• Title/Summary/Keyword: Chromosome 10

Search Result 1,321, Processing Time 0.026 seconds

Development of Semi-Automatic Karyotyping System Using Image Processing (화상처리를 이용한 반자동 핵형분석 시스템의 개발)

  • 김학경;강병철;박준형;서진호;김상봉
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.9 no.10
    • /
    • pp.844-851
    • /
    • 2003
  • We introduces a development result of semi-automatic karyotyping system using image processing method to improve a long time working of the manual method and 5% error of traditional automatic karyotying system for analyzing karyotying. The karyotyping procedures have many routine tasks such as searching metaphases, taking pictures, developing, editing, etc. There are several automatic karyotyping systems in order to reduce the task in advanced countries. However, they are very expensive, applicable to only human chromosome, and have too many functions to use easily. This paper takes aim at high quality image resolution and development of interface that can adjust brightness and contrast of image on-line. The system can be applied to animal and plants as well as human's chromosome. The system developed in this paper is applied to pig and human. The effectiveness of the system is proved by hospitals in Korea.

Anesthetic management of a patient with chromosome 6p duplication: a case report

  • Morinaga, Saori;Tsukamoto, Masanori;Yokoyama, Takeshi
    • Journal of Dental Anesthesia and Pain Medicine
    • /
    • v.17 no.2
    • /
    • pp.139-141
    • /
    • 2017
  • Chromosome 6p duplication is very rare and clinically characterized by short stature, mental retardation, and congenital heart diseases. Patients with mental retardation may present with poor oral health conditions. Dental treatment may need to be performed under general anesthesia in such patients. Our case report deals with induction of general anesthesia to a patient with chromosome 6p duplication, for dental treatment. The selection of a nasotracheal tube of an appropriate size, because of the patient's short stature, was especially important for airway management. In the present case, the patient with chromosome 6p duplication was intubated with a nasotracheal tube, which was not age-matched but adapted to the height and physique of the patient.

Simultaneous Overexpression of Integrated Genes by Copy Number Amplification of a Mini-Yeast Artificial Chromosome

  • Jung, Heo-Myung;Kim, Yeon-Hee
    • Journal of Microbiology and Biotechnology
    • /
    • v.28 no.5
    • /
    • pp.821-825
    • /
    • 2018
  • A copy number amplification system for yeast artificial chromosomes (YACs) was combined with simultaneous overexpression of genes integrated into a YAC. The chromosome VII (1,105 kb) was successfully split to 887 kb, 44 kb containing the element for copy number amplification, and a 184-kb split-YAC. The 44-kb split-mini YAC was amplified a maximum of 9-fold, and the activity of the reporter enzymes integrated into the split-mini YAC increased about 5-7-fold. These results demonstrate that the mini-YAC containing a targeted chromosome region can be readily amplified, and the specific genes in the mini-YAC could be overexpressed by increasing the copy number.

Cooperative Behavior of Distributed Autonomous Robotic Systems Based on Schema Co-Evolutionary Algorithm

  • Sim, Kwee-Bo
    • International Journal of Fuzzy Logic and Intelligent Systems
    • /
    • v.2 no.3
    • /
    • pp.185-190
    • /
    • 2002
  • In distributed autonomous robotic systems (DARS), each robot must behave by itself according to its states ad environments, and if necessary, must cooperate with other robots in order to carry out their given tasks. Its most significant merit is that they determine their behavior independently, and cooperate with other robots in order to perform the given tasks. Especially, in DARS, it is essential for each robot to have evolution ability in order to increase the performance of system. In this paper, a schema co-evolutionary algorithm is proposed for the evolution of collective autonomous mobile robots. Each robot exchanges the information, chromosome used in this algorithm, through communication with other robots. Each robot diffuses its chromosome to two or more robots, receives other robot's chromosome and creates new species. Therefore if one robot receives another robot's chromosome, the robot creates new chromosome. We verify the effectiveness of the proposed algorithm by applying it to cooperative search problem.

