• 한국운동역학회지
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• 제21권5호
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• pp.645-652
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• 2011

The purpose of this study was to analyze, in real time, the glide motion and release motion of domestic athletes and gold and bronze medalists employing the glide technique for the men's shot put at the Daegu World Athletic Championship in 2011. In the glide motion, the Korean athletes had a relatively high body center and shot put heights and lager stretching angles for their hips and knees. In the delivery phase, which shifts to the release phase, the Korean athletes showed slower vertical body center and shot put speeds, and they changed the phase, to the release phase by using a small body angle. In the release phase, the Korean athletes showed differences in their projection speeds and vertical body center speeds. The world-famous players showed high angle speeds, which refer to the composition of the rotation force at the moment of release (body, hip, and shoulder line). In the release phase, the Korean athletes did not have fully stretched hip and knee angles, which might have negatively influenced the vertical speed. Because the Korean athletes showed relatively low projection heights and projection angles. it was found that they need to enhance the muscular power of their, throwing arms and lower limbs.

• 한국식품영양학회지
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• 제19권2호
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• pp.201-206
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• 2006

Numerous investigators have studied various activities of natural products and have found that they have not only nutritional effects, but also beneficial properties to cure various diseases and to maintain good health. Job's Tear(Yul-Moo) is a grass crop that has long been used in traditional medicine and as a nourishing food. Although its mechanism of action remains unclear, Job's Tear has been reported to exhibit anti-inflammatory, stomachic, anti-allergic, and anti-spastic effects and has been used in China for the treatment of warts, rheumatism, and neuralgia. Previous results in our laboratory demonstrated that the ethanol extract and the water extract of Job's Tear exerted an immune regulatory function on mice cells in vitro. The present study was performed to investigate the ex vivo effect of Job's Tear on immune function. Seven to eight weeks old mice(Balb/c) were fed chow diet ad libitum and water extract of Job's Tear was administered orally every other day for four weeks at two different concentrations(50 and 500mg/kg B.W.). Splenocytes proliferation with mitogen stimulation with Con A and LPS was enhanced at 50 mg/kg B.W. of Job's Tear compared to those of the control group. The results of this ex vivo study showed that proliferation of splenocytes and macrophage activation were seen in the mice orally administrated 50 mg/kg B.W. of Job's Tear water extracts. In conclusion, this study suggests that Job's Tear extracts may enhance immune function by regulating splenocyte proliferation and the cytokine prodution capacity of activated macrophages in mice.

• Preventive Nutrition and Food Science
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• 제21권4호
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• pp.378-383
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• 2016

Diabetic kidney disease is the most common and severe chronic complication of diabetes. The leaf of Diospyros kaki Thumb (persimmon) has been commonly used for herbal tea and medicinal purposes to treat a variety of conditions, including hypertension and atherosclerosis. However, the effect of persimmon leaf on kidney failure has not been investigated. This study aimed to examine the role of persimmon leaf in protecting the diabetes-associated kidney damage in a mouse model of type 2 diabetes. Mice were fed either a normal chow diet with or without powered persimmon leaf (5%, w/w) for 5 weeks. In addition to kidney morphology and blood markers of kidney function, we assessed levels of oxidative stress markers as well as antioxidant enzymes activities and mRNA expression in the kidney. Supplementation of the diet with powered persimmon leaf not only decreased the concentration of blood urea nitrogen in the plasma but also improved glomerular hypertrophy. Furthermore, the persimmon leaf significantly decreased the levels of hydrogen peroxide and lipid peroxide in the kidney. The activities of superoxide dismutase, catalase, and glutathione peroxidase and the mRNA expression of their respective genes were also increased in the kidney of persimmon leaf-supplemented db/db mice. Taken together, these results suggest that supplementation with the persimmon leaf may have protective effects against type 2 diabetes-induced kidney dysfunction and oxidative stress.

• 대한토목학회논문집
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• 제35권2호
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• pp.327-340
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• 2015

기후모형으로 가장 널리 사용되는 GCM의 불확실성 및 시공간적 편의로 인하여 GCM으로부터 생산된 기상정보를 응용수문분야에서 직접적으로 이용하기 위해서는 상세화 과정이 필수적으로 요구된다. 본 연구에서는 선행연구에서 개발된 비정상성 은닉 마코프 모형(Non-stationary Hidden Markov Chain Model, NHMM)을 기반으로 다지점 공간상관성을 고려할 수 있는 Chow-Liu Tree 알고리즘과 결합하여 유역단위 강우시나리오 상세화 기법(CLT-NHMM)으로 확장하였으며, 낙동강 유역에 적용하여 적용성을 평가하였다. 상관행렬(correlation matrix)을 통한 강우네트워크의 공간상관성 평가결과 유역상관성이 우수하게 모의하는 것을 확인하였으며, 강수의 빈도 및 양적 관점에서 효과적인 모의가 가능하였다. 본 연구에서 제시한 CLT-NHMM 모형은 수자원뿐만 아니라 수문자료를 입력 자료로 하는 농업, 보건, 환경 및 에너지 등 다양한 응용기상분야에 핵심 기술로 활용이 전망된다.

