• 생약학회지
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• 제37권4호
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• pp.266-271
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• 2006

Sophorae Radix, the dried roots of Sophora flavescens Aiton (Leguminosae), has been used in oriental traditional medicine for treatment of skin and mucosal ulcers, sores, gastrointestinal hemorrhage, diarrhea, inflammation and arrhythmia. Present study was carried out for the gastroprotective effect of trifolirhizin from Sophora flavescens. This reports were evaluated antibacterial activity against Helicobacter pylori and HCl ethanol-induced gastric lesion in rats and showed the significant effectiveness. In pylorus ligated rats, the treatments of trifolirhizin showed decrease in the volume of gastric secretion and acid output. Also we evaluated the antibacterial activity against H. pylori treated with methanol extract and trifolirhizin from Sophora flavescens had a equivalent antibacterial activity with ampicillin against H. pylori at the dose of $100{\mu}g/mL$. It may be regarded that the antigastritic effects and antibacterial activity of trifolirhizin from Sophora flavescens are originated from reduction of total acid output identified by gastric secretion reduce, free radical scavenging effects and the antibacterial activity against H. pylori.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2009년도 학술대회
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• pp.99-104
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• 2009

최근 멀티미디어 기술과 가상/증강현실 기술의 발전으로 사용자에게 몰입감 있는 콘텐츠를 제공하는 여러 시스템들이 제안되고 있다. 또한 기존의 시각과 음향효과만으로 이루어진 시스템의 한계를 넘어서 실제와 같은 느낌을 전달할 수 있는 햅틱기술을 적용하여 보다 몰입감있는 체험형 실감책들이 고안되고 있다. 본 논문은 과학교과서를 중심으로 과학적 이론을 보다 효과적으로 가르치고 배우기 위해 필요한 다양한 촉감(Haptic)을 분류하고, 이를 실감책에 적용하여 책이 담고 있는 주요 내용 또는 삽화와 관련된 다양한 멀티미디어 콘텐츠를 가상/증강환경에서 시청각정보와 함께 촉각콘텐츠를 독자에게 제공함으로써 보고, 듣고 만질 수 있는 적극적인 촉감 상호작용이 가능한 실감책 ('Sil-Gam' Book) 시스템의 기본 프레임워크를 제시한다. 제시된 실감책은 크게 세 부분으로 구성된다. 첫째, 실감책을 읽고 있는 사용자의 손가락의 위치, 시선과 같은 사용자의 움직임을 추적하고 책의 크기, 페이지 등을 인식하는 센서가 부착된 센싱 부; 둘째, 장비에 따라 적용 가능한 촉감 속성, 물체의 움직임에 따라 적용할 수 있는 촉감 속성등 다양한 촉감콘텐츠의 속성을 저작하고 편집하는 소프트웨어 부; 마지막으로 사용자에게 저작된 실감 콘텐츠를 사용자가 쉽고 직관적으로 체험하게 하기 위한 디스플레이부로 구성된다. 여기서 디스플레이 부는 세부적으로 시청각 콘텐츠를 전달하는 시청각 디스플레이 부와 역촉감 콘텐츠를 전달하는 역촉감 디스플레이부로 구성된다. 본 논문에서는 또한 실감책 촉감 저작도구를 사용하여 제시할 수 있는 다양한 촉감을 중고등학교 교육과정에서 배우는 과학 이론에 적용하여 과학 실험시 경험할 수 있는 다양한 역/촉감을 전달하는 몇 가지 시나리오를 예시하였다.