Chromosome number of myoga ginger (Zingiber mioga: Zingiberaceae) in Korea

  • IKEDA, Hiroshi;NAM, Bo-Mi;YAMAMOTO, Nobuko;FUNAKOSHI, Hidenobu;TAKANO, Atsuko;IM, Hyoung-Tak
    • Korean Journal of Plant Taxonomy
    • /
    • v.51 no.1
    • /
    • pp.100-102
    • /
    • 2021
  • The chromosome number of myoga ginger (Zingiber mioga (Thunb.) Roscoe: Zingiberaceae) has been reported as 2n = 22 for Chinese plants and 2n = 55 for Japanese plants. We checked the chromosome number of Z. mioga in plants collected in Jeollabuk-do and Jeollanam-do, Korea, and counted 2n = 44, the first report of this number for the species. As the basic chromosome number of Z. mioga is thought to be x = 11, Z. mioga plants in China, Korea, and Japan appear to be diploids, tetraploids, and pentaploids, respectively. In finding the tetraploid race of Z. mioga in Korea, we can hypothesize that the pentaploid race in Japan is derived through the fertilization of reduced gametes of the diploid race and unreduced gametes of the tetraploid race.

Chromosome number of Carex brevispicula (Cyperaceae), a sedge endemic to Korea

  • Kyong-Sook CHUNG;Gi Heum NAM;Gyu Young CHUNG
    • Korean Journal of Plant Taxonomy
    • /
    • v.53 no.2
    • /
    • pp.166-169
    • /
    • 2023
  • Carex brevispicula (Cyperaceae) is endemic to Korea and is characterized by constricted achenes, short lateral spikes, and awned staminate and pistillate scales. The species classified in sect. Mitratae occurs throughout South Korea, perennating on mountains and/or rocky slopes under half shadow conditions. Meiotic chromosomes of the species were examined in this study, in which 33 meiotic cells from seven populations were found to be less than 2 ㎛ long with non-constricted chromosomes (n = 34II). The stable chromosome number may be related to the narrow geographical distribution and/or distinct achene morphology. Further investigations of the distribution, morphological character variation, and chromosome characteristics should be conducted with closely related taxa to understand the derivation of the species and its endemism in Korea.

A case of isodicentric chromosome 15 presented with epilepsy and developmental delay

  • Kim, Jon Soo;Park, Jinyu;Min, Byung-Joo;Oh, Sun Kyung;Choi, Jin Sun;Woo, Mi Jung;Chae, Jong-Hee;Kim, Ki Joong;Hwang, Yong Seung;Lim, Byung Chan
    • Clinical and Experimental Pediatrics
    • /
    • v.55 no.12
    • /
    • pp.487-490
    • /
    • 2012
  • We report a case of isodicentric chromosome 15 (idic(15) chromosome), the presence of which resulted in uncontrolled seizures, including epileptic spasms, tonic seizures, and global developmental delay. A 10-month-old female infant was referred to our pediatric neurology clinic because of uncontrolled seizures and global developmental delay. She had generalized tonic-clonic seizures since 7 months of age. At referral, she could not control her head and presented with generalized hypotonia. Her brain magnetic resonance imaging scans and metabolic evaluation results were normal. Routine karyotyping indicated the presence of a supernumerary marker chromosome of unknown origin (47, XX +mar). An array-comparative genomic hybridization (CGH) analysis revealed amplification from 15q11.1 to 15q13.1. Subsequent fluorescence in situ hybridization analysis confirmed a idic(15) chromosome. Array-CGH analysis has the advantage in determining the unknown origin of a supernumerary marker chromosome, and could be a useful method for the genetic diagnosis of epilepsy syndromes associated with various chromosomal aberrations.

