• Title/Summary/Keyword: Chonnam

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Effects of Electroacupuncture on Immobilization Stress Responses : A Study on Inhibitory Avoidance Task, Forced Swimming Test, and Stress Hormones (전기침이 결박 스트레스 반응에 미치는 영향 : 억제성 회피 과제, 강제 수영 시험, 스트레스 호르몬 반응 연구)

  • Kwon, So-Yeon;Kim, Min-Soo;Lee, Sang-Kwan;Je, Jun-Tae;Oh, Jae-Gun;Lee, Jong-Deok;Sung, Kang-Keyng
    • The Journal of Internal Korean Medicine
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    • v.32 no.1
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    • pp.100-112
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    • 2011
  • Objectives : This study investigated the effects of electroacupuncture on memory, depression, and plasma stress hormone levels in rats that were under immobilization stress. Materials and Methods : The immobilization-only group was given two hours of immobilization stress for 10 consecutive days. The immobilization and high frequency EA group was given two hours of immobilization stress simultaneously with high frequency (100Hz) electroacupuncture stimulation on the right ST-36 (Zusanli) for 10 consecutive days. We conducted the inhibitory avoidance and forced swimming tests to recognize whether immobilization stress and electroacupuncture have effects on memory and depression. We collected blood samples from the tail of each rat at 30, 60, 90, and 120-minute intervals during the immobilization stress and EA stimulation to measure plasma concentrations of ACTH, corticosterone, melatonin, and norepinephrine induced by immobilization stress and electroacupuncture. Results : There was a significant effect of high frequency on the increase in anamnesis based on the result of the inhibitory avoidance test, but there was no significant effect of decreasing depression based on the result of the forced swim test. Also, there was no significant effect on the response indicated by stress hormones. Conclusions : 1. High frequency electroacupuncture (100Hz) improved anamnesis in immobilization stress states under the inhibitory avoidance task. 2. High frequency electroacupuncture (100Hz) did not reduce depression induced by immobilization stress under the forced swimming test. 3. High frequency electroacupuncture (100Hz) did not decrease stress hormones through blood sampling.

A Study on the Stiffness of CBA(Corner Block with Anchor Bolt) Joint in Knockdown Type Table Furniture (조립식(組立式) 탁자(卓子)의 CBA접합부(接合部) 강성(剛性)에 관(關)한 연구(硏究))

  • Chung, Woo-Yang;Lee, Phil-Woo
    • Journal of the Korean Wood Science and Technology
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    • v.17 no.2
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    • pp.34-64
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    • 1989
  • Corner block with anchor bolt(CBA) joint method used in knock-down type table furniture manufacturing can reduce the packing and transporting cost. Unfortunately. it also has the disastrous defect to be loosend and unstable during the service life mainly due to fatigue and creep(repeated and prolonged loading). So 22 joint groups constructed were tested to evaluate the effect of some design factors related to the size of side rail(apron). block attachment to side rail. and the number of anchor bolt as well as the effect of the type of corner block(mitered type vs. rectangular type) Usable strength from the stiffness coefficients of each joint group were analysed with SPSS /PC+ and described as the criteria of CBA joint construction. The conclusions were as follows: The height of side rail(50, 75 and 100 mm) and the addition of polyvinyl acetate(PVAc) emulsion in the corner block attactment to side rail had the effect on raising the usable strength of CBA joint with remarkable high significance. And the effect of 2 - anchor bolts was also superior to that of 1 - bolt significantly. However. the thickness of side rail(22 mm vs. 25 mm) had no effect on the strengthening the table joint rigidity. Mitered type corner block joint appeared to he recommendable for CBA jointed table construction rather than the rectangular type one regardless of the method of block attachment to side rail. The best result identified from Duncan's multiple comparison was in the construction with 25 mm thick and 100 mm height of side rail fastened using 2 - anchor bolts in mitered type corner block. But it would be reasonable to use 22 mm thick & 75 mm high side rail and mitered corner block with PVAc emulsion & 2 bolts considering the productivity and production cost down in the MDF furniture manufacturing industries.

