• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.320-327
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• 2021

Objective: The community has implemented a variety of exercise programs for the elderly population. However, studies comparing changes in the cardiovascular system through body composition and blood analysis after applying aqua aerobic exercise are insufficient. The purpose of this study was to investigate the effect of a 12 weeks aqua exercise on body composition and cardiovascular index in elderly women. Design: Non-equivalence pre-post design. Methods: Thirty elderly women were assigned to aquarobic group(n=15) and control group(n=15). The aquarobic exercise was 60 minutes per every session, 2times per week, for 12weeks. Weight, skeletal muscle mass, body fat percentage, total cholesterol, triglyceride, HDL cholesterol, and LDL cholesterol were measured before and after the exercise program. Paired and independent t-tests were performed using SPSS program. Results: The result showed was weight(p<0.05), body fat percentage(p<0.05), total cholesterol(p<0.05), triglyceride(p<0.05), HDL cholesterol(p<0.05), and LDL cholesterol(p<0.05) were significantly decreased and skeletal muscle mass(p>0.05) was not significantly increased after aquatic exercise program. Conclusions: According to the study result, aqua exercise program made a positive effect in the improvement of obesity and cardiovascular function in elderly women. Therefore, we suggest that you actively consider implementing the Aquarobic exercise program when operating the community health promotion program in the future. In addition, in future studies, comparative studies according to various ages and genders and studies on the effects of aqua aerobic exercise as a community exercise program for chronically illness patients are needed.

• Journal of Nutrition and Health
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• v.18 no.2
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• pp.83-89
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• 1985

The present study was conducted to estimate the effects of dietary cholesterol on plasma cholesterol concentration, plasma lipoprotein pattern and cholesterol concentration of various tissues. Male and female, Sprague - Dawley rats were fed for 4weeks the diets providing various levels of cholesterol as 0.0, 0.2, 0.5 and 1.0%, respectively. Plasma total cholesterol concentration was little sensitive to dietary levels of cholesterol, while plasma lipoprotein pattern and cholesterol concentration of tissues were sensitive. That is, the higher the level of dietary cholesterol, the lower the propotion of HDL fraction, but the higher that of VLDL fraction. Cholesterol concentrations of liver and skeletal muscle were significantly increased by the dietary levels of cholesterol. However, no significant change was found in adipose tissue.

• Korean Journal of Food Science and Technology
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• v.30 no.3
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• pp.693-696
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• 1998

Chitosan is the deacetylated product of chitin. Chitosan and its derivatives have many properties that make them attractive for a wide variety of health applications. This study was performed to investigate some effects of water soluble chitooligosaccharides on liver function in the mouse. The animals given the sterol diet containing 3% cholesterol for 6 weeks showed increase in plasma cholesterol level, which were lowered by 23% when they were fed on 1% chotooligosaccharide. While there was no significant change in liver cholesterol and plasma HDL-cholesterol levels. Continuous administration of 15% ethanol via drinking water to mice for 8 weeks elicited pathological alterations such as inflammation, necrosis, accumulation of lipid droplets in the liver and increase in GPT activity, while simultaneous administration of ethanol and chitooligosaccharide prevented remarkedly ethanol-induced liver injury; there was no observable lipid droplet and GPT activity was decreased by 25% in the liver. These results suggest that chitooligosaccharide play some roles in liver function, such as reducing the plasma cholesterol level and preventing alcoholic liver disease.

• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.4
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• pp.718-723
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• 1998

This study was designed to observe the effects of the feeding of Hijikia fusiforme(Harvey) Okamura juice extract on the improvement of lipids in the serum of cholesterol-supplemented diet induced dietary hyperlipidemic rats fed experimental diets for 4 weeks. Concentration of total cholesterol and LDL-choloesterol in serum was significantly lower in the Hijikia fusiforme juice extract group than in the cholestero diet group. Concentration of HDL-cholesterol in serum was higher in the Hijikia fusiforme juice extract group than the cholesterol supplemented diet group. Those in the Hijikia fusiforme juice extract group were higher than those in the cholesterol diet group. In the ration of HDL-cholesterol concentration to total cholesterol concentration, Hijikia fusiforme juice extract administration group was higher percentage than the other groups. Atherosclerotic index was lower in the Hijikia fusiforme juice extract group than in the cholesterol diet group. Concentration of free cholesterol and cholesteryl ester in serum was rather lower in the Hijikia fusiforme juice extract group than the other groups. Triglyceride concentration in serum was significantly lower in the Hijikia fusiforme juice extract group than in the cholesterol diet group. Concentration of phospholipid in serum was more decreased in the Hijikia fusiforme juice extract group than in the cholesterol diet group. The activities of aspartate aminotransferase and alanine aminotransferase in serum were rather lower in the Hijikia fusiforme juice extract group than the cholesterol supplemented diet group. From the avove research, the Hijikia fusiforme juice extracts were effective on the improvement of the lipid compositions in serum of high fat diet induced dietary hyperlipidemic rats.

