• The Journal of Pediatrics of Korean Medicine
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• v.18 no.2
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• pp.61-76
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• 2004

Objective : To demonstrate of regulatory effect of atopic allergic regulation by Chungsangbangpoong-Tang(CBT), This experiment was studied. Methods : The author investigated a possible effect of CBT on cytokines production using human T cell line (MOLT-4) or human mast cell line (HMC-1). In addition, the author investigated whether CBT has inhitory effects on compound 48/80- induced histamine release from rat peritoneal mast cells (RPMC) and compound 48/80-induced ear swelling in ICR mice. Results : CBT (0.01 mg/ml)-containing medium in stimulated culture supernatants significantly increased IL-2 secretion compared with untreated MOLT-4, whereas CBT (0.01-1.0 mg/ml)-containing medium in stimulated culture supernatants significantly decreased IL-4 secretion compared with untreated MOLT-4. Significant reduced levels of IL -6 and $TNF-{\alpha}$ were observed in the HMC-l with CBT (P<0.05). CBT did not inhibit the histamine release from the RPMC but inhibit ear swelling response. Conclusion : These results suggest that CBT contributes to the treatment of atopic allergic reactions, such as atopic dermatitis and that its action may be due to regulation of cytokine production.

• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.185-191
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• 2013

Purpose: This study aims to explain the effect of Chungsangbangpoong-Tang(as followed CBT) on an adulthoods' acne vulgaris. Methods: This is a case report on a female patient who has been suffering from acne vulgaris since she was 19 years old. To make her acne condition better, we designed to provide a specific combined treatment, mainly drinking CBT 2 or 3 times per a day with taking a herbal, acupuncture therapy and acupuncture once per every week through whole session. Results: After a series of we prescribed CBT treatments, we could find that CBT treatments are effective and available to ameliorate for her symptoms of acne vulgaris within its period. Conclusion: This clinical case study shows us that CBT might have not only a potentiality as a new acne treatment but also an effect as a new available prescription for adulthoods' acne. Hence more specific studies about CBT should be demanded in a treatment fields of adulthoods' acne vulgaris as soon as possible.