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Prediction Equations of Pulmonary Function Parameters Derived from the Forced Expiratory Spirogram for Healthy Adults over 50 years old in rural area (농촌지역 50세 이상 인구의 노력성호기곡선을 이용한 폐활량측정법 검사지표의 추정정상치)

  • Kim, Won-Young;Kim, Kwang-Hyun;Youn, Boung-Han;Lee, Seung-Uk;Cho, Chul-Hyun;Choi, Jin-Su;Kim, Hun-Nam
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.3
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    • pp.536-545
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    • 1998
  • Background: The studies on prediction equations of pulmonary function parameters for adults in Korea have been performed in a reference population mainly consisted of young and middle ages. So they included a relatively few elderly who conducted pulmonary function test frequently in clinic. We established prediction equations of pulmonary function parameters for healthy adults over 50 years old in rural area and compared this results with those of other studies. Therefore we attempted to consider normative values of pulmonary function tests for elderly in Korea. Method: Five hundred thirty-three women and men over 50 years old in rural area were participated. A "healthy" subgroup of 110 women and 32 men were identified by excluding those who had conditions that negatively influenced pulmonary function. We derived prediction equations for FVC, $FEV_1$ and $FEV_1%$ by multiple linear regression method from their age, heights and weights in each sex. Results: Prediction equations for FVC and $FEV_1$ in each sex were derived as follows Male; FVC (L)=0.02488Height(cm)-0.0269Age(years)+0.493 $FEV_1(L)$=0.01874Weight(kg)-0.0282Age(years)+2.906 Female; FVC(L)=0.02160Height(cm)-0.0192Age(years)-0.0125 $FEV_1(L)$=0.01720Height(cm)-0.0194Age(years)+0.3890 Prediction equations for $FEV_1%$ were not derived because $FEV_1%$ didn't have statistically significant terms. Comparing Predicted values that were calculated by substitution into the equations of various studies of mean values of age, heights and weights from this study, FVC and $FEV_1$ values in men of this study were lower than those of other studies. In women, FVC and $FEV_1$ values of this study were as similar as or lower than those of the study conducted for healthy elderly blacks in U.S.A respectively. Conclusion: We have got prediction equations of pulmonary function parameters which were driven from forced expiratory spirogram in adults over 50 years old in rural area. Predicted values of this study were lower than those of other studies which were conducted in Korea. So we consider that the study for spirometry reference values for elderly Korean using the method compatible with ATS recommendation need to be conducted more frequently forward.

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Antioxidative Activities of Extracts from Dried Citrus sunki and C. unshiu Peels (진귤 및 온주밀감 진피의 항산화 활성)

  • Hyon, Jae-Seok;Kang, Sung-Myung;Senevirathne, Mahinda;Koh, Won-Joon;Yang, Tai-Suk;Oh, Myung-Cheol;Oh, Chang-Kyung;Jeon, You-Jin;Kim, Soo-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.1
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    • pp.1-7
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    • 2010
  • This study was carried out to investigate total polyphenol contents, total flavonoid contents and antioxidative activities of the methanol extracts from dried Citrus sunki and C. unshiu peels. The dried C. sunki peels displayed higher total polyphenol and flavonoid contents for older dried peels. In contrast, the dried C. unshiu peels displayed higher total polyphenol contents for more recently dried and displayed high total flavonoid contents by order of 2007, 2008 and 2006. DPPH radical scavenging activities of dried C. sunki peels were high by order of 2007 (0.25 mg/mL exception), 2006 and 2008, but C. unshiu peels could not confirm clear regularity. In particular, the dried C. sunki (2008, exception) and C. unshiu peels displayed very high activities of more than 86% in 1.0 mg/mL. Alkyl radical scavenging activities of dried C. sunki peels were higher for older dried peels (2007, 1.0 mg/mL exception), and that of dried C. unshiu peels were higher for more recently dried in below 0.5 mg/mL but were higher for older peels in 1.0 mg/mL. Hydrogen peroxide scavenging activities of dried C. sunki peels were higher for older peels (2007, 2.5 mg/mL exception), on the other hand, dried C. unshiu were higher for more recently dried. In particular, dried C. unshiu peels displayed high activities of more than 85% in 2.5 mg/mL. Hydroxyl radical scavenging activities of dried C. sunki and C. unshiu peels displayed low activities compared to other reactive oxygen species as the range of $49.9\pm2.2\sim63.5\pm0.9$% in 1.0 mg/mL.