Sex Linked Developmental Rate Differences in Murrah Buffalo (Bubalus bubalis) Embryos Fertilized and Cultured In Vitro

  • Sood, S.K.;Chauhan, M.S.;Tomer, O.S.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.12 no.1
    • /
    • pp.15-21
    • /
    • 1999
  • The aim of the present study was to determine the effect of paternal sex chromosome on early development of buffalo embryos fertilized and cultured in vitro. Embryos were produced in vitro from abattoir derived buffalo oocytes. The cleaved embryos were cocultured with buffalo oviductal epithelial cells and evaluated on day 7 under the phase contrast microscope to classify development. The embryos which reached the morula/blastocyst stage were fast developing, the embryos which were at 16-32 cell stage were medium developing and the embryos below 16 cell stage were slow developing. The embryos which showed some fragmentation in the blastomeres or degenerated blastomeres, were degenerating. Sex of emberyos (n=159) was determined using PCR for amplification of a male specific BRY. 1 (301 bp) and a buffalo specific satellite DNA (216 bp) fragments. The results thus obtained show that 1) X and Y chromosome bearing sperms fertilize oocytes to give almost equal numbers of cleaved XX and XY embryos, 2) male embryos develop faster than female embryos to reach advanced stage and 3) degeneration of buffalo embryos is not linked with the paternal sex chromosome. We suggest that faster development of males is due to differential processing of X and Y chromosome within the zygote for its activation and / or differential expression of genes on paternal sex chromosome sex chromosome during development of buffalo embryos fertilized and cultured in vitro which may be attributed to a combination of genetic and environmental factors.

Study on the Somatic Chromosome Numbers of Korean Aster L. and Its Allied Taxa (한국산 개미취속 및 근연 분류군의 체세포염색체수에 관한 연구)

  • 정규영
    • Korean Journal of Plant Resources
    • /
    • v.10 no.4
    • /
    • pp.292-299
    • /
    • 1997
  • The somatic chromosome numbers among the various taxonomic characters about 17 taxa in Korean Aster and its allied taxa were investigated to review accurate scientific name and taxonomic rank. The somatic chromosome numbers of the treated taxa were invariable in same taxa, but variable among different taxa. The treated taxa were divided into two types by basic chromosome numbers, one type was x=9, the other x=8 and x=9 type was subdivided by polyploidy. The somatic chromosome numbers of Aster altaicus var. uchiymae, A. hyatae, Kalimeris chejuensis were reported firstly in this study, and based upon somatic chromosome numbers and leaf morphology, the plants, idenified as Aster pinnatifidus in Korea was considered variant of Kalimeris incisa.

  • PDF

A cytotaxonomic study of Atractylodes japonica Koidz. ex Kitam. and A. macrocephala Koidz.

  • Chung, Gyu-Young;Kim, Mi-Suk
    • Plant Resources
    • /
    • v.3 no.3
    • /
    • pp.179-183
    • /
    • 2000
  • The present study was carried out to clarify the chromosome numbers and karyotype of Atractylodes japonica Koidz. ex Kitam. and A. macrocephala Koidz.. The somatic chromosome numbers of two species were same; basic chromosome number x=12, and somatic chromosome numbers 2n=24. The present result of A. japonica Koidz. ex Kitam. was same to previously reports and that of A. macrocephala Koidz. was reported first in this study. Size and shape of chromosome were some different from A. japonica Koidz. ex Kitam. and A. macrocephala Koidz.. The karyotype of A. japonica Koidz. ex Kitam. was described as follows; 2n : 24 : 8L + 14M +2S : 2 $A^{sm}$ +2 $B^{m}$ +2 $C^{m}$ +2 $D^{st}$ + 2 $E^{m}$ +2 $F^{m}$ +2 $G^{m}$ +2 $H^{sm}$ + 2 $I^{m}$ + 2 $J^{m}$ + 2 $K^{m}$ + 2 $L^{m}$ . And the karyotype of A. macrocephata Koidz. was described as follows; 2n : 24 : 10L +12M +25 : 2 $A^{m}$ +2 $B^{sm}$ +2 $C^{sm}$ +2 $D^{sm}$ +2 $E^{sm}$ +2 $E^{sm}$ +2 $G^{sm}$ +2 $H^{m}$ +2 $I^{m}$ 2 $J^{m}$ +2 $K^{m}$ +2 $L^{m}$ . .

  • PDF