Journal of Dental Anesthesia and Pain Medicine

The Korean Dental Society of Anesthsiology (대한치과마취과학회)
권호 표지
DOI QR코드

DOI QR Code

Anesthetic management of a patient with chromosome 6p duplication: a case report

  • Morinaga, Saori (Department of Dental Anesthesiology, Kyushu University Hospital) ;
  • Tsukamoto, Masanori (Department of Dental Anesthesiology, Kyushu University Hospital) ;
  • Yokoyama, Takeshi (Department of Dental Anesthesiology, Faculty of Dental Science, Kyushu University)
  • Received : 2017.06.05
  • Accepted : 2017.06.16
  • Published : 2017.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Chromosome 6p duplication is very rare and clinically characterized by short stature, mental retardation, and congenital heart diseases. Patients with mental retardation may present with poor oral health conditions. Dental treatment may need to be performed under general anesthesia in such patients. Our case report deals with induction of general anesthesia to a patient with chromosome 6p duplication, for dental treatment. The selection of a nasotracheal tube of an appropriate size, because of the patient's short stature, was especially important for airway management. In the present case, the patient with chromosome 6p duplication was intubated with a nasotracheal tube, which was not age-matched but adapted to the height and physique of the patient.

Keywords

References

  1. Fujii-Abe K, Sasao M, Fukayama H. General anesthesia for a patient with deletion 6q syndrome in addition to laryngomalacia undergoing dental treatment. J Oral Sci 2008; 50(4): 493-5. https://doi.org/10.2334/josnusd.50.493
  2. Smith BS, Pettersen JC, Opitz JM, Reynolds JF. An anatomical study of a duplication 6p based on two sibs. Am J Med Genet 1985; 20: 649-63. https://doi.org/10.1002/ajmg.1320200411
  3. Abe Y, Takamura M, Sawada M, Hisano M, Tsuji Y, Saikawa N, et al. Case of insertion, inversion and deletion of chromosome 6. Pediatr Int 2002; 44(5): 530-3. https://doi.org/10.1046/j.1442-200X.2002.01596.x
  4. Izu A, Yanagida H, Sugimoto K, Fujita S, Okada M, Takemura T. Focal segmental glomerulosclerosis and partial deletion of chromosome 6p: a case report. Clin Nephrol 2011; 76(1): 64-7. https://doi.org/10.5414/CN106587
  5. Jankauskiene A, Koczkowska M, Bjerre A, Bernaciak J, Schaefer F, Lipska-Zietkiewicz BS. Glomerulopathy in patients with distal duplication of chromosome 6p. BMC Nephrol 2016; 17: 32. https://doi.org/10.1186/s12882-016-0246-2
  6. Martin JW, Yoshimoto M, Ludkovski O, Thorner PS, Zielenska M, Squire JA, et al. Analysis of segmental duplications, mouse genome synteny and recurrent cancerassociated amplicons in human chromosome 6p21-p12. Cytogenet Genome Res 2010; 128: 199-213. https://doi.org/10.1159/000308353
  7. Shott SR. Down syndrome: analysis of airway size and a guide for appropriate intubation. Laryngoscope 2000; 110(4): 585-92. https://doi.org/10.1097/00005537-200004000-00010
  8. Eipe N, Barrowman N, Writer H, Doherty D. A weight-based formula for tracheal tube size in children. Paediatr Anaesth 2009; 19(4): 343-8. https://doi.org/10.1111/j.1460-9592.2008.02916.x
  9. Kohjitani A, Iwase Y, Sugiyama K. Sizes and depths of endotracheal tubes for cleft lip and palate children undergoing primary cheiloplasty and palatoplasty. Paediatr Anaesth 2008; 18(9): 845-51. https://doi.org/10.1111/j.1460-9592.2008.02668.x
  10. Tsukamoto M, Hitosugi T, Yokoyama T. Discrepancy between electroencephalography and hemodynamics in a patient with Cockayne syndrome during general anesthesia. J Clin Anesth 2016; 35: 424-6. https://doi.org/10.1016/j.jclinane.2016.09.022

Cited by

  1. Anesthetic Management of a Patient With Fanconi Anemia vol.66, pp.4, 2019, https://doi.org/10.2344/anpr-66-02-06