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작업환경을 위한 TLV의 근거 - PERCHLOROMETHYL MERCAPTAN(l)

  • Kim, Chi-Nyeon
    • 월간산업보건
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    • s.273
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    • pp.40-43
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    • 2011
  • Perchloromethyl mercaptan에 대한 직업적 노출기준으로 TLV-TWA 0.1 ppm(0.76 mg/$m^3$)으로 권고한다. TLV-TWA 0.1 ppm(0.76 mg/$m^3$) 은 눈과 코의 자극 그리고 불쾌한 냄새로 인한 불편함의 가능성을 최소화하는 수준이다. Perchloromethyl mercaptan에 대한 동물 노출 실험연구와 근로자들의 노출연구 자료는 매우 제한적이다. 사고로 확인되지 않은 농도에 근로자들이 노출된 경우, 발견된 증상과 징후는 눈, 목, 가슴에 심한 자극과 기침, 눈물, 호흡곤란, 메스꺼움, 구토, 빈맥, 청색증, 경련 그리고 폐부종에 의한 사망이다. Perchloromethyl mercaptan을 활용하는 생산설비에서 TLV-TWA 0.1 ppm 이하 농도의 증기에 노출되었을 때 질병을 유발하였다는 보고는 없었다. 피부흡수, 발암성 그리고 TLV-STEL을 권고하기 위한 유용한 자료는 충분하지 않다.

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Experimental behaviour of circular concrete filled steel tube columns under lateral cyclic loading

  • Cao, Vui Van;Vo, Cuong Trung;Nguyen, Phuoc Trong;Ashraf, Mahmud
    • Earthquakes and Structures
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    • v.21 no.5
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    • pp.445-460
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    • 2021
  • This study experimentally explored the behaviour of 12 concrete filled steel tube (CFST) and steel tube columns subjected to lateral cyclic loading. The L/D ratio was 12.3 while D/t ratios were 45.4, 37.8 and 32.4, classifying these 12 specimens into 3 groups. Each group included 3 CFST and 1 steel tube columns and were tested to failure. The experimental results indicated that CFST specimens reached the state of 'collapse prevention' (drift 4%) prior to the occurrence of local buckling. Strength degradation of CFST specimens did not occur up to the failure by buckling. This showed the favourable characteristic of CFST columns in preventing collapse of structures subjected to earthquakes. The high energy absorption capability in the post collapse limit state was appropriate for dissipating energy in structures. Compared to steel tube columns, CFST columns delayed local buckling and prevented inward buckling. Consequently, CFST columns exhibited their outstanding seismic performance in terms of the increased ultimate resistance, capacity to sustain 2-3 additional load cycles and significantly higher drift. A simple and reasonably accurate model was proposed to predict the ultimate strength of CFST columns under lateral cyclic loading.

Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer

  • Lin, Hongxia;Yoo, Jin-Wook;Lee, Chi-Ho;Kim, Dae-Duk
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.291.2-292
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    • 2003
  • The purpose of this study was to investigate the transport characteristics of passage cultured l1uman nasal epithelial cell monolayers grown on Transwell@ inserts using liquid-covered culture (LCC) method. The monolayer of passage 2 and 3 exhibited tight barrier (TEER>1,000 ohmxcm$^2$) in 2-3 days after seeding. In the morphological studies by actin staining and SEM/TEM, the existence of tight junction was clearly observed. (omitted)

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Eutrophication and Freshwater Red-tide Algae on Early Impoundment Stage of Jeolgol Reservoir in the Paikryeong Island, West Sea of South Korea (백령도 절골저수지의 부영양화와 담수적조)

