• Molecular & Cellular Toxicology
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• v.4 no.4
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• pp.318-322
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• 2008

Obesity is an increasing worldwide health problem that is strongly related to the imbalance of food intake and energy metabolism. It was well-known that several substances in the hypothalamus regulate food intake and energy metabolism. We planned an integrative study to elucidate the mechanism of the development of obesity. Firstly, to find candidate genes with the marvelous effect, the different expression in the hypothalamus between ob/ob and 48-h fasting mice was investigated by using DNA microarray technology. As a result, we found 3 genes [peroxisome proliferator activated receptor, gamma, coactivator 1 alpha (Ppargc1a), calmodulin 1 (Calm1), and complexin 2 (Cplx2)] showing the different hypothalamic expression between ob/ob and 48-h fasting mice. Secondly, a genetic approach on PPARGC1A gene was performed, because PPARGC1A acts as a transcriptional coactivator and a metabolic regulator. Two hundred forty three obese female patients with body mass index (BMI)${\geq}$25 and 285 control female subjects with BMI 18 to<23 were recruited according to the Classification of Korean Society for the Study of Obesity. Among the coding single nucleotide polymorphisms (cSNPs) of PPARGC1A, 2 missense SNPs (rs8192678, Gly482Ser; rs3736265, Thr612Met) and 1 synonymous SNP (rs3755863, Thr528Thr) were selected, and analyzed by PCR-RFLP and pyrosequencing. For the analysis of genetic data, chi-square ($X^2$) test and EH program were used. The rs8192678 was significantly associated with obese women (P<0.0006; odds ratio, 1.5327; 95% confidence interval, 1.2006-1.9568). Haplotypes also showed significant association with obese women ($X^2$=33.28, P<0.0008). These results suggest that PPARGC1A might be related to the development of obesity.

• The Journal of the Korean dental association
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• v.47 no.12
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• pp.823-829
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• 2009

Purpose : The aim of this study was to evaluate the survival rate of sintered porous-surfaced implants placed in the edentulous posterior mandibles, in relation to implant length and diameter, crown-to-implant ratio, and types of prostheses, for a maximum of eight years of functioning. Material and Methods : The study group consisted of 43 partially edentulous patients who visited Catholic University Hospital of Daegu and one private dental clinic. A total of 122 sintered porous-surfaced implants n $Endopore^{(R)}$ (Inn ova Life Sciences, Toronto, Ontario, Canada) -- were placed in the edentulous posterior mandibles, Two diameter sizes (4.1 mm and 5.0 mm) and four lengths (5.0 mm, 7.0 mm, 9.0 mm, and 12.0 mm) were used. One hundred and three implants were splinted and 21 implants were nonsplinted. The survival rates of the implants in relation to length, diameter, crown-to-implant ratio, and types of prostheses were investigated. Statistical data were analyzed using SPSS Win.Ver 14.0 software with the Chi-square test. Results : The survival rate of the 4.1mm diameter implants was 100% and 91.2% for the 5.0mm diameter implants. The survival rates of the implants of differing diameters were found to be statistically different (p=0.005). The survival rates of both the 5.0mm and 7.0 mm length implants were 100%. The survival rate of the 9.0mm length implants was 97.9% and for the 12.0mm length implants was 95.1%. There was no statistical difference in survival rates for the differing lengths of implants. Of the 103 prostheses that were splinted, the survival rate was 98.0%. The survival rate of splinted prostheses was higher than that of the non-splinted prostheses, but was found to be not statistically different. There were no failed cases when the crown-to-implant ratio was under 1.0. When the crown-to-implant ratio was between 1.0 and 1.5, the failure rate of the implants was 6.7%. No failure was recorded with the ratio range of 1.5 to 2.0. Relative to the crown-to-implant ratio of 1.0, the failure rates were statistically different (p=0.048). Discussion and Conclusion : The cumulative survival rate of the porous-surfaced implants placed in the edentulous posterior mandibles was 97.5%. Short porous-surfaced implants showed satisfactory results after a maximum of nine years of functioning in the edentulous posterior mandibles.

• Journal of Korean Tunnelling and Underground Space Association
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• v.3 no.3
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• pp.15-29
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• 2001

For the pertinent use of NMT method, both characteristics of joints (JRC, JCS and ${\phi}_r$) and characteristics of rock mass (Q-Value) must be investigated carefully. The main objective of the study presented is to investigate how sensitive the predicted behaviour of an underground excavation is to various realistic assumptions about some input parameter for the jointed rock mass. Joint pattern in the tunnel is predicted by statistical approach (chi-square test). In this paper, sensitivity studies involving in joint characteristics were carried out. The parametric studies involving change in Barton-Bandis joint model have shown that JCS is relatively insensitive to JRC and ${\phi}_r$. An increase in JRC value may not, according to the Barton-Bandis model, necessarily lead to a decrease in displacement. The importance of dilation in predicting the behaviour of a rock mass around an excavation is emphasized from a comparison of the Barton-Bandis joint behaviour model with the Mohr-Coulomb model. The Barton-Bandis model predicted higher stress, which allow for the build-up of stress caused by dilatant behaviour.

