• 대한추나의학회지
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• 제2권1호
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• pp.143-157
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• 2001

Objectives and Methods : To evaluate the mechanism of oxidative damage by xanthine oxydase(XO) and hypoxanthine(HX)-induced oxygen radicals, MTT assay and NR assay were carried out after the cultured mouse spinal sensory neurons were preincubated for 4 hours with various concentrations of XO/HX. And the amount of total protein. neurofilament EIA. lipid peroxidation and LDH activity were measured, to evaluate the protective effect of Herbar Chelidonii(HC) water extract on cultured spinal sensory neurons damaged by XO/HX. after the cultured mouse spinal sensory neurons were preincubated with various concentrations of HC water extract for 3 hours prior to exposure of XO/HX. Results : XO/HX decreased significantly the survival rate of the cultured mouse sensory neurons by NR assay and MTT assay In proportion to concentration and exposed time. In proportion to concentration and exposed time on cultured spinal sensory neurons, XO/HX showed the quantitative decrease of neurofilament by EIA. the decrease of total protein amount by SRB assay and the Increase of lipid peroxidation as well as LDH. HC showed the quantitative increase of neurofilament and total protein, but showed the decrease of lipid peroxidation and LDH activity against the neurotoxicity of XO/HX. Conclusions : From the above results, it is concluded that XO/HX have a neurotoxic effect on cultured spinal sensory neurons and that the herbs extract, such as HC, prevent the toxicity of XO/HX effectively in that they decrease lipid peroxidation and LDH activity.

• 척추신경추나의학회지
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• 제7권2호
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• pp.63-74
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• 2012

Objectives : The purpose of this study was to evaluate the effect of Oriental medical treatment in patients with Spondylolisthesis and lumbar Herniated Intervertebral Disc(HIVD). Methods : This clinical study was carried out on 39 patients with Spondylolisthesis and lumbar Herniated Intervertebral Disc(HIVD), who had been admitted from Jan. 2012 to Nov. 2012. All of 39 patients were treated with acupuncture, Chuna treatment and herbal medicine during the whole admission period. Verbal numerical rating scale(VNRS) and Oswestry disability index(ODI) were used to evaluated the effectiveness of the Oriental medical treatment. Results : 1. Significant improvement of the symptoms of low back pain and leg pain on 39 patients with Spondylolisthesis and lumbar Herniated Intervertebral Disc(HIVD) was seen when evaluated with VNRS and ODI. 2. There was no significant difference of improvement by herniated type when evaluated with VNRS and ODI.. 3. There was no significant difference of improvement by spondylolisthesis type(degenerative and spondylolytic) when evaluated with VNRS and ODI. Conclusions : These results suggest that in the case of low back pain and lower limb numbness caused by Spondylolisthesis and HIVD, conservative treatments can be considered as one of the options of treating the symptoms beside surgical way.

• 대한추나의학회지
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• 제3권1호
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• pp.15-29
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• 2002

Objectives : This experimental study was designed to investigate the effects of Galgunseunggi-tang on the weight of obese rats Induced by high fat diet. Methods : A series of have been conducted in order to measure the effects of the above materials weight. serum and fat cells. The have been performed on; (1) the Increasing amount of body weight; (2) the quantity of total cholesterol, tryglyceride, total lipid, free fatty acid, phospholipid, HDL -cholesterol and LDL -cholesterol in serum; (3) the average size of epididymal fat cells and the area rate of fat drops in hepatic lobule. Results : The results were summarized as follows: 1. It was proved that Galgunseunggi-tang suppressed the increasing amount of body weight. GS II group (supplied 60mg per 100g) showed a significant value. 2. It was proved that Galgunseunggi-tang improved the total cholesterol, HDL -cholesterol In serum. but did not show a significance. 3. It was proved that Galgunseunggi-tang decreased the quantify of free fatty acid, phospholipid, LDL -cholesterol in serum. GS I group (supplied 30mg per 100g) showed a significant value. 4. It was proved that Galgunseunggi-tang decreased the quantity of triglyceride, total lipid in serum, and GS II group showed a significant value. 5. Galgunseunggi-tang decreased the average size of epididymal fat cells and the area rate of fat drops In hepatic lobule, and GS I group showed a significant value. Conclusions : Based on the above result, it is assumed that the clinical application of Galgunseunggi-tang can help the treatment of obesity.

