• 한방안이비인후피부과학회지
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• 제28권3호
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• pp.88-100
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• 2015

Objectives : This study was designed to assess the effect of Soyangin Medicines on Soyangin chronic urticaria patients by retrospective methods.Methods : We treated 37 Soyangin chronic urticaria patients who visited Haneulmaeum Korean Medicine Clinic from September 1st 2011 to June 30th 2014. We administrated the Soyangin patients with Soyangin Medicines such as Hyeongbangsabaek-san(荊防瀉白散), Yanggyeoksanwha-tang(凉膈散火湯) and so on for 3 months. We measured the effect biweekly by using Urticaria Activity Score(UAS). We analyzed the information and medical history of patients by Frequency analysis, and UAS by Repeated measures, ANOVA.Results & Conclusions : Every items of UAS were improved by Soyangin Medicines. And the improvement was statistically significant(p<0.05).

• 한방안이비인후피부과학회지
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• 제29권1호
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• pp.168-173
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• 2016

Objective : The purpose of this study is to investigate the recurrence rate of Chronic Idiopathic Urticaria patients treated with Pyungweesangamibang through long-term follow-up survey.Methods : This tracing study was conducted for sixty-seven Chronic Idiopathic Urticaria patients who received and have finished treatment with Pyungweesangamibang at Woobo Korean Medicine Clinic in 2013 and 2014.Result : 81.4% of the patients, who had spent over 1 year since the finish of treatment with Pyungweesangamibang, did not relapse. In case of more than 2 years elapse, 66.7% of the patients did not suffer relapse.Conclusion : The result of tracing recurrence of the Chronic Idiopathic Urticaria patients treated with Pyungweesangamibang describes that the Korean medical treatment (Pyungweesangamibang prescription) shows lower recurrence rate than other general treatment shows.

• 한방안이비인후피부과학회지
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• 제10권1호
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• pp.357-366
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• 1997

Urticaria is an erythematous or white non-pitting edematous plague that changes in size and shape by peripheral extention or regression during the few hours or days. Urticaria is classified as acute or chronic type. The etiology of acute urticaria has been determined in many case, but the cause of chronic urticaria has been determined in only $5\%\;to\;20\%$ of cases. This observation was aimed to evaluate the clinical manifestations and clinical indence of urticaria seen between June, 1995 and November, 1996(18months) at the Department of Dermatology, Oriental Medical Hospital, Kyung Hee University. The results were summarized as follows ; 1. In the cases of 106 patients, $43\%\;were\;male\;and\;51\%$ were female. 2. The pick incidence of age group was 20 to 29($32\%$). 3. The most frequent duration of urticaria was from 2 months to 6 months. 4. In this study, the inciting causes could not be found in $61\%\;of\;acute\;patients,\;60\%$ of chronic patients. 5. Among 107 patients, $5\%$ of all patients had personal history of atopic diseases and $9\%$ of all patients had familly history. 6. Angioedema was founded in 7 patients, and the most common involved site were lips, eyelids and tongue. 7. The most frequently treated prescription was Chhunggisan which occupied $51\%$ of all, Gyakhangjunggisan(41\%$) and Gosamhomasan($25\%$), Bangpoongtongsungsan($22\%$) in that order of frequency.

• 한방안이비인후피부과학회지
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• 제35권4호
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• pp.200-208
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• 2022

만성 두드러기 환자에게 조위승기탕(調胃承氣湯) 가감방(加減方) 투여가 증상 호전에 효과를 나타냄을 확인할 수 있었다. 본 환자는 변비 및 상열감과 함께 구진성 두드러기와 중증도 이상의 소양감을 호소하였고, 항히스타민제와 외용 양약 제제에 반응하지 않았지만 한약 복용 후 피부 소양감 및 병변의 개선을 보였다. 조위승기탕(調胃承氣湯)의 완하(緩下)작용이 적열(積熱)을 풀어 피부 질환에 유효한 효과를 갖는 것으로 보이고, 이로써 만성 두드러기에서 치료 효과를 발휘한 것으로 사료된다.