• 한국주조공학회지
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• 제30권2호
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• pp.60-65
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• 2010

In this study, we investigate the effects of austempering heat treatment on the processing window and mechanical properties in cast and hot-rolled Fe-0.7 C-2.3 Si-0.3 Mn steel. Each specimens were austenitised at $900^{\circ}C$ for 7 min, and austempered at $260^{\circ}C,\;320^{\circ}C$, and $380^{\circ}C$ for the various periods of time from 2 min to 240 min. After heat treatment, the evaluation of stage I and stage II as performed by optical metallography, XRD, hardness test. Both cast and hot rolled specimens had similar processing window. So grain size effect is not important to the austempered high carbon high silicon cast steel. When the austempering temperature was $260^{\circ}C$, the microstructure consisted of the lower ausferrite while the upper ausferrite structure was formed at $380^{\circ}C$. As the austempering temperature increases from 260 to $380^{\circ}C$, the strength and hardness decreased, elongaton and volume fraction of austenite increased. In addition, there was no change of mechanical properties between cast and hot-rolled specimens.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.353-357
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• 1997

We have developed a prototype of a module-based patient monitor. In this paper, we describe the design methodology and specifications of the developed module-based patient monitors. The monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases, each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and $SpO_2$ with plethysmograph.

• Elastomers and Composites
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• 제46권2호
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• pp.132-137
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• 2011

본 연구는 H-NBR 함량 변화에 따른 H-NBR/NBR 블렌드의 열노화 거동에 대하여 살펴보았다. 이 때 가교제로는 dicumyl peroxide와 황 혼합물을 사용하였으며, 열노화에 따른 H-NBR/NBR 블렌드의 인장강도, 파괴신율, 경도 그리고 내마모성의 변화를 살펴보았다. H-NBR을 첨가함에 따라 인장강도는 증가하였으나 내마모성은 감소하는 현상을 나타내었다. 파괴신율과 경도는 H-NBR의 영향을 받지 않았다. 노화가 진행된 모든 시편은 초기 시편보다 낮은 인장강도, 파괴신율, 경도를 나타내었다. 그러나 H-NBR의 함량이 증가함에 따라 이러한 물성저하 속도가 감소함을 알 수 있었다. 즉 H-NBR 첨가에의해 열노화 특성이 향상됨을 알 수 있었다. 모든 NBR/H-NBR 블렌드는 노화시간이 증가함에 따라 내마모성이 감소하였으며, H-NBR을 첨가한 경우 내마모성의 저하가 상대적으로 낮음을 알 수 있었다.

• 한국약용작물학회지
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• 제24권1호
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• pp.47-54
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• 2016

Background : A new extraction method-heated ultrasonic extraction was qualitatively and quantitatively analyzed for the extraction of major ginsenosides from ginseng extract; this new high-performance liquid chromatography (HPLC) method was compared with the official extraction method of Korean industrial standards and standard for health functional food. Methods and Results : Ginsenoside compounds were analyzed for 35 minutes by the new HPLC analysis method using a Halo$^{(R)}$ RP-Amide column. The new HPLC analysis method was validated by the measurement of intra-day and inter-day precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) of each ginsenoside. The correlation coefficients (r2) for the calibration curves of the ginsenoside compounds were over 0.9997 in terms of linearity. The heated ultrasonic extraction method using ultrasonication for 30 minutes at $50^{\circ}C$ yielded higher amount of ginsenosides than the extraction method of the Korean industrial standards owing to the enhancement of extraction efficiency. Conclusions : Compared to the other extraction methods, the heated ultrasonic extraction method yielded a higher amount of ginsenoside Rb1 than Rg1 index compounds for the quality evaluation of ginseng roots.

• Bulletin of the Korean Chemical Society
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• 제32권2호
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• pp.613-619
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• 2011

Colloidal silver nanoparticles (AgNPs) have been commercialized as the typically stabilized form via the addition of a variety of surfactants or polymers. Herein, to examine the effects of stabilizing AgNPs in suspension, we modified the surface of bare AgNPs with four type of surfactants (NaDDBS, SDS, TW80, CTAB) and polymers (PVP, PAA, PAH, CMC). The modified AgNPs was applied to compare suspension stability and nanotoxicity test using Escherichia coli (E. coli) as a model organism. Modification of AgNPs surface using chemical stabilizer may be not related with molecular weight, but chemical structure such as ionic state and functional group of stabilizer. In this study, it is noteworthy that AgNPs modified with a cationic stabilizer (CTAB, PAH) were importantly toxic to E. coli, rather than anionic stabilizers (NaDDBS, SDS). Comparing similar anionic stabilizer, i.e., NaDDBS and SDS, the result showed that lipophilicity of chemical structure can affect on E. coli, because NaDDBS, which contains a lipophilic benzene ring, accelerated the cytotoxicity of AgNPs. Interestingly, none of the stabilizers tested, including biocompatible nonionic stabilizers (i.e., TW80 and cellulose) caused a reduction in AgNP toxicity. This showed that toxicity of AgNPs cannot be reduced using stabilizers.

