• 한국연초학회지
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• 제30권1호
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• pp.14-24
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• 2008

The objective of this study was to determine the effect of smoking conditions on the in vitro toxicological activity of mainstream smoke. The 2R4F reference cigarette was machine-smoked by International Organization for Standardization(ISO) and Canadian Intense(CI) conditions. Smoke was analysed for chemical composition and in vitro toxicity. The cytotoxic potencies of both the total particulate matter(TPM), which were collected in Cambridge filter pad, and gas/vapor phase(GVP), which was bubbled through in phosphate-buffer saline in a gas-washing bottle, were assessed neutral red up take assay with chinese hamster ovary(CHO) cells. The assessment for genotoxicity of TPMs generated under ISO and CI conditions was determined using Salmonella mutagenicity assay and in vitro micronucleus assay. When calculated on an equal TPM basis, in vitro toxicity of TPM obtained under CI condition was decreased compared to TPM generated under ISO condition. The results of chemical composition analyses revealed that the lower toxicological activity under CI condition than that of ISO condition could be explained by the decreased in the contents of phenols, N-nitrosoamines and aromatic amines of TPM on an equal TPM basis.

• 한국식품영양과학회지
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• 제25권6호
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• pp.1050-1054
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• 1996

뇌졸중은 한국인에 있어서 발병율이 높은 성인병이며 또한 음주, 흡연과 관련이 있는 질병으로 알려져 있는바, 건강한 구성원만을 가진 정상인군과 뇌졸중 환자가 있는 가족의 구성원을 대상으로(환자 자신은 제외) 음주, 흡연정도, 수입과 가족병력을 조사하여 상관관계를 규명하고자 하였다. 뇌졸중 환자 가족의 평균 음주량이 정상인 가족 보다 높게 나타났는데 이는 가족 구성원 중 30대, 40대, 50대 남자의 음주량이 높은 것에 기인하는 것으로 나타났다. 뇌졸중 환자 가족의 흡연량이 정상인 보다 높았는데 이는 주로 뇌졸중 환자 가족중 40대와 50대 남자의 높은 흡연량에 기인하는 것으로 나타났다. 가구당 월 평균 수입은 정상인 세대가 뇌졸중 환자 가족에 비해 유의적으로 높았다(정상인 가족: $673,000\pm187,000원,$ 뇌졸중 환자 가족: $483,000\pm213,000원)$ 뇌졸중 환자가족에서 역시 뇌졸중 병력이 많은 것은 유전적 소인과 더불어 음주, 흡연과 상당한 관련이 있을 것으로 사료된다.

• 한국보건간호학회지
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• 제21권2호
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• pp.217-229
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• 2007

Purpose: This study sought to investigate the relationship between smoking, drinking and the mental health of adolescents. Method: The study subjects included 1,092 randomly sampled third-year middle and high school students from N-City and the L-Kun area in Chonbuk Province. The data were collected using an anonymous questionnaire developed by the Ministry of Health and Welfare(2005). The data were analyzed using the SPSSWIN 15.0 Program. Result: The smoking rate in the adolescents was 10.1%, and the drinking rate was 43.2%. The stress recognition rate in normal daily life was 45.5%, the frequency of depressive symptoms was 33.2% and 40.0% of the subjects reported that they wanted to die at some point within the past year. The rate of stress recognition, depressive symptom experience, suicidal planning and attempt in smokers and drinkers was higher than that in non-smokers and non-drinkers (p<.05). Especially, the frequency of suicidal thoughts was higher in the drinkers than in the non-drinkers (p<.05). Conclusion: The smoking and drinking status of the adolescents was correlated with their mental health a sit relates to stress, depression and suicide. Therefore, an effective program for the prohibition of cigarette smoking and alcohol consumption is needed in order to prevent smoking and alcohol consumption in adolescents and improve their mental health status.

• Journal of Nutrition and Health
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• 제27권3호
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• pp.253-262
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• 1994

This study was intended to investigate the anticarcinogenic effect of ginseng previously elucidated by other researches in animal studies. The sister chromatid exchange(SCE) method of human lymphocytes was used as a biomarker. Based on the literature search and the results of our laboratory, smoking was used as a parameter elevating the SCE frequency of general human population. To evaluate the smoking and ginseng effect on SCE frequency, 98 male healthy factory workers aged 23 to 58 years were divided into 4 groups : smoker with ginseng (SG), smoker control(SC), non-smoker with ginseng(NSG), and non-smoker control(NSC) groups, according to their smoking habits and ginseng intake. The mean sponteneous SCE per cell for the SG(10.8$\pm$0.3) and SC(10.4$\pm$0.3) groups were significantly higher than the NSG(9.1$\pm$0.2) and NSC(9.3$\pm$0.3) groups(p<0.05). High frequency cells (HFCs, cells with 15 SCEs) in SG and SC groups were also greater than those in NSG and NSC groups. However, the SCE levels of the SG and SC groups were not associated with the personal smoking history and the number of cigaretts smoked per day. Ginseng intake did not show any effect on the increased SCE caused by smoking. There were no correlations of the elevated SCE among smoking and ginseng types, history of ginseng intake, and consumption frequencies of ginseng intake. These results does not support the findings of other researchers that ginseng could be a protective agent to DNA damage.

