• 제목/요약/키워드: Chip Flow

검색결과 315건 처리시간 0.023초

Measurement of cell aggregation characteristics by analysis of laser-backscattering in a microfluidic rheometry

  • Shin, Se-Hyun;Hou, J.X.;Suh, Jang-Soo
    • Korea-Australia Rheology Journal
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    • 제19권2호
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    • pp.61-66
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    • 2007
  • The aggregation characteristics of red blood cells (RBCs) are known as important factors in the microvascular flow system, and increased RBC aggregation has been observed in various pathological diseases, such as thrombosis and myocardial infarction. This paper describes a simple microfluidic device for measuring the RBC aggregation by integrating a microfluidic slit rheometry and laser-backscattering technique. While a decreasing-pressure mechanism was applied to the microfluidic rheometry, a syllectogram (the light intensity versus time) showed an initial increase and a peak caused by the high shear stress-induced disaggregation, immediately followed by a decrease in the light intensity due to RBC aggregation. The critical shear stress (CST) corresponding to the peak intensity was examined as a new index of the RBC aggregation characteristics. The CST of RBCs increased with increasing aggregation-dominating protein (fibrinogen) in the blood plasma. The essential feature of this design was the combination of the rheometric-optic characterization of RBC aggregation with a microfluidic chip, which may potentially allow cell aggregation measurements to be easily carried out in a clinical setting.

Micro-LIF measurement of microchannel flow

  • Kim Kyung Chun;Yoon Sang Youl
    • 한국가시화정보학회:학술대회논문집
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    • 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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    • pp.65-74
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    • 2004
  • Measurement of concentration distributions of suspended particles in a micro-channel is out of the most crucial necessities in the area of Lab-on-a-chip to be used for various bio-chemical applications. One most feasible way to measure the concentration field in the micro-channel is using micro-LIF(Laser Induced Fluorescence) method. However, an accurate concentration field at a given cross plane in a micro-channel has not been successfully achieved so far due to various limitations in the light illumination and fluorescence signal detection. The present study demonstrates a novel method to provide an ultra thin laser sheet beam having five(5) microns thickness by use of a micro focus laser line generator. The laser sheet beam illuminates an exact plane of concentration measurement field to increase the signal to noise ratio and considerably reduce the depth uncertainty. Nile Blue A was used as fluorescent dye for the present LIF measurement. The enhancement of the fluorescent intensity signals was performed by a solvent mixture of water $(95\%)$ and ethanol (EtOH)/methanol (MeOH) $(5\%)$ mixture. To reduce the rms errors resulted from the CCD electronic noise and other sources, an expansion of grid size was attempted from $1\times1\;to\;3\times3\;or\;5\times5$ pixel data windows and the pertinent signal-to-noise level has been noticeably increased accordingly.

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REID 시스템의 신뢰성 향상에 관한 연구 (A Study on the Reliability Improvement of RFID System)

  • 함정기;이청진;권오흥
    • 디지털콘텐츠학회 논문지
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    • 제7권3호
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    • pp.169-174
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    • 2006
  • RFID는 각종 서비스 산업은 물론 물류, 산업 현장, 제조 공장과 물품의 흐름이 있는 곳이면 어디에서나 적용이 가능하여 사회 여러 분야로부터 큰 관심을 받고 있다. 하지만 현재 900Mhz 대역의 RFID에서 사용하는 ISO/IEC 18000-6의 프로토콜에서는 에러검출을 위한 CRC16만을 사용하여, 에러정정능력을 갖추지 못해 그 신뢰성이 떨어질 것으로 여겨진다. 본 논문에서는 이러한 RFID 시스템의 신뢰성 향상을 위해 Reader에서 Tag로의 명령어 및 데이터 전송 시에 콘벌루션 부호를 적용하여 시스템의 신뢰성 향상을 목적으로 하며, 이런한 방식을 적용했을 때와 적용하지 않았을 때의 에러율을 측정 비교하였다.