• Journal of Korea Entertainment Industry Association
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• v.15 no.8
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• pp.305-313
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• 2021

This study aimed to discover the satisfaction of physical therapy students' major education and the perception of the occupational value of physical therapists and provided basic data to be used for career guidance of college students majoring in physical therapy. A questionnaire survey was conducted online to collect data on participants' general characteristics, motivation for joining the Department of Physical Therapy, satisfaction with their academic majors, and perception of occupational and social value of physical therapy. Using SPSS version 28, frequency and correlation analyses were undertaken and a Chi-square test performed for 174 respondents. As a result of the study, there was no significant difference in major education satisfaction according to gender and grade with as each p-value .368, .685. There was a significant difference in perception of job value according to gender as a p-value .032, and there was no significant difference in the p-value according to gender of .463. There was no significance difference in social job perception according to gender and grade with as each p-value .483, .077. There was positive correlation with the correlation coefficient of .483 that analyzed the level of perception of occupational value of physical therapists according to satisfaction of major education. In conclusion, students's high satisfaction with their academic majors exhibited considerable correlation with their perceived high occupational value of physical therapy. It is believed that these results can be used in career guidance for college students majoring in physical therapy.

• Journal of Environmental Health Sciences
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• v.42 no.6
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• pp.396-408
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• 2016

Objectives: The purposes of this study were to determine the relationship between the prevalence of allergic diseases and urinary cadmium concentration among children from six to 12 years of age, and to evaluate the association between cadmium in urine and other immunologically related factors in two elementary schools with different environmental conditions. Methods: Data on physician-diagnosed prevalence over the past 12 months and potential risk factors for allergic disease were collected from survey results drawn from 236 children living in different regions (central urban vs. suburban) from April to July in 2014 by an ISAAC questionnaire. We analyzed cytokine levels in serum through enzyme-linked immunosorbent assay and urinary cadmium concentration by use of inductively coupled plasma mass spectrometry. Results: Concentrations of urinary cadmium in suburban and central urban children were $0.11{\pm}0.11ug/L$, $0.14{\pm}0.17ug/L$, respectively (p>0.05). Results from the analysis of the t-test and chi-square test showed that urinary cadmium levels were positively associated with environmental factors (paternal smoking status, passive smoking, traffic volume and experiences of outdoor odors) and individual genetic factors (parental allergic disease). Cadmium concentrations in urine were also positively associated with the prevalence of allergic disease and immune-related cytokines (eosinophils, IgE, IL-5, IL-33, IL-17). Conclusion: This study suggests that genetic factors (parental history of allergic diseases), environmental factors, and regional status (suburban and central urban) should be considered as probable factors increasing the concentration of urinary cadmium, which has the potential to influence the allergic disease prevalence of school-age children.

• Journal of Korean Society of Forest Science
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• v.87 no.3
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• pp.445-458
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• 1998

The present study focused on the vegetation structure and dynamics of Betula davurica forest were to provide the information for management, distribution and utilization of B. davurica forest in Mt. Chiri national park, southern Korea. The layer structure of B. davurica forest were consist of tree layer(18 species), middle layer(29 species), shrub layer(43 species) and herb layer(68 species). According to the importance value of stratification of layers, In tree layer, B. davurica dominant the highest value of 123.97%, Alnus hirsuta 49.04., Castanea crenata 25.58%, Quercus serrata 25.02%, Stewartia koreana 14.49%, in middle layer were B. davurica 70.81%, Q. serrata 37.74%, Fraxinus rhynchophylla 25.35% Lindera erythrocarpa 24.52%, S. koreana 18.86%, shrub layer were Sasa borealis 28.28%, L. erythrocarpa 24.94%, Rhus trichocarpa, 20.42%, Stephanandra incisa 19.90% and herb layer Schizandra chinensis 18.51%, Aster scaber 12.26%. Disporum smilacinum 10.63% etc, respectively. Results of chi-square test statistics based on presence-absence parameters, the positively associated species pair were Quercus variablis - Q. acutissima, Stewartia koreana - Symplocos paniculata, Acer pseudo-sieboldianum - Quercus mongolica. And covariation was calculated based on quantitative measure of density. The results showed that the association and covariation values among species not agreed with each other. The frequency distribution of DBH Betula davurica species showed reverse J-shaped, therefore it's seems to retrain as a dominant species. When predicting succession in Betula davurica forest, it is seedling and saplings were not richness, succession was governed by competition of hardwood species of subtree and tree layer.