  • Lee, Heung-Soo;Hur, Jin;Park, Jae-Chung;Shin, Jae-Ki
    • Korean Journal of Ecology and Environment
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    • v.39 no.2 s.116
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    • pp.271-283
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    • 2006
  • A systematic water quality survey was conducted in August, 2005 for a drinking water supply reservoir (the Jeolgol reseuoir located in an island), which is at an early stage of impoundment, to investigate the causes of water color deterioration of the reservoir and the clogging of filter beds of a water treatment plant. The reservoir shape was simple and its average depth was 5.5 m, increasing from upreservoir toward the downreservoir end near the dam. Dissolved oxygen (DO) and chloropllyll-a (chi-a) showed a large variation while water temperature had a smaller range. Transparency ranged from 0.6 to 0.9 m (average 0.7 m). The average value of turbidity was 9.3 NTU, ranging from 8.0 ${\sim}$ 12.1 NTU. The transparency and the turbidity appear to be affected by a combination of biological and non-biological factors. The poor transparency was explained by an increase of inorganic colloids and algal bloom in the reservoir. The blockage of the filter bed was attributed to the oversupply of phytoplanktons from the reservoir. The range and the average concentration of chi-a within the reservoir were 31.6 ${\sim}$ 258.9 ${\mu}g\;L^{-1}$, 123.6 ${\mu}g\;L^{-1}$ for the upper layer, and 17.0 ${\sim}$ 37.4 ${\mu}g\;L^{-1}$, 26.5 ${\mu}g\;L^{-1}$ for the bottom layer, respectively. A predominant species contributing the algal bloom was Dinophyceae, Peridinium bipes f. occultatum. The distribution of Peridinium spp. was correlated with chi-a concentrations. The standing crop of phytoplankton was highest in the upreservoir with $8.5\;{\times}\;103\;cells\;mL^{-1}$ and it decreased toward the downresevoir. Synedra of Bacillariophyceae and Microcystis aeruginosa of Cyanophyceae appeared to contribute to the algal bloom, although they are not dominated. It is mostly likely that sloped farmlands located in the watershed of the reservoir caused water quality problems because they may contain a significant amount of the nutrients originated from fertilizers. In addition, the aerators installed in the reservoir and a shortage of the inflowing water may be related to the poor water quality. A long-term monitoring and an integrated management plan for the water quality of the watersheds and the reservoir may be required to improve the water quality of the reservoir.

Relation between Rainfall and Phytoplankton Community in Daechung Reservoir (대청호에서 강우와 식물플랑크톤 군집의 관계)

  • Joung Seung-Hyun;Ahn Chi-Yong;Choi Aeran;Jang Kam-Yong;Oh Hee-Mock
    • Korean Journal of Environmental Biology
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    • v.23 no.1
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    • pp.57-63
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    • 2005
  • The phytoplankton community, environmental factors, and rainfall were investigated from July to October in 2001 and 2003 on Dam site in Daechung Reservoir. The monthly average rainfall in the investigated period were 91.3 and 265.3 mm in 2001 and 2003, respectively. The maximum chlorophyll a concentration was observed higher at 131.5 ㎍ L/sup -1/ in 2003 than at 45.4 ㎍ L/sup -1/ in 2001. The cyanobacterial number in 2001 was counted up to over 200,000 cells mL/sup -1/, which was much higher than the maximum number of 49,000 cells mL/sup -1/ in 2003. The relative abundance of cyanobacteria in the phytoplankton community was about 97% in 2001 and 74% in 2003. Microcystis spp. were absolutely dominant species in 2001, while a couple of cyanobacteria such as Oscillatoria spp., Phormidium spp. Chroococcus spp. and Microcystis spp. were dominant species in 2003. Consequently, it seemed that rainfall affected the diversity of phytoplankton species and decreased the density of bloom-forming cyanobacteria.

BREEDING TOBACCO (NICOTIANA TABACUM L.) RESISTANT TO POTATO VIRUS Y IN KOREA I. INHERITANCE OF RESISTANCE TO POTATO VIRUS Y OF FLUE-CURED TOBACCO VARIETY MCNAIR 30 (연초 (Nicotiana tabacum L.) 감자바이러스Y 저항성 품종육성 I. 황색종 품종 McNair30의 감자바이러스Y 저항성유전)

  • 정윤화;정석훈;금완수;최상주;이승철
    • Journal of the Korean Society of Tobacco Science
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    • v.6 no.2
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    • pp.185-189
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    • 1984
  • To classify the inheritance of resistance to potato virus Y, crosses between susceptible flue-cured tobacco variety NC 95 and resistant variety McNair 30 were conducted. The parents, $F_1$ plants, $F_2$ populations, and haploid plants derived from anthers of $F_1$ plants were screened for a resistance of two potato virus Y strains (PVY-VB and PVY-VN) isolated in Korea. The Chi-square values for the $F_3$ populations and haploids of $F_1$ fitted 1 :3 and 1 :1 ratios of resistant to susceptible for two strains, respectively. Therefore, it was found that the resistance of McNair 30 for the potato virus Y was controlled by a single recessive gene. Moreover the resistance to two strains screened was inherited dependently.

