• 대한소아치과학회지
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• 제43권1호
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• pp.27-35
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• 2016

본 연구는 전신마취 또는 정주진정 하 치과치료가 주 양육자가 인식하는 환아의 구강 건강과 관련된 삶의 질과 환아 가족의 일상생활에 미치는 영향을 확인하기 위해 시행되었다. 10세 이하의 건강한 환아와 그 환아의 주 양육자를 대상으로 연구가 진행되었다. 환아가 전신마취 또는 정주진정 하 치과치료를 위해 내원한 당일, 치료 시작 전에 환아의 주 양육자가 설문지를 작성하고, 치료 후 6개월 이내에 동일한 주 양육자가 동일한 설문지를 다시 작성하였다. 총 43명의 환아가 연구 대상에 포함되었으며, Child Oral Health Impact Profile(COHIP)과 Family Impact Scale(FIS)의 대한민국 버전이 설문에 사용되었다. COHIP과 FIS 점수 모두 술 전에 비하여 술 후에 개선되었다. 성별은 COHIP 및 FIS 점수의 개선에 별다른 영향을 주지 않았으며, 연령은 COHIP 점수의 개선에 영향을 주지 않았다. 그러나 어린 환아의 경우 술 전 FIS 점수가 더 양호한 것으로 나타났다. 치수치료를 한 경우에는 COHIP 점수가 더 크게 개선되었으며, 구치부 기성금속관 수복을 한 경우에는 FIS 점수의 개선 정도가 적었다. 전치부 심미수복 여부와 전치부 조기 발거 여부는 COHIP 및 FIS 점수의 개선 정도에 영향을 주지 않았다. 결론적으로, 전신마취 또는 정주진정 하 치과치료는 주 양육자가 인식하는 환아의 구강 건강과 관련된 삶의 질을 개선시킨다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제23권3호
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• pp.154-160
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• 2012

Objectives : The purpose of this study was to investigate clinical characteristics of children and adolescents with autism spectrum disorders (ASDs) using methylphenidate (MPH). Methods : Retrospective review of the charts of 79 children and adolescents with ASDs, who visited the Department of Child and Adolescent Psychiatry of Seoul National Hospital, from July 2010 to July 2011, was conducted. Changes in illness severity and improvement were measured using the Clinical Global Impression-Severity of illness (CGI-S) and Clinical Global Impression-Improvement (CGI-I) Scales. Results : We found that MPH was prescribed in 23 (29.1%) children and adolescents. Of the 23 patients on MPH, 4 patients (17.4%) were on MPH monotherapy and 18 patients (78.3%) were using risperidone concomitantly. MPH was prescribed primarily for symptoms of hyperactivity and impulsivity in ASDs patients. The mean dosage of MPH was $26.2{\pm}11.1$mg/day and mean duration of treatment was $31.9{\pm}28.7$ months. Mean CGI-S score improved significantly from baseline to endpoint (from $5.4{\pm}0.6$ to $4.1{\pm}0.9$ ; p<.01). MPH was reported to be effective in 17 patients (17/23, 73.9%), and 10 patients (10/23, 43.5%) reported side effects. Side effects included decreased appetite (4/23, 17.4%), tic (2/23, 8.6%), sleep disturbances (2/23, 8.6%), headache (1/23, 4.3%) and irritability (1/23, 4.3%). Conclusion : The results of this study demonstrate that MPH may be used effectively and safely in children and adolescents with ASDs with hyperactivity and impulsivity. Future controlled trials are needed to confirm these findings.

