• Korean Journal of Materials Research
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• v.28 no.3
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• pp.166-173
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• 2018

Molybdenum (Mo) is one of the representative refractory metals for its high melting point, superior thermal conductivity, low density and low thermal expansion coefficient. However, due to its high melting point, it is necessary for Mo products to be fabricated at a high sintering temperature of over $1800-2000^{\circ}C$. Because this process is expensive and inefficient, studies to improve sintering property of Mo have been researched actively. In this study, we fabricated Mo nanopowders to lower the sintering temperature of Mo and tried to consolidate the Mo nanopowders through ultra high pressure compaction. We first fabricated Mo nanopowders by a mechano-chemical process to increase the specific surface area of the Mo powders. This process includes a high-energy ball milling step and a reduction step in a hydrogen atmosphere. We compacted the Mo nanopowders with ultra high pressure by magnetic pulsed compaction (MPC) before pressureless sintering. Through this process, we were able to improve the green density of the Mo compacts by more than 20 % and fabricate a high density Mo sintered body with more than a 95 % sintered density at relatively low temperature.

• Journal of Korea Game Society
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• v.10 no.5
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• pp.65-73
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• 2010

In this paper, we developed the device for an interactive game interface using bio signals which were able to recognize user's motion intention using EMG signals and it was applied to the games which need the information of the muscle motion directions. The module for acquiring EMG signals consists of 4-Ch, wrist-motions were defined as up, right, down and left state. The user's intent was recognized through thresholding and comparing signals of each channel. The classification result of the motion directions could control the arrow keys on the keyboard of PC and it was applied on the various games. This proposed game device can be expected to induce an effective exercise with an interesting and enjoyment, and it can use both self-developed or commercial games.

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.1
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• pp.138-152
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• 2010

This study investigates the actual hospital-clothes consumption experience of consumers according to gender and age. An all age survey was conducted among male and female ex-patients in Korea nationally. From data collected during April and May 2009, a total of 513 responses were analyzed using descriptive statistics, chi-square analysis, two-way ANOVA, and MANOVA using SPSS 10.1.4. The results are as follows. The hospitalization ratio was higher in the male group than in the female group and increased with age. Many hospitalizations were taken to the department of orthopedics, internal treatment, obstetrics and gynecology, and surgery. The satisfaction with patient gowns was low regarding size, fabric touch, color and pattern, Psychological comfort, and holistic satisfaction, Specifically, the stiffness of the fabric, cheerless colors, and the limited number of sizes were the main complaints; size dissatisfaction was expressed strongly by females. About 35% of respondents showed a positive attitude to wear premium patient gowns. Various medical supplies were used and different items were utilized according to gender and age of patients. Uncomfortableness of medical supplies were highly related to laundry and fabric touch.

• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.121-125
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• 2007

Background and Purpose : The purpose of this study was done to investigate what kinds of statistical techniques have been used to analyze data from oriental medicine research Methods : 135 original articles which used statistical techniques in their data analysis were selected from the articles published in The Journal of Korea Institute of Oriental Medicine(JKIOM) between 1995 to 2007. Results : Among 135 articles, 59 articles used descriptive statistics while 76 articles used inferential statistics for data analysis. For that 76 articles, two-sample t-test(33 articles), analysis of variance(29 articles), regression(9 articles), chi-square test(5 articles), nonparametic test(4 articles), Fisher's exact test(3 articles), and other test(9 articles) were chosen to analyze the data. SAS and SPSS statistical softwares(82.50%) were mostly used to analyze the data. Nonparametic tests were used to 4 articles(6.97%) of 67 articles and parametic tests were used to 63 articles(93.03%) of 67 articles. Among 29 articles used analysis of variance, duncan(8 articles), dunnet(4 articles), bonferroni(4 articles), turkey(3 articles), scheff(1 article) were used to do multiple comparison. 9 articles did not carry out the multiple comparison. Conclusions : It was found that the frequencies of statistical package used and statistical analysis used were not much by now. High level statistical analyses were not used most for oriental medicine research.