• Journal of Life Science
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• v.12 no.1
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• pp.106-112
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• 2002

Ethanol extract of Cinnamomi cortex inhibited potently cholesterol esterase activity in vitro. Chloroform fraction of ethanol extract showed the stronger inhibitory effect than other solvent fractions - ethylacetate fraction, butanol fraction, and aqueous fraction. The chloroform fraction of Cinnamomi cortex was studied as a candidator of plasma cholesterol-lowering material using high cholesterol-fed rats. In high cholesterol-fed rats, the diet with chloroform fraction of 150 mg/kg lowered not only plasma neutral lipids contents 25.1% but also plasma total cholesterol level 49.6% than only high cholesterol diet. Plasma HDL-cholesterol level in Cinnamomi cortex chloroform fraction-fed rats was recovered as those level of normal rats. LD$_{50}$ of Cinnamomi chloroform extract was calculated as 1,300 mg/kg.

• Journal of Haehwa Medicine
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• v.12 no.2
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• pp.1-9
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• 2004

1. Purpose Stroke is the most frequent cause of mortality and morbidity rate in Korea with coronary heart disease and cancer. The ischemic type of stroke is increasing tendency. The purpose of this studies is to examine the hematologic difference between cb infarction patients and Korean normal adults. 2. Method The study group consisted of neurologically confirmd 50 cb-infarction patients as the case group and 278 patients as control group that they had no significant result by CT through early examination of stroke in Cheonan oriental hospital of Daejeon university. We tested and compared RBC, hemoglobin, hematocrit, WBC, PT, PTT, total protein, albumin, total bilirubin, direct bilirubin, GOT GPT, $\gamma$-GTP, total cholesterol, triglyceride, HDL-C, glucose, BUN, creatinine, Na, K in the both group. 3. Result In the sample group(cb infarction group), there were many patients with low RBC count but no significant and with low hemoglobin, hematocrit(p<0.05). Thereas, increased WBC count and delayed PTT were showed respectively 20%, 36% in patient group, 7.9%, 4.7% in normal group(p<0.05). Comparing the LFT between cb infarction patients and normal adults, we founded significant cases with low HDL-C level, high glucose level, low potassium level in patient group(p<0.05). But the percentage of high total cholesterol level and triglyceride level were 18%, 29%(norma1 group), 20%, 28%(cb infarction group) respectively, there were no significant difference. 4. Conclusion In this study, we demonstrated that low HDL-C level and high glucose level is one of important risk factor of cb infarction. Also prospective studies are needed to evaluate many risk factor(hemoglobin, hematocrit, WBC, cholesterol, triglyceride, K, etc) of cb infarction.

• Korean Journal of Community Nutrition
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• v.6 no.2
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• pp.162-171
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• 2001

This study was performed to investigate the relationship between obesity, health-related lifestyle, and dietary intake and serum lipid level in 96 male university students. Health-related lifestyle factors were obtained from questionnaires. Dietary intakes were evaluated with one-day 24-hr recall and two-day dietary record. Anthoropometric data were recorded and serum cholesterol and triacylglycerol concentrations were measured. 21.9%, 36.5%, 36.5%, and 6.2% of the subjects had levels beyond the normal range in serum total cholesterol(TC), HDL-cholesterol(HDL-C), LDL-cholesterol(LDL-C), and triacyglycerol respectively, and 57.3% of the subjects had more than one hyperlipidemic factor. TC was correlated positively with BMI(p〈0.01), waist length(p〈0.05), hip length(p〈0.05), and the amount of smoking(p〈0.05). HDL-C was correlated negatively with BMI(p〈0.05) and hip lenghth(p〈0.05). LTD-C was correlated positively with BMI(p〈0.01), water length(p〈0.05), hip length(p〈0.01), and coffee consumption(p〈0.05). TG was correlated positively with waist length(p〈0.01), waist-to-hip ratio(p〈0.05), and amount of smoking(p〈0.01) and negatively correlated with frequence of exercise(p〈0.05). Among nutrient intakes, only the ratio of protein to energy was correlated negatively with TC(p〈0.05). Logistic regression analysis revealed that BMI, waist length, hip length, waist-to-hip ratio, and amount of cigarette smoking were associated with an increased risk of hyper-TC. BMI, waist length, and hip length were associated with an increased risk of hypo-HDL-C. BMI and coffee consumption were associated with an increased risk of hyper-LDL-C. Amount of cigarette smoking was associated with an increased risk of hyper-TG. In conclusion, a high prevalence of hyperlipidemia in subjects was observed. Also obesity, smoking, and coffee consumption were observed to be highly with the risk of hyperlipidemia in subjects. These findings imply that these factors should be primarily considered in planing the nutrition education program for the prevention of cardiovascular disease in male university students.