• Child Health Nursing Research
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• 제19권1호
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• pp.21-28
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• 2013

목적 본 연구는 소아청소년 암환자를 대상으로 삶의 질 정도와 그 관련요인을 알아봄으로써, 삶의 질을 개선하기 위한 간호중재 개발의 기초자료를 제공하고자 시도되었다. 방법 대상자는 소아암 진단을 받고 서울 소재 1개 대학병원에서 외래 또는 입원치료중인 8-18세 소아청소년 암환자 67명과 그 부모 67명인 총 134명이었다. 삶의 질은 Varni 등(2002)의 The PedsQL 3.0 Cancer Module을 사용하여 소아청소년 암환자와 그 부모를 대상으로 측정하였다. 삶의 질 관련 요인은 소아청소년 암환자와 그 부모의 일반적 특성과 질병관련 특성으로 하였다. 결과 소아청소년 암환자의 삶의 질 점수는 평균 75.07점, 부모가 보고한 자녀의 삶의 질 점수는 64.40점으로, 부모가 보고한 삶의 질이 소아청소년 암환자가 보고한 삶의 질보다 낮았다. 8-12세 소아 암환자가 보고한 삶의 질 점수는 평균 78.04점, 13-18세 청소년 암환자의 삶의 질 점수는 평균 71.62점으로 소아에 비해 청소년의 삶의 질 정도가 낮았다. 소아청소년 암환자와 부모의 일반적 특성에 따른 소아청소년 암환자의 삶의 질은 소아암환자가 보고한 삶의 질 점수와 부모가 보고한 삶의 질 점수 모두에서 유의한 차이가 없었다. 소아청소년 암환자의 질병관련 특성에 따른 삶의 질은 소아청소년 암환자가 보고한 삶의 질 점수와 부모가 보고한 삶의 질 점수 모두에서 유의한 차이가 없었다. 결론 소아청소년 암환자의 삶의 질은 소아청소년 암환자가 인지하는 정도와 부모가 인지하는 정도에 차이가 있으며, 소아와 청소년 사이에도 차이가 있었다.

• 대한간호학회지
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• 제9권1호
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• pp.9-22
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• 1979

The major purpose of this study was to compare the state anxiety of surgical patients by sex (male/female), area of operation (sex-organ/non sex-organ), and family planning (having the plan of child-bearing/having no plan of child-bearing). One hundred sixty patients who were to get surgical operation were equally divided into eight groups resulted from combination of variables of sex, area of operation, and family planning, The state anxiety of surgical patients was measured in terms of the discrepancy score between the state anxiety score on the State-Trait Anxiety Inventory (STAI) administered at a day before operation and the trait anxiety score on it which was administered at a day before discharge. In order to test statistically the differences among meant scores of the state anxiety obtained by eight groups, multiple comparisons were carried out by Scheffe method. The results of this study led to the conclusions that, (1) there was no significant sex difference in the state anxiety of surgical patients, when the area of operation and the family planning variables were disregarded, (2) the state anxiety of patients who were to get operation of their sex-organ was significantly higher than that of patients who were to get operation on the parts other than their sex-organ, when variables of the sex and the family planning were not taken into account, (3) there was no significant sex difference in the state anxiety of patients who were to Bet operation on the parts other than their sex-organ, when the family planning variable was disregarded, (4) the state anxiety of female patients who were to get operation on their sex-organ was significantly higher than the stale anxiety of male patients who were to get operation on their sex-organ, when the family planning variable was not taken into account.

• Radiation Oncology Journal
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• 제33권4호
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• pp.276-283
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• 2015

