• 제목/요약/키워드: Chosun University

검색결과 10,680건 처리시간 0.031초

Cefuroxime axetil의 치주병원성 세균에 대한 최소억제농도와 치은열구액 농도에 관한 실험적 연구 (GCF concentration and minimal inhibitory concentration of cefuroxime axetil against periodontopathogens)

  • 장현선;김재덕;국중기;김화숙;유소영;김미광;김병옥
    • Journal of Periodontal and Implant Science
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    • 제33권3호
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    • pp.341-348
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    • 2003
  • The purpose of this study was to determine the minimal inhibitory concentration (MIC) of cefuroxime axetil, semisynthetic cefalosporin, for some putative periodotopathogens; F. nucleatum, A. actinomycetemcomitans P. intermedia and P. gingivalis. To investigate the efficacy of cefuroxime axetil, several antibiotics, amoxicillin, metronidazole, and ciprofoxacine, were used as control. The MIC was measured by Murray' s method. The MIC of cefuroxime axetil against some putative microbes, as a single use regimen, was relatively high in comparison with that of the other antibiotics used in this study. The MIC of cefuroxime axetil/metronidazole against some putative microbes, as a simultaneous regimen, was similar to that of the other antibiotics used in this study. The manimal level of cefuroxime concentration in gingival fluid was 9${\mu}$/ml at 36hr after the first dose. In conclusion, within the limited experiment, metronidazole/ cefuroxime axetil therapy of periodontitis may provide a therapeutic benefits in reducing the periodontopathogens.

Orthognathic Surgery Using Three-piece Segmental Maxillary Osteotomy to Correct Severe Facial Asymmetry: A Case Report

  • Kim, Seo-Yoon;Kim, Su-Gwan;Oh, Ji-Su;Ahn, Yu-Seok;Moon, Kyung-Nam;Jeon, Woo-Jin;Lee, Jeong-Hoon;Im, Jae-Hyung;Yoo, Kyung-Hwan;Kim, Jin-Ha
    • Journal of Korean Dental Science
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    • 제3권1호
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    • pp.39-42
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    • 2010
  • This case report presents a case that underwent three-piece segmental maxillary osteotomy and sagittal split ramus osteotomy on a patient with severe facial asymmetry accompanied by maxillary prognathism, severe left scissor bite, and chin point deviation. The resulting facial appearance and occlusion were improved, thereby three-piece segmental maxillary osteotomy is regarded effective methed in treating severe facial asymmetry.

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Ewing's Sarcoma of the Stomach; Rare Case of Ewing's Sarcoma and Suggestion of New Treatment Strategy

  • Kim, Hyo-Sin;Kim, Sungsoo;Min, Young-Don;Kee, Keun-Hong;Hong, Ran
    • Journal of Gastric Cancer
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    • 제12권4호
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    • pp.258-261
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    • 2012
  • Ewing's sarcoma is a neoplasm of the undifferenciated small round cells, which generally affects the bone and deep soft tissues of children and adolescents. We present a case of gastric Ewing's sarcoma; a 35-year-old female who had no symptoms. While she was at a routine medical checkup, a protruding mass in her gastric antrum was incidentally found on esophagogastroduodenoscopy. Endoscopic ultrasonogram showed a submucosal mass on the same lesion and a laparosopic wedge resection was done. Pathologic gross findings showed a granular grape appearance tissue and histoloigc examination revealed a small round cell tumor with CD 99 immunoexpression positive. In general, a combined modality therapy for Ewing's sarcoma such as surgical resection with chemotherapy, is accepted as an effective method. However, this patient had no adjuvant chemotherapy after surgery and she has no recurrence for eleven months.

Gram-Positive Bacteria Specific Properties of Silybin Derived from Silybum marianum

  • Lee, Dong-Gun;Kim, Hyung-Keun;Park, Yoon-Kyung;Park, Seong-Cheol;Woo, Eun-Rhan;Jeong, Hye-Gwang;Hahm, Kyung-Soo
    • Archives of Pharmacal Research
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    • 제26권8호
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    • pp.597-600
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    • 2003
  • Silybin has a potent antibacterial activity, more potent than silymarin II, against gram-positive bacteria without hemolytic activity, whereas it has no antimicrobial activity against gram-negative bacteria or fungi. The mode of action of silybin against the gram-positive bacterial cell was examined by investigating the change in plasma membrane dynamics of bacterial cells using 1 ,6-diphenyl-1,3,5-hextriene (DPH) as a membrane probe and by assessing the inhibition of macromolecular synthesis using radiolabeled incorporation assay. The results showed that silybin inhibited RNA and protein synthesis on gram-positive bacteria.