• 지구물리
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• 제3권1호
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• pp.13-24
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• 2000

제주도 내의 13개의 수준점에서 GPS를 측정하였으며, 이에 의한 GPS/Levelling 지오이드와 PNU95 지오이드를 비교, 분석하여 보았다. GPS의 측정결과 각. 수준점의 타원체 높이를 ${\pm}3\;cm$ 이내의 정밀도로 측정하였다. 계산된 GPS/Levelling 지오이드는 제주도의 지형 변화를 잘 나타내고 있으며, 제주도에서 지오이드와 지형의 상관식은 다음과 같다. $$N\;=\;0.001082\;{\times}\;h\;+\;25.458\;{\pm}\;0.227\;s.d.$$ 계산된 GPS/Levelling 지오이드와 PNU95 지오이드는 잘 일치하고 있으며 두 지오이드의 RMS 차이는 0.14 m이다.

• 대한족부족관절학회지
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• 제20권3호
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• pp.131-134
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• 2016

Purpose: This study aimed to evaluate the outcomes, including the complications, of open reduction and internal fixation using a headless cannulated compression screw for a fifth metatarsal base fracture. Materials and Methods: We retrospectively investigated 11 patients with 5th metatarsal base fracture who were treated with a headless cannulated compression screw. The mean follow-up period was 13 months (8~15 months), and the mean age was 46.5 years (21~70 years). We analyzed the patients' sex, age, time to union, amount of fracture displacement, and complications. The American Orthopaedic Foot and Ankle Society (AOFAS) midfoot score was used for clinical assessment. Results: The average amount of displacement decreased significantly from 3.4 mm (2.1~5.2 mm), preoperatively, to 0.4 mm (0~1.3 mm), postoperatively (p<0.001). The average bone union time was 54.1 days (41~68 days). There were no complications, such as a metal failure, irritation, and loss of a reduction. The mean AOFAS midfoot score was 97.7 (90~100) at 6 months, postoperatively. Conclusion: We suggest that a headless cannulated compression screw for 5th metatarsal base fracture is a useful and alternative method for a firm fixation without complications.

• 한국정밀공학회지
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• 제25권4호
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• pp.134-139
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• 2008

A spirally arrayed nano-pattern is designed as a model pattern for the next generation optical storage media. The pattern consists off types of embossed rectangular dot, which are 50nm, 100nm, 150nm and 200nm in length and 50nm in width. The height of the dot is designed to be 50nm. The pitch of the spiral track of the pattern is 100nm. A ER(Electron resist) master for this pattern is fabricated by e-beam lithography process. The ER is first spin-coated to be 50nm thick on a Si wafer and then the model pattern is written on the coated ER layer by e-beam. After developing this pattern written wafer in the solution, a ER pattern master is fabricated. The most conventional e-beam machine can write patterns in orthogonal way, so we made our own pattern generator which can write the pattern in circular or spiral way. This program generates the patterns to be compatible with the e-beam machine from Raith(Raith 150). To fabricate 50nm pattern master precisely, a series of experiments were done including the design compensation for the pattern size, optimization of the dose, acceleration voltage, aperture size and developing. Through these experiments, we conclude that the higher accelerating voltages and smaller aperture size are better for mastering the nano pattern which is in order of 50nm. With the optimized e-beam lithography process, a spiral arrayed 50nm pattern master adopting PMMA resist was fabricated to have dimensional accuracy over 95% compared to the designed. Using this pattern master, a metal pattern stamp will be fabricated by Ni electro plating for injection molding of the patterned plastic substrate.