The Formation of the Cenozoic Volcanic Edifice in the Goseong-Ganseong Area, Gangwondo, Korea (강원도 고성-간성일대의 신생대 화산체의 형성과정)

  • Kim, Hwa Sung;Kil, Youngwoo;Lee, Moon Won
    • Journal of the Korean earth science society
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    • v.33 no.7
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    • pp.627-636
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    • 2012
  • In the Obongri-Goseong area of Gangwondo, South Korea, there are six densely distributed volcanic edifices i.e., Duibaejae, Oeumsan, Galmibong, 249 m height, 166 m height, and 102 m height, and two other volcanic edifices including Goseongsan and Unbongsan volcanic edifice that are separately located from a distance. A previously undiscovered 249m volcanic edifice in Obongri was found in this investigation, and the six volcanic edifices distributed in Obongri will be referred to as the Obongri volcanic edifice group. Volcanic edifices in this area were interpreted by other researchers as being volcanic plug, plug dome, and cylindrical volcanic pipe type edifices. The aim of this study is to investigate the aspect of volcanic activity in the Obongri-Goseong area and the formation of volcanic edifices by examining of the shape of volcanic edifices, stratigraphy, and characterization of volcanic products. All the volcanic edifices in the area are composed of basaltic rocks on the Mesozoic granite basement, and the prevalence of the dome shape increased towards the upper part of the mountain. Three volcanic edifices (Duibaejae, 166 m height, 102 m height) include intercalated pyroclastic deposits between the basaltic rocks and the basement. The pyroclastic deposit in the Duibaejae volcanic edifice is composed of quartz, feldspar, granite fragments originated from the basement, and scoria fragments originated from the volcanic eruption. In addition to angular olivine, plagioclase, and pyroxene xenocrysts, all the basaltic rocks contained mantle xenolith, gabbroic xenolith originated from the lower crust, and granitic xenolith originated from the basement. This fact indicates that magma rapidly rose to the surface and that the volcanic activity was explosive. It is also interpreted that, as the basaltic magma became highly viscous due to the large amount of xenocrysts, the erupted magma formed a dome structure on the surface. The original dome structure was then severely eroded out leaving a plug dome formation on the basement.

Community Formation Comparison of Herbaceous Perennials planted on Urban Stream Levee Slope (도시하천 제방사면에 식재한 다년생 초본류의 군락 형성 비교)

  • Yang, Hong-Mo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.1
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    • pp.133-148
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    • 2014
  • In order to investigate community formation ability, herbaceous perennials such as Miscanthus sacchariflorus Bentham, Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne, Pennisetum alopecuroides (L.) Spreng. and Arundinella hirta Tanaka were planted in April 2009 at the levee slope of Gwangju Stream in South Korea. Miscanthus sacchariflorus Bentham, Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne and Pennisetum alopecuroides (L.) Spreng. which grew in pots for two years and divided rhizomes of Arundinella hirta Tanaka gathered from fields were employed. Weeds growing on the experiment sites were removed twice a year until 2011 when the plant species were formed into community. Weeds were not eradicated during 2012 and 2013 to observe community sustainability of the species. T-tests on stem numbers and heights in May, July and September were conducted between 2011 and 2012, and between 2012 and 2013. Stem numbers of the five species in 2012 were significantly reduced(p<0.001) compared with those in 2011, which were attributed to weed growth in 2012. Heights of Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne, Pennisetum alopecuroides (L.) Spreng. and Arundinella hirta Tanaka in 2012 were significantly lower than those in 2011(p<0.001), which resulted from weed invasion. Heights of Miscanthus sacchariflorus Bentham in May and July 2012 were significantly decreased compared with those in 2011(p<0.001), however, heights of Miscanthus sacchariflorus Bentham in September 2012 were almost the same as those in 2011(p>0.05). Miscanthus sacchariflorus Bentham was able to compete against weeds in September 2012. Stem numbers and heights of Miscanthus sacchariflorus Bentham, Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne and Pennisetum alopecuroides (L.) Spreng. in 2013 were similar to those in 2012(p>0.05). However, stem numbers and heights of Arundinella hirta Tanaka in 2013 were significantly decreased compared with those in 2012(p<0.001). After community formation, Miscanthus sacchariflorus Bentham, Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne and Pennisetum alopecuroides (L.) Spreng. were able to maintain its community without weed removal. However, Arundinella hirta Tanaka was unable to establish its community due to the weed growth. Miscanthus sacchariflorus Bentham, Miscanthus sinensis var. purpurascens Rendle, Imperata cylindrica Linne are more suitable to stream levee slope environment in terms of community formation and maintenance, stream landscape enhancement and slope erosion control.

