• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.12 no.1
• /
• pp.130-136
• /
• 2008

This paper describes a low-power high-performance analog front-end block for $UHF(860{\sim}960MHz)$ band RFID tag chips. It satisfies ISO/IEC 18000-6 type C(EPCgolbal class1. generation2.) and includes a memory block for test. For reducing power consumption, it operates with a internally generated power supply of 1V. An ASK demodulator using a current-mode schmitt trigger is proposed and designed. The proposed demodulator has an error rate as low as 0.014%. It is designed using a 0.18um CMOS technology. The simulation results show that the designed circuit can operate properly with an input as low as $0.2V_{peak}$ and consumes $2.63{\mu}A$. The chip size is $0.12mm^2$

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2009.10a
• /
• pp.397-400
• /
• 2009

This paper describes ASIC design of Multimedia application SoC platform based RISC processor with BTB(Branch Target Buffer). For performance enhancement of platform, we use a simple branch prediction scheme, BTB structure, that stores a target address for branch instruction to remove pipeline harzard. Also, the platform includes a number of peripheral such as VGA controller, AC97 controller, UART controller, SRAM interface and Debug interface. The platform is designed and verified on a Xilinx VERTEX-4 FPGA using a number of test programs for functional tests and timing constraints. Finally, the platform is implemented into a single ASIC chip which can be operated at 100MHz clock frequency using the Chartered 0.18um process. As a result of performance estimation, the proposed platform shows about 5~9% performance improvement in comparison with the previous SoC Platform.

• KIPS Transactions on Computer and Communication Systems
• /
• v.8 no.11
• /
• pp.251-262
• /
• 2019

In this paper, we propose a simulator that provides various algorithms of RBF networks on neuromorphic chips. To develop algorithms based on neuromorphic chips, the disadvantages of using simulators are that it is difficult to test various types of algorithms, although time is fast. This proposed simulator can simulate four times more types of network architecture than existing simulators, and it provides an additional a two-layer structure algorithm in particular, unlike RBF networks provided by existing simulators. This two-layer architecture algorithm is configured to be utilized for multiple input data and compared to the existing RBF for performance analysis and validation of utilization. The analysis showed that the two-layer structure algorithm was more accurate than the existing RBF networks.

• Asian-Australasian Journal of Animal Sciences
• /
• v.32 no.5
• /
• pp.607-613
• /
• 2019

Objective: Intramuscular fat (IMF) content plays an important role in meat quality. Identification of single nucleotide polymorphisms (SNPs) and genes related to pig IMF, especially using pig populations with high IMF content variation, can help to establish novel molecular breeding tools for optimizing IMF in pork and unveil the mechanisms that underlie fat metabolism. Methods: We collected muscle samples of 453 Chinese Lulai black pigs, measured IMF content by Soxhlet petroleum-ether extraction method, and genotyped genome-wide SNPs using GeneSeek Genomic Profiler Porcine HD BeadChip. Then a genome-wide association study was performed using a linear mixed model implemented in the GEMMA software. Results: A total of 43 SNPs were identified to be significantly associated with IMF content by the cutoff p<0.001. Among these significant SNPs, the greatest number of SNPs (n = 19) were detected on Chr.9, and two linkage disequilibrium blocks were formed among them. Additionally, 17 significant SNPs are mapped to previously reported quantitative trait loci (QTLs) of IMF and confirmed previous QTLs studies. Forty-two annotated genes centering these significant SNPs were obtained from Ensembl database. Overrepresentation test of pathways and gene ontology (GO) terms revealed some enriched reactome pathways and GO terms, which mainly involved regulation of basic material transport, energy metabolic process and signaling pathway. Conclusion: These findings improve our understanding of the genetic architecture of IMF content in pork and facilitate the follow-up study of fine-mapping genes that influence fat deposition in muscle.

• Tuberculosis and Respiratory Diseases
• /
• v.82 no.2
• /
• pp.126-132
• /
• 2019

Background: The development of lung cancer results from the interaction between genetic mutations and dynamic epigenetic alterations, although the exact mechanisms are not completely understood. Changes in DNA methylation may be a promising biomarker for early detection and prognosis of lung cancer. We evaluated the serial changes in genome-wide DNA methylation patterns in blood samples of lung cancer patients. Methods: Blood samples were obtained for three consecutive years from three patients (2 years before, 1 year before, and after lung cancer detection) and from three control subjects (without lung cancer). We used the MethylationEPIC BeadChip method, which covers the 850,000 bp cytosine-phosphate-guanine (CpG) site, to conduct an epigenome-wide analysis. Significant differentially methylated regions (DMRs) were identified using p-values <0.05 in a correlation test identifying serial methylation changes and serial increase or decrease in ${\beta}$ value above 0.1 for three consecutive years. Results: We found three significant CpG sites with differentially methylated ${\beta}$ values and 7,105 CpG sites with significant correlation from control patients without lung cancer. However, there were no significant DMRs. In contrast, we found 11 significant CpG sites with differentially methylated ${\beta}$ values and 10,562 CpG sites with significant correlation from patients with lung cancer. There were two significant DMRs: cg21126229 (RNF212) and cg27098574 (BCAR1). Conclusion: This study revealed DNA methylation changes that might be implicated in lung cancer development. The DNA methylation changes may be the possible candidate target regions for the early detection and prevention of lung cancer.

