• 대한기관식도과학회지
• /
• 제8권1호
• /
• pp.61-65
• /
• 2002

Background : Acquired tracheoesophageal fistula(TEF) results mostly from Prolonged tracheal intubation and insertion of nasogastric tube. Although the incidence has decreased since the usage of low pressure, high volume cuff of endotracheal tube, it is seldom cured spontaneously and needs surgical treatment. Material and Methods : We have retrospectively reviewed five cases of TEF who underwent surgical treatment for cure from March, 1990 to September, 2001 and analyzed the cause, treatment, postoperative complications and prognostic factors. Results : Majority were men(80% : 4 of 5 patients) and the mean age was 29.4 years old(range, 11-58). The most predominant etiology was prolonged intubation or tracheostomy(80% : 4 of 5 patients) and 3 of 5 patients were treated by tracheal resection and end to end anastomosis with primary closure of esophagus. Postoperative complications occurred in 4 patients the most common complications were wound infection(4 cases) and esophageal leakage(2 cases). Extubation was done on postoperative day 11.5(range, 1-33) days, and factors causing delayed extubation were status esophagus. epilepticus, edema, and tracheal stenosis. Conclusion : Spontaneous closure of TEF is seldom possible and the surgical treatment of choice is tracheal resection and end to end anastomosis with primary repair of the esophagus. preoperative pulmonary rehabilitation and early extubation postoperatively are important factors for success.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제12권1호
• /
• pp.70-74
• /
• 2009

저자들은 급성 복통을 주소로 내원한 10세 남아에서 복부 초음파와 복부 전산화단층촬영을 통하여 대망 경색을 진단하였으며 항생제 및 진통제 등의 보존적인 치료로 증상의 완화를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제22권3호
• /
• pp.227-231
• /
• 2022

Although rare, complications can occur with anesthetic procedures. The posterior superior alveolar nerve (PSAN) block anesthetic technique has a high success rate, but positive aspiration can cause bruising, transient diplopia, blurred vision, and temporary blindness in approximately 3% cases. When edema occurs, it is occasionally massive, especially in the infratemporal fossa, and the resulting hematoma is usually unsightly. A 20-year-old woman presented with massive edema followed by hematoma in the upper right jaw immediately after PSAN block administration, which subsequently spread to the oral mucosa. The patient did not report any complications during the anesthetic procedure. However, after the injection was administered, the patient experienced anesthetic sensations, which rapidly evolved to facial edema. There was mild pain, but without intraoral or extraoral bleeding. The patient was prescribed medicines and instructed to perform contrast therapy. Although hematomas and edema are rare, they are difficult to prevent. The choice of local anesthetic and appropriate application of the anesthetic technique can minimize their occurrence.

• Archives of Plastic Surgery
• /
• 제51권1호
• /
• pp.67-71
• /
• 2024

Clavicle fractures are frequent injuries accounting for approximately 4% of all fractures in adults with about 35% occurring in the shoulder region among which midshaft fractures are the most common (>66%). Nonsurgical management is the treatment of choice for most clavicle fractures; however, poor functional and aesthetic outcomes may result from nonunion, symptomatic malunion, and aesthetic impairment which are the most common complications. A young woman was referred to our clinic for a "Step Deformity" resulting after primary, nonsurgical treatment of a midshaft clavicle fracture. Residual deformity was corrected with a novel simple and little invasive approach. Midshaft clavicle fractures typically only require conservative nonsurgical treatment, nevertheless suboptimal outcomes may occur. Selective osteotomies and fixation are deemed too invasive when only cosmetic impairment of the clavicle contour is present without any functional or sensitive damage and most patients are discouraged from undergoing surgery. Thus far, no specific focus on this topic, nor exploration of possible correction can be found in the published literature. These residual deformities may be very noticeable sometimes and cause psychological distress and social life impairment. Despite no related functional impairment, this deformity should still be addressed, to improve patients' quality of life.

• 대한화장품학회지
• /
• 제23권2호
• /
• pp.63-70
• /
• 1997

It has been observed that local increase in melanin synthesis or uneven distribution can cause local hyperpigmintation or spot. Pigmentary disorders are caused by various factors, including inflammation, imbalance of hormones, and genetic disorder. Recently the harmfulness of Ultraviolet radiation is increasing due to destruction of ozone layer. Excessive exposure to UV radiation caused post-inflammatory pigmentation. Most women want to avoid uneven skin pigmentation. To satisfy this desire many cosmetic companies have been developing melanogenesis inhibitors and finding promising active agents for use in cosmetic preparations for skin whitening. In cosmetic preparations, many inhibitors such as kojic acid, arbutin, ascorbic acid, and licorice extracts6 have been used as whitening purpose. Plant extracts having an inhibitory effect on melanin formation may be a good choice for cosmetic purpose because of their relatively lower side effects. Therefore, we screened 285 plant extracts for their inhibitory activity in tyrosinase. Of the plant extracts, ramulus mori extracts showed potent tyrosinase inhibition activity. We also identified the active compound in the extract.