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Linkages of nursing Diagnosis, Nursing Intervention and Nursing Outcome Classification of Breast Cancer Patients using Nursing Database (간호데이터베이스를 이용한 유방암환자의 간호진단, 간호중재, 간호결과 분류연계)

  • Chi, Mi-Kyung;Chi, Sung-Ai
    • Journal of Korean Academy of Nursing Administration
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    • v.9 no.4
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    • pp.651-661
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    • 2003
  • Purpose: This is the descriptive research project of which purpose is to acquire the practice, research, and educational data by establishing the database after confirming, classifying, and relating the nursing diagnosis, nursing intervention, and nursing outcome of Breast cancer patients by using the Yoo Hyung-sook's(2001) related 3N database model as the tool. Method : The Nursing Data occurring on Breast cancer patients nursing process was mapped to nursing diagnosis of NANDA, nursing interventions of NIC, nursing outcomes of NOC the 3N database linkage database which is related with the nursing process that was developed by using Yoo Hyung-sook's(2001). Result : 1. The nursing diagnosis were totally 505, and 26 articles of the nursing diagnosis were applied among 149 nursing diagnosis classification systems. 2. As for the nursing intervention, 250 articles(5l.4%) of nursing intervention were applied among 486 nursing intervention classification systems. 3. Regarding the nursing outcome, 28 articles(1l.2%l of the nursing outcome were applied among 250 nursing outcome classification systems. Conclusion: The result of this research in which the relating among the nursing diagnosis, nursing intervention, and nursing outcome of Breast cancer patients by using 3N nursing database was established is thought to be applied in the research and practice as well as to be utilized in the lecture or practice of the nursing process.

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Changes in the Growth and Quality of Creeping Bentgrass (Agrostis palustris Huds. 'Penn A1') Following Gibberelinic Acid (GA3) Treatment (지베렐린산(GA3) 처리에 따른 크리핑 벤트그래스 (Agrostis palustris Huds. 'Penn A1')의 생장 및 품질 변화)

  • Woo-Sung Kim;Tae-Wooung Kim;Young-Sun Kim;Chi-Hwan Lim
    • Korean Journal of Environmental Agriculture
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    • v.42 no.4
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    • pp.389-395
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    • 2023
  • This study evaluated the effects of gibberellic acid (GA3) on the growth and quality of creeping bentgrass (Agrostis palustris Huds.). Experimental treatments included a No application of fertilizer and GA3 (NFG) Control [3 N active ingredient (a.i.) g/m2], 0.3GA3 (GA3 0.3 a.i. mg/m2/200 mL), 0.6GA3 (GA3 0.6 a.i. mg/m2/200 mL), 1.2GA3 (GA3 1.2 a.i. mg/m2/200 mL), and 2.4GA3 (GA3 2.4 a.i. mg/m2/200 mL). Additionally, the study included a 1.5N+GA3 experiment with similar GA3 treatments combined with 1.5N a.i. g/m2 : NFG, Control (3N a.i. g/m2), 1.5N+ 0.3GA3 (1.5N a.i. g/m2+GA3 0.3 a.i. mg/m2/200 mL), 1.5N+0.6GA3 (1.5N a.i. g/m2+GA3 0.6 a.i. mg/m2/200 mL), 1.5N+1.2GA3 (1.5N a.i. g/m2+GA3 1.2 a.i. mg/m2/ 200 mL), and 1.5N+2.4GA3 (1.5N a.i. g/m2+GA3 2.4 a.i. mg/m2/200 mL). Compared to the NFG, turf color index chlorophyll content was not significantly different (p< 0.05). However, shoot length in 1.2GA3, 2.4GA3, 1.5N+0.3GA3, 1.5N+0.6GA3, 1.5N+1.2GA3, and 1.5N+2.4GA3 treatments increased by 0.8%, 10.6%, 5.15%, 8.3%, 13.5 %, and 21.6%, respectively, compared to the control. As compared to the control, clipping yield in 1.5N+1.2GA3 and 1.5N+2.4GA3 treatments increased by 7.1% and 14.3 %, respectively. These results indicated that GA3 application increased shoot length, with the 1.2GA3 treatment showing shoot length similar to the control (3N a.i. g /m2 ).