• Korean Journal of Metals and Materials
• /
• v.47 no.1
• /
• pp.26-31
• /
• 2009

The effects of $Ar/O_2$ ion-beam pre-treatment conditions on the interfacial adhesion energy of sputterdeposited Cu thin film to FR-4 substrate were systematically investigated in order to understand the interfacial bonding mechanism for practical application to advanced chip-in-substrate package systems. Measured peel strength increases from $45.8{\pm}5.7g/mm$ to $61.3{\pm}2.4g/mm$ by $Ar/O_2$ ion-beam pre-treatment with anode voltage of 64 V. Interfacial bonding mechanism between sputter-deposited Cu film and FR-4 substrate seems to be dominated by chemical bonding effect rather than mechanical interlocking effect. It is found that chemical bonding intensity between carbon and oxygen at FR-4 surface increases due to $Ar/O_2$ ion-beam pretreatment, which seems to be related to the strong adhesion energy between sputter-deposited Cu film and FR-4 substrate.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.10 no.3
• /
• pp.321-326
• /
• 2022

In this study, cogeneration power plants that use biomass as a raw material to convert them into energy have recently received a lot of attention worldwide and are gradually increasing in South Korea. Therefore, in order to confirm the possibility of using the generated floor material as a fine aggregate for concrete, properties and stability evaluation experiments were performed. Compared to standard sand, the compressive strength of wood chip aggregate was improved by 11 % to 111 %, the length change rate was 89 %, and the waste processing test results met all criteria for hazardous substances. All of these are satisfied, and it is judged that the floor materials by the cogeneration power plant can be used as a fine aggregate for concrete.

• Journal of Animal Reproduction and Biotechnology
• /
• v.38 no.1
• /
• pp.32-37
• /
• 2023

This study has evaluated the genomic estimated breeding value (GEBV) of the commercial Hanwoo population using the genomic best linear unbiased prediction (GBLUP) method and genomic information. Furthermore, it analyzed the accuracy and realized accuracy of the GEBV. 1,740 heads of the Hanwoo population which were analyzed using a single nucleotide polymorphism (SNP) Chip has selected as the test population. For carcass weight (CWT), eye muscle area (EMA), back fat thickness (BFT), and marbling score (MS), the mean GEBVs estimated using the GBLUP method were 3.819, 0.740, -0.248, and 0.041, respectively and the accuracy of each trait was 0.743, 0.728, 0.737, and 0.765, respectively. The accuracy of the breeding value was affected by heritability. The accuracy was estimated to be low in EMA with low heritability and high in MS with high heritability. Realized accuracy values of 0.522, 0.404, 0.444, and 0.539 for CWT, EMA, BFT, and MS, respectively, showing the same pattern as the accuracy value. The results of this study suggest that the breeding value of each individual can be estimated with higher accuracy by estimating the GEBV using the genomic information of 18,499 reference populations. If this method is used and applied to individual selection in a commercial Hanwoo population, more precise and economical individual selection is possible. In addition, continuous verification of the GBLUP model and establishment of a reference population suitable for commercial Hanwoo populations in Korea will enable a more accurate evaluation of individuals.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.30 no.2
• /
• pp.121-130
• /
• 2014

Purpose: To assess the surface profile of dentinal wall, dentin chips and smear layer during the canal shaping with rotary (ProTaper) and ProFile and reciprocating (WaveOne) nickel-titanium file. Materials and Methods: Sixty human extracted mandibular premolars and incisors with single canals were randomly selected. Three experimental groups (n = 20) were instrumented with ProTaper (F2), ProFile (25/.06), WaveOne (25/.08) with irrigation of 2.5% NaOCl. The dentin chips were collected from flute of file during each canal preparation. After canal preparation, roots were grinded and each group was divided into two subgroups (n = 10) for surface profile and smear layer of dentinal wall of shaped root canal. Each specimen was observed under scanning electron microscope for evaluating size of dentin chips, root canal surface recessions and smear layer. Scores of Smear layer were statistically analyzed using Kruskal Wallis test and Mann Whitney test at P = 0.05 level. Results: The size of dentin chips from ProFile, ProTaper and WaveOne was up to $7{\mu}m$, $6.5{\mu}m$, and$4{\mu}m$, respectively. In the surface profile, the width of surface irregularity was measured and Profile, ProTaper and WaveOne was up to $150{\mu}m$, $70{\mu}m$, and $80{\mu}m$, respectively. Completely cleaned root canals were not found. In the middle and apical third of the canals, WaveOne group showed higher smear layer score than ProFile and ProTaper groups (P < 0.05). Conclusion: Within limits of this study, reciprocating motion WaveOne group was not significant difference of shaping ability with the full-sequence ProFile and ProTaper systems except canal clearness of middle and apical third of root canal. When using WaveOne to shaping root canal, thorough root canal irrigation is recommended.

• Journal of the Korean Wood Science and Technology
• /
• v.36 no.1
• /
• pp.88-101
• /
• 2008

The aim of this study was to attempt the efficacy of antifungal activity of the wood extracts against Botrytis grey mold. Wood chip derived from Quercus mongolica was obtain from steam explosion process and extracted by hot water and methanol and ethanol. The conidial germination was maximum growth with the application temperature for 20 and $25^{\circ}C$. In pH test, we observed the maximum growth in pH 5.0 and 7.0. Antifungal activity was the best in the hot water extractives against Botrytis cinerea. The separation of the antifungal substances was performed using a silica-gel column (n-hexane : chloroform : ethyl acetate : formic acid = 12 : 17 : 8 : 0.2, v/v/v/v), TLC and UV-Spectrophotometer, and isolated 6 fraction group. The result of antifungal activity in 6 fraction group, fraction group I and fraction group II were the highest antifungal activity against grey mold with the present study. Three peaks in fraction group I and II were detected by HPLC and this compounds were suppose to effective of antifungal activity.