• Journal of Chest Surgery
• /
• 제41권4호
• /
• pp.520-522
• /
• 2008

원발성 대동맥-식도 누공은 드문 질환으로 식도 내로 대량의 출혈을 일으키는 치명적인 질환이다. 원인으로는 흉부 대동맥류가 가장 흔하며, 암에 의한 궤양, 염증 등이 있다. 수술이 근치적 치료 방법이지만 유병률과 사망률이 높으며, 최근에는 스텐트-그라프트를 이용한 비수술적 치료 방법이 소개되고 있다. 저자들은 수술을 통해 누공을 박리하고 식도와 대동맥을 일차 봉합하여 치료한 원발성 대동맥-식도 누공 1예를 문헌 고찰과 함께 보고한다.

• 정보관리연구
• /
• 제30권2호
• /
• pp.20-30
• /
• 1999

본고는 경제재로서의 정보의 성질, 이에 따른 시장거래와 관련된 문제, 기술정보정책에 대한 의미를 살펴봄으로써 기술정보의 생산과 시장거래와 관련된 문제를 다룬다. 이를 위해 우선 정보시장의 일반적 특집을 살펴보고, 다음으로 정보과잉의 출현, 정보의 공급과 품질, 정보의 선택과 같은 문제를 다룬다. 그리고 시장이 정보의 생산과 거래를 어떻게 촉진시킬 수 있으며, 유용한 정보를 어떻게 선택할 수 있는지를 분석한다. 끝으로, 정보재 시장의 특징이 국가 기술정보 유통에 의미하는 바를 고찰한다.

• Journal of Digestive Cancer Research
• /
• 제6권2호
• /
• pp.64-68
• /
• 2018

Pancreatic ductal adenocarcinoma is a dismal prognosis and 5^th leading cause of cancer related death in Korea. A large proportion of patients are diagnosed at advanced or metastatic stage. Therefore systemic chemotherapy has become the mainstay of treatment for pancreatic cancer. For most patients advanced or metastatic pancreatic cancer that has a good Eastern Cooperative Oncology Group performance status (ECOG PS) 0 or 1, we can recommend for FOLFIRINOX (leucovorin, 5-fluorouracil [5-FU], irinotecan and oxaliplatin) and gemcitabine plus nanoparticle albumin-bound paclitaxel (nab-paclitaxel). Currently, steps towards improved therapeutic efficacy of palliative chemotherapy have been made by introducing these regimens. For patients with an ECOG PS of 2, gemcitabine monotherapy or S1 alone is recommended. The second-line therapy for patients initially treated with gemcitabine-based chemotherapy includes provide FOLFOX (leucovorin, 5-FU, and oxaliplatin), capecitabine plus oxaliplatin, and 5-FU plus liposomal irinotecan. The gemcitabine-based chemotherapy is a reasonable choice for patients treated with FOLFIRINOX. Currently, studies on selecting patients for biomarkers related to molecular biologic features of tumors are underway for the realization of precise medicine, and the development and verification of preclinical models for the development of new therapeutic agents are being carried out continuously.

• 한국치위생학회지
• /
• 제14권2호
• /
• pp.131-137
• /
• 2014

Objectives : The aim of the study is to investigate anxiety, fatigue and stress of dental hygiene students in clinical practice and to improve the psychological support program. Methods : A self-reported questionnaire was filled out by 428 dental hygiene students in 4 universities in Gwagju and Jeonnam. Data were analyzed for anxiety, stress and fatigue, general characteristics using SPSS 18.0 program for descriptive statistics, ANOVA, and correlation. Results : Saliva suction showed the most high score in treatment($mean{\pm}SD=2.92{\pm}1.13$) and was followed by children dental care($2.79{\pm}1.21$), preventive dental care($2.38{\pm}1.04$), maxillofacial radiology($2.35{\pm}1.15$). During the clinical practice, students felt uneasy when they stayed in relative home(p<0.05). Poor interpersonal relation(p<0.001), poor health condition(p<0.01), low satisfaction with major(p<0.01), the other cause of major choice(p<0.01) influenced on their stress. Satisfaction with major was closely related to clinical practice performance, anxiety, physical fatigue and mental fatigue. Conclusions : In order to reduce physical, mental, neuro sensory fatigue of students in clinical practice, it is recommended to reinforce the patient care etiquettes in curricula.

• Geomechanics and Engineering
• /
• 제30권3호
• /
• pp.313-324
• /
• 2022

With the development of the economy, people's utilization of underground space are also improved, and a large number of cities have begun to build subways to relieve traffic pressure. The choice of subway station construction method is crucial. If an inappropriate construction method is selected, it will not only waste costs but also cause excessive deformation that may also threaten construction safety. In this paper, a subway station construction scheme selects model based on the AHP-fuzzy comprehensive evaluation. The rationality of the model is verified using numerical simulation and monitoring measurement data. Firstly, considering the economy and safety, a comprehensive evaluation system is established by selecting several indicators. Then, the analytic hierarchy process is used to determine the weight of the evaluation index, and the dimensionless membership in the fuzzy comprehensive evaluation method is used to evaluate the advantages and disadvantages of the construction method. Finally, the method is applied to Liaoyang east road station of Qingdao metro Line 2, and the results are verified by numerical simulation and monitoring measurement data. The results show that the model is scientific, practical and applicable.