• 한국융합학회논문지
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• 제12권9호
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• pp.331-341
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• 2021

본 연구는 우리나라 청·장년층 전자담배흡연자의 주관적 건강상태와 주관적 건강상태에 영향을 미치는 요인을 알아보기 위한 서술적 조사연구이다. 2019년 지역사회건강조사 원시자료를 활용하였으며, 성인 19-50세의 전자담배흡연 청·장년층 지역주민에 포함되는 2,607명의 자료를 최종분석에 사용하였다. 자료는 SPSS/WIN/26.0 프로그램의 복합표본분석 모듈을 이용하여, 기술통계, χ² test, 로지스틱 회귀분석을 통해 분석하였다. 연구 결과, 청·장년층 전자담배 흡연자의 주관적 건강상태 양호군은 90.2%, 주관적 건강상태 불량군은 9.8%로 나타났으며, 전자담배흡연자의 주관적 건강상태에 영향을 미치는 요인으로 Model I에서는 성별(p=.006), 연령(p=.036), 소득수준(p=.044), Model II에서는 신체활동(p=.033), 스트레스(p<.001)로 나타났다. 즉, 청·장년층 전자담배 흡연자에게 전자담배 흡연의 유해성에 대한 정확한 정보제공으로 자신의 주관적 건강상태에 대한 올바른 인식개선이 필요하며, 이들의 금연을 돕기 위한 운동 및 스트레스 관리 등의 맞춤형 건강관리 간호중재가 필요할 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7725-7730
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• 2013

Objective: The purpose of this study was to evaluate secondhand smoke (SHS) exposure inside selected public places to provide basic data for the development and promotion of smoke-free policies. Methods: Between March and May 2009, an SHS exposure survey was conducted. $PM_{2.5}$ levels and air nicotine concentrations were measured in hospitals (n=5), government buildings (4), restaurants (10) and entertainment venues (10) in Seoul, Republic of Korea, using a common protocol. Field researchers completed an observational questionnaire to document evidence of active smoking (the smell of cigarette smoke, presence of cigarette butts and witnessing people smoking) and administered a questionnaire regarding building characteristics and smoking policy. Results: Indoor $PM_{2.5}$ levels and air nicotine concentrations were relatively higher in monitoring sites where smoking is not prohibited by law. Entertainment venues had the highest values of $PM_{2.5}$(${\mu}g/m^3$) and air nicotine concentration(${\mu}g/m^3$), which were 7.6 and 67.9 fold higher than those of hospitals, respectively, where the values were the lowest. When evidence of active smoking was present, the mean $PM_{2.5}$ level was 104.9 ${\mu}g/m^3$, i.e., more than 4-fold the level determined by the World Health Organization for 24-hr exposure (25 ${\mu}g/m^3$). Mean indoor air nicotine concentration at monitoring sites with evidence of active smoking was 59-fold higher than at sites without this evidence (2.94 ${\mu}g/m^3$ vs. 0.05 ${\mu}g/m^3$). The results were similar at all specific monitoring sites except restaurants, where mean indoor $PM_{2.5}$ levels did not differ at sites with and without active smoking evidence and indoor air nicotine concentrations were higher in sites without evidence of smoking. Conclusion: Nicotine was detected in most of our monitoring sites, including those where smoking is prohibited by law, such as hospitals, demonstrating that enforcement and compliance with current smoke-free policies in Korea is not adequate to protect against SHS exposure.

• 생물치료정신의학
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• 제24권3호
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• pp.230-238
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• 2018