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프랜차이즈산업에서의 RFID 적용 방법에 대한 연구 (A Study on RFID Application Method in Franchise Business)

  • 임재석;최원용
    • 대한안전경영과학회지
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    • 제10권4호
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    • pp.189-198
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    • 2008
  • At present, companies write daily work record or use bar-code in order to collect distribution flow data in real time. However, it needs additional works to check the record or read the bar-code with a scanner. In this case, human error could decrease accuracy of data and it would cause problems in reliability. To solve this problem, RFID (Radio Frequency Identification) is introduced in many automatic recognition sector recently. RFID is a technology that identification data is inserted into micro-mini IC chip and recognize, trace, and manage object, animal, or person using wireless frequency. This is being emerged as the core technology in future ubiquitous environment. This study is intended to suggest RFID application method in franchise business. Traceability and visibility of individual product are supplied based on EPCglobal network. It includes DW system which supplies various assessment data about product in supply chain, financial transaction system which is based on product transaction and position information, and RFID middleware which refines and divides product data from RFID tag. With the suggested application methods, individual product's profile data are supplied in real time and it would boost reliability to customer and make effective cooperation with existing operation systems (SCM, CRM, and e-Business) possible.

AC8A-T6 알루미늄 합금재의 절삭가공 특성에 관한 연구 (A Study on the Characteristics of Machining for AC8A-T6 Aluminum Alloy)

  • 최현민;김경우;김우순;김용환;김동현;채왕석
    • 한국공작기계학회:학술대회논문집
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    • 한국공작기계학회 2002년도 추계학술대회 논문집
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    • pp.192-197
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    • 2002
  • In this study, examined the cutting characteristics of alumuminum alloy AC8A-T6 that is used to present car piston materials. And in been holding materials machining empirically escape as result that experiment comparison changing the cutting speed and feed on various condition to choose efficient machining condition. The following results can be summarized from this research. 1. As the cutting speed decreased, principal cutting force and thrust cutting force is increased, and reason that cutting force interacts greatly in the low cutting speed is thought by result by BUE's stabilization. 2. The feed speed and cutting speed increase, friction factor is decrescent and the cause appeared the thrust cutting force is fallen than cutting force relatively because chip flow according to increase of the feed rate is constraint. 3. Though specific cutting resistance grows cutting area and the feed rate are few, the cause was expose that shear angle decreases by rake face of tool gets into negative angle remarkably as wear of a cutting tool or defect part of workpiece is cut. 4. Cutting speed do greatly depth of cut is slow, surface roughness examined closely through an experiment that becomes bad, and know that it can get good surface that process cutting speed because do feed rate by 0.1mm/rev low more than 250m/min to get good surface roughness can.

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ARM-Excalibur를 이용한 H.264/AVC 디코더의 HW/SW 병행 설계 (HW/SW co-design of H.264/AVC Decoder using ARM-Excalibur)

  • 정준모
    • 한국산학기술학회논문지
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    • 제10권7호
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    • pp.1480-1483
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    • 2009
  • 본 논문에서는 H.264 및 AVC 디코더를 ARM-Excalibur를 이용하여 하드웨어(HW:Hardware)와 소프트웨어 (SW:Software)로 병행설계(co-design)하는 방법에 대해서 제안한다. 내장형 프로세서, 메모리, 주변장치 및 논리 회로들을 하나의 칩으로 집적한 SoC(System On-a-Chip)를 하드웨어와 소프트웨어로 분할하여 병행 설계(co-design)하는 방식이 새로운 설계 방법으로 대두되고 있다. 최적화된 분할 방법을 찾는 것이 매우 어렵기 때문에 설계 초기단계에서 빠르게 검증할 필요가 있는데 본 논문에서는 H.264 및 AVC 디코더를 알테라사의 ARM-Excalibur라는 칩을 이용하여 효율적으로 병행 설계하였으며 시스템의 동작속도가 크게 향상되는 것을 확인할 수 있었다.

경사진 전극링을 이용한 고균일도의 미세 솔더범프 형성 (Formation of fine pitch solder bump with high uniformity by the tilted electrode ring)

  • 주철원;이경호;민병규;김성일;이종민;강영일
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2004년도 하계학술대회 논문집 Vol.5 No.1
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    • pp.323-327
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    • 2004
  • The bubble flow from the wafer surface during plating process was studied in this paper. The plating shape in the opening of photoresist becomes gradated shape in the fountain plating system, because bubbles from the wafer surface are difficult to escape from the deep openings, vias. So, we designed the tilted electrode ring contact to get uniform bump height on all over the wafer and evaluated the film uniformity by SEM and ${\alpha}-step$. In ${\alpha}-step$ measurement, film uniformities in the fountain plating system and the tilted electrode ring contact system were ${\pm}16.6%,\;{\pm}4%$ respectively.