• Journal of Korean Neurosurgical Society
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• v.50 no.6
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• pp.481-485
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• 2011

Objective : The purpose of this study is to investigate serial changes of hypoxia-inducible factor $1{\alpha}$ (HIF-$1{\alpha}$), as a key regulator of hypoxic ischemia, and apoptosis of hippocampus induced by bilateral carotid arteries occlusion (BCAO) in rats. Methods : Adult male Wistar rats were subjected to the permanent BCAO. The time points studied were 1, 2, 4, 8, and 12 weeks after occlusions, with n=6 animals subjected to BCAO, and n=2 to sham operation at each time point, and brains were fixed by intracardiac perfusion fixation with 4% neutral-buffered praraformaldehyde for brain section preparation. Immunohistochemistry (IHC), western blot and terminal uridine deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay were performed to evaluate HIF-$1{\alpha}$ expression and apoptosis. Results : In IHC and western blot, HIF-$1{\alpha}$ levels were found to reach the peak at the 2nd week in the hippocampus, while apoptotic neurons, in TUNEL assay, were maximal at the 4th week in the hippocampus, especially in the cornu ammonis 1 (CA1) region. HIF-$1{\alpha}$ levels and apoptosis were found to fluctuate during the time course. Conclusion : This study showed that BCAO induces acute ischemic responses for about 4 weeks then chronic ischemia in the hippocampus. These in vivo data are the first to show the temporal sequence of apoptosis and HIF-$1{\alpha}$ expression.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.10a
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• pp.629-638
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• 2005

본 연구대상 사면은 연장이 300m이고 최대 사면높이가 80m에 달하는 대절토 사면으로 서 총 11 소단으로 이루어져 있으며, 전 사면에 걸쳐 Soil Nail 공법으로 보강이 되어있다. 사면 상단부에 설치된 2개의 경사계를 이용하여 주기적으로 사면의 수평방향 변위 계측을 실시하던 중, 사면 하부의 소단 굴착과정에서 상대적으로 급격한 사변경사 방향의 수평변위가 발생한 것을 확인하였다. 본 연구에서는 사면의 수평방향 변위 계측결과 분석 및 대상 사면에 대한 수치해석을 통하여 사면의 안정성 여부를 판단하고자 하였으며, 굴착단계별 수평방향 변위량 및 변위 양상을 분석함으로써 급격히 증가한 변위의 원인을 파악하였다. 수치해석을 통해 나타난 사면 굴착 단계에 따른 사면 토체의 소성영역을 도시한 결과, 사면 전체에 걸쳐 대규모 파괴면이 나타났으며 파괴활동면이 Soil Nail 로 보강된 영역의 바깥쪽에 위치하여 사면 안정성 확보를 위한 대책방안이 수립되어야 할 것으로 판단되었다. 또한 보다 자세한 원인 규명을 위한 확인 시추조사를 실시하여 하부 지층 특성을 파악하였으며, 하부에 풍화가 심하고 절리 및 균열이 심한 파쇄구간이 분포하고 있음이 확인되었다. 연구 대상 사면의 변위 계측 결과, 수치해석 결과, 확인 시추 조사 결과 및 예상되는 사면 활동의 규모 등을 고려할 때 사변의 안정성 확보를 위한 대책방안이 수립되어야 하며, 본 사면은 억지말뚝과 Ahchor 공법 적용이 가장 적절할 것으로 판단되었다.

• The Journal of Korean Medicine
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• v.30 no.3
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• pp.70-78
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• 2009

Objectives : This study was aimed at examining the effects of the application of EA (electroacupuncture) at GV20 and LI4 in the early cerebral ischemia on the size of cerebral infarction, COX-2 and IL-6. Methods : For this experiment, 21, six-week-old male S-D (Sprague - Dawley) rats weighting 160g to 200g were selected and randomly classified into 3 groups, seven rats in each group. Brain ischemia was simulated using a modified Koizumi method which was performed on each rat. In the GV20 group, the GV20 of the SD rats was stimulated for thirty minutes with acupunctural electrode low frequency stimulator five hours after inducement of ischemia. For the LI4 group, the LI4 was stimulated as above, while for the Ischemia group, no stimulation was applied. Twenty-four hours after the experiment, stained cerebral tissues were examined and an immuno-histological test was done to examine inflammatory reaction Results : Out of the three groups, the LI4 group showed the smallest size of cerebral infarction and the Ischemia group showed the highest COX-2 (cyclooxygenase-2) expression value in the cortex of the cerebrum. In addition, the LI4 group showed the lowest COX-2 expression value in unknown putamen out of the three groups. Conclusions : We infer that EA, applied at LI4 and GV20 in early ischemia, is effective in delaying the expression of IL-6 (interleukin-6) and COX-2, the inflammatory agents manifested from stroke. In addition, application at LI4, rather than GV20, can lower the expression value of the inflammatory agents. Further, EA can be an effective way to block early inflammatory reaction in stroke.

