of Animal Science (NIAS) in South Korea. The database was reconstructed to be suitable for a statistical significance test between the CYI and the MQG as well as classification of meat quality. Discriminant function analysis was used for classifying MQG using the deboning parameters of Hanwoo by gender. Results: The means of CYI according to 1+, 1, 2, and 3 of MQG were 68.64±2.02, 68.85±1.94, 68.62±5.88, and 70.99±3.32, respectively. High carcass yield correlated with low-quality grade, while high-quality meat most frequently was obtained from steers. The classification ability of pre-deboning parameters was higher than that of post-deboning parameters. Moisture and the shear force were the common significant parameters in all discriminant functions having a classification accuracy of 80.6%, 71%, and 56.9% for the bull, cow, and steer, respectively. Conclusion: This study provides basic information for predicting the meat quality by gender using pre-deboning variables consistent with the actual grading index.

• 해양환경안전학회지
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• 제29권2호
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• pp.230-237
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• 2023

코로나 19 팬데믹 및 기후 변화 등으로 전 세계적으로 필수적인 생필품과 자원의 품귀 이슈가 지속해서 발생하고 있다. 이러한 현상을 극복하고자 교역량의 수요가 갑자기 증가하였으며 이 결과 컨테이너선의 운임이 대폭 상승하였다. 컨테이너선의 크기 변화는 1960년대 1,500TEU(twenty-foot equivalent unit)를 시작으로 2021년에는 24,400TEU로 대형화가 진행되고 있다. 컨테이너 적재 능력의 향상은 라싱브릿지 구조의 대형화와 긴밀하게 연관되어 있고, 안전한 컨테이너 고박 및 항해 시 발생하는 다양한 외력 하중에 안전한 구조설계를 해야 한다. 현재 주요 선급에서는 라싱브릿지 구조 안전성을 평가할 수 있는 구조해석 기반의 지침서를 배포하고 있으나, 허용기준 및 평가 방법이 달라서 설계 시 엔지니어들에게 혼선을 주고 있다. 본 연구에서는 결과에 영향을 줄 가능성이 큰 주요 변수들(모델링 범위, 오프닝 고려 여부, 메쉬 크기) 변화에 따른 강도 변화 특성을 정리하였다. 이 결과를 바탕으로 저자들은 합리적인 구조해석 기반 평가에 대한 검토사항을 제안하였고, 추후 선급 기준 개정 시 참고가 될 수 있을 것으로 기대한다.

• Journal of Ship and Ocean Technology
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• 제3권4호
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• pp.35-51
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• 1999

Fatigue strength assessment procedures have been implemented in the ship design rules by many classification societies. However, a large variation tin the details of the different approaches exists in practically all aspects influding load history assessment, stress evaluation and fatigue strength assessment. In order to assess the influences of thesd variations on the prediction of fatigue lives. a comparative study is organized by the ISSC Committee III.2 Fatigue and Fracture. A pad detail on the top of longitudinal hatch coaming of a panamax container vessel is selected for fatigue calculation. The work described in this paper is one set of results of this comparative study in which the ABS dynamics approach is applied. Through this analysis the following conclusions can be drawn. (1) With the original ABS approach, the fatigue life of this pad detail is very low, only 2.398 years. (2) The treatment of the stillwater bending moment in the ABS approach might be a source of conservatism. If the influence of stillwater bending moment is ignored, then the fatigue life for this pad detail is 7.036 years. (3) The difference between the nominal stress approach and the hot spot stress approach for this pad detail is about 26%.

• Asian-Australasian Journal of Animal Sciences
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• 제21권5호
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• pp.617-623
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• 2008

A fine-mapping method exploiting linkage disequilibrium was used to detect quantitative trait loci (QTL) on the X chromosome affecting milk production, body conformation and productivity traits. The pedigree comprised 22 paternal half-sib families of Black-and-White Holstein bulls in the Netherlands in a grand-daughter design for a total of 955 sons. Twenty-five microsatellite markers were genotyped to construct a linkage map on the chromosome X spanning 170 Haldane cM with an average inter-marker distance of 7.1 cM. A covariance matrix including elements about identical-by-descent probabilities between haplotypes regarding QTL allele effects was incorporated into the animal model, and a restricted maximum-likelihood method was applied for the presence of QTL using the LDVCM program. Significance thresholds were obtained by permuting haplotypes to phenotypes and by using a false discovery rate procedure. Seven QTL responsible for conformation types (teat length, rump width, rear leg set, angularity and fore udder attachment), behavior (temperament) and a mixture of production and health (durable prestation) were detected at the suggestive level. Some QTL affecting teat length, rump width, durable prestation and rear leg set had small numbers of haplotype clusters, which may indicate good classification of alleles for causal genes or markers that are tightly associated with the causal mutation. However, higher maker density is required to better refine the QTL position and to better characterize functionally distinct haplotypes which will provide information to find causal genes for the traits.