Objectives : Among adolescents, the proportion of daily smoking tends to increase with age, and does not return to the previous level. Therefore, we examined the factors associated with smoking frequency in a nationwide sample of Korean adolescents to help prevent the progression of smoking. Methods : Among 127,804 adolescents who participated in the 2016 and 2017 Korean Youth Risk Behavior Web-Based Survey, data from 7,781 adolescents who replied that they currently smoked were analyzed. According to the frequency of cigarette smoking, participants were classified into daily and non-daily smokers. Participants' socio-demographic characteristics, smoking behavior, and psychological problems including perceived stress, depressive mood, and suicidality were assessed. Results : There were 3,627(47.4%) daily smokers and 4,154(52.6%) non-daily smokers. Low parental educational level, and early smoking experience were positively associated with daily smoking. High academic achievement, and high socio-economic status were negatively associated with daily smoking. Daily smoking was positively associated with lower happiness, lower sleep satisfaction, and severe stress during the past 12 months. Factors affecting suicide attempts of smokers were sex, residential type, socioeconomic status, and early smoking experience. Conclusion : The results indicated that socially disadvantaged families, and smoking experience with young age influenced daily smoking among Korean adolescents. Daily smoking was associated with psychological problems including lower happiness, lower sleep satisfaction, and severe stress. Early smoking experience influenced suicidal attempts among Korean adolescent smokers. Early intervention for smoking cessation in this high-risk group may contribute to prevention of these psychiatric complications of smoking.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2005년도 제57차 추계 학술대회 연제집
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• pp.342-342
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• 2005

• 보건교육건강증진학회지
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• 제13권2호
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• pp.35-53
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• 1996

The objective of the health promotion program was to strengthen the ability and willingness of individuals in the course of each stage of their lives to take action in support of their health and that of their families and communities in the home, the place of work and the school, and during recreation. The purpose of this study was to assess the need of school health promotion through health care behavior survey about diet, accident prevention, cigarette smoking experience, personal hygiene, visual impairment prevention, exercise, and environment protection. The subjects of this study were 914 students composed of Samrye, Bongdong, Samrye-Dong, Iseo, and Songkwang elementary school in Wanju area. The data were collected by questionaire corrected for the purpose of this study which had been developed by WHO, ‘Health behavior in school children’. These were carried out from March 20 to April 20, 1996. The data was analyzed by frequency, percentage, χ²-test with SPSS-PC+ program. The results were as follows. 1. Diet related behavior 1) Girl students eat less breakfast than male students. 2) Girl students eat less 3 times a day than male students. 3) The rate of eating nutritious medicine was high in order of 4th, 6th, and 5th graders. 4) Girl students drink less milk than male students. 5) The intake frequency of eating between meals was high in order of 6th, 5th, and 4th grader. 2. Cigarette smoking behavior 1) The rate of cigarette smoking rarely was high in 5th grader. 2) Male students smoke cigarette more than girl students. 3. Personal hygiene related behavior 1) The rate of washing hands after using toilet room was low in order of 4th, 5th, and 6th graders. 2) The rate of washing hands after using toilet room was low in male students. 3) The rate of washing hands when entering home from outdoor was low in male students. 4) The tooth brushing frequency before going to bed was low in male students. 5) The tooth brushing frequency was low in male students. 6) The rate of bathing was most low in 4th grader. 7) The rate of bathing was low in male students. 4. Visual impairment preventive behavior 1) The distance between eyes and book was near in order of 6th, 5th, and 4th graders. 5. Exercise 1) The exercise time in school was less in 4th grader. 2) The exercise time in school was less in girl students. 3) The exercise time out of school was less in 4th grader. 4) The exercise time out of school was less in girl students. 5) The self evaluation score about exercise ability was low in girl students. 6. Environment related behavior D The rate of collecting waste separately in school was most low in 4th grader.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제31권4호
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• pp.291-299
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• 2005

Objectives : It is well known that cigarette smoking is harzardous to the osseointegration of dental implant, due to the impaired wound healing accompanied by reduced alveolar bone density. The aim of this study is to evaluate the influence of cigarette smoke on the implant osseointegration by the time factor consideration. Materials and methods : Twenty-four male Spraque-Dawley rats (8 weeks, weighting 200 to 250g) were used in this study. In the experimental group, 13 rats were exposed to cigarette smoke, 8 minutes per day during 6 weeks, and 12 rats in the control group were not exposed at any time. RBM (Resorbed blasting media) surfaced implant (diameter 3.3mm, length 5.0mm, AVANA Co., Korea) was placed in the right femur of each rat. Each implant with surrounding bone was prepared with microtome (cutting band 0.2mm$^{(R)}$, EXAKT Co., Germany) after 1 day, 2, 4, 8 and 12 weeks and stained with toluidine blue (1%). Another clinical investigation of each implant was also done at each evaluation time. Results : Clinical investigation around implant fixture showed that there were no significant differences between the control and experimental group. Microscopic observation around implant fixture showed that there were significant differences between the control and experimental group at the initial stage after implant fixture installation. Experimental group showed a decreased bone to implant contact within 4 weeks compared to control group, but showed similar characteristics after 4 weeks. Conclusion : Smoking inhalation effect on the dental implant showed the impaired wound healing by vasoconstriction and decreased intramedullary blood flow at initial stage of osseointegration. This experimental results can be clinically useful to the implant surgery of smoking patients.