Purpose: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. Materials and Methods: Between 1998 and 2011, 45 patients received hepatic re-irradiation with high dose 3D-CRT in Samsung Medical Center. After excluding two ineligible patients, 43 patients were retrospectively reviewed. RT was delivered with palliative or salvage intent, and equivalent dose of 2 Gy fractions for ${\alpha}/{\beta}=10Gy$ ranged from $31.25Gy_{10}$ to $93.75Gy_{10}$ (median, $44Gy_{10}$). Tumor response and toxicity were evaluated based on the modified Response Evaluation Criteria in Solid Tumors criteria and the Common Terminology Criteria for Adverse Events (CTCAE) ver. 4.0. Results: The median follow-up duration was 11.2 months (range, 4.1 to 58.3 months). An objective tumor response rate was 62.8%. The tumor response rates were 81.0% and 45.5% in patients receiving ${\geq}45Gy_{10}$ and $<45Gy_{10}$, respectively (p = 0.016). The median overall survival (OS) of all patients was 11.2 months. The OS was significantly affected by the Child-Pugh class as 14.2 months vs. 6.1 months (Child-Pugh A vs. B, p < 0.001), and modified Union for International Cancer Control (UICC) T stage as 15.6 months vs. 8.3 months (T1-3 vs. T4, p = 0.004), respectively. Grade III toxicities were developed in two patients, both of whom received ${\geq}50Gy_{10}$. Conclusion: Hepatic re-irradiation may be an effective and tolerable treatment for patients who are not eligible for further local treatment modalities, especially in patients with Child-Pugh A and T1-3.

• Child Health Nursing Research
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• 제21권2호
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• pp.123-130
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• 2015

Purpose: The purpose of this study was to understand the intellectual and psychological features of children with Moyamoya disease who were patients in the Department of Pediatric Neurosurgery of Severance Hospital. Methods: From December 2010 through December 2012, 63 patients with diagnoses of Moyamoya disease and 59 children in a normal group were enrolled. This study was conducted using the Korean-Wechsler Intelligence Scale for Children, Rey-Kim Memory Test for children, Korean Child Behavior Checklist and Pediatric Quality of Life Inventory$^{TM}$4.0. Results: The results showed that the intellectual and psychological profiles of children with Moyamoya disease were lower than the average of the normal control group. The tested patients showed significantly lower scores for Performance Intelligence Quotient cognition level. Also, in terms of quality of life, children with Moyamoya disease had lower levels of physical and school functionality. The results were in line with those of previous studies involving psychological tests of children with chronic diseases. Conclusion: Considering the intellectual and psychological characteristics of children with Moyamoya disease, integrated psychological intervention plans including elements such as supportive therapy for patients and programs for parental education are required.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제31권5호
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• pp.381-385
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• 2009

Objective : The objective of this study was to compare the surgical techniques for the correction of congenital cleft palate. Techniques and approaches : Four-hundred-sixity patients operated between 1993 and 2008 were included in this study. The collected data were age, sex, operating time, admission days, and complications. The comparison between techniques were done by independent t-test. Results: The majority (86.9 %) of patients were received the operation later than 1.5 years old. The distribution of each surgical technique was 43.8 % by Bardach palatoplasty, 11.9 % by Furlow palatoplasty, 1.8 % by Veau palatoplasty, and 42.4 % by the new technique developed by us. Postoperative complication such as wound dehiscence, formation of oro-nasal fistulas in the soft and hard palates were shown in 23.0 % of Bardach technique, 44.2 % of Furlow technique, and 37.5 % of Veau technique. However, only 5.4 % of patients were shown complications in our technique (P<0.001). The operation time was recorded 70 minutes under new technique while the others were 110 minutes (P<0.001). The clinical treatment at hospital was required 7.4 days for our technique and 11.3-15.5 days for the other methods. Conclusion : The surgical treatment of congenital cleft palate in Mongolia was conducted later than proper timing for surgery. As the results were indicated, our new technique should be considered for the correction of cleft palate in old aged patients.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권3호
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• pp.143-149
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• 2019