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진동절삭을 이용한 고정도 미세가공 (High-precision Micro-machining using Vibration Cutting)

  • 손성민;임한석;안중환
    • 한국정밀공학회지
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    • 제16권3호통권96호
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    • pp.72-77
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    • 1999
  • This paper presents 2-dimensional vibration cutting increases dynamic stiffness of tool support and improves the quality of machined surface in micro-machining. 2-dimensional vibration cutting is generated by two piezo actuators arranged orthogonally. A sine-type voltage is input to one actuator and a phase-shifted sine-type voltage is input the other. Then the vibration device actuates the tool in a 2-D elliptical motion with pulsed cutting force. It is a characteristic of 2-D vibration cutting that some negative thrust force occurs as the direction of friction on a tool rake surface is reversed. It helps not only chip flow smoothly and continuously but also cutting force be reduced. The quality of machined surface by 2-D vibration cutting depends on such parameters as vibration amplitude, frequency, cutting speed, depth of cut, etc. Compared to conventional cutting through tool path simulation and experiments under several conditions, the 2-D vibration cutting is verified to bring forth a great decrease of cutting forces, much better surface roughness and moreover much less burr.

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탄소나노튜브 소재의 정밀 수동소자 적용을 위한 한계 정격전력 용량에 관한 연구 (A Study on the Limited Rate Power Capacity for Applications for Precision Passive Devices Based on Carbon Nanotube Materials)

  • 이선우
    • 한국전기전자재료학회논문지
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    • 제35권3호
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    • pp.269-274
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    • 2022
  • We prepared carbon nanotube (CNT) paper by a vacuum filtration method for the use of a chip-typed resistor as a precision passive device with a constant resistance. Hybrid resistor composed of the CNT resistor with a negative temperature coefficient of resistance (T.C.R) and a metal alloy resistor with a positive T.C.R could lead to a constant resistance, because the resistance increase owing to the temperature increase at the metal alloy and decrease at the CNT could counterbalance each other. The constant resistance for the precision passive devices should be maintained even when a heat was generated by a current flow resulting in resistance change. Performance reliabilities of the CNT resistor for the precision passive device applications such as electrical load limit, environmental load limit, and life limit specified in IEC 60115-1 must be ensured. In this study, therefore, the rated power determination and T.C.R tests of the CNT paper were conducted. -900~-700 ppm/℃ of TCR, 0.1~0.2 A of the carrying current capacity, and 0.0625~0.125 W of the rated power limit were obtained from the CNT paper. Consequently, we confirmed that the application of CNT materials for the precision hybrid passive devices with a metal alloy could result in a better performance reliability with a zero tolerance.

High-density single nucleotide polymorphism chip-based conservation genetic analysis of indigenous pig breeds from Shandong Province, China

  • Wang, Yanping;Zhao, Xueyan;Wang, Cheng;Wang, Wenwen;Zhang, Qin;Wu, Ying;Wang, Jiying
    • Animal Bioscience
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    • 제34권7호
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    • pp.1123-1133
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    • 2021
  • Objective: Shandong indigenous pig breeds are important Chinese pig resources. Their progressive population decline in recent decades has attracted attention towards their conservation. Conservation genetics of these indigenous breeds are essential for developing a conservation and utilization scheme. Methods: A high-density single nucleotide polymorphism (HD-SNP) chip-based comparative analysis of genetic characteristics was performed for seven Shandong indigenous pig breeds in the context of five Western commercial breeds. Results: The results showed that Shandong indigenous pig breeds varied greatly in genetic diversity, effective population size, inbreeding level, and genetic distance with the Western commercial breeds. Specifically, Laiwu and Dapulian displayed low genetic diversity, and had a genetically distant relationship with the Western commercial breeds (average F statistics [FST] value of 0.3226 and 0.2666, respectively). Contrastingly, the other five breeds (Yantai, Licha, Yimeng, Wulain, and Heigai) displayed high genetic diversity within breed and had some extent of mixture pattern with the Western commercial breeds, especially Duroc and Landrace (FST values from 0.1043 to 0.2536). Furthermore, intensive gene flow was discovered among the seven Shandong indigenous breeds, particularly Wulian, Licha, and Heigai, as indicated by the large cluster formed in the principal component analysis scatterplot and small population differentiation (average of 0.1253) among them. Conclusion: Our study advances the understanding of genetic characteristics of Shandong indigenous breeds and provides essential information for developing an appropriate conservation and utilization scheme for these breeds.