• 한방안이비인후피부과학회지
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• 제26권4호
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• pp.60-69
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• 2013

Objective : This case series study was designed to assess the effect of Gamisungmagalguntang for chronic urticaria identified as "Wind-Heat" pattern by retrospective methods. Methods : We treated 19 patients for chronic urticaria with Gamisungmagalguntang(加味升麻葛根湯), who visited to care chronic urticaria at the department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine at Kyunghee University Korean Medical Center from 1st January 2013 to 31st August 2013. We analyzed information and body conditions of 19 patients. And by using Urticaria Activicy Score(UAS), frequency and number of wheals, itch severity and total score on a 4-point(0-3) scale were assessed in 19 patients. The change of each criterion and total scores between baseline and follow up were analyzed using paired t-test and Wilcoxon test(p<0.05). Results : 1. UAS improvement was statistically significant(p<0.001). Effects of symptom improvement were excellent(31.58%) that means symptom remission and good(42.10%) that means symptom improved over 50%. 2. Heat sensitivity as suspected provocation factor could be a marker for the Wind-Heat pattern urticaria. 3. Among the Wind-Heat pattern urticaria patients, normal digestion(52.63%) and no thirst(78.95%) were higher than abnormal conditions. Whereas about sweat item, abnormal conditions(57.89%) were higher than normal. That means abnormal sweat conditions could be a marker for a defense qi(衛氣) dysfunction of the Wind-Heat pattern urticaria. Conclusions : Our findings suggest that Gamisungmagalguntang could be effective on the Wind-Heat pattern urticaria.

• 사상체질의학회지
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• 제34권2호
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• pp.84-96
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• 2022

Introduction Chronic idiopathic urticaria in patients diagnosed with an unfavorable pattern in Soyangin and Taeumin based on Sasang medicine showed a significant improvement after herbal medicine treatment. Methods The patients had treatment with both herbal medication and antihistamine. We checked the patients' cutaneous manifestation, original symptoms, and the number of antihistamine doses in each visit. We evaluated the medical records retrospectively. Results After one month of treatment, the patients showed cutaneous manifestation relief. Each patient reduced and withdrew antihistamine at four moths and eight months respectively, and the cutaneous manifestation did not recur. We maintained the herbal medicine prescription until the origin symptoms improved. Throughout the subsequent follow-up, the patients showed both urticaria and the original symptoms in good condition without treatment. Discussion Sasang medicine treatment can be an effective treatment for chronic idiopathic urticaria and long-term management is necessary for an unfavorable pattern which can take more than 6 months.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.189-198
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• 2016

Objectives : The purpose of this study is to report 1 clinical experience of korean medicine treatment on chronic urticaria identified as "Wind Heat" pattern. Methods : We treated a 63-year old woman patient with Gagamtongcheong-san, acupuncture and pharmacopuncture. The improvement of patients evaluated using CU-Q2oL, UAS, and photography. Results : CU-Q2oL score decreased from 95 to 18, UAS decreased from 6 to 0. Conclusions : The complex treatments of korean medicine and was effective to improve of chronic urticaria. It is necessary to have more observations and case reports.

• 한방안이비인후피부과학회지
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• 제17권2호
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• pp.81-86
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• 2004

Objective: This study was designed to investigate clinical features of chronic urticaria and assess Korean traditional medical therapy on that. Methods: The ratio of male and female, duration of symptoms, personal history and family history of allergic diseases, serum IgE level, and suspected causes and provocation factors were investigated in 41 patients with chronic urticaria. And frequency of wheals, duration of wheals, number of wheals, itch severity, and antihistamine counts of 6-point(0-5) score was assessed in 26 patients. The change of total scores between baseline and follow up were analyzed using Wilcoxon signed-rank test(p〈0.05). Results: 1. The ratio of male and female was 1:1.28 and the mean duration of symptoms was 26.0 months. 2. The frequency of personal history and family history of allergic diseases was each 53.7$\%$ and 48.8$\%$ and 30.6$\%$ had over 200 IU／mL serum IgE level. 3. The suspected causes were none(43.9$\%$), foods(29.3$\%$), drugs(9.8$\%$) and stress(7.3$\%$). 4. The suspected provocation factors were foods(39.0$\%$), none(19.5$\%$), fatigue(17.0$\%$), heat and sweating(l4.6$\%$), pressure(12.2$\%$) and stress(9.8). 5. The total scores between baseline and follow up of 26 patients was lowered from 14.85${\pm}$3.80 to 7.65${\pm}$4.31 and it was significant statistically. Conclusions: Korean traditional medical therapy was proved to be effective on the chronic urticaria and we need to consider foods as important factor in both treatment and patient education of urticaria.

