• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.3
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• pp.61-70
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• 2012

Objectives: In this study, the author aimed to evaluate the effect of BuOH fraction(YK) from Cinnamomum loureirii on osteoblast proliferation in murine rat calvarial cells. Methods: The osteoblast separated from murine calvariae was cultivated for 10 days and evaluated the cell function. After the addition of YK on the culture medium, we determined the effect of YK on the cell proliferation, alkaline phosphatase activity, apoptosis of the cultivated osteoblast, protein synthesis and collagen synthesis. Results: YK increased the proliferation of rat calvarial osteoblast. YK increased ALP activity of rat calvarial osteoblast. YK did not change the survival rate of rat calvarial osteoblast. YK increased protein synthesis of rat calvarial osteoblast. YK increased collagen synthesis of rat calvarial osteoblast. Conclusions: This study suggests that YK might improve the osteoporosis resulted from augumentation of osteoblast proliferation.

• Herbal Formula Science
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• v.20 no.2
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• pp.165-176
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• 2012

In pathologically analyzing, 'Qi(氣)' is fall downed 'Zheng-Qi(正氣; Base energy of human body)' or 'Wai-Gan-Xie-Qi(外感邪氣; poisoned energy from outside of human body)'. And all extroverted symptoms from this 'Qi(氣)' is 'Shang-Chong(上衝)'. Also this symptom's basic mechanism is deficiency of 'Zhong-yang(中陽; basic active energy acting pivot)' by non-proper 'Xia-fa(下法; treatment way getting out focus to down side)' at early days of 'Tai-Yang-bing (太陽病; Primary stage symptoms when the cold energy of the outside tresspasses the external layer of body)'. And comparing herbs in medicines for treating 'Shang-Chong(上衝)' in Shang han lun with Japanese in Shang-han medical practitioner's view, there is 'Ping-Chong(平衝; Supress out bursting energy)''s effect when use 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' for mass dosage. Based on these, 'Qi-Shang-Chong(氣上衝)' means all of the symptom's aspects which called 'Yang(陽)''s aspect that is extrovesity, dynamic and imminent by results of the experiment about Cinnamaldehyde which are the main ingredients of 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' and clinical data of 'Gui-zhi-tang(桂枝湯)'.

• The Plant Pathology Journal
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• v.27 no.1
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• pp.68-77
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• 2011

Fifty five species of medicinal plant materials were tested for their antifungal activity in vitro against Rhizoctonia solani AG 2-1 and Trichoderma harzianum to select plant species that can be used to improve the biocontrol efficacy of T. harzianum. Six species were effective against R. solani AG 2-1 but were also antagonistic to T. harzianum, except for Cinnamomum loureirii stem bark (CSB). CSB inhibited mycelial growth of R. solani AG 2-1 by 73.7% but showed an inhibitory effect on mycelial growth of T. harzianum by only 2.2%. Scanning electron microscophs showed that the CSB treatment resulted in deformed R. solani AG 2-1 hyphal cells, and transmission electron microscophs revealed degenerated cell structures such as degenerated cytoplasm and disentangled cell wall and the accumulation of electron-dense inclusions (asterisks) in the CSB treatment. The biocontrol efficacy of radish damping-off increased greatly following the combined treatments of T. harzianum and CSB and the combined treatment increased efficacy from 6.4-23.1% to 37.1-87.3% compared with either treatment alone. CSB did not affect T. harzianum population growth, as it was almost the same in rice-bran peat medium (culture) amended with 0.1% and 1.0% CSB powder as in non-amended medium. The formulation of T. harzianum in rice-bran peat medium amended with CSB powder reduced the severity of radish damping-off by 80.6%, suggesting that T. harzianum and CSB can be formulated as a biocontrol product for the control of R. solani AG 2-1.

• Journal of Plant Biology
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• v.27 no.1
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• pp.15-24
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• 1984

Leaf venation of 12 species of Lauraceae in Korea, native or introduced, was investigated and described by the use of Soft X-Ray. They could be grouped by the venation types, such as, 1. Actinodromous; Lindera obtusiloba, 2. Acrodromous; Cinnamomum camphora, C. japonicum, C. loureirii, 3. Brochidodromous having strongly developed basal secondary vein; Neolitsea aciculata, N. sericea, 4. Brochidodromous hoving irregulary branched secondary vein; Lindera erythrocarpa, L. glauca, 5. Brochidodromous having weak marginal loop; Machilus thunbergii, M.Japonica, 6. Brochidodromous having typical venation; Iozoste lancifolia, Litsea japonicum. This grouping corresponded with current classifying system at genus level except for genus Lindera, and supported Nakai's system at Tribe level. They also showed a gradual transition from brochidodromous to actinodromous types, but to certify the systematic value of this transition warrented more study. Identifying key for the species could be made by the venation type.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.393.1-393.1
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• 2002

Present study was performed for development of a new supplementary product with gastroprotective effect. Natural Products mentioned that have GI protective property on Dongeuibogam were evaluated anti-bacterial activity against Helicobacter pylori. then five herbs were selected. The material used for the test were water extract of Alpima oxyphylla (AO). Astragalus membranaceus (AM). Cinnamomum loureirii(CL). Citrus aurantium (CA), Amomum villosum (AV). (omitted)

• Korean Journal of Pharmacognosy
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• v.33 no.4 s.131
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• pp.389-394
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• 2002