• 대한한의학방제학회지
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• 제26권2호
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• pp.113-122
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• 2018

Objectives : Alcoholic fatty liver is an early and reversible consequence of excessive alcohol consumption. The initial hepatocyte cell death stimulates subsequent inflammatory responses, leading to further liver injury and fibrosis. The objective of this study is to investigate the effects of Injinsaryung-san extract on the alcoholic fatty liver by chronic EtOH administration. Method : Male Sprague Dawley rats were used in this study. All animals were randomly divided into Normal group, treated with saline (n=10); EtOH group, treated with ethanol (n=10); EtOH+IS group, treated with ethanol+Injinsaryung-san extract (n=10). For oral administration of ethanol in Control and Sample group, the ethanol was dissolved in distilled water in concentrations of 25%(v/v). Throughout the experiment of 8 week, the rats were allowed free access to water and standard chow. Sample group were administrated by Injinsaryung-san extract daily for 8 weeks. Results : The levels of hepatic marker such as aspartate aminotransferase and alanine aminotransferase were altered. Histopathological changes were reduced and the expression of tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$) was markedly attenuated by Injinsaryung-san extract. Conclusion : These data suggest that Injinsaryung-san extract could be effective in protecting the liver from alcoholic fatty liver. The hepatoprotective mechanisms of Injinsaryung-san may be related to attenuation of $TNF-{\alpha}$ protein, as well as to the inhibition of inflammatory response in the liver. Therefore, Injinsaryung-san can be a candidate to protect against alcoholic fatty liver.

• 대한본초학회지
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• 제26권1호
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• pp.119-124
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• 2011

Objective : This study was carried out to investigate effect of korean medicinal herbs-included hair tonic (MHT) and food (MF) on hair growth in an alopecia model of C57BL/6 mice. Methods : Six-weeks old mice were given laboratory rodent chow diet for 1 week. Then, we used a depilatory for hair removal on mice. The next day, mice were randomized and separated in 3 groups of 6 mice; normal group (N, vehicle epidermal application+normal diet-treated group), positive control group (C, 3% minoxidil sulfate epidermal application+normal diet-treated group), and the treatment group (T, HT epidermal application+ MF diet-treated group). The hair regrowth was determined by photograph, which was taken at 7, 14 and 21 days. And scoring indices, hair density and hair thickness, were evaluated by Folliscope at same day. In addition, the hair regrowth was analyzed insulin-like growth factor (IGF-1) in the dorsal skin of mice. Results : As a result, not only external appearance but also hair density and hair thickness on dorsal skin were increased more in C, T groups than in N group at 21 days with mixed treatment. Therefore, distinct regrowth pattern is appeared by treatment of herbal tonic and natural food for 21 days. Also, the expressions of IGF-1 on dorsal skin were higher in C, T groups than in N group. Conclusion : These results suggested that this herbal hair tonic and natural food has hair growth promoting activities and may be useful for treatment of bald or alopecia.

• Preventive Nutrition and Food Science
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• 제6권2호
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• pp.122-125
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• 2001

A potential mechanism through which the jujube extract might produce a cholesterol-lowering effect was compared with that of tangerine peel extract in vivo. Two extracts were prepared using ethanol. Male rats were fed a high cholesterol (1%, w/w) lab chow with jujube extract (1.2%) or tangerine peel extract (6.3%, w/w) for 3 weeks. Activities of hepatic HMG-CoA reductase (289.6$\pm$12.9 and 296.7$\pm$11.6 nmole/min/mg vs. 347.9$\pm$17.5 nmole/min/mg) and ACAT (554.8$\pm$18.2 and 451.7$\pm$19.4 nmole/min/mg vs. 602.6$\pm$21.4 nmole/min/mg) were significantly lowered by both supplements compared to the control group. These two supplements also substantially reduced the concentrations of plasma cholesterol (103.3$\pm$15.9 and 101.6$\pm$19.4 mg/dL vs. 141.6$\pm$18.1 mg/dL) and triglyceride (61.3$\pm$5.5 and 55.5$\pm$3.9 mg/dL vs. 96.0$\pm$4.2 mg/dL). The inhibition of HMG-CoA reductase resulting from the supplementation of jujube or tangerine extracts could count for the reduction in plasma cholesterol. Accordingly, lipid-lowering action of both supplements appears to be similar in high-cholesterol fed rats.