Background: Uncooperative behavior of children due to dental anxiety may interfere with the effective delivery of dental care and compromise the quality of treatment provided. Injection of local anesthesia is one of the most anxiety-inducing stimuli in pediatric dentistry. This study aimed to compare the efficacy of a child-friendly device, having a combined effect of vibration and distraction, with the conventional method of injection on pain, anxiety, and behavior of pediatric patients aged 6-11 years. Methods: This randomized, crossover, split-mouth study included 30 children requiring a bilateral inferior alveolar nerve block. The children were equally divided into two groups: group 1, aged 6-8 and group 2, aged 9-11 years. All children were injected with anesthesia using the conventional and device method in two separate sessions. They were assessed for anxiety by measuring the pulse rate before and during the administration of local anesthesia. Behavior was assessed using Faces, Legs, Activity, Cry, Consolability (FLACC) scale, and the child's experience while receiving anesthesia was assessed using the Wong Bakers Pain Rating Scale. Results: Results showed that the children who received local anesthesia using the device method had a lower mean pulse rate, FLACC scores, and pain rating scores than those who received local anesthesia using the conventional method. Conclusion: The device method was more effective than the conventional method in managing pain, anxiety, and behavior of patients aged 6-11 years. The device is a cost effective, simple, and child-friendly product for administrating local anesthesia in pediatric patients.

• Clinical Endoscopy
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• 제56권5호
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• pp.578-589
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• 2023

Background/Aims: The safety of endoscopic retrograde cholangiopancreatography (ERCP) in hepatic cirrhosis and the impact of Child-Pugh class on post-ERCP complications need to be better studied. We investigated the post-ERCP complication rates in patients with cirrhosis compared with those without cirrhosis. Methods: We conducted a literature search of relevant databases to identify studies that reported post-ERCP complications in patients with hepatic cirrhosis. Results: Twenty-four studies comprising 28,201 patients were included. The pooled incidence of post-ERCP complications in cirrhosis was 15.5% (95% confidence interval [CI], 11.8%-19.2%; I²=96.2%), with an individual pooled incidence of pancreatitis 5.1% (95% CI, 3.1%-7.2%; I²=91.5%), bleeding 3.6% (95% CI, 2.8%-4.5%; I²=67.5%), cholangitis 2.9% (95% CI, 1.9%-3.8%; I²=83.4%), and perforation 0.3% (95% CI, 0.1%-0.5%; I²=3.7%). Patients with cirrhosis had a greater risk of post-ERCP complications (risk ratio [RR], 1.41; 95% CI, 1.16-1.71; I²=56.3%). The risk of individual odds of adverse events between cirrhosis and non-cirrhosis was as follows: pancreatitis (RR, 1.25; 95% CI, 1.06-1.48; I²=24.8%), bleeding (RR, 1.94; 95% CI, 1.59-2.37; I²=0%), cholangitis (RR, 1.15; 95% CI, 0.77-1.70; I²=12%), and perforation (RR, 1.20; 95% CI, 0.59-2.43; I²=0%). Conclusions: Cirrhosis is associated with an increased risk of post-ERCP pancreatitis, bleeding, and cholangitis.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제11권2호
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• pp.262-281
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• 2000

본 논문은 사춘기를 전후하여 발병하는 정신분열병의 또래 관계에 관해 사례 연구와 문헌 고찰을 통해 정리한 논문이다. 정신분열병의 예후를 결정하는 가장 중요한 인자로서 발병 전 대인관계 양상과 적응 정도가 중요하며, 교사가 평가한 학교 생활과 또래 관계가 정신분열병의 발병 및 경과를 예측하는 데 결정적인 역할을 하는 것으로 밝혀졌다. 정신분열병 환자의 자식들을 대상으로 한 고위험군 연구(high-risk study)와 장기간 추적 연구(long-term follow-up study)들을 통해 정신분열병 발병에 관여하는 전후기 아동기 성격적 ${\cdot}$ 행동적 특성에 대해서 기술하였고, 정신분열병에 발병하고 난 후 나타나는 대인관계 양상과 병태생리에 대해서 서술하였으며, 이를 사회화(socialization)의 관점에서 통합하려는 시도를 소개하였다. 끝으로 사춘기에 발병한 정신분열병 환자들의 대인관계 양상을 사례별로 정리하고, 향후 진행되어야 할 연구 과제에 대해서 제시하였다.