• Clinical and Experimental Pediatrics
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• 제52권2호
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• pp.205-212
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• 2009

목 적 : 만성 두드러기는 적어도 6주 이상 팽진이 지속되는 것으로 정의되며, 그 원인을 모르는 경우가 대부분이다. 본 연구에서는 소아에서의 만성 두드러기의 원인과 임상경과를 알아보고자 하였다. 방 법 : 최근 4년간 순천향대학교 부천 병원에서 치료받았던 만성 두드러기 환아 51명을 대상으로 의무기록 분석과 전화 추적을 통해 검사결과와 임상양상 및 경과를 조사하였다. 결 과 : 내원 시 연령은 중앙 나이가 4년(8개월-16세)이었고, 남아가 30명, 여아가 21명으로 남녀 비는 1.4:1이었다. 원인으로서는 원인이 밝혀지지 않은 경우가 38명(74.5%)으로 가장 많았으며, 물리적 두드러기가 10명(19.6%), 식품 첨가물이 원인인 경우가 3명(5.9%)이었다. 피부 묘기증이 22명(42.3%), 혈관부종이 6명(11.5%)에서 동반되었다. 검사실 소견상 33명 중 18명(54.5%)에서 H. pylori IgG 항체가 양성이었고, 이중 5명이 이에 대한 치료를 받았으며 모두 치료 후 호전을 보였으나 3명은 수개월 후 두드러기가 재발하였다. 36명 중 9명(25.0%)은 ANA가 양성이었다. 갑상선 자가 항체를 포함한 갑상선 검사는 모두 정상이었다. 식품 첨가물 유발 검사에서 양성을 보인 환아가 3명(글루타민산염 2명, 글루타민산염 & 아황산염 1명) 있었다. 내원 전 두드러기 지속기간은 평균 17주(6-40주)였다. 치료 후 6개월까지의 추적 관찰에서 51명 중 36명(70.6%)의 환아가 완해를 보였다. 내원 후 1년까지 46명 중 39명(84.8%)이 완해를 보였으며, 이들의 내원 후 완해까지의 기간은 평균 11주(1주-1년)였으며 총 지속기간은 24주(6주-2년)였다. 1년 이상 지속된 환아는 7명으로, 두드러기의 총 지속기간은 평균 1년 10개월(13개월 2주-3년 9개월) 이었다. 결 론 : 소아 만성 두드러기의 원인으로서는 특발성이 대부분이었고, 밝혀진 원인으로는 물리적 두드러기가 가장 많았다. 대부분에서 내원 1년 이내에 두드러기가 소실되어 소아 만성 두드러기의 예후는 양호함을 알 수 있었다. 본 대상 환자에서 H. pylori 항체 양성률과 ANA 양성률이 높게 나타나, 이들과 소아 만성 두드러기와의 관계를 규명하기 위해서는 이에 대한 추가적인 연구가 필요할 것으로 생각된다.

• 한방안이비인후피부과학회지
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• 제22권3호
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• pp.196-207
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• 2009

Objectives : This study was designed to investigate the chronical features of urticaria and the effects of urticaria treatment with Ko-Bang(古方). Methods : We treated 39 patients for urticaria with Ko-Bang(古方), who visited to care urticaria at the Dept. of Dermatology Oriental medical hospital Dong-eui university from Jan, 2008 to Sep, 2009. This study was assessed using the chart analysis and the follow-up survey by telephone. Results & Conclusions : 1. 39 outpatients were surveyed, who were 20 males and 19 females. And patients who were ages 21-30 were the largest group, 11(28.21%). Among the 39 patients, acute urticaria patients were 8(20.5%), chronic urticaria patients were 31(79.5%), and contraction of a disease period between 6 weeks with 3 months was 17.9%. 2. The causes of urticaria were measured unknown 37.5%, foods 37.5%, drugs 25% in acute and unknown 35.5%, a change of temperature 29%, foods 16% in chronic. And suspected provocation factors were measured unknown and foods each 12 cases. The most of accompanied symptoms was itching sign(34 cases), the second most was self-conscious fever(10 cases). 3. Out of treat prescription(Ko-Bang,古方), Injinho-Tang(茵蔯蒿湯) was used most in 5 cases, Daehwanghwangryunsasim-Tang(大黃黃連瀉心湯), Hwangryun-Tang(黃連湯), Daesiho-Tang(大柴胡湯) were used in each 4 cases, Galgeun-Tang(葛根湯), Chijadaehwangsi-Tang(梔子大黃豉湯), Sosiho-Tang(小柴胡湯) were used in each 3 cases, Gaemagakban-Tang(桂麻各半湯), Chijasi-Tang(梔子豉湯),Oryeongsan(五笭散) were used in each 2 cases. 4. When the processes of treatment were classified by one poison(一毒), there were the 19 cases (48.7%) which was caused by Bun(煩), the 12 cases(30.8%) by Water(水) and the 4 cases(10.3%) by Gyur(結).