• Fisheries and Aquatic Sciences
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• 제23권9호
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• pp.24.1-24.9
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• 2020

Brown alga (Ishige okamurae; IO) dietary supplements have been reported to possess anti-diabetic properties. However, the effects of IO supplements have not been evaluated on glucose metabolism in the pancreas and skeletal muscle. C57BL/6 N male mice (age, 7 weeks) were arranged in five groups: a chow diet with 0.9% saline (NFD/saline group), high-fat diet (HFD) with 0.9% saline (HFD/saline group). high-fat diet with 25 mg/kg IO extract (HFD/25/IOE). high-fat diet with 50 mg/kg IO extract (HFD/50/IOE), and high-fat diet with 75 mg/kg IO extract (HFD/75/IOE). After 4 weeks, the plasma, pancreas, and skeletal muscle samples were collected for biochemical analyses. IOE significantly ameliorated glucose tolerance impairment and fasting and 2 h blood glucose level in HFD mice. IOE also stimulated the protein expressions of the glucose transporters (GLUTs) including GLUT2 and GLUT4 and those of their related transcription factors in the pancreases and skeletal muscles of HFD mice, enhanced glucose metabolism, and regulated blood glucose level. Our results suggest Ishige okamurae extract may reduce blood glucose levels by improving glucose metabolism in the pancreas and skeletal muscle in HFD-induced diabetes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제4권4호
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• pp.491-508
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• 2010

In peer-to-peer (P2P) on-demand streaming networks, the alleviation of server load depends on reciprocal stream sharing among peers. In general, on-demand video services enable clients to watch videos from beginning to end. As long as clients are able to buffer the initial part of the video they are watching, on-demand service can provide access to the video to the next clients who request to watch it. Therefore, the key challenge is how to keep the initial part of a video in a peer's buffer for as long as possible, and thus maximize the availability of a video for stream relay. In addition, to address the issues of delivering data on lossy network and providing scalable quality of services for clients, the adoption of multiple description coding (MDC) has been proven as a feasible resolution by much research work. In this paper, we propose a novel caching scheme for P2P on-demand streaming, called Dynamic Buffering. The proposed Dynamic Buffering relies on the feature of MDC to gradually reduce the number of cached descriptions held in a client's buffers, once the buffer is full. Preserving as many initial parts of descriptions in the buffer as possible, instead of losing them all at one time, effectively extends peers’ service time. In addition, this study proposes a description distribution balancing scheme to further improve the use of resources. Simulation experiments show that Dynamic Buffering can make efficient use of cache space, reduce server bandwidth consumption, and increase the number of peers being served.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2004년도 학술발표회
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• pp.681-686
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• 2004

수공구조물의 설계를 위해서는 해당 수공구조물의 중요도에 따른 설계빈도 및 설계유량과 설계수위 등의 설정이라는 과정이 필요하다. 설계빈도는 하천설계기준에 제시되어 있는 바와 같이 시설물의 입지조건과 중요도에 따라 기준이 제시되어 있으며 설계홍수량은 확률강우량을 기초로 한 설계강우를 결정하고, 결정된 설계우량에 의한 유출량의 산정작업이 필요하다. 이와 같은 설계수량의 산정에 있어서 설계강우의 지속기간 설정은 매우 중요한 작업이다. 일반적으로 동일한 설계빈도의 홍수량은 지속기간에 따라 많은 차이를 보이고 있다. 따라서 설계강우의 지속시간 설정은 매우 중요한 설계인자가 되므로 본 연구에서는 IHP유역인 위천유역을 대상으로 최근 권장되고 있는 설계강우의 지속시간 선정을 위한 개념인 임계지속기간을 산정하여 임계지속기간에 영향을 미치는 수문인자들에 대해 살펴보고자 한다. 본 연구에서는 IHP 유역인 위천 유역(동곡 외 4개 소유역)을 대상으로 설계홍수량의 첨두유출량이 최대로 발생하는 강우지속기간을 임계지속기간으로 설정하였으며, 설계홍수량의 산정시 설계강우로부터 홍수량을 산정하기 위한 일련의 절차에서 이용되는 각종 수문요소들, 즉 강우시간분포와 유효우량 산정방법, 유출모형 그리고 면적의 변화에 따른 임계지속기간의 변화를 연구하였다. 본 연구에서는 임계지속기간의 개념을 고려할 설계강우의 지속기간을 산정하기 위해 필요한 각 수문요소별 산정방법은 국내 자료로부터 제안된 방법을 우선 사용하였으며, 임계지속기간의 개념에 따른 설계강우의 지속기간 산정을 위해 확률강우량 산정, 강우의 시간분포(Huff 분포, Yen & Chow의 삼각형 분포), 유효우량 산정방법(AMC-II, AMC-III, CN37), 대표단위도와 6가지 합성단위도법을 적용하였다. 산정 된 결과로부터 임계지속기간 산정에 영향을 주는 각 수문인자 중 강우시간분포와 유효우량 산정방법 그리고 유출모형에 대해 자자 검토하였으며, 최종적으로 면적에 따른 임계지속기간과 유출량의 변화를 검토해 보았다.