A Study on a Changed Power of Tear lens at Spherical RGP lens Fitting (구면 RGP렌즈 Fitting시 누액렌즈 굴절력 변화에 대한 연구)

  • Park, Seong-Jong;Joo, Seok-Hee;Jung, Ju-Hyun
    • Journal of Korean Ophthalmic Optics Society
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    • v.9 no.2
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    • pp.455-462
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    • 2004
  • In this paper, we measured and analysised the power change of tear lens for 85 patients - 170 myopia eyes - who are fitted using RGP lens, considering the BGR of RGP lens, the corneal astigmatism power, and corneal curvature. We got the following results from these experiments; 1. When the BCR of RGP lens changes, the diopters of tear lens of "on-k", 0.05Pt, 01.0Ft, 0.05St, and 0.10St are -0.25D, -0.46D, -0.63D, +0.07D, and +0.26D, respectively. 2. When the corneal astigmatism power changes, the diopters of tear lens of group below 0.75D, group of 1.00D~1.25D, group of 1.50D~1.75D, and group over 2.00D in "on-k" state, are -0.25D, -0.18D, -0.09D, and -0.39D, respectively. 3. When the corneal astigmatism power changes and the BCR of test lens is changed by 0.05mm step, the change values of tear lens diopter for 0.05St and 0.05Ft approximate to ${\pm}0.25D$, while these for 0.10St and 0.10Ft don't approximate to the value below ${\pm}0.25D$.[are irregular value below ${\pm}0.25D$.] 4. When the corneal curvature and the HCR of RGP lens change, the diopters of tear lens of group below 7.50mm, group of 7.55~7.80mm, group of 7.85~8.20mm, and group over 8.25mm in "on-k" state, are -0.40D, -0.11D, -0.20D, and -0.19D, respectively. 5. When the BCR of test lens is changed by 0.05mm step and the corneal curvature increases, the change values of tear lens diopter decrease, while these over 8.25mm are mean value ${\pm}0.17D$ and the value below ${\pm}0.25D$.

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Long-term Clinical Outcomes after Primary Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction-on the basis of 65 Years (급성 심근경색증 환자에서 일차적 관상동맥 중재술 후 장기적 임상 경과-65세를 기준으로)

  • Lee, Han-Ol;Jang, Seong-Joo;Kim, In-Soo;Han, Jae-Bok;Park, Soo-Hwan;Kim, Jeong-Hun;Jang, Young-Ill
    • The Journal of the Korea Contents Association
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    • v.14 no.5
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    • pp.251-261
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    • 2014
  • Primary percutaneous coronary intervention (PCI) has been found to be superior, in terms of hospital mortality and long-term outcome, compared with thrombolytic therapy in patients with acute myocardial infarction (AMI). However, the clinical benefits of primary PCI have not been precisely evaluated in elderly patients.1,974 patients (Group I: n=1,018, $age{\geq}65years$, $73.8{\pm}5.99years$; Group II: n=956, age<65years, $52.8{\pm}7.96years$) who underwent primary PCI for AMI at Chonnam National University Hospital between 2006 and 2010 were analyzed according to their clinical, angiographic characteristics for hospital and one-year survival. Group I had a higher percentage of women, diabetes mellitus, hypertension, multi-vessel disease and lower prevalence of current smoking, hyperlipidemia, familial history than Group II. Culprit lesions were at the left anterior descending artery, left circumflex artery, right coronary artery and left main artery in 42.8% vs. 45.0%, 34.1% vs. 29.6%, 14.6% vs 14.6, 2.7% vs. 1.6%, respectively (p=0.007). Stent diameter was smaller in group I ($3.17{\pm}0.39$ vs. $3.29{\pm}0.42mm$, p=0.001). In-hospital mortality was higher in group I (8.4 vs. 1.9%, p<0.001). There were significant differences in the rates of major adverse cardiac events between the two groups during one-year clinical follow-up (20.1 vs.14.0%, p<0.001). On multiple logistic regression analysis, systolic blood pressure<100mmHg, serum $creatinine{\geq}1.3mg/dL$, Killip class> I, multivessel disease, left ventricular ejection fraction <40% and cerebro vascular disease were independent predictors of one-year motality in patients over 65 years after PCI.