• 대한추나의학회지
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• 제5권1호
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• pp.93-100
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• 2004

본 증례는 요각통 환자에게 다양한 한방치료를 시술하였으나 별무호전인 경우 M.T.S요법을 추가로 시행함으로써 양호한 결과를 보인 임상례이다. 요통환자가 장기간의 치료에도 차도가 없거나 호전에 미미했을 때 물론 의사의 마음에도 불가피하게 수술을 해야 될 것이라는 생각이 떠오르게 된다. 하지만 수술을 해야 할 것인지 혹은 하지 말아야 할 것인지 결정을 내리기 전에 충분히 다른 치료법을 시행해 볼 필요가 있다. 이에 저자는 장기간의 치료에도 차도가 없거나 호전이 미미한 요통 환자에게 M.S.T 요법을 시행할 경우 양호한 결과를 얻으리라 사료되어 보고하는 바이다.

• 척추신경추나의학회지
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• 제2권1호
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• pp.59-67
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• 2007

Objective : Poly neuropathy is disease that reveals musle relaxation or sensory disorder, and Myopathy is disease that reveals musle weakness, wasting, pain. These diseases occur in the lower or upper limbs. This is the clinical report about Poly neuropathy or Myopathy estimated patients. Method : Patients were treated by acupuncture, herb medicine, bee venom herbal-acupuncture, moxibustion. We evaluated the improvement of symptoms with ROM(Range of Motion) and MCR(Medical Research Council) standard. Result : Symptoms that patients have at admission improved and disappered gradually with oriental medicine therapy. Observing the change of ROM and MCR standard, they indicated us improvement of disease. Conclusion : We achived a desirable result from treatment of peripheral neuropathy or myopathy estimated patients. However, further studies are required to prove the effect of oriental medicine treatment.

• 대한추나의학회지
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• 제2권1호
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• pp.169-175
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• 2001

Objects : The purpose of this study is find out significant (clinical) effect of applying acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) of ${\bar{U}m-kyo-maek$(陰?脈) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) of Yang-kyo-maek(陽?脈) to a patient of circadian sleep disorder. Methods : We apply acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) to a patient of circadian sleep disorder during 2 weeks. We check sleeping time day and night during 14 days. Acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder patient. Results : Acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder patient. Conclusions : 1. The physio-pathologic phenomenon of sleeping is relative to ${\bar{U}m-kyo-maek$(陰?脈) and Yang-kyo-maek(陽?脈) 2. Acupuncture therapy on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder.

• 척추신경추나의학회지
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• 제2권2호
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• pp.105-116
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• 2007

Objectives : Physical activity is known as beneficial to mental health like decreasing depression and stress. In this study, we tried to find out the relationship between body composition, stress, depression, and self-esteem with physical activity level. Methods : International Physical Activity Questionnaire(IPAQ)-short form, SRRS(Social readjustment rating scale), SRI(Stress response index), and BDI(Beck's depression index), SES(Self-esteem scale) were given to peri-menopausal women aged 45-55 and BMI$\geq$23kg/m2. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results : The mean of physical activity of total subjects was 2406MET-min/week(n=42). The physical activity of overweight(23kg/m2$\leq$BMI<25kg/m2) and obese(BMI$\geq$25kg/m2) permimenopausal women was 1428MET-min/week and 2970MET-min/week(p<0.05) respectively. When three levels of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The scores of BDI, SRRS, and SRI were lower and that of SES were higher in HEPA active group, not showing statical significance. Anger(subscale of SRI) measures were lower and SES measures were higher in HEPA active group than others among overweight women(p<0.05). Conclusions : The level of physical activity of peri-menopausal women was on the average, but the vigorous activity is thought to be necessary. The HEPA active group showed lower depression, stress and higher self-esteem than minimally active and inactive group.

• 대한추나의학회지
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• 제1권1호
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• pp.91-102
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• 2000