• Journal of Advanced Marine Engineering and Technology
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• 제31권3호
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• pp.215-223
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• 2007

When the propulsion shafting system of marine diesel engine is designed. the vibratory stresses on shafts should be reviewed and be satisfied with limits which are laid down by classification societies In addition. the torsional vibration aspects for crankshaft of main engine are requested to be checked by engine designers. Especially. for the 4, 5, and 6-cylinder engines. the 2nd order moment compensator(s) may be installed to compensate the external moments of engine and not to excite the hull girder vibration. This moment compensator which is mounted on fore and/or after-end of engine is driven by the roller chain drive for some of MAN 2-stroke diesel engines. While the engine is running, the roller chain Is worn down, which causes the extension of roller chain. The chain therefore should be checked and tightened by periods in order to keep its functionality. However. when the torsional angular acceleration of chain drive exceeds the certain limit. the chain will suffer the excessive slack and transverse vibration. This may cause fatigue, wear or damage on the chain and the chain ultimately may be broken. The research object of this thesis is to review factors which affect the angular acceleration of chain drive and to find out how to decrease the angular acceleration of driving chain by checking factors which have a major contribution to acceleration reduction using the statistical method of DOE(design of experiment), correlation analysis and regression analysis methods.

• 한국소음진동공학회논문집
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• 제25권12호
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• pp.815-821
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• 2015

Maritime safety has been more critical recently due to the occurrence of shipboard accidents involving prime movers. As such, the propulsion shafting design and construction plays a vital role in the safe operation of the vessel other than focusing on being cost-efficient. Smaller vessels propulsion shafting system normally install high speed four-stroke diesel engine with reduction gear for propulsion efficiency. Due to higher cylinder combustion pressures, flexible couplings are employed to reduce the increased vibratory torque. In this paper, an actual vibration measurement and theoretical analysis was carried out on a propulsion shafting with V18.3L engine installed on small car-ferry and revealed higher torsional vibration. Hence, a rubber-block type flexible coupling was installed to attenuate the transmitted vibratory torque. Considering the flexible coupling application factor, reduction gear stability due to torque variation was analyzed in accordance with IACS(International Association of Classification Societies) M56 and the results are presented herein.

• Journal of Welding and Joining
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• 제34권1호
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• pp.47-53
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• 2016

WPS/PQR is the essential documents for shipbuilding welding. WPS is the document containing the information related to welding procedure and PQR is the record of approval for welding procedure. Both documents should be approved by the ship owners and the classification societies. It is very important to manage these documents because the welding procedure using these documents could not be carried out before they are approved. Database is an useful tool to manage these documents. It can manage a number of documents and show the processing status of WPS/PQR documents. In this study, all documents related to WPS/PQR documents were investigated and analyzed in the viewpoint of DB. An appropriate DB system was designed for WPS/PQR and the related documents on the basis of CBD methodology. The DB system could make WPS/PQR documents easily and shortly. The grasp of the processing status of WPS/ PQR could help the good management of fabrication schedule in shipbuilding.

• 대한산업공학회지
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• 제19권2호
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• pp.83-93
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• 1993

Conventional computer programs developed and used by practicing engineers can be considered to contain expert knowledge and design experience. If these conventional programs are converted into expert systems, the difficult and time consuming process of knowledge acquisition can be simplified. Also the constructed knowledge-base can have higher confidence level than that constructed by the usual knowledge acquisition method of interviews. An existing computer program which is being used by ship structural designers has been reformulated as a design expert system by applying an expert system development shell-Nexpert. Utilizing the callable interface provided by the development shell, external design tools have also been integrated. The interfaced external functions are a graphical user interface (GUI) for the design process control, and graphics functions for the visualization of design results. It is observed that the developed system for design support is useful in two aspects. The trace-back function shows what portion of design rules are applied in arriving at certain design decisions. Also the knowledge-base can be conveniently updated as design rules of the classification societies are updated.