Anti-adipogenic Effects of Vibration with Varied Frequencies on 3T3-L1 Preadipocytes (3T3-L1 지방전구세포에 대한 다양한 주파수 진동의 지방 생성 억제 효과)

  • Lee, Yeong Hun;Lee, Seok-Ho;Jung, Haebin;Jung, Yong Chan;Kim, Min Hwan;Lee, Eun Mi;Kim, Chi Hyun
    • Journal of Biomedical Engineering Research
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    • v.42 no.1
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    • pp.18-24
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    • 2021
  • Vibration is a mechanical cue that can be applied to adipose tissues for the purpose of treating obesity. However, the exact correlation between vibration and other anti-adipogenic pathways, such as development of cytoskeleton and apoptosis, remains unknown. The objective of this study was to investigate the unknown anti-adipogenic effects of vibration with varied frequencies on preadipocytes. 3T3-L1 preadipocytes were cultured in Dulbecco's modified Eagle's medium (DMEM) containing 5% calf serum at 37 ℃ with 5% CO2 in a humidified incubator. Vibration was generated using Arduino Uno microcontroller and vibration motor module with 1 V DC, and applied to preadipocytes for 3 days. Frequency conditions were set to 20, 55, and 90 Hz. Then, the expressions of p38 pathway, ROCK-1, α-actinin, Bax, Bcl-2, caspase-9, 8, and 3 were analyzed with western blot. As a result, p38 pathway was inhibited in 55 and 90 Hz while ROCK-1 and α-actinin were expressed in 20 Hz. Caspase-3, a terminal apoptotic factor, was activated in 20 Hz via extrinsic pathway rather than intrinsic pathway. Results suggest that various frequencies of vibration can inhibit adipogenesis via different pathways which sheds light on future mechanotransduction applications of vibration for the treatment of obesity.

Effects of Organic Nutrients on Chitinase Production in Minimal Media (배양액중의 유기영양물이 Chitinase 생산에 미치는 영향)

  • Jang, Ji-Yun;Kim, In-Cheol;Jang, Hae-Chun
    • Microbiology and Biotechnology Letters
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    • v.32 no.4
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    • pp.366-370
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    • 2004
  • Four chitinase producing bacteria, Arthrobacter nicotinae CH4, Arthrobacter nicotinae CHI3, Arthrobacter sp. CH5 and Micrococcus sp. CH3, were isolated from small crabs and shrimps. We investigated the optimum medium condition for the production of enzyme and high cell mass. The preferable medium composition was as follows: colchitin 0.1 %(w/v), glycerol 0.25%(w/v) and yeast extract 0.05%(w/v) in minimal midium ($K_{2}HPO_{4}$ 0.7 g/l, $KH_{2}PO_{4}$ 0.3 g/l, $MgSO_{4}{\cdot}5H_{2}O$ 0.5 g/l, $FeSO_{4}}{\cdot}7H_{2}O$ 0.01 g/l, $ZnSO_{4}$ 0.001 g/l, $MnCI_2$ 0.001 g/l, pH 7.0). This cell culture medium could be used directly as sample for measuring chitinase activity. Because it hardly conreducing sugar such as glucose (blank value=0), the detected reducing sugar can be considered as a chitinase reaction product. The results can be used for easy preparation method for determination of enzyme activity and analysis of enzyme-substrate reaction in step of screening of chitinase producing bacteria.