To prove the effect of Yukmijihwngwon(YMJHW) and Taeyoungjeon(TYJ) extract on the Meridian of Human body and Active oxygen experimentally, ORS & Free Radical of extract and precipitate of YMJHW and TYJ was measured. The results were summarized as follows; 1. TYJ extract, as a result of measuring QRIS, had a considerable effect on the function of pituitary gland, the 4th cervical vertebra and the 1 st lumbar vertebra. 2. TYJ precipitate, as a result of measuring QRIS, had a considerable effect on the function of liver, uterus, and vertebra. 3. YMJHW extract, as a result of measuring QRIS, had a considerable effect on the function of lung, adrenalin gland, bladder, prostate gland, ovaria, the 2nd cervical vertebra, the 3rd cervical vertebra, the 5th cervical vertebra, the 6th cervical vertebra, the 2nd lumbar vertebra, the 4th lumbar vertebra and the 5th lumbar vertebra. 4. YMJHW precipitate, as a result of measuring QRIS, had a considerable effect on the function of spleen, lung, kidney, adrenal gland, bladder, ovaria, the 2nd cervical vertebra, the 6th cervical vertebra, the 7th cervical vertebra, the 2nd lumbar vertebra, the 5th lumbar vertebra, sacrum, and knee joint. 5. As a result of measuring Free Radical, the level of TYJ is higher than YMJHW. It is thiut that's because of Duchung and roasted Gamcho. 6. As an order of QRIS levels, YMJHW precipitate is the highest, YMJHW extract is next, TYJ extract and TYJ precipitate. These results suggested that TYJ and YMJHW be usefully applied for suppressing of abnormal Meridian and noxious oxygen, preventing and curing all the disease.

• 척추신경추나의학회지
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• 제1권1호
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• pp.1-14
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• 2006

Objectives : The causative pathology of acute muscular pain cannot be defined in many patients. To evaluate the relations between mental state and acute muscular pain patients, the author surveyed symptom check list-90-Revision(SCL-90-R) in patients with acute muscular pain. Materials and Methods : From November 2004 to June 2005, a questionnaire including SCL-90-R was given to patients(52 persons) who visited our department for acute(<7days)muscular pain of neck(22 persons) or low back(30 persons). Fifty two patients(30 male, 22 female) completed SCL-90-R Results : 1. Mean values of T-scores on all 9 basic scales in the patients groups were within normal range. but T-scores SOM in the patients groups were significantly very higher than those in Normal groups(p<0.01). 2. The T-scores of SOM In low back pain patients were significantly higher than those in Normal groups(p<0.05). 3. There was no significant difference in all scales between acute muscular pain and L-spine HIVD patients groups. 4. There was no significant difference in all scales between acute muscular pain and general back pain patients groups. 5. There was no significant difference in all scales between male and female in the patients groups. Conclusion : It is concerned between T-scores on all 9 bas κ scales of SCL-90-R and acute muscular pain. Especially acute muscular pain of back has a relation to somatization of T-scores on all 9 basic scales of SCL-90-R.

• 척추신경추나의학회지
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• 제15권1호
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• pp.1-33
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• 2020

연구 목적 : 본 연구는 근골격계 질환에 대한 수기치료가 갖는 경제적 효과를 체계적으로 평가해 보기 위해 시행되었다. 연구 방법 : 2017년 2월 2일까지 국내외 관련 문헌을 체계적으로 검색 하였으며, 연관된 체계적 고찰 논문의 참고문헌을 조사하였다. 두 명의 연구자가 독립적으로 문헌을 선택하고, 비뚤림 위험 평가 및 경제성 평가 질 평가, 자료 추출을 시행하였다. 연구 결과 : 총 3,327개의 논문을 검토하여 최종적으로 18개의 무작위 대조 연구가 포함되었다. 경제성 평가는 수기요법과 다른 치료방법간의 유효성 비교를 통해 시행되었다. 요부 통증, 견관절 통증 및 외측 상과염 치료에 있어 침치료, 견인치료, 주사치료, 일반의 치료, 척추 안정화 기법 및 통증관리 치료보다 비용 효과적인 것으로 나타났다. 또한 또한, 수기치료는 경항통, 흉통, 고관절염 혹은 슬관절염, 경추신경병증 및 수부손상 치료에 있어 일반적 치료, 물리치료, 자가 치료 프로그램, 견인 치료에 비하여 효과적인 치료인 것으로 확인되었다. 결론 : 18개의 논문 중 10개의 논문에서 근골격계 질환 치료에 있어 수기치료가 경제적으로 효과가 있는 것으로 나타났다. 이러한 결과는 다른 치료방법에 비해 수기요법이 근골격계 질환에 있어서 경제적 가치가 있음을 시사하는 내용이다. 하지만, 근골격계 질환 수기치료의 경제성 평가에 대한 선행 연구는 전반적으로 부족한 실정으로, 보다 정확한 결과를 제시하고 정책결정을 위한 효과적인 제안을 위해서는 체계적인 추가 연구가 필요하다 사료되는 바이다.