Biodistribution of Iodine-131-Iodomisonidazole and Imaging of Tumor Hypoxia in Mice bearing CT-26 Adenocarcinoma (CT-26 선암을 접종한 마우스에서 Iodine-131-Iodomisonidazole의 생체분포 및 종양저산소증의 영상화)

  • Kim, Hye-Won;Kim, Chang-Guhn;Yoon, Kwon-Ha;Kim, Hyun-Jeong;Juhng Seon-Kwan;Roh, Byung-Suk;Yang, David J.;Kim, E.Edmund;Lee, Hyun-Chul
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.3
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    • pp.289-297
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    • 1999
  • Purpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. Materials and Methods: Tosyl precursor was dissolved in acetonitrile and I-131-NaI was added to synthesize IMISO. Balb/c mice inoculated with CT-26 adenocarcinoma were injected with IMISO. Mice were sacrificed at 1, 2, 4, 24 hr and % of injected dose per gram of tissue (%ID/g) was determined. For scintigraphy and MRI, mouse bearing CT-26 adenocarcinoma was administered with IMISO and imaging was performed 4 hr after. Then, mouse body was fixed and microtomized slice was placed on radiographic film for autoradiography Results: %ID/g of tumor was 1.64 (1h), 0.98 (2h), 0.85 (4h) and 0.20 (24h), respectively. At 24h, %ID/g of tumor was higher than that of all other tissues except thyroid. Tumor to muscle ratio increased with time and tumor to blood ratio also increased with time and reached 1.53 at 24 hr. On autoradiogram, tumor was well visualized as an increased activity in central hypoxic area of the tumor which corresponds to the area of high signal intensity on T2-weighted MR image. On scintigraphy, tumor uptake was visualized. Conclusion: This results suggest that IMISO may have a potential for tumor hypoxia imaging in mouse model. However, further study is needed to improve it's localization in tumor tissue and to achieve acceptable images of tumor hypoxia.

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Studies on the amino acid metabolism of young rice root (Part 3) - Effects of nitrogen, phosphorus, potassium and respiratory inhibitor on the enzyme activities of rice root - (수도근(水稻根)의 Amino산(酸) 대사(代謝)에 관한 연구 -제(第) 3 보(報) 수도근(水稻根)의 몇가지 효소(酵素)의 활성(活性)에 미치는 삼요소(三要素)및 호흡저해제(呼吸沮害劑)의 영향(影響))

  • Kim, Young Ung
    • Korean Journal of Soil Science and Fertilizer
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    • v.7 no.4
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    • pp.201-207
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    • 1974
  • Some effects of nitrogen, phosphorus, potassium and respiratory inhibitor on growth of rice plant and activity of GOT, GPT and peroxidase for the rice root were investigated. Obtained results were summarized as follows: 1. Growth of rice root and plant applied with $NO_3$-N in culture solution was generally increased in the length and weight compared with that of $NH_4$-N plot. On the other hand, the GOT, GPT and peroxidase activity was more increased in the $NH_4$-N plot than in the $NO_3$-N plot. 2. Oxidative power of ${\alpha}$-naphthylamine in rice root was stronger in the $NO_3$-N plot than in the $NH_4$-N plot. 3. When rice plant was cultured in the medium which did not supplied nitrogen, phosphorus or potassium, respectively, GOT activity was more decreased than GPT activity, while peroxidase activity was increased mostly in the potassium-free plot. 4. When rice plant was cultivated in the culture solution added respiratory inhibitor, NaF, plant height was shortened in the order of nitrogen-free > $NH_4$-H > urea-N > $NO_3$-N plot, and GOT and GPT activity was also decreased in the order of nitrogen-free > $NH_4$-N > urea-N > $NO_3$-N plot.

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