Present study was carried out for development of a new supplementary product with gastroprotective effect. Natural Products mentioned that have GI protective property in Dongeuibogam and reports were evaluated anti-bacterial activity against Helicobacter pylori, then five heres were selected. The material used for the test were water extract of Alpinia oxyphlla (AO), Astragalus membranaceus (AM), Cinnamomum loureirii(CL), Citrus aurantium(CA), Amomum villosum(AV). They were tested individually on HCI ethanol-induced gastric lesion in rats, AV CL, AO showed the most significant effectiveness, respectively. Then two mixture different in their content ratio (P020701-1,-2) and complex with P020701-1 (CP) were made, and tested on HCI·ethanol, indomethacin-induced gastric lesion, aspirin-ligature, Shay ulcer and gastric secretion. P020701-1, -2 and CP showed significant effect on HCI ethanol, indomethacin-induced gastric lesion, and Shay ulcer. It can be regarded that the antigasuitic and anti-ulcerative effects of P020701- 1, -2 and CP are originated from reduction of total acid output identified by gastric secretion test.

• The Plant Pathology Journal
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• v.26 no.3
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• pp.253-259
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• 2010

In vitro and in vivo mycofumigation effects of the volatileproducing fungus Nodulisporium sp. CF016 isolated from stem of Cinnamomum loureirii and the role of its volatile compounds were investigated against phytopathogenic fungi. The volatile compounds produced by Nodulisporium sp. CF016 inhibited and killed a wide range of plant and storage pathogens including to Pythium ultimum, Rhizoctonia solani, Fusarium oxysporum, Phytophthora capsici, Sclerotinia sclerotiorum, Colletotrichum coccodes, Magnaporthe oryzae, Alternaria panax, Botrytis cinerea and Penicillium expansum. Mycofumigation with wheat bran-rice hull cultures of Nodulisporium sp. CF016 showed in vivo antifungal activity against gray mold caused by B. cinerea and blue mold caused by P. expansum of apple. The most abundant volatile compound produced by Nodulisporium sp. CF016 was $\beta$-elemene followed by 1-methyl-1,4-cyclohexadiene, $\beta$-selinene and $\alpha$-selinene. Nodulisporium sp. CF016 could be an attractive mycofumigant in controlling postharvest diseases of various fruits including apple.

• Journal of Korean Medical classics
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• v.24 no.4
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• pp.55-67
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• 2011

Through analyzing the frequencies of medicinal herb combinations in the prescriptions of "Bangyakhappyeon(方藥合編)", we could understand the characteristics of prescription composition and author's medical thoughts. So we conducted this study that analyze combination of 324 medicinal herbs in 467 prescriptions, and found meaningful combinations of 5,045. Among these, the most meaningful combination is the one of 10 herbs, Glycyrrhiza uralensis Fischer, Angelica gigas Nakai, Ziziphus jujube Mille, Atractylodes japonica Koidzumi, Poria cocas Wolf, Zingiber officinale, Rehmanniae radix preparata, Cinnamomum loureirii, Panax ginseng C.A.Meyer, Astragalus membranaceus. This combination is Sibjeondaebo-tang(Shiquandabu-tang) without Cnidium officinale and Paeonia japonica which compose Samul-tang(Siwu-tang). It means this combination is kind of modified Sibjeondaebo-tang(Shiquandabu-tang), which is more effective in tonifying qi than tonifying blood. Prescriptions of "Bangyakhappyeon(方藥合編)" involve herbs mostly used to improve weak and frail health and the herbs which are more effective in tonifying qi than tonifying blood. Through this study, we know the author' s one of medical view points on tonifying qi and blood, attaching importance to tonifying qi relatively to tonifying blood.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.2
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• pp.186-192
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• 2010

Skin wrinkles typically appear as a result of aging processes. One of causes may be the nonenzymatic glycation followed formation of browning products called advanced glycation endproducts (AGEs), an irreversible cross-linked protein. The accumulation of glycated collagen cross-linked in skin inhibits the formation and function of skin tightening agents such as collagen and elastin. To development for anti-wrinkle ingredients from edible plants, MeOH and hot-water extracts were prepared and evaluated for their inhibitory effects of AGEs formation. The activities of both extracts from bay laurel (Laurus nobilis), cinnamon (Cinnamomum loureirii), clove (Eugenia caryophyllate), oregano (Origanum vulgare), rosemary (Rosemarinus officinalis), savory (Satureja hortensis) and star anis (Illicium verum) of western spices, and blackberry (Rubus coreanus), dayflower (Commelina communis), Epimedium koreamun (whole), termunalia frutus (Terminalia chebula) and turkestan rose (Rosa rugosa) of medicinal plants were higher than the others. Of Korean vegetables, however, MeOH and hot-water extract from only Asters caber and green tea showed higher activities, and no activity in Korean marine plants (seaweeds).

• The Korean Journal of Pesticide Science
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• v.7 no.2
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• pp.83-91
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• 2003

Methanol extracts from 207 samples of 118 plant species in 44 families were tested for their fungicidal activities against six phytopathogenic fungi. Extracts of Thuja orientalis leaf, Cinnamomum loureirii leaf, Lindera erythrocarpa barks and leaf, Pinus koraiensis wood, Hovenia dulcis wood, Koelreuteria paniculata barks, Styrax japonica wood, Camelia japonica leaf and Cleyera japonica leaf showed very strong fungicidal activity against more than two phytopathogenic fungi at a concentration of 2000 ppm. As a naturally occurring fungicide, these plants could be useful as new fungicidal products against various plant diseases induced by plant pathogens.