• Journal of Korean Physical Therapy Science
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• v.15 no.2
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• pp.1-13
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• 2008

Background: This study had been carried out with 18 ischemic stroke patients as its object for about eight months from October, 2006 to May, 2007 in order to observe the recovery of motor function and the change of important blood factors according to the different quantitative exercises. Methods: Subjects were assigned randomly either experimental group (n＝19) or the control group (n＝19), when the study began the halfway on this study dropout 20 patients, and final subjects remained experimental group's 9 patients and control group's 9 patients. Both groups received thermotherapy and functional electrical stimulation (FES), also taken different quantitative exercise therapy (experimental group 180 minutes, control group 80 minutes). Subjects were assessed for upper and lower extremities motor function Fugl－Meyer Scale; FMS), blood test (white blood count; WBC, low density lipoprotein －cholesterol; LDL-C, high density lipoprotein-cholesterol; HDL-C, Troponin) during pretest, after 2 months, after 3 months. Results: The results of this study were as follows; 1. FMS has no statistically significant difference with intergroup(p>.05). But there was a statistically significant difference with each groups (p<.05). 2. WBC has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 3. LDL-C has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 4. HDL-C has no statistically significant difference with intergroup (p<.05). But there was a statistically significant difference with each groups (p>.05). 5. Troponin Ⅰ has no statistically significant difference with intergroup (p>.05). Also there was no statistically significant difference with each groups (p>.05). Conclusion: These findings suggest that different quantitative exercises has no effect on FMS, LDL-C, HDL-C, WBC, Troponin Ⅰ with ischemic stroke patients. But the treatment period that there's less correlation between the recovery of motor function and the different quantitative exercise, also less correlation between the change of important blood factors and the different quantitative exercises with ischemic stroke patients.

• Journal of Nutrition and Health
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• v.41 no.3
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• pp.232-241
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• 2008

Moderate alcohol consumption has been known to be associated with reduced risk for coronary heart disease (CHD). We assessed the association between alcohol consumption and CHD-related risk factors [hypertension, diabetes mellitus (DM) , high total cholesterol, high triglyceride (TG), low HDL-cholesterol (HDL-C), and high LDL-cholesterol (LDL-C)] in Korean. After excluding those with extreme intake values, the number of final subjects included in the analysis was 4,662 Korean adults aged over 20 years (1,961 men, 2,701 women) who participate in the 2005 Korean National Health and Nutrition Examination Survey. The subjects were divided into four or five groups; none-alcohol consumption group, moderate alcohol consumption group (<15 or 15.0-29.9 g/d), heavy alcohol consumption group (30-69.9 g/d or ${\geq}$ 70 g/d in men, ${\geq}$ 30 g/d in women). Odds ratios (ORs) were estimated from logistic regression adjusting for potential covariates. Alcohol consumption was inversely associated with low HDL-C in both men and women. However, heavy alcohol intake (${\geq}$ 70 g/d) significantly increased risk for hypertension, DM, and hypertriglyceridemia in men. The frequency of alcohol intake was also associated with CHD risk. The risk for low HDLC was decreased with alcohol consumption (${\geq}$ 1 times/wk), but frequent alcohol intake (${\geq}$ 4 times/wk) increased the risk for hypertension. This study revealed that moderate alcohol consumption has protective effect on CHD-related risk factors in Korean population.

• Journal of the Korean Data and Information Science Society
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• v.23 no.4
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• pp.649-656
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• 2012

The present study was carried out to summarize the effect of caffeine in the lipid metabolic by meta-analysis. The association measure to test effect of caffeine was the Hedges's standardized mean difference (HG). In this particular fixed-effect model of Hedges's standardized mean difference, weight gain, heart weight, serum total lipid, serum triglycerides and liver triglycerides were significantly decreased (p < 0.05). Also, serum HDL cholesterol and serum LDL cholesterol were significantly increased. In this case of heterogeneous variable, random effect model was applied. In this model, weight gain, heart weight, serum total lipid, serum triglycerides, serum LDL cholesterol and liver triglycerides were significantly decreased in caffeine treated group. Also HDL-cholesterol was significantly increased in caffeine treated group.