• Archives of Plastic Surgery
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• v.38 no.6
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• pp.755-760
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• 2011

Purpose: Correction of cleft lip nose deformity (CLND) in adulthood is different from one in childhood. Usually correction of CLND is final surgery for adult patient who has cleft lip, so many things have to be considered for correction. Of course, it is different from common rhinoplasty, either. The adult patients can be corrected by complete rhinoplasty with various techniques. To recognize how rhinoplasty techniques was used for correction of CLND, authors analyzed detailed techniques which were selected in the adult patients for 10 years and reviewed comprehensive operation. Methods: A retrospective review was conducted involving 64 patients with CLND who underwent surgery and aged after 14 years at operation between 2001 and 2010. Detailed techniques were investigated by medical record review and classified according to incision, septoplasty, osteotomies, correction of vault, tip plasty and etc. Results: Except one, all patients were performed open rhinoplasty. 49 patients were performed septoplasty. 33 patients were performed complete rhinoplasty with osteotomies. Hump nose correction was performed for 10 patients. Dorsal augmentation was performed for 8 patients. And all patients were performed tip plasty. Tip plasty using suture technique was performed for 58 patients and graft was performed for 48 patients. Conclusion: Correction of CLND in adult is one of the most challenging and varied operation of plastic surgery. In this study, the majority of patients were performed complicated and delicated procedures. It seems to be because patient's demand level has been elevated and rhinoplasty procedures have been advanced. This study may help to planning of CLND correction.

• Archives of Plastic Surgery
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• v.32 no.2
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• pp.214-218
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• 2005

The anatomy and distribution of the superficial temporal vessels are known to follow regular patterns, with few exceptions in previous studies. But these previous studies of the anatomy and distribution of the superficial temporal vessels were based, only on the cadaver studies. Authors evaluated the anatomy of these vessels in the operative field of the living body from December 1997 to June 2001, The superficial temporal vessels were surgically exposed from the zygomatic arch extending to the superior temporal line through a preauricular incision in 18 patients(20 cases), who underwent reconstructive surgery using these vessels in the operative field. The authors measured and analyzed; the distribution, branching and diameters of the superficial temporal vessels. The results were obtained as follows; 1.In 19 cases, STV(superficial temporal vein) runs posterior to STA(superficial temporal artery) at the upper border of the zygomatic arch. 2. There was no frontal or parietal branches in 2 cases and vena comitante existed along with STA in one case. 3. The external diameter of STA and STV was measured at the lower border of the zygomatic arch. The external diameter of STA ranged from 1.5 mm to 3.0 mm(average 2.1 mm) and those of STV ranged from 1.3 mm to 3.5 mm (average 2.0 mm). This study can be helpful in the reconstructive surgery using the superficial temporal vessels, for the results of our study are based on the true anatomy of the living body.

• Journal of Microbiology and Biotechnology
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• v.11 no.6
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• pp.1077-1086
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• 2001

The sprA and sprB gene encoding chymotrypsin-like proteases Streptomyces griseus protease A (SGPA) and Streptomyces griseus protease B (SGPB) and the sprT gene that encodes Streptomyces griseus trypsin (SGT) were cloned from Streptomyces griseus ATCC10137 and overexpressed in Streptomyces lividans TK24 as a heterologous host. The chymotrypsin activity of tole culture broth measured with the artificial chromogenic substrate , N-succinyl-ala-ala-pro-phe-p-nitroanilide, was 10, 14 and 14 units/mg in the transformants haboring the sprA, sprB and sprD genes, respectively. The growth of S. lividans reached the maximum cell mass after 4 days of culture, yet SGPA and SGPD production started in the stationary phase of cell growth and kept increasing for up to 10 days of culture in an R2YE medium. The trypsin activity of the culture broth measured with the artificial chromogenic substrate , N-${\alpha}$-benzoyl-DL- arginine-p-nitroanilide , was 16 units/mg and SGT production started in the stationary phase of cell growth and kept increasing for up to 10 days of culture in an R2YE medium. The introduction of the sprA gene into S, lividans TK24 triggered the biosynthesis of pigmented antibiotics, actinorhodin and undecylprodigiosin, and induced significant morphological changes in the colonies in Benedict, R2YE, and R1R2 media. In addition, the introduction of the sprT gene also induced morphological changes in the colony shape without affecting the antibiotic production, thereby implying that certain proteases would appear to play very important and specific roles in secondary-metabolites formation and morphological differentiation in Streptomyces.