• The Journal of the Korean dental association
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• v.50 no.4
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• pp.203-210
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• 2012

Objective: The aim of this study was to investigate the incidence of the C-shaped canal of permanent mandibular second molar (PMSM) in Korean sub-population using Cone-Beam CT (CBCT) data and analyze the types of C-shaped canal. Materials & Methods: The protocol for this study was approved by the Institutional Review Board at the Pusan National University Hospital (E-2011039). Among the CBCT images taken of patients who visited the St. Bennedict Dental Hospital (Busan, Korea) from May 2008 to April 2011 for implant surgery and surgical removal of impacted teeth, high-quality CBCTs from 705 patients (361 male and 342 female) were screened and 607 PMSMs of 383 patients were evaluated retrospectively. All PMSMs were anatomically analyzed in detail by using image viewer software (EasyDent; Vatech). PMSMs were evaluated in the axial plane to investigate the shape of root and canals. The C-shaped canals were classified into five types. The total incidence, gender ratio, bilateral and unilateral appearance. and the correlation between right-side and left-side occurrences of C-shaped PMSMs were computed and compared statistically using the chi-square test. Results: Among the 607 PMSMs of 383 CBCTs of 187 females and 196 males, 198 PMSMs(32.6%) had C-shaped root and 158 PMSMs(26.0%) had C-shaped canals. The shape of C-shaped root canals at the furcalion level did not have significant change at the level of mid root (P<0.0001). Female had more prevalence of C-shaped root canals than male (P<0.0001). The prevalence of bilateral occurrence of C-shaped root canals was higher than unilateral occurrence. Conclusions: The occurrence of C-shaped PMSMs among a Korean population was 32.6% and was higher than other countries and ethnicities. Understanding the prevalence of PMSMs with a C-shaped root and/or canal in a Korean population may be useful for successful endodontic treatments.

• Journal of The Korean Association of Information Education
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• v.24 no.4
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• pp.369-378
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• 2020

This paper examines inquiries generated in three different online educational programs in Korea at the secondary educational level. Data covers 12,023 inquiries recorded during the first semester of 2019 and the compared groups among three programs are divided by four criteria: its type, period, inquirer, and the way of response. Statistical comparisons using Chi-square test suggest that there are significant differences in frequency rates of inquiries among three programs. First, 'Program A' has more inquiries by student themselves, mostly in the middle of the semester about the contents. Second, inquiries are more frequent for 'Program B' by the coordinating teachers about system-related or evaluation-related questions, either at the beginning or the end of the semester. Third, in the case of 'Program C', parents of health-impaired students are the main inquirers who ask admin-related questions at the beginning of the semester. With respect to the way of response to inquiries, more than 95% of inquiries are answered immediately for all three programs. These quantitative findings are also supported qualitatively, by face-to-face interviews with operators of the three programs. Results of this paper can be used for educational practitioners and experts when they design and operate the customized online educational programs with different purposes and different target-students in the future.

• The Journal of the Korea Contents Association
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• v.10 no.10
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• pp.267-273
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• 2010

The present study examined factors for current conditions of dental office manager in Korean dental clinic. 108 randomly selected members of Korean dental office manager responded to a questionnaire. A survey was conducted for a month from 1, June 2008, and the chi-square test and ANOVA were used in the statistical analysis. The findings of the study were as follows: The number of members depending on the type of occupation dental hospital was the highest number of members, members of the dental hygienist at the dental hospital number significantly higher. The career of dental office manager followed by 1-5 year in dental hospital, 5-10 year in dental network, 1-5 year in dental clinic accounting for 48%, 52.9%, 69.4%. The difficulty during duty performance are high expectation of owner in dental hospital, learning of dental office manager duty in dental clinic. The duty of dental office manager followed by customer service, appointment scheduling, telephone etiquette, treatment plan. Henceforth, it needs to standardize the Korean name of dental office manager and duty. Also, it have to an official certification system.

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.395-406
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• 2011

This study was to identify the obesity(BMI), health practices and oral health behaviors of university students and provide basic data for the development of a health promotion program for healthy campus communities. Total 177 students filled out a self-administered questionnaire. Data were analyzed for descriptive statistics, chi-square test and multivariate logistic regression to evaluate the effects of health practice and oral behaviors on obesity. This study shows that the prevalence of obesity was 27.7%. Univarate analysis demonstrated that gender, age, the preference of salt, sleep in every day, self-perceived general health, the visiting the dentist during the past year were significantly different according to BMI. In multivariable regression, preference of salt, sleep in every day, the visiting the dentist during the past year were independent predictors of BMI, after adjustment of gender and age. The findings of this study emphasize the importance of obesity prevention program in overall, eating habit, mental health and oral health behavior in students.